Blar i Institutt for klinisk og molekylær medisin på tittel
Viser treff 3411-3430 av 3587
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Tumor budding score predicts lymph node status in oral tongue squamous cell carcinoma and should be included in the pathology report
(Journal article; Peer reviewed, 2020)Background The majority of oral cavity cancers arise in the oral tongue. The aim of this study was to evaluate the prognostic value of tumor budding in oral tongue squamous cell carcinoma, both as a separate variable and ... -
Tumor classification should be based on biology and not consensus: Re-defining tumors based on biology may accelerate progress, an experience of gastric cancer
(Journal article; Peer reviewed, 2021)Abstract: Malignant tumors are a consequence of genetic changes mainly occurring during cell division, sometimes with a congenital component. Therefore, accelerated cell divisions will necessarily predispose individuals, ... -
Tumor Microenvironment in Multiple Myeloma
(Doktoravhandlinger ved NTNU, 1503-8181; 2014:184, Doctoral thesis, 2014) -
The Tumor Necrosis Factor Alpha and Interleukin 6 Auto-paracrine Signaling Loop Controls Mycobacterium avium Infection via Induction of IRF1/IRG1 in Human Primary Macrophages
(Peer reviewed; Journal article, 2021)Macrophages sense and respond to pathogens by induction of antimicrobial and inflammatory programs to alert other immune cells and eliminate the infectious threat. We have previously identified the transcription factor ... -
Tumor necrosis factor inhibitors are associated with reduced complement activation in spondylarthropathies: An observational study
(Journal article; Peer reviewed, 2019)Background The complement system is involved in pathogenesis of cardiovascular disease, and might play a role in accelerated atherogenesis in spondylarthropathies (SpA). Hence, we examined complement activation in SpA, and ... -
Tumor Targeting by αvβ3-Integrin-Specific Lipid Nanoparticles Occurs via Phagocyte Hitchhiking
(Journal article; Peer reviewed, 2020)Although the first nanomedicine was clinically approved more than two decades ago, nanoparticles’ (NP) in vivo behavior is complex and the immune system’s role in their application remains elusive. At present, only ... -
Tumour size reduction after the first chemotherapy-course and outcomes of chemoradiotherapy in limited disease small-cell lung cancer
(Journal article; Peer reviewed, 2016)Objectives Concurrent chemotherapy and thoracic radiotherapy (TRT) is recommended for limited disease small-cell lung cancer (LD SCLC). TRT should start as early as possible, often meaning with the second course due to ... -
Tumour texture features from preoperative CT predict high-risk disease in endometrial cancer
(Peer reviewed; Journal article, 2020)BACKGROUND To enable more individualised treatment of endometrial cancer, improved methods for preoperative tumour characterization are warranted. Texture analysis is a method for quantification of heterogeneity in images, ... -
Tumour Vasculature in Subtypes of Breast Cancer
(Doctoral theses at NTNU;2019:35, Doctoral thesis, 2019)Breast cancer is a group of heterogeneous diseases. Using immunohistochemistry (IHC) and in situ hybridisation (ISH), they can be separated into molecular subtypes with distinct biology and prognosis. The Luminal A subtype ... -
Tuning gelatin-based hydrogel towards bioadhesive ocular tissue engineering applications
(Peer reviewed; Journal article, 2021)Gelatin based adhesives have been used in the last decades in different biomedical applications due to the excellent biocompatibility, easy processability, transparency, non-toxicity, and reasonable mechanical properties ... -
Turkish midwives’ experiences and opinions in promoting normal births: A grounded theory study
(Peer reviewed; Journal article, 2021)Introduction Worldwide, the biomedical model of maternity care has been dominant, with the overuse of interventions. Aim This study aimed to gain a deeper understanding of the experiences and opinions of Turkish ... -
Tverrfaglige legemiddelgjennomganger for kvalitetssikring av legemiddelbruk hos hjemmeboende eldre og sykehjemspasienter i Nord – Trøndelag: Effekter av læringsnettverk fra pasientsikkerhetskampanjen «I trygge hender»
(Master thesis, 2016)Bakgrunn: Riktig legemiddelbruk i sykehjem og hjemmetjenesten er to av innsatsområdene i nasjonal pasientsikkerhetskampanje «I trygge hender» (2011 – 2013). Fra desember 2013 til juni 2014 deltok kommuner i Nord – Trøndelag ... -
Twenty-nine Cases of Enterovirus-D68-associated Acute Flaccid Myelitis in Europe 2016: A Case Series and Epidemiologic Overview.
(Journal article; Peer reviewed, 2019)Background: Enterovirus-D68 (EV-D68) is a respiratory virus within the genus Enterovirus and the family of Picornaviridae. Genetically, it is closely related to rhinovirus that replicates in the respiratory tract and causes ... -
Twice-daily thoracic radiotherapy in limited stage small-cell lung cancer
(Doctoral theses at NTNU;2023:156, Doctoral thesis, 2023)Norsk sammendrag Lungekreft er den kreftformen som forårsaker flest dødsfall. Lungekreft deles inn i to hovedtyper, ikke-småcellet (NSCLC) og småcellet lungekreft (SCLC). SCLC utgjør 13-15% av tilfellene og kjennestenges ... -
Twin Births: A Descriptive Study from Bwaila Hospital, Malawi
(Master thesis, 2009) -
"Two hits - one stone" increased efficacy of cisplatin-based therapies by targeting PCNA's role in both DNA repair and cellular signaling
(Journal article; Peer reviewed, 2018)Low response rate and rapid development of resistance against commonly used chemotherapeutic regimes demand new multi-targeting anti-cancer strategies. In this study, we target the stress-related roles of the scaffold ... -
Two-year motor outcomes associated with the dose of NICU based physical therapy: The Noppi RCT
(Peer reviewed; Journal article, 2022)Background Interventions involving both the parent and the preterm infant have demonstrated lasting effects on cognitive outcomes, but motor effects are less salient. It remains unclear when to commence early intervention ... -
TXNL1-XRCC1 pathway regulates cisplatin-induced cell death and contributes to resistance in human gastric cancer
(Journal article; Peer reviewed, 2014)Cisplatin is a cytotoxic platinum compound that triggers DNA crosslinking induced cell death, and is one of the reference drugs used in the treatment of several types of human cancers including gastric cancer. However, ... -
Type 2 cytokine genes as allergic asthma risk factors after viral bronchiolitis in early childhood
(Journal article; Peer reviewed, 2023) -
Type I Interferon Induction by Neisseria gonorrhoeae: Dual Requirement of Cyclic GMP-AMP Synthase and Toll-like Receptor 4
(Journal article; Peer reviewed, 2016)The innate immune system is the first line of defense against Neisseria gonorrhoeae (GC). Exposure of cells to GC lipooligosaccharides induces a strong immune response, leading to type I interferon (IFN) production via ...