Blar i Institutt for klinisk og molekylær medisin på tittel

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    • IgG and IgG4 antibodies in subjects with irritable bowel syndrome: a case control study in the general population 

      Ligaarden, Solveig Catharina; Lydersen, Stian; Farup, Per Grønaas (Journal article; Peer reviewed, 2012)
      Background Patients with Irritable Bowel Syndrome (IBS) often relate their symptoms to the intake of food and modify their diet. IgE-mediated food allergy is uncommon in IBS, but the role of IgG-mediated food hypersensitivity ...

    • IL-32 and multiple myeloma bone disease 

      Aass, Kristin Roseth (Master thesis, 2016)
      Multiple myeloma is a malignancy of plasma cells characterized by multiple tumors in the bone marrow and progressive osteolytic bone disease. The bone lesions are caused by increased bone resorption by osteoclasts and ...

    • IL-32 is induced by activation of toll-like receptors in multiple myeloma cells 

      Aass, Kristin Roseth; Tryggestad, Synne Stokke; Mjelle, Robin; Kastnes, Martin Haugrud; Nedal, Tonje Marie Vikene; Misund, Kristine; Standal, Therese (Peer reviewed; Journal article, 2023)
      Multiple myeloma (MM) is a hematological cancer characterized by accumulation of malignant plasma cells in the bone marrow. The patients are immune suppressed and suffer from recurrent and chronic infections. Interleukin-32 ...

    • IL-6 receptor inhibition by tocilizumab attenuated expression of C5a receptor 1 and 2 in non-ST-elevation myocardial infarction 

      Orrem, Hilde Lang; Nilsson, Per; Pischke, Søren Erik; Kleveland, Ola; Yndestad, Arne; Ekholt, Karin; Damås, Jan Kristian; Espevik, Terje; Bendz, Bjørn; Halvorsen, Bente; Gregersen, Ida; Wiseth, Rune; Andersen, Geir Øystein; Ueland, Thor; Gullestad, Lars; Aukrust, Pål; Barratt-Due, Andreas; Mollnes, Tom Eirik (Journal article; Peer reviewed, 2018)
      Background: Elevated interleukin-6 (IL-6) and complement activation are associated with detrimental effects of inflammation in coronary artery disease (CAD). The complement anaphylatoxins C5a and C3a interact with their ...

    • The ileal fungal microbiota is altered in Crohn's disease and is associated with the disease course 

      Olaisen, Maya; Richard, Mathias L.; Beisvag, Vidar; Granlund, Atle van Beelen; Røyset, Elin Synnøve; Rué, Olivier; Martinsen, Tom Christian; Sandvik, Arne Kristian; Sokol, Harry; Fossmark, Reidar (Peer reviewed; Journal article, 2022)
      Introduction: Fungal microbiota's involvement in the pathogenesis of Crohn's disease (CD) is incompletely understood. The terminal ileum is a predilection site both for primary involvement and recurrences of CD. We, ...

    • Ileal Pouches 

      Wasmuth, Hans H. (Doktoravhandlinger ved NTNU, 1503-8181; 2012:10, Doctoral thesis, 2012)
      Background The conventional ileostomy can be avoided. Many attempts have been performed. The first successful solution was the continent ileostomy- Kock pouch. The high rate of complications and revisions some experienced ...

    • Illegalt eller medisinsk amfetamin – hva er inntatt 

      Frost, Joachim; Helland, Arne; Syrstad, Vigdis Elin Giæver; Aamo, Trond Oskar (Peer reviewed; Journal article, 2022)

    • Image-Guided Radiotherapy for Prostate Cancer and Side Effects after Treatment 

      Tøndel, Hanne (Doctoral theses at NTNU;2019:62, Doctoral thesis, 2019)
      Norsk sammendrag Prostatakreft er den vanligste kreftsykdommen blant norske menn med nesten 5000 nye tilfeller diagnostisert i 2016. Prognosen ved lokalisert sykdom er god og samlet 5-års overlevelse er nå godt over 90%. ...

    • The imaging of guard cells of thioglucosidase (tgg) mutants of Arabidopsis further links plant chemical defence systems with physical defence barriers 

      Ahuja, Ishita; Kissen, Ralph; Hoang, Linh; Sporsheim, Bjørnar; Halle, Kari Krizak; Wolff, Silje Aase; Ahmad, Samina Jam Nazeer; Ahmad, Jam Nazeer; Bones, Atle M. (Journal article; Peer reviewed, 2021)
      The glucosinolate-myrosinase system is a well-known plant chemical defence system. Two functional myrosinase-encoding genes, THIOGLUCOSIDASE 1 (TGG1) and THIOGLUCOSIDASE 2 (TGG2), express in aerial tissues of Arabidopsis. ...

    • Immune and inflammatory responses to freediving calculated from leukocyte gene expression profiles 

      Eftedal, Ingrid; Flatberg, Arnar; Drvis, Ivan; Dujic, Zeljko (Journal article; Peer reviewed, 2016)
      Freedivers hold their breath while diving, causing blood oxygen levels to decrease (hypoxia) while carbon dioxide increases (hypercapnia). Whereas blood gas changes are presumably involved in the progression of respiratory ...

    • Immune cell self-organization towards ongoing immune reactions on a tissue-mimicking microdevice 

      Perinetti Casoni, Giovanna (Master thesis, 2015)
      A tissue mimicking micro-device has been developed by our microfluidics group. The device has been designed in order to mimic complex in vivo scenarios of immune cell recruitment, where cells sense and are directed by ...

