• Baseline and Exercise Predictors of VO2peak in Systolic Heart Failure Patients: Results from SMARTEX-HF 

      Karlsen, Trine; Videm, Vibeke; Halle, Martin; Ellingsen, Øyvind; Støylen, Asbjørn; Dalen, Håvard; Delagardelle, Charles; Larsen, Alf Inge; Hole, Torstein; Mezzani, Alessandro; Craenenbrock, EM; Beckers, Patrick; Pressler, Axel; Christle, JW; Winzer, Ephraim; Mangner, Norman; Woitek, Felix; Höllriegel, Robert; Snoer, Martin; Feiereisen, Patrick; Valborgland, Torstein; Linke, Axel; Prescott, Eva Irene Bossano (Journal article; Peer reviewed, 2019)
      Purpose To investigate baseline, exercise testing, and exercise training-mediated predictors of change in peak oxygen uptake (VO2peak) from baseline to 12-week follow-up (ΔVO2peak) in a post-hoc analysis from the SMARTEX ...
    • Biofeedback Treatment App for Pediatric Migraine: Development and Usability Study 

      Stubberud, Anker; Tronvik, Erling Andreas; Olsen, Alexander; Gravdahl, Gøril Bruvik; Linde, Mattias (Peer reviewed; Journal article, 2020)
      Objective The objective of this study was to develop and investigate the usability of a biofeedback treatment smartphone app for adolescent migraine sufferers. Background Biofeedback is effective in treating pediatric ...
    • Biological and Clinical Insights From Genetics of Insomnia Symptoms 

      Lane, Jacqueline M.; Jones, Samuel E.; Skogholt, Anne Heidi; Gabrielsen, Maiken Elvestad; Hveem, Kristian; Brumpton, Ben Michael; Zwart, John-Anker; Nielsen, Jonas Bille; Winswold, Bendik; Willer, Cristen J; Janszky, Imre; Johnsen, Marianne Bakke; Wood, Andrew R.; Strand, Linn B.; Bowden, Jack; Song, Yanwei; Patel, Krunal; Anderson, Simon G.; Beaumont, Robin N.; Bechtold, David A.; Cade, Brian E.; Kathiresan, Sekar; Little, Max A.; Loudon, Andrew S.; Purcell, Shaun; Richmond, Rebecca C.; Schormair, Barbara; Tyrrell, Jessica; Winkelmann, Juliane; Zhao, Cheng; Redline, Susan; Spiegelhalder, Kai; Kyle, Simon D.; Frayling, Timothy M.; Lawlor, Deborah A.; Rutter, Martin K.; Weedon, Michael N.; Saxena, Richa (Journal article; Peer reviewed, 2019)
      Insomnia is a common disorder linked with adverse long-term medical and psychiatric outcomes. The underlying pathophysiological processes and causal relationships of insomnia with disease are poorly understood. Here we ...
    • Biomarkers for Traumatic Brain Injury: Data Standards and Statistical Considerations 

      Huie, Russel J; Mondello, Stefania; Lindsell, Christopher J.; Antiga, L; Yuh, Esther; Zanier, Elisa; Masson, Serge; Rosario, Bedda; Ferguson, Adam; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne; Ackerlund, Cecilia; Adams, Hadie; Agnoletti, Vanni; Allanson, Judith; Amrein, Krisztina; Andaluz, Norberto; Azasevac, Antun; Antoni, Anna; Ardon, Hilko; Audibert, Gerard; Auslands, Kaspars; Azouvi, Philippe; Azzolini, Luisa; Baciu, Camelia; Badenes, Rafael; Bartels, Ronald; Barzo, Pal; Bauerfeind, Ursula; Beauvais, Romuald; Beer, Ronny; Belda, Francisco Javier; Bellander, Bo Michael; Belli, Antonio; Bellier, Remy; Benali, Habib; Benard, Thierry; Berardino, Maurizio; Beretta, Luigi; Beynon, Christopher; Bilotta, Federico; Binder, Harald; Biqiri, Erta (Peer reviewed; Journal article, 2020)
      Recent biomarker innovations hold potential for transforming diagnosis, prognostic modeling, and precision therapeutic targeting of traumatic brain injury (TBI). However, many biomarkers, including brain imaging, genomics, ...
    • Biopsychosocial predictors and trajectories of work participation after transdiagnostic occupational rehabilitation of participants with mental and somatic disorders: A cohort study 

      Hara, Karen Walseth; Bjørngaard, Johan Håkon; Jacobsen, Henrik Børsting; Borchgrevink, Petter Chr.; Johnsen, Roar; Stiles, Tore C; Brage, Søren; Woodhouse, Astrid (Journal article; Peer reviewed, 2018)
      Background Group-based transdiagnostic occupational rehabilitation programs including participants with mental and somatic disorders have emerged in clinical practice. Knowledge is sparse on subsequent participation in ...
    • Blood Speckle-Tracking Based on High–Frame Rate Ultrasound Imaging in Pediatric Cardiology 

