Blar i Institutt for klinisk og molekylær medisin på tittel
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Dose to penile bulb is not associated with erectile dysfunction 18 months post radiotherapy: A secondary analysis of a randomized trial
(Journal article; Peer reviewed, 2018)Background Erectile dysfunction is a common side effect of prostate cancer (PC) therapy. In this randomized study (The RIC-study) we used patient reported outcomes to evaluate sexual function 18 months after combined ... -
Downstaging and survival after Neoadjuvant chemotherapy for bladder cancer in Norway; a population-based study
(Peer reviewed; Journal article, 2022)Background Neoadjuvant chemotherapy (NAC) before radical cystectomy is associated with pathological downstaging (DS) and improved overall survival (OS) in patients with muscle-invasive bladder cancer (MIBC). Population-based ... -
Driving Simulator Validation for Drug Impairment Research: Results from a randomized, controlled study comparing simulated and test track driving under the influence of ethanol
(Doctoral theses at NTNU;2016:304, Doctoral thesis, 2016)Kjøresimulatorer brukes blant annet til å undersøke effekten av legemidler og rusmidler på kjøreatferd og trafikkrisiko. Slik anvendelse forutsetter at testene i kjøresimulatoren virkelig måler det samme som ved kjøring ... -
Drug Combinations as a First Line of Defense against Coronaviruses and Other Emerging Viruses
(Journal article; Peer reviewed, 2021)The world was unprepared for coronavirus disease 2019 (COVID-19) and remains ill-equipped for future pandemics. While unprecedented strides have been made developing vaccines and treatments for COVID-19, there remains a ... -
Drug Combinations for Treatment of Emerging and Re-emerging Viral Infections
(Master thesis, 2022)Den pågående SARS-CoV-2 pandemien er kun en av mange virale trusler som viser at det er behov for redskap for å bekjempe kommende og gjenkommende virusinfeksjoner. Bruken av antivirale legemidler er bevist behandlingsmetode ... -
Drug information centres and their provision of decision support: The Scandinavian experience
(Peer reviewed; Journal article, 2019)What is known and objective Appraisal of drug information centres (DICs) is mainly by word of mouth communication and surveys of overall user satisfaction. Efforts to study the impact of this type of informatics and ... -
Drug modification by nurses in Norwegian nursing homes: A cross-sectional study
(Peer reviewed; Journal article, 2021)Crushing and dividing pills among older patients in nursing homes appears to be a common yet not harmless practice. Because few updates exist regarding the role of nurses and their dispensing of drugs in nursing homes, ... -
Drugs and Constipation in Elderly in Nursing Homes: What Is the Relation?
(Journal article; Peer reviewed, 2012)Introduction. Constipation is a common adverse drug reaction. Objective. Study associations between drugs and constipation in nursing home residents. Design. Cross-sectional study. Material and Methods. Nursing home residents ... -
DrugVirus.info 2.0: an integrative data portal for broad-spectrum antivirals (BSA) and BSA-containing drug combinations (BCCs)
(Peer reviewed; Journal article, 2022)Viruses can cross species barriers and cause unpredictable outbreaks in man with substantial economic and public health burdens. Broad-spectrum antivirals, (BSAs, compounds inhibiting several human viruses), and BSA-containing ... -
DTX3 copy number increase in breast cancer: a study of associations to molecular subtype, proliferation and prognosis
(Journal article; Peer reviewed, 2021)Purpose The degree of cell proliferation is important for subclassifcation of breast cancers into prognostic and therapeutic groups. DTX3 has been identifed as a driver of proliferation in luminal breast cancer. In this ... -
Dual inhibition of complement and Toll-like receptors as a novel approach to treat inflammatory diseases-C3 or C5 emerge together with CD14 as promising targets
(Journal article; Peer reviewed, 2016)The host is protected by pattern recognition systems, including complement and TLRs, which are closely cross-talking. If improperly activated, these systems might induce tissue damage and disease. Inhibition of single ... -
Duodenal inflammation in common variable immunodeficiency has altered transcriptional response to viruses
(Peer reviewed; Journal article, 2022)Background A substantial proportion of common variable immunodeficiency (CVID) patients has duodenal inflammation of largely unknown etiology. However, because of its histologic similarities with celiac disease, gluten ... -
Duration of the active phase of labor in spontaneous and induced labors
(Journal article, 2017)Introduction The aim of the study was to compare the duration of active phase of labor in women with spontaneous or induced start of labor. Material and methods An observational cohort study was performed at Stavanger ... -
Dynamics of base excision repair proteins; recruitment to replication forks and DNA lesions
(Doctoral theses at NTNU;2017:275, Doctoral thesis, 2017)DNA er arvestoffet vårt og finnes i de fleste celler i kroppen. DNA er satt sammen av to tråder bestående av sukkermolekyler, fosfat og nitrogenbaser (nukleotider). Disse kjemiske strukturene blir kontinuerlig utsatt for ... -
Dynamics of Dual Specificity Phosphatases and Their Interplay with Protein Kinases in Immune Signaling
(Journal article; Peer reviewed, 2019)Dual specificity phosphatases (DUSPs) have a well-known role as regulators of the immune response through the modulation of mitogen-activated protein kinases (MAPKs). Yet the precise interplay between the various members ... -
Dynamics of immune effector mechanisms during infection with Mycobacterium aviumin C57BL/6 mice
(Journal article; Peer reviewed, 2013)Opportunistic infections with non-tuberculous mycobacteria such as Mycobacterium avium are receiving renewed attention because of increased incidence and difficulties in treatment. As for other mycobacterial infections, a ... -
E-cadherin cleavage by MT2-MMP regulates apical junctional signaling and epithelial homeostasis in the intestine
(Journal article; Peer reviewed, 2017)Cadherin-based intercellular adhesions are essential players in epithelial homeostasis, but their dynamic regulation during tissue morphogenesis and remodeling remain largely undefined. Herein, we characterize an unexpected ... -
Early BCR-ABL1 transcript decline after 1 month of tyrosine kinase inhibitor therapy as an indicator for treatment response in chronic myeloid leukemia
(Journal article; Peer reviewed, 2017)n chronic myeloid leukemia (CML), early treatment prediction is important to identify patients with inferior overall outcomes. We examined the feasibility of using reductions in BCR-ABL1 transcript levels after 1 month of ... -
Early Childhood Growth and Risk of Adult Cerebrovascular Disease: The NFBC1966
(Journal article; Peer reviewed, 2022) -
Early discharge from hospital after birth: How Norwegian parents experience postnatal home visits by midwives – A qualitative study
(Peer reviewed; Journal article, 2021)Background: According to the WHO, the quality of care is not conditioned by the length of stay at the postnatal ward. As long as the postnatal care provided is of high quality, it could be better for the family to stay in ...