    • IMMUNITY-ON-A-CHIP Microfluidic Devices for Immunoengineering 

      Moura Rosa, Patrícia (Doctoral theses at NTNU;2017:357, Doctoral thesis, 2017)
      Immunitet-på-mikrobrikke Mikrofluidiske innretninger for immunologisk forskning og utvikling Sammendrag: Det siste tiåret har mikrofluidteknologi, dvs væskestrømmer i mikroskala basert på prosesser fra halvlederindustrien, ...

    • Immunization with lytic polysaccharide monooxygenase CbpD induces protective immunity against Pseudomonas aeruginosa pneumonia 

      Askarian, Fatemeh; Tsai, Chih-Ming; Cordara, Gabriele; Zurich, Raymond H.; Bjånes, Elisabet; Golten, Ole; Sørensen, Henrik Vinther; Kousha, Armin; Meier, Angela; Chikwati, Elvis Mashingaidze; Bruun, Jack-Ansgar; Ludviksen, Judith K; Choudhury, Biswa; Trieu, Desmond; Davis, Stanley; Edvardsen, Per Kristian Thorén; Mollnes, Tom Eirik; Liu, George Y.; Krengel, Ute; Conrad, Douglas J.; Vaaje-Kolstad, Gustav; Nizet, Victor (Peer reviewed; Journal article, 2023)
      Pseudomonas aeruginosa (PA) CbpD belongs to the lytic polysaccharide monooxygenases (LPMOs), a family of enzymes that cleave chitin or related polysaccharides. Here, we demonstrate a virulence role of CbpD in PA pneumonia ...

    • Immunological monitoring of newly diagnosed CML patients treated with bosutinib or imatinib first-line 

      Kreutzman, Anna; Yadav, Bhagwan; Brümmendorf, Tim H.; Gjertsen, Bjørn Tore; Lee, Moon Hee; Janssen, Jeroen; Kasanen, Tiina; Koskenvesa, Perttu; Lofti, Kourosh; Markevärn, Berit; Olsson-Strömberg, Ulla; Stentoft, Jesper; Stenke, Leif; Söderlund, Stina; Udby, Lene; Richter, Johan; Hjorth-Hansen, Henrik; Mustjoki, Satu (Peer reviewed; Journal article, 2019)
      Changes in the immune system induced by tyrosine kinase inhibitors (TKI) have been shown to positively correlate with therapy responses in chronic myeloid leukemia (CML). However, only a few longitudinal studies exist and ...

    • Immunometabolism pathways as the basis for innovative anti-viral strategies (INITIATE): A Marie Sklodowska-Curie innovative training network 

      van den Hoogen, Bernadette; Santoni, Angela; Sciume, Giuseppe; Bowie, Andrew; O'Farrelly, Cliona; O'Neill, Luke; Anthonsen, Marit Walbye; Pardali, Katerina; Young, Simon; Bergthaler, Andreas; Manel, Nicolas; Zahn, Roland; Kikkert, Marjolein; Snijder, Eric J.; van Kuppeveld, Frank; Fouchier, Ron A. M.; Hiscott, John B. (Peer reviewed; Journal article, 2020)
      The past century has witnessed major advances in the control of many infectious diseases, yet outbreaks and epidemics caused by (re-) emerging RNA viruses continue to pose a global threat to human health. As illustrated ...

    • Immunomodulatory effects of iron oxide nanoparticles in two human biological model systems 

      Wolf-Grosse, Susann (Doctoral theses at NTNU;2017:368, Doctoral thesis, 2017)

    • Immunoregulatory Intestinal Microbiota and COVID-19 in Patients with Type Two Diabetes: A Double-Edged Sword 

      Petakh, Pavlo; Kamyshna, Iryna; Nykyforuk, Andriy; Yao, Rouan; Imbery, John Franklin; Oksenych, Valentyn; Korda, Mykhaylo; Kamyshnyi, Aleksandr (Peer reviewed; Journal article, 2022)
      Coronavirus disease 2019, or COVID-19, is a major challenge facing scientists worldwide. Alongside the lungs, the system of organs comprising the GI tract is commonly targeted by COVID-19. The dysbiotic modulations in the ...

    • Immunoregulatory roles of chemokines and epithelium in inflammatory bowel disease - CCL20 in mucosa, human colonoids and peripheral blood mononuclear cells 

      Skovdahl, Helene Kolstad (Doctoral theses at NTNU;2020:382, Doctoral thesis, 2020)
      Inflammatory bowel diseases (IBD) are characterized by chronic inflammation in the intestinal tract, which leads to substantial cost for the individual and for society. The pathogenesis is described as an inflammation ...

    • Immunotherapy in inflammatory bowel disease: Novel and emerging treatments 

      Catalan-Serra, Ignacio; Brenna, Øystein (Peer reviewed; Journal article, 2018)
      Inflammatory bowel disease (IBD) is a chronic disabling inflammatory process that affects young individuals, with growing incidence. The etiopathogenesis of IBD remains poorly understood. A combination of genetic and ...

    • Impact of 2015 Earthquakes on a local hospital in Nepal: A Prospective Hospital-based Study 

      Giri, Samita; Risnes, Kari Ravndal; Uleberg, Oddvar; Rogne, Tormod; Shrestha, Sanu Krishna; Nygaard, Øystein Petter; Koju, Rajendra; Solligård, Erik (Journal article; Peer reviewed, 2018)
      Introduction Natural disasters pose a great challenge to the health systems and individual health facilities. In low-resource settings, disaster preparedness systems are often limited and not been well described. Two ...