      Nyrnes, Siri Ann; Fadnes, Solveig; Wigen, Morten Smedsrud; Mertens, Luc; Løvstakken, Lasse (Peer reviewed; Journal article, 2020)
      Background: Flow properties play an important role in cardiac function, remodeling, and morphogenesis but cannot be displayed in detail with today’s echocardiographic techniques. The authors hypothesized that blood ...
    • Bone Morphogenetic Protein 4 Gene Therapy in Mice Inhibits Myeloma Tumor Growth, But Has a Negative Impact on Bone 

      Westhrin, Marita; Holien, Toril; Zahoor, Muhammad; Moen, Siv Helen; Buene, Glenn; Størdal, Berit Fladvad; Hella, Hanne; Yuan, Huipin; de Bruijn, Joost D; Martens, Anton; Groen, Richard WJ; Bosch, Fátima; Smith, Ulf; Sponaas, Anne-Marit; Sundan, Anders; Standal, Therese (Peer reviewed; Journal article, 2020)
      Multiple myeloma is characterized by accumulation of malignant plasma cells in the bone marrow. Most patients suffer from an osteolytic bone disease, caused by increased bone degradation and reduced bone formation. Bone ...
    • C9orf72, age at onset, and ancestry help discriminate behavioral from language variants in FTLD cohorts 

      Costa, Beatrice; Manzoni, Claudia; Bernal-Quiros, Manual; Kia, Demis A.; Aguilar, Miquel; Alvarez, Ignacio; Alvarez, Victoria; Andreassen, Ole Andreas; Anfossi, Maria; Bagnoli, Silvia; Benussi, Luisa; Bernardi, Livia; Binetti, Giuliano; Blackburn, Daniel; Boada, Mercè; Borroni, Barbara; Bowns, Lucy; Bråthen, Geir; Bruni, Amalia C; Chiang, Huei-Hsin; Clarimon, Jordi; Colville, Shuna; Conidi, Maria E; Cope, Tom E; Cruchaga, Carlos; Cupidi, Chiara; Di Battista, Maria Elena; Diehl-Schmid, Janine; Diez-Fairen, Monica; Dols-Icardo, Oriol; Durante, Elisabetta; Flisar, Dusan; Frangipane, Francesca; Galimberti, Daniela; Gallo, Maura; Gallucci, Mauricio; Ghidoni, Roberta; Graff, Caroline; Grafman, Jordan H; Grossman, Murray; Hardy, John; Hernández, Isabel; Holloway, Guy J T; Huey, Edward D; Illán-Gala, Ignacio; Karydas, Anna; Khoshnood, Behzad; Kramberger, Milica G.; Kristiansen, Mark K; Sando, Sigrid Botne (Peer reviewed; Journal article, 2020)
      Objective: We sought to characterize C9orf72 expansions in relation to genetic ancestry and age at onset (AAO) and to use these measures to discriminate the behavioral from the language variant syndrome in a large pan-European ...
    • Caesarean section and the association with migraine: a retrospective register-linked HUNT population cohort study 

      Kristoffersen, Espen Saxhaug; Børte, Sigrid; Hagen, Knut; Zwart, John-Anker; Winsvold, Bendik K S (Peer reviewed; Journal article, 2020)
      Objectives To evaluate the association between caesarean section and migraine in a population-based register-linked cohort study. Setting Data from the population-based Nord-Trøndelag Health Studies (HUNT2 and HUNT3) ...
    • Calibrating and adjusting expectations in life: A grounded theory on how elderly persons with somatic health problems maintain control and balance in life and optimize well-being 

      Helvik, Anne-Sofie; Iversen, Valentina Cabral; Steiring, Randi; Hallberg, Lillemor R-M (Journal article; Peer reviewed, 2011)
      Aim: This study aims at exploring the main concern for elderly individuals with somatic health problems and what they do to manage this. Method: In total, 14 individuals (mean = 74.2 years; range = 68–86 years) of both ...
    • Can consumer grade activity devices replace research grade actiwatches in youth mental health settings? 

