Blar i Institutt for klinisk og molekylær medisin på tittel
Viser treff 1511-1530 av 3426
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Identification of the source of elevated hepatocyte growth factor levels in multiple myeloma patients
(Journal article; Peer reviewed, 2014)Background Hepatocyte growth factor (HGF) is a pleiotropic cytokine which can lead to cancer cell proliferation, migration and metastasis. In multiple myeloma (MM) patients it is an abundant component of the bone marrow. ... -
Identification of UCHL1 Binding Partners in Human Induced Pluripotent Stem Cell (hiPSC)-Derived Motor Neurons
(Master thesis, 2022)Proper protein regulation is crucial for cell function. Ubiquitin is a 76 amino acid (aa) protein functioning as a post translational modification and thereby playing a central role in protein regulation. Ubiquitin (Ub) ... -
Identification of unhealthy alcohol use by self-report and phosphatidylethanol (PEth) blood concentrations in an acute psychiatric department
(Peer reviewed; Journal article, 2022)Background The use of standard screening methods could improve the detection rate of unhealthy alcohol use in patients admitted to psychiatric acute and emergency departments. The aim of the present study was to investigate ... -
Identifying functional regulatory mutation blocks by integrating genome sequencing and transcriptome data
(Peer reviewed; Journal article, 2023)Millions of single nucleotide variants (SNVs) exist in the human genome; however, it remains challenging to identify functional SNVs associated with diseases. We propose a non-encoding SNVs analysis tool bpb3, BayesPI-BAR ... -
Identifying robust blood-based messenger RNA (mRNA) markers for potential detection of lung cancer: The Lung Cancer Biobank (NLCB) and the Nord-Trøndelag Health Study (HUNT) and Norwegian Women and Cancer Cohort (NOWAC)
(Doctoral theses at NTNU;2021:310, Doctoral thesis, 2021) -
Identifying small for gestational age preterm infants from the Finnish Medical Birth Register using eight growth charts
(Peer reviewed; Journal article, 2022) -
IFN-α with dasatinib broadens the immune repertoire in patients with chronic-phase chronic myeloid leukemia
(Peer reviewed; Journal article, 2022)In chronic myeloid leukemia (CML), combination therapies with tyrosine kinase inhibitors (TKIs) aim to improve the achievement of deep molecular remission that would allow therapy discontinuation. IFN-α is one promising ... -
IgG and IgG4 antibodies in subjects with irritable bowel syndrome: a case control study in the general population
(Journal article; Peer reviewed, 2012)Background Patients with Irritable Bowel Syndrome (IBS) often relate their symptoms to the intake of food and modify their diet. IgE-mediated food allergy is uncommon in IBS, but the role of IgG-mediated food hypersensitivity ... -
IL-32 and multiple myeloma bone disease
(Master thesis, 2016)Multiple myeloma is a malignancy of plasma cells characterized by multiple tumors in the bone marrow and progressive osteolytic bone disease. The bone lesions are caused by increased bone resorption by osteoclasts and ... -
IL-32 is induced by activation of toll-like receptors in multiple myeloma cells
(Peer reviewed; Journal article, 2023)Multiple myeloma (MM) is a hematological cancer characterized by accumulation of malignant plasma cells in the bone marrow. The patients are immune suppressed and suffer from recurrent and chronic infections. Interleukin-32 ... -
IL-6 receptor inhibition by tocilizumab attenuated expression of C5a receptor 1 and 2 in non-ST-elevation myocardial infarction
(Journal article; Peer reviewed, 2018)Background: Elevated interleukin-6 (IL-6) and complement activation are associated with detrimental effects of inflammation in coronary artery disease (CAD). The complement anaphylatoxins C5a and C3a interact with their ... -
The ileal fungal microbiota is altered in Crohn's disease and is associated with the disease course
(Peer reviewed; Journal article, 2022)Introduction: Fungal microbiota's involvement in the pathogenesis of Crohn's disease (CD) is incompletely understood. The terminal ileum is a predilection site both for primary involvement and recurrences of CD. We, ... -
Ileal Pouches
(Doktoravhandlinger ved NTNU, 1503-8181; 2012:10, Doctoral thesis, 2012)Background The conventional ileostomy can be avoided. Many attempts have been performed. The first successful solution was the continent ileostomy- Kock pouch. The high rate of complications and revisions some experienced ... -
Illegalt eller medisinsk amfetamin – hva er inntatt
(Peer reviewed; Journal article, 2022) -
Image-Guided Radiotherapy for Prostate Cancer and Side Effects after Treatment
(Doctoral theses at NTNU;2019:62, Doctoral thesis, 2019)Norsk sammendrag Prostatakreft er den vanligste kreftsykdommen blant norske menn med nesten 5000 nye tilfeller diagnostisert i 2016. Prognosen ved lokalisert sykdom er god og samlet 5-års overlevelse er nå godt over 90%. ... -
The imaging of guard cells of thioglucosidase (tgg) mutants of Arabidopsis further links plant chemical defence systems with physical defence barriers
(Journal article; Peer reviewed, 2021)The glucosinolate-myrosinase system is a well-known plant chemical defence system. Two functional myrosinase-encoding genes, THIOGLUCOSIDASE 1 (TGG1) and THIOGLUCOSIDASE 2 (TGG2), express in aerial tissues of Arabidopsis. ... -
Immune and inflammatory responses to freediving calculated from leukocyte gene expression profiles
(Journal article; Peer reviewed, 2016)Freedivers hold their breath while diving, causing blood oxygen levels to decrease (hypoxia) while carbon dioxide increases (hypercapnia). Whereas blood gas changes are presumably involved in the progression of respiratory ... -
Immune cell self-organization towards ongoing immune reactions on a tissue-mimicking microdevice
(Master thesis, 2015)A tissue mimicking micro-device has been developed by our microfluidics group. The device has been designed in order to mimic complex in vivo scenarios of immune cell recruitment, where cells sense and are directed by ... -
IMMUNITY-ON-A-CHIP Microfluidic Devices for Immunoengineering
(Doctoral theses at NTNU;2017:357, Doctoral thesis, 2017)Immunitet-på-mikrobrikke Mikrofluidiske innretninger for immunologisk forskning og utvikling Sammendrag: Det siste tiåret har mikrofluidteknologi, dvs væskestrømmer i mikroskala basert på prosesser fra halvlederindustrien, ... -
Immunization with lytic polysaccharide monooxygenase CbpD induces protective immunity against Pseudomonas aeruginosa pneumonia
(Peer reviewed; Journal article, 2023)Pseudomonas aeruginosa (PA) CbpD belongs to the lytic polysaccharide monooxygenases (LPMOs), a family of enzymes that cleave chitin or related polysaccharides. Here, we demonstrate a virulence role of CbpD in PA pneumonia ...