Blar i Institutt for klinisk og molekylær medisin på tittel
Viser treff 1263-1282 av 3436
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Gene expression studies in gastrointestinal pathophysiology and neoplasia
(Doktoravhandlinger ved NTNU, 1503-8181; 2006:89, Doctoral thesis, 2006) -
Gene Network Inference and Biochemical Assessment Delineates GPCR Pathways and CREB Targets in Small Intestinal Neuroendocrine Neoplasia
(Journal article; Peer reviewed, 2011)Small intestinal (SI) neuroendocrine tumors (NET) are increasing in incidence, however little is known about their biology. High throughput techniques such as inference of gene regulatory networks from microarray experiments ... -
Gene Ontology annotation of sequence-specific DNA binding transcription factors: setting the stage for a large-scale curation effort
(Journal article; Peer reviewed, 2013)Transcription factors control which information in a genome becomes transcribed to produce RNAs that function in the biological systems of cells and organisms. Reliable and comprehensive information about transcription ... -
The Gene Ontology resource: enriching a GOld mine
(Peer reviewed; Journal article, 2021)The Gene Ontology Consortium (GOC) provides the most comprehensive resource currently available for computable knowledge regarding the functions of genes and gene products. Here, we report the advances of the consortium ... -
Gene regulation knowledge commons: community action takes care of DNA binding transcription factors
(Journal article; Peer reviewed, 2016)A large gap remains between the amount of knowledge in scientific literature and the fraction that gets curated into standardized databases, despite many curation initiatives. Yet the availability of comprehensive knowledge ... -
The gene regulation knowledge commons: the action area of GREEKC
(Peer reviewed; Journal article, 2022)As computational modeling becomes more essential to analyze and understand biological regulatory mechanisms, governance of the many databases and knowledge bases that support this domain is crucial to guarantee reliability ... -
Gene signatures ESC, MYC and ERG-fusion are early markers of a potentially dangerous subtype of prostate cancer
(Journal article; Peer reviewed, 2014)Background Good prognostic tools for predicting disease progression in early stage prostate cancer (PCa) are still missing. Detection of molecular subtypes, for instance by using microarray gene technology, can give new ... -
General movement optimality score and general movements trajectories following early parent-administrated physiotherapy in the neonatal intensive care unit
(Peer reviewed; Journal article, 2021)Background The Prechtl General Movement Assessment (GMA) is a reliable tool for the functional assessment of the young nervous system. It is based on a global assessment of the quality of infants' movements. In addition, ... -
General principles for the risk assessment of “other substances” in food supplements and energy drinks. Report of the Panel on Food Additives, Flavourings, Processing Aids, Materials in Contact with Food and Cosmetics and the Panel on Nutrition, Dietetic Products, Novel Food and Allergy of the Norwegian Scientific Committee for Food Safety
(VKM Report;, Research report, 2015) -
Generation and Functional In Vitro Analysis of Semliki Forest Virus Vectors Encoding TNF-α and IFN-γ
(Journal article; Peer reviewed, 2017)Cytokine gene delivery by viral vectors is a promising novel strategy for cancer immunotherapy. Semliki Forest virus (SFV) has many advantages as a delivery vector, including the ability to (i) induce p53-independent killing ... -
Generation of a Mouse Model Lacking the Non-Homologous End-Joining Factor Mri/Cyren
(Journal article; Peer reviewed, 2019)Classical non-homologous end joining (NHEJ) is a molecular pathway that detects, processes, and ligates DNA double-strand breaks (DSBs) throughout the cell cycle. Mutations in several NHEJ genes result in neurological ... -
The genes controlling normal function of citrate and spermine secretion are lost in aggressive prostate cancer and prostate model systems
(Peer reviewed; Journal article, 2022)High secretion of the metabolites citrate and spermine is a unique hallmark for normal prostate epithelial cells, and is reduced in aggressive prostate cancer. However, the identity of the genes controlling this biological ... -
Genetic Aberrationsin Myeloma Cells
(Doktoravhandlinger ved NTNU, 1503-8181; 2009:83, Doctoral thesis, 2009)Genetiske avvik i myelomceller Myelomatose (beinmargskreft) er kreft i plasmacellene i beinmargen. Det er den nest vanligste hematologiske kreftformen og rammer ca 300 personer i Norge hvert år. Kun 15% av pasientene er ... -
Genetic and molecular functional characterization of variants within TNFSF13B, a positional candidate preeclampsia susceptibility gene on 13q
(Journal article; Peer reviewed, 2010)Background: Preeclampsia is a serious pregnancy complication, demonstrating a complex pattern of inheritance. The elucidation of genetic liability to preeclampsia remains a major challenge in obstetric medicine. We have ... -
Genetic and Non-genetic Factors Associated WithConstipation in Cancer Patients Receiving Opioids
(Journal article; Peer reviewed, 2015)Objectives: To examine whether the inter-individual variation in constipation among patients receiving opioids for cancer pain is associated with genetic or non-genetic factors. Methods: Cancer patients receiving ... -
Genetic biomarkers in multiple myeloma
(Doctoral theses at NTNU;2019: 223, Doctoral thesis, 2019)Multiple myeloma is a cancer of plasma cells in the bone marrow that accounts for 2 % of cancer cases globally. Improved understanding of the molecular basis of this disease has resulted in new treatment options and prolonged ... -
Genetic diversity and drug resistance pattern of Mycobacterium tuberculosis strains isolated from pulmonary tuberculosis patients in the Benishangul Gumuz region and its surroundings, Northwest Ethiopia
(Peer reviewed; Journal article, 2020)Introduction Tuberculosis (TB) remains a major global public health problem and is the leading cause of death from a single bacterium, Mycobacterium tuberculosis (MTB) complex. The emergence and spread of drug-resistant ... -
Genetic diversity of rotavirus strains circulating in Norway before and after the introduction of rotavirus vaccination in children
(Peer reviewed; Journal article, 2021)Globally, rotavirus (RV) is the leading cause of acute gastroenteritis (AGE) in young children under 5 years of age. Implementation of RV vaccination is expected to result in fewer cases of RV in the target population, but ... -
Genetic Engineering for Revealing Underlying Mechanisms of Inflammatory Bowel Diseases
(Master thesis, 2020)Inflammatorisk tarmsykdom, også kalt IBD, er en samlebetegnelse på kronisk betennelse i tarmen. IBD består i hovedsak av ulcerøs kolitt og Crohns sykdom. De underliggende årsakene er i stor grad ukjent, men både genetikk, ... -
Genetic interaction between accessory non-homologous end joining factors in B and T lymphocyte development
(Master thesis, 2020)DNA dobbeltstrengsbrudd (DSB) induseres av eksogene og endogene faktorer. Ikke-homolog endeforbindelse (NHEJ) -vei er et reparasjonssystem som omhandler DSB-er over hele cellesyklusen. NHEJ er nødvendig for V (D) J-rekombinasjon ...