Blar i Institutt for klinisk og molekylær medisin på tittel
Viser treff 2323-2342 av 3433
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PAK1 copy number in breast cancer—Associations with proliferation and molecular subtypes
(Peer reviewed; Journal article, 2023)Introduction P21-activated kinase 1 (PAK1) is known to be overexpressed in several human tumour types, including breast cancer (BC). It is located on chromosome 11 (11q13.5-q14.1) and plays a significant role in proliferation ... -
A pan-SARS-CoV-2-specific soluble angiotensin-converting enzyme 2-albumin fusion engineered for enhanced plasma half-life and needle-free mucosal delivery
(Peer reviewed; Journal article, 2023)Immunocompromised patients often fail to raise protective vaccine-induced immunity against the global emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants. Although monoclonal antibodies have ... -
Parechovirus A in Hospitalized Children With Respiratory Tract Infections: A 10-Year-Long Study From Norway
(Peer reviewed; Journal article, 2021)Background. The role of Parechovirus A (PeV-A) in hospitalized children with respiratory tract infections (RTIs) is unclear. We studied the occurrence and impact of PeV-A over 10 years. Methods. Children from Sør-Trøndelag ... -
Parental Coping, Representations, and Interactions with Their Infants at High Risk of Cerebral Palsy
(Peer reviewed; Journal article, 2022)The aim of this study is to describe parental coping, representations, and interactions during the time of inclusion in the Small Step early intervention program for infants at high risk of cerebral palsy (CP) in Norway ... -
Parental effects from participation in an intensified multimodal programme of habilitation for children with cerebral palsy
(Journal article; Peer reviewed, 2012)Objective: To evaluate the effect on parents of participating in an intensified multimodal programme of habilitation for preschool children with cerebral palsy (CP). Methods: Thirteen pre-school children with CP, and their ... -
Parental socioeconomic status and risk of cerebral palsy in the child: evidence from two Nordic population-based cohorts
(Journal article; Peer reviewed, 2018)Background We investigated whether the risk of cerebral palsy (CP) in the child varies by parents’ socioeconomic status, in Denmark and Norway. Methods We included almost 1.3 million children born in Demark during ... -
Parenteral Nutrition in Advanced Cancer: The Healthcare Providers’ Perspective
(Peer reviewed; Journal article, 2022)Introduction The evidence base for parenteral nutrition (PN) in advanced cancer patients is limited. We studied healthcare providers’ (HCPs’) experiences with PN in cancer patients, focusing on perceived treatment benefits ... -
Parp3 promotes astrocytic differentiation through a tight regulation of Nox4-induced ROS and mTorc2 activation
(Peer reviewed; Journal article, 2020)Parp3 is a member of the Poly(ADP-ribose) polymerase (Parp) family that has been characterized for its functions in strand break repair, chromosomal rearrangements, mitotic segregation and tumor aggressiveness. Yet its ... -
Participants stories about long-term achievement 60-months after attending a Healthy Life Centre programme (the VEND-RISK study) - a qualitative study
(Peer reviewed; Journal article, 2022)Background Experiences of long-term achievement in participants attending programs for changing health habits including diet and physical activity interventions aiming for weight reduction is lacking. This study aimed to ... -
Participation in school and physical education in juvenile idiopathic arthritis in a Nordic long-term cohort study
(Journal article; Peer reviewed, 2019)Background The aim of the study was to describe school attendance and participation in physical education in school among children with juvenile idiopathic arthritis (JIA). Methods Consecutive cases of JIA from ... -
Past, present and future of zebrafish in epilepsy research
(Journal article; Peer reviewed, 2021)Animal models contribute greatly to our understanding of brain development and function as well as its dysfunction in neurological diseases. Epilepsy research is a very good example of how animal models can provide us with ... -
Pathobiology of Gastric Carcinoids and Adenocarcinomas in Rodent Models and Patients: Studies of Gastrocystoplasty, Gender-Related Factors, and Autophagy
(Doktoravhandlinger ved NTNU, 1503-8181; 2011:218, Doctoral thesis, 2011)Background: Gastric adenocarcinoma is the fourth most common cancer in the world. Among several etiological factors, gastrin hormone has been considered as a cofactor. Progenitor cells/stem cells and ECL cells are targets ... -
Pathological processes in the uterine wall decidua in preeclampsia and fetal growth restriction
(Doctoral theses at NTNU;2020:11, Doctoral thesis, 2020)Sykdomsprosesser i decidua ved svangerskapsforgiftning og føtal veksthemming Morkaken består av en maternell del som utvikles fra livmorveggen (decidua) og en føtal del som er bygget opp av fosterceller (placenta). ... -
Pathway Analysis of Skin from Psoriasis Patients after Adalimumab Treatment Reveals New Early Events in the Anti-Inflammatory Mechanism of Anti-TNF-α
(Peer reviewed; Journal article, 2016)Psoriasis is a chronic cutaneous inflammatory disease. The immunopathogenesis is a complex interplay between T cells, dendritic cells and the epidermis in which T cells and dendritic cells maintain skin inflammation. ... -
Patient characteristics and outcome in three different working models of home-based rehabilitation: a longitudinal observational study in primary health care in Norway
(Peer reviewed; Journal article, 2021)Background The organisation of health care services for older adults varies within and between countries. In Norway, primary care physiotherapy services offer home-based rehabilitation to older adults. The aim of this ... -
Patient derived colonoids as drug testing platforms-Critical importance of oxygen concentration
(Peer reviewed; Journal article, 2021)Treatment of inflammatory bowel disease (IBD) is challenging, with a series of available drugs each helping only a fraction of patients. Patients may face time-consuming drug trials while the disease is active, thus there ... -
Patient dossier: Healthcare queries over distributed resources
(Journal article; Peer reviewed, 2019)As with many other aspects of the modern world, in healthcare, the explosion of data and resources opens new opportunities for the development of added-value services. Still, a number of specific conditions on this domain ... -
Patient interpretation of the Patient-Generated Subjective Global Assessment (PG-SGA) Short Form
(Journal article; Peer reviewed, 2019)Background: The Patient-Generated Subjective Global Assessment (PG-SGA) is a patient-reported instrument for assessment of nutrition status in patients with cancer. Despite thorough validation of PG-SGA, little has been ... -
Patient participation in the clinical pathway – nurses' perceptions of adults' involvement in haemodialysis
(Journal article; Peer reviewed, 2019)Aim To develop knowledge of nurses’ perceptions of participation for patients treated with haemodialysis and their next of kin. Design A qualitative study with a hermeneutic approach. Methods The data were collected ... -
Patient participation, family involvement, and compassionate care in palliative cancer care: Health personnel and family caregiver`s experiences
(Doctoral theses at NTNU;2023:69, Doctoral thesis, 2023)Samandrag Hensikta med denne avhandlinga var å utvikle kunnskap om pasientmedverknad, familieinvolvering og “compassionate care” i dei ulike fasane av det palliative forløpet sett frå perspektiva til pårørande og ...