      Scott, Janine Linda; Grierson, Ashlee; Lillian, Gehue; Kallestad, Håvard; MacMillan, Iain; Hickie, Ian (Peer reviewed; Journal article, 2019)
      Mental health services increasingly recognize the benefits of monitoring sleep and activity patterns in youth. Objective, ecological monitoring via research grade actiwatches is valid, but an emerging literature suggests ...
    • Can we define success criteria for lumbar disc surgery? Estimates for a substantial amount of improvement in core outcome measures 

      Solberg, Tore; Johnsen, Lars Gunnar; Nygaard, Øystein Petter; Grotle, Margreth (Journal article; Peer reviewed, 2013)
      Background and purpose A successful outcome after lumbar discectomy indicates a substantial improvement. To use the cutoffs for minimal clinically important difference (MCID) as success criteria has a large potential bias, ...
    • Cancer therapy and risk of congenital malformations in children fathered by men treated for testicular germ-cell cancer: A nationwide register study 

      Al-Jebari, Yahia; Glimelius, Ingrid; Nord, Carina Berglund; Cohn-Cedermark, Gabriella; Ståhl, Olof; Tandstad, Torgrim; Jensen, Allan; Haugnes, Hege Sagstuen; Daugaard, Gedske; Rylander, Lars; Giwercman, Aleksander (Journal article; Peer reviewed, 2019)
      Background Because of the potential mutagenic effects of chemo- and radiotherapy, there is concern regarding increased risk of congenital malformations (CMs) among children of fathers with cancer. Previous register studies ...
    • Cardiac surgery does not lead to loss of oscillatory components in circulatory signals 

      Knai, Kathrine; Aadahl, Petter; Skjærvold, Nils Kristian (Peer reviewed; Journal article, 2020)
      The circulatory system is oscillatory in its nature. Oscillatory components linked to physiological processes and underlying regulatory mechanisms are identifiable in circulatory signals. Autonomic regulation is essential ...
    • Cardiorespiratory fitness in patients with rheumatoid arthritis is associated with the patient global assessment but not with objective measurements of disease activity 

      Liff, Marthe Halsan; Hoff, Mari; Fremo, Thomas; Wisløff, Ulrik; Thomas, Ranjeny; Videm, Vibeke (Journal article; Peer reviewed, 2019)
      Objective Patients with rheumatoid arthritis (RA) suffer from more cardiovascular disease (CVD), and develop cardiovascular risk factors at an earlier age than the general population. Cardiorespiratory fitness (CRF) is an ...
    • Cardiovascular disease is increased prior to onset of rheumatoid arthritis but not osteoarthritis: The population-based Nord-Trøndelag health study (HUNT) 

      Pahau, Helen; Brown, MA; Paul, S; Thomas, R; Videm, Vibeke (Journal article; Peer reviewed, 2014)
      with individuals without RA or osteoarthritis at both times (n = 33,567). Results Female gender, age, smoking, body mass index, and history of previous CV disease were associated with self-reported incident RA (previous ...
    • Centralizing a national pancreatoduodenectomy service: striking the right balance 

      Nymo, Linn Såve; Kleive, Dyre; Waardal, Kim; Bringeland, Erling Audun; Søreide, Jon Arne; Labori, Knut Jørgen; Mortensen, Kim Erlend; Søreide, Kjetil; Lassen, Kristoffer (Peer reviewed; Journal article, 2020)
      Background Centralization of pancreatic surgery is currently called for owing to superior outcomes in higher‐volume centres. Conversely, organizational and patient concerns speak for a moderation in centralization. Consensus ...
    • Cerebral cortical dimensions in headache sufferers aged 50-66 years: a population-based imaging study in the Nord-Trondelag Health Study (HUNT-MRI) 

      Husøy, Andreas Kattem; Håberg, Asta Kristine; Rimol, Lars Morten; Hagen, Knut; Vangberg, Torgil Riise; Stovner, Lars Jacob (Journal article; Peer reviewed, 2019)
      Based on previous clinic-based magnetic resonance imaging studies showing regional differences in the cerebral cortex between those with and without headache, we hypothesized that headache sufferers have a decrease in ...
    • Cerebrospinal fluid sTREM2 in Alzheimer’s disease: comparisons between clinical presentation and AT classification 

      Knapskog, Anne Brita; Henjum, Kristi; Idland, Ane-Victoria; Eldholm, Rannveig Sakshaug; Persson, Karin Ester Torun; Saltvedt, Ingvild; Watne, Leiv; Engedal, Knut; Nilsson, Lars N.G. (Peer reviewed; Journal article, 2020)
      Triggering receptor expressed on myeloid cells 2 (TREM2) is an innate immune receptor expressed by microglia. Its cleaved fragments, soluble TREM2 (sTREM2), can be measured in the cerebrospinal fluid (CSF). Previous studies ...
    • Change in Headache Suffering and Predictors of Headache after Mild Traumatic Brain Injury: A Population-Based, Controlled, Longitudinal Study with Twelve-Month Follow-Up 

      Nordhaug, Lena Hoem; Linde, Mattias; Follestad, Turid; skandsen, øystein njølstad; Bjarkø, Vera Vik; Skandsen, Toril; Vik, Anne (Journal article; Peer reviewed, 2019)
      Headache attributed to traumatic injury to the head (HAIH) is claimed to be the most common sequela following mild traumatic brain injury (MTBI), but epidemiological evidence is scarce. We explored whether patients with ...