Blar i Institutt for klinisk og molekylær medisin på tittel
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Treatment with antipsychotics in pregnancy: changes in drug disposition
(Journal article; Peer reviewed, 2017)Although pregnancy is known to cause changes in drug pharmacokinetics, little is known about its impact on serum levels of antipsychotics. In this study we retrospectively assessed 201 routine serum antipsychotic therapeutic ... -
Trends in antimicrobial resistance and empiric antibiotic therapy of bloodstream infections at a general hospital in Mid-Norway: A prospective observational study
(Journal article; Peer reviewed, 2017)Background The occurrence of bloodstream infection (BSI) and antimicrobial resistance have been increasing in many countries. We studied trends in antimicrobial resistance and empiric antibiotic therapy at a medium-sized ... -
Trends in forensic autopsy rates in Central Norway during the period 2007–2017: Can media attention impact autopsy practices?
(Peer reviewed; Journal article, 2020)The knowledge base regarding the frequency of forensic autopsies is limited. A Norwegian study investigated the practice of forensic autopsies in two neighbouring counties in Central Norway, Sør-Trøndelag and Nord-Trøndelag, ... -
Trends in mortality after a sepsis hospitalization: a nationwide prospective registry study from 2008 to 2021
(Peer reviewed; Journal article, 2023)Background Few studies have reported on mortality beyond one year after sepsis. We aim to describe trends in short- and long-term mortality among patients admitted with sepsis, and to describe the association between ... -
Trends in Prevalence and Severity of Pre/Perinatal Cerebral Palsy Among Children Born Preterm From 2004 to 2010: A SCPE Collaboration Study
(Peer reviewed; Journal article, 2021)Aim: To report on prevalence of cerebral palsy (CP), severity rates, and types of brain lesions in children born preterm 2004 to 2010 by gestational age groups. Methods: Data from 12 population-based registries of the ... -
Triage i pasientmottak for barn : en studie av validiteten av triagesystemet '' rettspediatrisk'' ved St. Olav Hospital
(Master thesis, 2016)Bakgrunn I 2012 innførte barnemottaket, St. Olavs hospital, ”Rapid Emergency Triage and Treament System-pediatric” (RETTS-p). RETTS-p er et triagesystem som har som hensikt å sortere pasientene ved ankomst med den ... -
Trisomi 21 – insidens, diagnostikk og svangerskapsavbrud 2018
(Journal article; Peer reviewed, 2021)Bakgrunn: Vi hadde som hypotese at gravide som blir undersøkt ved fostermedisinske sentre, får et annet tilbud enn gravide i resten av landet. Derfor ønsket vi å undersøke utviklingen i insidens, prenatal diagnostikk og ... -
Tumor budding score predicts lymph node status in oral tongue squamous cell carcinoma and should be included in the pathology report
(Journal article; Peer reviewed, 2020)Background The majority of oral cavity cancers arise in the oral tongue. The aim of this study was to evaluate the prognostic value of tumor budding in oral tongue squamous cell carcinoma, both as a separate variable and ... -
Tumor classification should be based on biology and not consensus: Re-defining tumors based on biology may accelerate progress, an experience of gastric cancer
(Journal article; Peer reviewed, 2021)Abstract: Malignant tumors are a consequence of genetic changes mainly occurring during cell division, sometimes with a congenital component. Therefore, accelerated cell divisions will necessarily predispose individuals, ... -
Tumor Microenvironment in Multiple Myeloma
(Doktoravhandlinger ved NTNU, 1503-8181; 2014:184, Doctoral thesis, 2014) -
The Tumor Necrosis Factor Alpha and Interleukin 6 Auto-paracrine Signaling Loop Controls Mycobacterium avium Infection via Induction of IRF1/IRG1 in Human Primary Macrophages
(Peer reviewed; Journal article, 2021)Macrophages sense and respond to pathogens by induction of antimicrobial and inflammatory programs to alert other immune cells and eliminate the infectious threat. We have previously identified the transcription factor ... -
Tumor necrosis factor inhibitors are associated with reduced complement activation in spondylarthropathies: An observational study
(Journal article; Peer reviewed, 2019)Background The complement system is involved in pathogenesis of cardiovascular disease, and might play a role in accelerated atherogenesis in spondylarthropathies (SpA). Hence, we examined complement activation in SpA, and ... -
Tumor Targeting by αvβ3-Integrin-Specific Lipid Nanoparticles Occurs via Phagocyte Hitchhiking
(Journal article; Peer reviewed, 2020)Although the first nanomedicine was clinically approved more than two decades ago, nanoparticles’ (NP) in vivo behavior is complex and the immune system’s role in their application remains elusive. At present, only ... -
Tumour size reduction after the first chemotherapy-course and outcomes of chemoradiotherapy in limited disease small-cell lung cancer
(Journal article; Peer reviewed, 2016)Objectives Concurrent chemotherapy and thoracic radiotherapy (TRT) is recommended for limited disease small-cell lung cancer (LD SCLC). TRT should start as early as possible, often meaning with the second course due to ... -
Tumour texture features from preoperative CT predict high-risk disease in endometrial cancer
(Peer reviewed; Journal article, 2020)BACKGROUND To enable more individualised treatment of endometrial cancer, improved methods for preoperative tumour characterization are warranted. Texture analysis is a method for quantification of heterogeneity in images, ... -
Tumour Vasculature in Subtypes of Breast Cancer
(Doctoral theses at NTNU;2019:35, Doctoral thesis, 2019)Breast cancer is a group of heterogeneous diseases. Using immunohistochemistry (IHC) and in situ hybridisation (ISH), they can be separated into molecular subtypes with distinct biology and prognosis. The Luminal A subtype ... -
Tuning gelatin-based hydrogel towards bioadhesive ocular tissue engineering applications
(Peer reviewed; Journal article, 2021)Gelatin based adhesives have been used in the last decades in different biomedical applications due to the excellent biocompatibility, easy processability, transparency, non-toxicity, and reasonable mechanical properties ... -
Turkish midwives’ experiences and opinions in promoting normal births: A grounded theory study
(Peer reviewed; Journal article, 2021)Introduction Worldwide, the biomedical model of maternity care has been dominant, with the overuse of interventions. Aim This study aimed to gain a deeper understanding of the experiences and opinions of Turkish ... -
Tverrfaglige legemiddelgjennomganger for kvalitetssikring av legemiddelbruk hos hjemmeboende eldre og sykehjemspasienter i Nord – Trøndelag: Effekter av læringsnettverk fra pasientsikkerhetskampanjen «I trygge hender»
(Master thesis, 2016)Bakgrunn: Riktig legemiddelbruk i sykehjem og hjemmetjenesten er to av innsatsområdene i nasjonal pasientsikkerhetskampanje «I trygge hender» (2011 – 2013). Fra desember 2013 til juni 2014 deltok kommuner i Nord – Trøndelag ... -
Twenty-nine Cases of Enterovirus-D68-associated Acute Flaccid Myelitis in Europe 2016: A Case Series and Epidemiologic Overview.
(Journal article; Peer reviewed, 2019)Background: Enterovirus-D68 (EV-D68) is a respiratory virus within the genus Enterovirus and the family of Picornaviridae. Genetically, it is closely related to rhinovirus that replicates in the respiratory tract and causes ...