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Gastrin regulated activation of proteins in the elF2α-p-ATF4 network
(Master thesis, 2013)This master's thesis is a part of a research project of The Gastroenterology Cell Biology Group investigating molecular responses to gastrin induced gene expression, with focus on how duration and intensity of gastrin ... -
Gastrin-mediated regulation of gene expression; a systems biology approach
(Doktoravhandlinger ved NTNU, 1503-8181; 2012:336, Doctoral thesis, 2012)Gastrin-regulert genuttrykk; en systembiologisk tilnærming I tillegg til å være det viktigste hormonet som kontrollerer utskillelsen av magesyre (saltsyre, HCl), er gastrin også involvert i vekstregulering av mageslimhinnen. ... -
Gastritis, Gastric Polyps and Gastric Cancer
(Peer reviewed; Journal article, 2021)Gastric cancer is still an important disease causing many deaths worldwide, although there has been a marked reduction in prevalence during the last few decades. The decline in gastric cancer prevalence is due to a reduction ... -
Gastrointestinal hormones and appetite ratings after weight loss induced by diet or bariatric surgery
(Peer reviewed; Journal article, 2023)Objective The aim of this study was to compare changes in gastrointestinal hormones and appetite ratings after a similar weight loss induced by a very low-energy diet alone or in combination with sleeve gastrectomy (SG) ... -
Gefitinib or Erlotinib as Maintenance Therapy in Patients with Advanced Stage Non-Small Cell Lung Cancer: A Systematic Review
(Journal article; Peer reviewed, 2013)Background: Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKI), gefitinib and erlotinib have been tested as maintenance therapy in patients with advanced non-small-cell lung cancer (NSCLC). The ... -
Gene expression differences between PAXgene and Tempus blood RNA tubes are highly reproducible between independent samples and biobanks
(Journal article; Peer reviewed, 2017)Background Gene expression profiling from blood is sensitive to technology choices. For example, the main blood RNA collection systems—the PAXgene and Tempus tubes—differently influence RNA expression signatures. The aim ... -
Gene expression in blood reflects smoking exposure among cancer-free women in the Norwegian Women and Cancer (NOWAC) postgenome cohort
(Journal article; Peer reviewed, 2021)Active smoking has been linked to modulated gene expression in blood. However, there is a need for a more thorough understanding of how quantitative measures of smoking exposure relate to differentially expressed genes ... -
Gene expression profile changes after short-activating RNA-mediated induction of endogenous pluripotency factors in human mesenchymal stem cells
(Journal article; Peer reviewed, 2012)It is now recognized that small noncoding RNA sequences have the ability to mediate transcriptional activation of specific target genes in human cells. Using bioinformatics analysis and functional screening, we screened ... -
Gene expression profiling of Gram-negative bacteria-induced inflammation in human whole blood: The role of complement and CD14-mediated innate immune response
(Journal article; Peer reviewed, 2015)Non-sterile pathogen-induced sepsis and sterile inflammation like in trauma or ischemia–reperfusion injury may both coincide with the life threatening systemic inflammatory response syndrome and multi-organ failure. ... -
Gene expression studies and targeted metabolomics reveal disturbed serine, methionine, and tyrosine metabolism in early hypertensive nephrosclerosis
(Journal article; Peer reviewed, 2019)Introduction Hypertensive nephrosclerosis is among the leading causes of end-stage renal disease, but its pathophysiology is poorly understood. We wanted to explore early metabolic changes using gene expression and targeted ... -
Gene expression studies in gastrointestinal pathophysiology and neoplasia
(Doktoravhandlinger ved NTNU, 1503-8181; 2006:89, Doctoral thesis, 2006) -
Gene Network Inference and Biochemical Assessment Delineates GPCR Pathways and CREB Targets in Small Intestinal Neuroendocrine Neoplasia
(Journal article; Peer reviewed, 2011)Small intestinal (SI) neuroendocrine tumors (NET) are increasing in incidence, however little is known about their biology. High throughput techniques such as inference of gene regulatory networks from microarray experiments ... -
Gene Ontology annotation of sequence-specific DNA binding transcription factors: setting the stage for a large-scale curation effort
(Journal article; Peer reviewed, 2013)Transcription factors control which information in a genome becomes transcribed to produce RNAs that function in the biological systems of cells and organisms. Reliable and comprehensive information about transcription ... -
The Gene Ontology resource: enriching a GOld mine
(Peer reviewed; Journal article, 2021)The Gene Ontology Consortium (GOC) provides the most comprehensive resource currently available for computable knowledge regarding the functions of genes and gene products. Here, we report the advances of the consortium ... -
Gene regulation knowledge commons: community action takes care of DNA binding transcription factors
(Journal article; Peer reviewed, 2016)A large gap remains between the amount of knowledge in scientific literature and the fraction that gets curated into standardized databases, despite many curation initiatives. Yet the availability of comprehensive knowledge ... -
The gene regulation knowledge commons: the action area of GREEKC
(Peer reviewed; Journal article, 2022)As computational modeling becomes more essential to analyze and understand biological regulatory mechanisms, governance of the many databases and knowledge bases that support this domain is crucial to guarantee reliability ... -
Gene signatures ESC, MYC and ERG-fusion are early markers of a potentially dangerous subtype of prostate cancer
(Journal article; Peer reviewed, 2014)Background Good prognostic tools for predicting disease progression in early stage prostate cancer (PCa) are still missing. Detection of molecular subtypes, for instance by using microarray gene technology, can give new ... -
General movement optimality score and general movements trajectories following early parent-administrated physiotherapy in the neonatal intensive care unit
(Peer reviewed; Journal article, 2021)Background The Prechtl General Movement Assessment (GMA) is a reliable tool for the functional assessment of the young nervous system. It is based on a global assessment of the quality of infants' movements. In addition, ... -
General principles for the risk assessment of “other substances” in food supplements and energy drinks. Report of the Panel on Food Additives, Flavourings, Processing Aids, Materials in Contact with Food and Cosmetics and the Panel on Nutrition, Dietetic Products, Novel Food and Allergy of the Norwegian Scientific Committee for Food Safety
(VKM Report;, Research report, 2015) -
Generation and Functional In Vitro Analysis of Semliki Forest Virus Vectors Encoding TNF-α and IFN-γ
(Journal article; Peer reviewed, 2017)Cytokine gene delivery by viral vectors is a promising novel strategy for cancer immunotherapy. Semliki Forest virus (SFV) has many advantages as a delivery vector, including the ability to (i) induce p53-independent killing ...