Blar i Institutt for klinisk og molekylær medisin på tittel
Viser treff 1951-1970 av 3554
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Long term survival and local control outcomes from single dose targeted intraoperative radiotherapy during lumpectomy (TARGIT-IORT) for early breast cancer: TARGIT-A randomised clinical trial
(Peer reviewed; Journal article, 2020)Objective To determine whether risk adapted intraoperative radiotherapy, delivered as a single dose during lumpectomy, can effectively replace postoperative whole breast external beam radiotherapy for early breast ... -
Long term trends of breast cancer incidence according to proliferation status
(Peer reviewed; Journal article, 2022)Background Long-term breast cancer incidence trends according to proliferation status are poorly described. We studied time-trends in breast cancer incidence, using mitotic count and Ki-67 as markers of proliferation. ... -
Long-term consequences of prematurity: Motor skills, mental health, health-related quality of life and white matter microstructure in young adults born preterm with very low birth weight
(Doctoral theses at NTNU;2017:207, Doctoral thesis, 2017)LANGTIDSKONSEKVENSER AV FOR TIDLIG FØDSEL Motoriske ferdigheter, psykisk helse, livskvalitet og integritet av hjernens hvite substans hos unge voksne født for tidlig med veldig lav fødselsvekt Barn som er født for ... -
Long-Term Exposure to Nanosized TiO2 Triggers Stress Responses and Cell Death Pathways in Pulmonary Epithelial Cells
(Peer reviewed; Journal article, 2021)There is little in vitro data available on long-term effects of TiO2 exposure. Such data are important for improving the understanding of underlying mechanisms of adverse health effects of TiO2 . Here, we exposed pulmonary ... -
Long-term follow-up of mental health, health-related quality of life and associations with motor skills in young adults born preterm with very low birth weight
(Journal article; Peer reviewed, 2016)Background: Being born with very low birth weight(VLBW:≤1500 g) is related to long-term disability and neurodevelopmental problems, possibly affecting mental health and health-related quality of life (HRQoL). However, ... -
Long-Term Incidence of Venous Thromboembolism in Cancer: The Scandinavian Thrombosis and Cancer Cohort
(Journal article; Peer reviewed, 2018)The risk of venous thromboembolism (VTE) in patients who survive the first years after a cancer diagnosis after the acute effects of disease and treatment in comparison to a similar background population has been sparsely ... -
Long-term motor outcomes of very preterm and/or very low birth weight individuals without cerebral palsy: A review of the current evidence
(Peer reviewed; Journal article, 2020)We reviewed literature on long-term motor outcomes of individuals aged five years or older born very preterm (VP: ≤32 weeks of gestation) or with very low birth weight (VLBW: ≤1500g), without cerebral palsy (CP). PubMed ... -
Long-term outcomes in juvenile idiopathic arthritis: 18 years of follow-up in the population-based Nordic Juvenile Idiopathic Arthritis (JIA) cohort.
(Journal article; Peer reviewed, 2019)Objectives This study assessed the long‐term course, remission rate and disease burden in juvenile idiopathic arthritis (JIA) 18 years after disease onset in a population‐based setting from the early biologic era. Methods A ... -
Long-term outcomes of patients treated with rituximab as second-line treatment for adult immune thrombocytopenia – Follow-up of the RITP study
(Peer reviewed; Journal article, 2020)RITP was a double‐blind randomized, 78‐week follow‐up trial in which 109 adults with immune thrombocytopenias (ITP) who failed to achieve adequate response to steroids, were randomized to receive rituximab or placebo. Here, ... -
Long-term results after surgical treatment for severe obesity
(Doctoral theses at NTNU;2020:199, Doctoral thesis, 2020)Ny kunnskap om utvikling av alvorlig fedme har erstattet oppfatningen av at av fedme er en individuell selvforskyldt tilstand med en forståelse av at fedme er en kronisk progressiv sykdom med sammensatte årsaksfaktorer. ... -
Long-term temporal trends in incidence rate and case fatality of sepsis and COVID-19-related sepsis in Norwegian hospitals, 2008-2021: a nationwide registry study
(Peer reviewed; Journal article, 2023)Objectives To estimate temporal trends in incidence rate (IR) and case fatality during a 14-year period from 2008 to 2021, and to assess possible shifts in these trends during the COVID-19 pandemic. Setting All Norwegian ... -
Long-term therapy in COPD: Any evidence of adverse effect on bone?
(Journal article; Peer reviewed, 2009)Patients with COPD have high risk for osteoporosis and fractures. Hip and vertebral fractures might impair mobility, and vertebral fractures further reduce lung function. This review discusses the evidence of bone loss due ... -
Long-term trends in colorectal cancer: incidence, localization, and presentation
(Peer reviewed; Journal article, 2020)Background The purpose of this study was to assess trends in incidence and presentation of colorectal cancer (CRC) over a period of 37 years in a stable population in Mid-Norway. Secondarily, we wanted to predict the ... -
Long-term work outcomes and the efficacy of multidisciplinary rehabilitation programs on labor force participation in cancer patients - a protocol for a longitudinal prospective cohort study
(Journal article; Peer reviewed, 2020)Background. Many cancer survivors experience late effects of cancer treatment and therefore struggle to return to work. Norway provides rehabilitation programs to increase labor force participation for cancer survivors ... -
Longer Length of First Stay in Intermittent Residential Programmes Is Associated with Larger Weight Loss at 1 and 2 Years
(Journal article; Peer reviewed, 2013)Objective: To determine if length of first stay impacts on weight loss and cardiovascular fitness, at 1 and 2 years in severely obese patients enrolled in intermittent residential programs. Methods: In a retrospective ... -
LongITools: Dynamic longitudinal exposome trajectories in cardiovascular and metabolic noncommunicable diseases
(Peer reviewed; Journal article, 2022)The current epidemics of cardiovascular and metabolic noncommunicable diseases have emerged alongside dramatic modifications in lifestyle and living environments. These correspond to changes in our “modern” postwar societies ... -
Longitudinal Associations between Exercise and Pain in the General Population - The HUNT Pain Study
(Journal article; Peer reviewed, 2013)Background: Population-based studies have reported conflicting findings on the relationship between physical activity and pain, and most studies reporting a relationship are cross sectional. Temporal relationships are ... -
Longitudinal Associations Between Persistent Post-Concussion Symptoms and Blood Biomarkers of Inflammation and CNS-Injury Following Mild Traumatic Brain Injury
(Peer reviewed; Journal article, 2023)The aim of our study was to investigate the biological underpinnings of persistent post-concussion symptoms (PPCS) at 3 months following mild traumatic brain injury (mTBI). Patients (n = 192, age 16–60 years) with mTBI, ... -
Longitudinal Changes in Circulating Metabolites and Lipoproteins After Breast Cancer Treatment
(Peer reviewed; Journal article, 2022)The multimodal treatment of breast cancer may induce long term effects on the metabolic profile and increase the risk of future cardiovascular disease. In this study, we characterized longitudinal changes in serum lipoprotein ... -
Longitudinal changes in plasma hemopexin and alpha-1-microglobulin concentrations in women with and without clinical risk factors for pre-eclampsia
(Peer reviewed; Journal article, 2019)Recent studies have shown increased concentration of fetal hemoglobin (HbF) in pre-eclamptic women. Plasma hemopexin (Hpx) and alpha-1-microglobulin (A1M) are hemoglobin scavenger proteins that protect against toxic effects ...