Blar i Institutt for klinisk og molekylær medisin på tittel
Viser treff 1037-1056 av 3426
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Erythrocyte Transfusion and Long-Term Mortality in Open Heart Surgery in Adults
(Doctoral theses at NTNU;2021:196, Doctoral thesis, 2021)Background Approximately 3,000 cases of cardiac surgery with cardiopulmonary bypass are performed each year in Norway. Cardiac surgery is performed to treat various disease of the heart, which includes ischemic, valvular, ... -
Erythropoietin (EPO)-receptor signaling induces cell death of primary myeloma cells in vitro
(Journal article; Peer reviewed, 2016)Background: Multiple myeloma is an incurable complex disease characterized by clonal proliferation of malignant plasma cells in a hypoxic bone marrow environment. Hypoxia-dependent erythropoietin (EPO)-receptor (EPOR) ... -
Escherichia coli-induced inflammatory responses are temperature-dependent in human whole blood ex vivo
(Peer reviewed; Journal article, 2023) -
ESPEN guidelines on nutrition in cancer patients
(Journal article; Peer reviewed, 2017)Cancers are among the leading causes of morbidity and mortality worldwide, and the number of new cases is expected to rise significantly over the next decades. At the same time, all types of cancer treatment, such as ... -
ESPEN practical guideline: Clinical Nutrition in cancer
(Peer reviewed; Journal article, 2021)Background This practical guideline is based on the current scientific ESPEN guidelines on nutrition in cancer patients. Methods ESPEN guidelines have been shortened and transformed into flow charts for easier use in ... -
Essential Omega-3 Fatty Acidsin Health and Disease: Association with total mortality and use of biomarkers in clinical practice
(Doktoravhandlinger ved NTNU, 1503-8181; 2014:278, Doctoral thesis, 2014) -
Essential roles of RNA cap-proximal ribose methylation in mammalian embryonic development and fertility
(Peer reviewed; Journal article, 2023)Eukaryotic RNA pol II transcripts are capped at the 5′ end by the methylated guanosine (m7G) moiety. In higher eukaryotes, CMTR1 and CMTR2 catalyze cap-proximal ribose methylations on the first (cap1) and second (cap2) ... -
Established and novel methods and biomarkers in breast cancer
(Doctoral theses at NTNU;2024:80, Doctoral thesis, 2024)The present thesis is based on three published papers. The work arises from three cohorts of women from Trøndelag county in Norway. These were women born between 1886 and 1977, that were diagnosed with breast cancer (BC). ... -
Establishing a real-time PCR method for analysis of stx2 expression
(Master thesis, 2013)STEC (Shiga toxin-producing E.coli) are important human pathogens, which can potentially cause hemolytic uremic syndrome (HUS). An important predictor of serious disease is the production of the variant Shiga toxin 2 (Stx2). ... -
Establishing Methodology and Best Practices for Metagenomic and Metatranscriptomic Study of the Human Gut Microbiome
(Master thesis, 2022)Due to its fundamental impact on overall health, the gut microbiome has emerged as one of the most popular research subjects over the last decade. It is believed that there are associations between gut microbial perturbation ... -
Establishing Serum Reference Ranges for Antihypertensive Drugs
(Peer reviewed; Journal article, 2020)Background: Therapeutic drug monitoring (TDM) involves the measurement of serum drug concentrations to optimize pharmacotherapy. Traditionally, blood pressure measurements alone, and not TDM, have been used to evaluate ... -
Establishing the representativeness of available surface water scenarios for plant protection products in environmental risk assessment Opinion of the Panel on Plant protection Products of the Norwegian Scientific Committee for Food and Environment (VKM)in Norway -
(Peer reviewed; Journal article, 2021) -
Establishing tools to study the involvement of Keap1 in inflammatory signaling upon infection with M. avium
(Master thesis, 2015)Mycobacterium avium is a non-tuberculous mycobacteria that causes opportunistic infections in immunocompromised individuals such as AIDS patients. The pathogen is receiving more attention due to increasing resistance ... -
Establishment of a patient-derived xenograft model of colorectal cancer in CIEA NOG mice and exploring smartfish liquid diet as a source of omega-3 fatty acids
(Peer reviewed; Journal article, 2021)Cancer patient-derived xenografts (PDXs) better preserve tumor characteristics and microenvironment than traditional cancer cell line derived xenografts and are becoming a valuable model in translational cancer research ... -
Establishment of an image analysis and acquisition platform used to test host-directed therapy in Mycobacterium avium infection
(Master thesis, 2021)Bakgrunn: Mycobacterium avium er en non-tuberkuløs mykobakterie (NTM), som er nært beslektet med Mycobacterium tuberculosis, som gir NTM lungesykdom. NTM infeksjon er vanskelig å behandle og krever en behandling med flere ... -
Establishment of an in vivo rat model for chronic musculoskeletal implant infection
(Peer reviewed; Journal article, 2020)Background The aim of the study was to establish an experimental chronic musculoskeletal infection model in vivo characterized by (a) a small bacterial inoculum, (b) no general or local signs of infection, (c) several ... -
Establishment of methods for high throughput screening of nanoparticle toxicity in mammalian cells
(Master thesis, 2015)The use of nanomaterials is getting more extensive, both within the industrial and the medical field. The production and implementation of nanomaterials into consumer market is rapid and at such a rate that they are preceding ... -
Establishment of Multiple Myeloma Cell lines with Hepatocyte growth factor (HGF) overexpression and knockdown
(Master thesis, 2013)Multiple myeloma is the malignancy of plasma cells which causes 0.9 % of all cancer related deaths. These malignant plasma cells acquire chromosomal abnormalities and complex genetic instability. Hepatocyte growth factor ... -
Establishment of Tissue Microarray for Molecular – Genetic Subclassification of Colorectal Cancer
(Master thesis, 2011)In 30-70% of colorectal cancers colonization of the liver leads to high mortality. Most liver metastases are unresectable and recurrence level after surgery is high (50%). Identification of patients at high risk to develop ... -
Estimated cardiorespiratory fitness in relation to overall, breast and prostate cancer incidence: The Norwegian HUNT Study
(Peer reviewed; Journal article, 2022)Purpose To investigate the relationships between the estimated cardiorespiratory fitness (eCRF) and the incidence of overall, breast, and prostate cancer in a large prospective cohort study. Methods We included ...