Blar i Institutt for klinisk og molekylær medisin på tittel
Viser treff 505-524 av 3590
-
Characterization of new mouse model lacking DNA repair factor MRI
(Master thesis, 2019)Double-strand breaks (DSBs) are constantly generated in the DNA by endogenous and exogenous agents. In mammalian cells, DSBs activate DNA damage responses (DDRs) to repair the lesions. One major DSB repair pathway is ... -
Characterization of protein corona on poly(alkyl cyanoacrylate) nanoparticles in human plasma
(Master thesis, 2020)Nanopartikler kan brukes som spesiallagde fremkomstmidler for forbedret medisinlevering. De kan brukes i behandling av ulike sykdommer og lidelser, inkludert kreft. Ulike materialer kan brukes i arkitekturen til nanopartiklene. ... -
Characterization of signaling pathways regulating the expression of pro-inflammatory long form thymic stromal lymphopoietin upon human metapneumovirus infection
(Journal article; Peer reviewed, 2018)Thymic stromal lymphopoietin (TSLP) is associated with several allergic diseases including asthma. Two isoforms of TSLP exist in humans, a long form (lfTSLP) and a short form (sfTSLP), displaying distinct immunological ... -
Characterization of the non-coding control region of polyomavirus KI isolated from nasopharyngeal samples from patients with respiratory symptoms or infection and from blood from healthy blood donors in Norway
(Journal article; Peer reviewed, 2016)Seroepidemiological studies showed that the human polyomavirus KI (KIPyV) is common in the human population, with age-specific seroprevalence ranging from 40–90 %. Genome epidemiological analyses demonstrated that KIPyV ... -
Characterization of the proteome and lipidome profiles of human lung cells after low dose and chronic exposure to multiwalled carbon nanotubes
(Peer reviewed; Journal article, 2018)The effects of long-term chronic exposure of human lung cells to multi-walled carbon nanotubes (MWCNT) and their impact upon cellular proteins and lipids were investigated. Since the lung is the major target organ, an in ... -
Characterization of the virulence potential of Staphylococcus condimenti isolated from a patient with severe soft tissue infection
(Journal article; Peer reviewed, 2017)The coagulase-negative bacterium Staphylococcus condimenti and closely related species are commonly isolated from or found in starter cultures of fermented sausage as well as fish and soy sauces, and have traditionally ... -
Characterization of triple negative breast cancer based on metabolic profiles using HR MAS MRS
(Master thesis, 2012)Triple negative breast cancers (TNBC) lack estrogen receptors (ER), progesterone receptors (PgR) and human epidermal growth factor receptors 2 (HER-2). Approximately 15% of breast cancer patients are diagnosed with TNBC. ... -
Characterization of Vitamin k2 FUNTIONS IN Saos-2 osteoblasts
(Master thesis, 2012)MK-7 as a potential treatment against osteoporosis, favoring bone formation, was explored in this thesis. Today most treatments for bone loss target suppression of osteoclastogenesis. Biological activity and cytotoxicity ... -
Characterizing viral diversity in Respiratory tract infection: Emphasizing on Microarray technology as genomic sensor in clinical diagnosis
(Master thesis, 2013)Background: Acute respiratory tract infection is common illness of human with significant morbidity and mortality. In pediatrics, viruses are the major cause if this illness. There is an imperative need to develop ... -
Checkpoint Inhibition in Multiple Myeloma
(Doctoral theses at NTNU;2019:107, Doctoral thesis, 2019) -
CHEK2 Mutations Affecting Kinase Activity Together With Mutations in TP53 Indicate a Functional Pathway Associated with Resistance to Epirubicin in Primary Breast Cancer
(Journal article; Peer reviewed, 2008)Background: Chemoresistance is the main obstacle to cure in most malignant diseases. Anthracyclines are among the main drugs used for breast cancer therapy and in many other malignant conditions. Single parameter analysis ... -
Chemerin is elevated in multiple myeloma patients and is expressed by stromal cells and pre-adipocytes
(Journal article; Peer reviewed, 2018)Chemerin is a recently discovered adipokine shown to be involved in both inflammatory and metabolic processes. Here, we demonstrate that chemerin serum levels are elevated in patients with multiple myeloma and that it ... -
Chemical, Physical and Biological Triggers of Evolutionary Sonserved Bcl-xL-Mediated Apoptosis
(Journal article; Peer reviewed, 2020)Background: The evidence that pan-Bcl-2 or Bcl-xL-specific inhibitors prematurely kill virus-infected or RNA/DNA-transfected cells provides rationale for investigating these apoptotic inducers further. We hypothesized that ... -
Chemotherapy for colorectal cancer - Physical exercise and quality of life
(Doctoral theses at NTNU;2024:34, Doctoral thesis, 2024)Colorectal cancer (CRC) is the third most common cancer worldwide, the second most common cancer in Norway, and the second leading cause of cancer deaths both globally and nationally. In Norway, 4745 new cases were diagnosed ... -
Chemotherapy-induced peripheral neuropathy after modern treatment of Hodgkin’s lymphoma; symptom burden and quality of life
(Peer reviewed; Journal article, 2021)Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a dose-limiting side effect of Hodgkin’s lymphoma (HL) treatment. We aimed to describe the prevalence of CIPN associated symptoms in long-term HL survivors ... -
Child Maltreatment: To Report or Not to Report? It’s More Complex than That
(Journal article; Peer reviewed, 2024)Child maltreatment (CM) is a widespread problem, contributing to health and societal difficulties often throughout the lifespan. Healthcare professionals (HCPs) who see potential warning signs for CM are responsible for ... -
Childhood Acute Lymphoblastic Leukemia: Genetic and Epigenetic Analysis of Archived Samples
(Master thesis, 2012)Acute lymphoblastic leukemia (ALL) is recognized as a fast-developing cancer originated from blood-progenitor cells. Blasts cells are immature cells which generate white blood cells (leukocytes), and it is the malignancy ... -
Childhood epilepsy and ADHD comorbidity in an Indian tertiary medical center outpatient population
(Journal article; Peer reviewed, 2018)This study aimed to assess the prevalence of Attention Deficit Hyperactivity Disorder (ADHD) and its characteristics and risk factors in children with epilepsy at a tertiary medical center in New Delhi. Children with active ... -
Children and Adolescents Surviving Cancer: Psychosocial Health, Quality of Life and Social Support
(Doktoravhandlinger ved NTNU, 1503-8181; 2011:278, Doctoral thesis, 2011)Children and Adolescents Surviving Cancer: Psychosocial Health, Quality of Life and Social Support Background: Childhood cancer involves a crisis for the child and their family where they face many challenges to achieve ...