Browsing Publikasjoner fra Cristin - St. Olavs hospital by Title
Now showing items 710-729 of 1620
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‘I want to get back!’ A qualitative study of long-term critically ill patients’ inner strength and willpower: Back home after long-term intensive care
(Peer reviewed; Journal article, 2021)Aims and objectives To provide insights into what promotes and challenges inner strength and willpower in formerly critically ill patients back home after a long-term ICU stay. Background Critically ill patients demand ... -
Identification of a regulatory pathway governing TRAF1 via an arthritis-associated non-coding variant
(Peer reviewed; Journal article, 2023)TRAF1/C5 was among the first loci shown to confer risk for inflammatory arthritis in the absence of an associated coding variant, but its genetic mechanism remains undefined. Using Immunochip data from 3,939 patients with ... -
Identification of metastasis-associated microRNAs in serum from rectal cancer patients
(Peer reviewed; Journal article, 2017)MicroRNAs (miRNAs) are promising prognostic and diagnostic biomarkers due to their high stability in blood. Here we investigate the expression of miRNAs and other noncoding (nc) RNAs in serum of rectal cancer patients. ... -
Identification of novel cyanoacrylate monomers for use in nanoparticle drug delivery systems prepared by miniemulsion polymerisation – A multistep screening approach
(Peer reviewed; Journal article, 2022)Poly (alkyl cyanoacrylate) (PACA) polymeric nanoparticles (NPs) are promising drug carriers in drug delivery. However, the selection of commercially available alkyl cyanoacrylate (ACA) monomers is limited, because most ... -
Identification of the source of elevated hepatocyte growth factor levels in multiple myeloma patients
(Journal article; Peer reviewed, 2014)Background Hepatocyte growth factor (HGF) is a pleiotropic cytokine which can lead to cancer cell proliferation, migration and metastasis. In multiple myeloma (MM) patients it is an abundant component of the bone marrow. ... -
Identification of unhealthy alcohol use by self-report and phosphatidylethanol (PEth) blood concentrations in an acute psychiatric department
(Peer reviewed; Journal article, 2022)Background The use of standard screening methods could improve the detection rate of unhealthy alcohol use in patients admitted to psychiatric acute and emergency departments. The aim of the present study was to investigate ... -
IL-32 is induced by activation of toll-like receptors in multiple myeloma cells
(Peer reviewed; Journal article, 2023)Multiple myeloma (MM) is a hematological cancer characterized by accumulation of malignant plasma cells in the bone marrow. The patients are immune suppressed and suffer from recurrent and chronic infections. Interleukin-32 ... -
Imminent and Short-Term Risk of Death by Suicide in 7,000 Acutely Admitted Psychiatric Inpatients
(Peer reviewed; Journal article, 2022)Objective: To prospectively investigate the predictive value of diagnosis, suicidal behavior, and subjectively experienced depressed mood for imminent risk of suicide death. Methods: This prospective study included a ... -
Immune phenotype of tumor microenvironment predicts response to bevacizumab in neoadjuvant treatment of ER-positive breast cancer
(Peer reviewed; Journal article, 2020)Antiangiogenic drugs are potentially a useful supplement to neoadjuvant chemotherapy for a subgroup of patients with human epidermal growth factor receptor 2 (HER2) negative breast cancer, but reliable biomarkers for ... -
Impact of a FTO gene risk variant on variables of energy metabolism in adults with obesity class 2 and 3
(Journal article; Peer reviewed, 2019)Purpose The metabolic consequences of carrying a FTO obesity-promoting risk allele have not been fully elucidated and may be confounded by obesity per se. Against this background, we investigated the impact of FTO allele ... -
The impact of age on risk assessment, therapeutic practice and outcome in candidemia
(Peer reviewed; Journal article, 2019) -
The impact of air change rate on the air quality of surgical microenvironment in an operating room with mixing ventilation
(Peer reviewed; Journal article, 2020)Transmission of airborne microbe-carrying particles (MCPs) is one of the key factors causing surgical site infection during surgical procedures. In operating rooms (ORs) with mixing ventilation, air change rate may determine ... -
Impact of baseline coronary flow and its distribution on Fractional Flow Reserve prediction
(Journal article; Peer reviewed, 2019)Model‐based prediction of fractional flow reserve (FFR) in the context of stable coronary artery disease (CAD) diagnosis requires a number of modelling assumptions. One of these assumptions is the definition of a baseline ... -
Impact of COVID-19 pandemic lockdown on mental well-being of Norwegian adolescents during the first wave—Socioeconomic position and gender differences
(Peer reviewed; Journal article, 2021)Background: The lockdowns associated with the COVID-19 pandemic has been called a crisis in mental health, and adolescents may have been among the most affected. Comparing the first period of societal lockdown in spring ... -
Impact of different preanalytical conditions on results of lupus anticoagulant tests
(Peer reviewed; Journal article, 2019)Introduction: The currently recommended preanalytical conditions for lupus anticoagulant (LA) analysis require analyzing samples in fresh or freshly frozen platelet‐poor plasma. The aim of this study was to evaluate whether ... -
Impact of Food-Based Weight Loss Interventions on Gut Microbiome in Individuals with Obesity: A Systematic Review
(Peer reviewed; Journal article, 2022)The observation that the gut microbiota is different in healthy weight as compared with the obese state has sparked interest in the possible modulation of the microbiota in response to weight change. This systematic review ... -
The impact of gender, puberty, and pregnancy in patients with POLG disease
(Peer reviewed; Journal article, 2020)Objective To study the impact of gender, puberty, and pregnancy on the expression of POLG disease, one of the most common mitochondrial diseases known. Methods Clinical, laboratory, and genetic data were collected ... -
Impact of genotype-predicted CYP2D6 metabolism on clinical effects and tolerability of metoprolol in patients after myocardial infarction – a prospective observational study
(Peer reviewed; Journal article, 2020)Purpose The β-1 adrenergic receptor blocker metoprolol is primarily metabolized by the polymorphic enzyme cytochrome P 450 2D6 (CYP2D6), an enzyme with substantial genetic heterogeneity. Our purpose was to investigate the ... -
Impact of job adjustment, pain location and exercise on sick leave due to lumbopelvic pain in pregnancy: a longitudinal study
(Journal article; Peer reviewed, 2019)Objective: To identify factors associated with sick leave due to lumbopelvic pain (LPP) in pregnancy. Design: Prospective cohort study using participants from a randomized controlled trial (RCT) designed to study the ... -
Impact of KRAS, BRAF and microsatellite instability status after cytoreductive surgery and HIPEC in a national cohort of colorectal peritoneal metastasis patients
(Peer reviewed; Journal article, 2021)Patients with metastatic colorectal cancer (mCRC) carrying BRAF (mutBRAF) or KRAS mutation (mutKRAS) have an inferior prognosis after liver or lung surgery, whereas the prognostic role in the context of peritoneal metastasis ...