Blar i Institutt for klinisk og molekylær medisin på tittel
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Molecular tools and model systems for studying inflammasome activation
(Master thesis, 2019)Upon cellular stress or invasion by pathogens such as Mycobacterium tuberculosis (Mtb), inflammasomes are activated as an innate immune response, an important host-defense mechanism to resist pathogens. Activation of NLRP3 ... -
Monitoring deep inspiration breath hold for left-sided localized breast cancer radiotherapy with an in-house developed laser distance meter system
(Journal article; Peer reviewed, 2017)Deep inspiration breath hold (DIBH) in left‐sided breast cancer radiotherapy is a technique to reduce cardiac and pulmonary doses while maintaining target coverage. This study aims at evaluating an in‐house developed DIBH ... -
Monitoring multiple myeloma by quantification of recurrent mutations in serum
(Journal article; Peer reviewed, 2017)Circulating tumor DNA is a promising biomarker to monitor tumor load and genome alterations. We explored the presence of circulating tumor DNA in multiple myeloma patients and its relation to disease activity during long-term ... -
Monitoring of the spatial and temporal dynamics of BER/SSBR pathway proteins, including MYH, UNG2, MPG, NTH1 and NEIL1-3, during DNA replication.
(Journal article; Peer reviewed, 2017)Base lesions in DNA can stall the replication machinery or induce mutations if bypassed. Consequently, lesions must be repaired before replication or in a post-replicative process to maintain genomic stability. Base excision ... -
Monitoring protein synthesis and degradation by metabolic AHA labeling and click chemistry based detection
(Master thesis, 2014)The proteome determines the biochemical reactions that can be carried out by the cell, and is thus highly dynamic and tightly regulated by protein synthesis and degradation for adaption to environmental cues and cellular ... -
Monitoring quality of care for peripheral intravenous catheters; feasibility and reliability of the peripheral intravenous catheters mini questionnaire (PIVC-miniQ)
(Journal article; Peer reviewed, 2019)Background Peripheral intravenous catheters (PIVCs) account for a mean of 38% of catheter associated bloodstream infections (CABSI) with Staphylococcus aureus, which are preventable if deficiencies in best practice are ... -
Mono- and combinational drug therapies for global viral pandemic preparedness
(Peer reviewed; Journal article, 2022)Broadly effective antiviral therapies must be developed to be ready for clinical trials, which should begin soon after the emergence of new life-threatening viruses. Here, we pave the way towards this goal by reviewing ... -
Monocyte/macrophage and T cell activation markers are not independently associated with MI risk in healthy individuals - results from the HUNT Study
(Journal article; Peer reviewed, 2017)Background We hypothesized that circulating markers reflecting monocyte/macrophage and T cell activation are associated with increased risk of myocardial infarction (MI) in apparently healthy individuals. Methods Serum ... -
Mortality among young adults born preterm and early term in 4 Nordic nations
(Peer reviewed; Journal article, 2021)Importance Adverse long-term outcomes in individuals born before full gestation are not confined to individuals born at extreme gestational ages. Little is known regarding mortality patterns among individuals born in the ... -
Mortality and neurodevelopmental outcome after invasive group B streptococcal infection in infants
(Peer reviewed; Journal article, 2023)Aim: To assess case fatality rate (CFR), infant mortality, and long-term neurodevelopmental disorders (NDDs) after invasive group B streptococcal (GBS; Streptococcus agalactiae) infection in infants. Method: Children born ... -
Mortality and Second Cancer Incidence after Treatment for Testicular Cancer: Psychosocial Health and Lifestyle Are Modifiable Prognostic Factors
(Peer reviewed; Journal article, 2022)PURPOSE To evaluate whether selected modifiable patient-reported adverse health outcomes (AHOs) in testicular cancer survivors (TCSs) represent prognostic factors of overall mortality, cancer mortality, and first-time ... -
Mortality and subsequent healthcare use among older patients discharged to a municipality with excess demand for elderly care
(Peer reviewed; Journal article, 2023)There is limited knowledge on how excess demand for elderly care influences patient outcomes. We used a natural experiment to estimate the causal effect of discharging elderly patients from hospital to municipalities with ... -
Mortality is increased in patients with rheumatoid arthritis or diabetes compared to the general population – the Nord-Trøndelag Health Study
(Peer reviewed; Journal article, 2020)Persons with rheumatoid arthritis (RA) or diabetes have increased risk of cardiovascular disease (CVD) and higher death rates compared to the general population. This study used data from the population-based Nord-Trøndelag ... -
MotifLab: a tools and data integration workbench for motif discovery and regulatory sequence analysis
(Journal article; Peer reviewed, 2013)Background: Traditional methods for computational motif discovery often suffer from poor performance. In particular, methods that search for sequence matches to known binding motifs tend to predict many non-functional ... -
Motivational Interviewing and Medication Review in Coronary Heart Disease (MIMeRiC): Intervention Development and Protocol for the Process Evaluation
(Journal article; Peer reviewed, 2018)Background: Trials of complex interventions are often criticized for being difficult to interpret because the effects of apparently similar interventions vary across studies dependent on context, targeted groups, and the ... -
Motivational interviewing and medication review in coronary heart disease (MIMeRiC): Protocol for a randomized controlled trial investigating effects on clinical outcomes, adherence and quality of life
(Journal article; Peer reviewed, 2018)Background: Preventive treatment goals for blood pressure and cholesterol levels continue to be unmet for many coronary patients. The effect of drug treatment depends on both its appropriateness and the patients’ adherence ... -
Motoriske problemer hos tenåringer født for tidlig eller for små : oversikt fra en doktorgradsavhandling
(Journal article; Peer reviewed, 2011) -
MR Evaluation of Breast Cancer Patients with a Poor Prognosis
(Doktoravhandlinger ved NTNU, 1503-8181; 2011:01, Doctoral thesis, 2011)Background and Objectives A major shift is expected in clinical cancer treatment over the next few decades as we start to move away from currently practiced, population-based approaches to more personalized medicine. One ... -
Mre11 exonuclease activity removes the chain-terminating nucleoside analog gemcitabine from the nascent strand during DNA replication
(Peer reviewed; Journal article, 2020)The Mre11 nuclease is involved in early responses to DNA damage, often mediated by its role in DNA end processing. MRE11 mutations and aberrant expression are associated with carcinogenesis and cancer treatment outcomes. ... -
MRI in the Assessment of TMJ-Arthritis in Children with JIA; Repeatability of a Newly Devised Scoring System
(Peer reviewed; Journal article, 2021)Rationale and Objectives: The temporomandibular joint (TMJ) is commonly involved in children with juvenile idiopathic arthritis. The diagnosis and evaluation of the disease progression is dependent on medical imaging. The ...