Browsing Institutt for klinisk og molekylær medisin by Title
Now showing items 1266-1285 of 3589
-
Fremme psykisk helse hos kvinnen i svangerskapet
(Master thesis, 2022)Tittel: Fremme psykisk helse hos kvinnen i svangerskapet. Hensikt: Å studere hvordan jordmødre kan jobbe helsefremmende mot den gravides psykiske helse i svangerskapsomsorgen. Problemstilling: Hvordan kan jordmor bidra ... -
Frequency of epilepsy and pathological EEG findings in a Norwegian sample of children with fetal alcohol spectrum disorder: Impact on cognition and adaptive functioning
(Peer reviewed; Journal article, 2023)Background Fetal alcohol spectrum disorder (FASD) comprises a combination of developmental, cognitive, and behavioral disabilities that occur in children exposed to alcohol prenatally. A higher prevalence of epilepsy ... -
Frequency of risk factors and long-term complications in a female population with previously diagnosed diabetes mellitus in rural Nepal
(Master thesis, 2017)Background: Diabetes mellitus (DM) is a noncommunicable disease causing 1.5 million deaths annually in 2012. Its global prevalence is growing dramatically, projecting to 10.4% of the adult population in 2040. Almost 75% ... -
Friedman Score in Relation to Compliance and Treatment Response in Nonsevere Obstructive Sleep Apnea
(Peer reviewed; Journal article, 2020)Nonsevere obstructive sleep apnea (OSA) is most often treated with a continuous positive airway pressure (CPAP) device or a mandibular advancement splint (MAS). However, patient compliance with these treatments is difficult ... -
Frisettingstesting av hele, delte og knuste teofyllin depottabletter- Innledende metodeutvikling med USP apparat 4 og analyse med HPLC-UV
(Master thesis, 2023)Målet i dette masterprosjektet var opprinnelig å utvikle en frigjøringstest for hele, delte og knuste teofyllin depottabletter i USP 4 apparat (flow through cell) under simulerte gastrointestinale betingelser og tilhørende ... -
From "breakthrough" to "episodic" Cancer Pain? A European Association for Palliative Care Research Network Expert Delphi Survey Toward a Common Terminology and Classification of Transient Cancer Pain Exacerbations
(Journal article; Peer reviewed, 2016)Context Cancer pain can appear with spikes of higher intensity. Breakthrough cancer pain (BTCP) is the most common term for the transient exacerbations of pain, but the ability of the nomenclature to capture relevant ... -
From diverging reports to differing phenotypes: Are microRNAs indicative of preeclampsia subtypes?
(Master thesis, 2013)Objective: The aim of this project was to clarify if there is an alteration in the expression profiles of five miRNAs (miR-1, miR-181a, miR-195, miR-210 and miR-584) in preeclamptic placentas versus normal placentas. Experimental ... -
Fructosamine is a useful indicator of hyperglycaemia and glucose control in clinical and epidemiological studies - Cross-sectional and longitudinal experience from the AMORIS cohort
(Journal article; Peer reviewed, 2014)Context: Fructosamine is a glycemic biomarker which may be useful for indication and control of diabetes respectively. Objective: The objective of the study was to evaluate fructosamine as an indicator of ... -
Fully Integrated Oncology and Palliative Care Services at a Local Hospital in Mid-Norway: Development and Operation of an Innovative Care Delivery Model
(Peer reviewed; Journal article, 2020)Introduction Early access to cancer palliative care is recommended. Descriptions of structures and processes of outpatient palliative care clinics operated within smaller hospitals are scarce. This paper presents the ... -
Functional Analyses of Rare Germline Missense BRCA1 Variants Located within and outside Protein Domains with Known Functions
(Peer reviewed; Journal article, 2023)The BRCA1 protein is implicated in numerous important cellular processes to prevent genomic instability and tumorigenesis, and pathogenic germline variants predispose carriers to hereditary breast and ovarian cancer (HBOC). ... -
Functional dissection of inherited non-coding variation influencing multiple myeloma risk
(Peer reviewed; Journal article, 2022)Thousands of non-coding variants have been associated with increased risk of human diseases, yet the causal variants and their mechanisms-of-action remain obscure. In an integrative study combining massively parallel ... -
Functional precision cancer medicine: drug sensitivity screening enabled by cell culture models
(Peer reviewed; Journal article, 2022)Functional precision medicine is a new, emerging area that can guide cancer treatment by capturing information from direct perturbations of tumor-derived, living cells, such as by drug sensitivity screening. Precision ... -
Functional profiling reveals altered metabolic activity in divers’ oral microbiota during commercial heliox saturation diving
(Peer reviewed; Journal article, 2021)Background: The extreme environment in saturation diving affects all life forms, including the bacteria that reside on human skin and mucosa. The oral cavity alone is home to hundreds of different bacteria. In this study, ... -
Functional properties of habenular neurons are determined by developmental stage and sequential neurogenesis
(Peer reviewed; Journal article, 2020)The developing brain undergoes drastic alterations. Here, we investigated developmental changes in the habenula, a brain region that mediates behavioral flexibility during learning, social interactions, and aversive ... -
Functional Toll-like receptors in primary first-trimester trophoblasts
(Journal article; Peer reviewed, 2014)Toll-like receptors (TLRs) are an important part of the body's danger response system and crucial for initiating inflammation in response to cellular stress, tissue damage, and infections. Proper placental development is ... -
Functionalization of a clustered TiO2 nanotubular surface with platelet derived growth factor-BB covalent modification enhances osteogenic differentiation of bone marrow mesenchymal stem cells
(Peer reviewed; Journal article, 2020)A multitude of micro- and nano-surface structures have been developed to improve the clinical performance of endosseous titanium (Ti) implants. However, most of these surface structures only simulate the topographic elements ... -
The fungal cell wall component b-1,3-glucan has an adjuvant effect on the allergic response to ovalbumin in mice
(Peer reviewed; Journal article, 2010)The polyglucose b -1,3-D-glucan is a major structural component of the cell wall of yeasts and fungi. In the present study, the adjuvant activity of b-1,3-glucan from the fungus Sclerotinia sclerotiorum (SSG) on the response ... -
Fungal products and in flammatory responses in human monocytes and epithelial cells
(Doktoravhandlinger ved NTNU, 1503-8181; 2008:238, Doctoral thesis, 2008)Muggsopp i inne miljø kan forarsake flere ulike symptomer hos mennesker som eksponeres. De vanligste reaksjonene ligner betennelsesreaksjoner i slimhinner, sarlig i ovre luftveier, men ogsa andre symptomer slik som hodepine, ... -
FunHoP analysis reveals upregulation of mitochondrial genes in prostate cancer
(Peer reviewed; Journal article, 2022)Mitochondrial activity in cancer cells has been central to cancer research since Otto Warburg first published his thesis on the topic in 1956. Although Warburg proposed that oxidative phosphorylation in the tricarboxylic ... -
FunHoP: Enhanced Visualization and Analysis of Functionally Homologous Proteins in Complex Metabolic Networks
(Journal article; Peer reviewed, 2021)Cytoscape is often used for visualization and analysis of metabolic pathways. For example, based on KEGG data, a reader for KEGG Markup Language (KGML) is used to load files into Cytoscape. However, although multiple genes ...