Blar i Institutt for klinisk og molekylær medisin på tittel
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Effect of High-Dose vs Standard-Dose Vitamin D Supplementation on Neurodevelopment of Healthy Term Infants: A Randomized Clinical Trial
(Peer reviewed; Journal article, 2021)Importance Vitamin D may be important for neurodevelopment. The optimal daily dose of vitamin D for early brain development is not known. Objectives To test whether a higher (1200 IU) vs standard (400 IU) dose of ... -
Effect of intranasal oxytocin on alcohol withdrawal syndrome: A randomized placebo-controlled double-blind clinical trial
(Peer reviewed; Journal article, 2019)Background In a pilot study, intranasal oxytocin was demonstrated to reduce the benzodiazepine dose needed to relieve withdrawal symptoms during alcohol detoxification. The aim of the present study was to compare the ... -
The effect of intranasal oxytocin on processing emotional stimuli during alcohol withdrawal: A randomized placebo-controlled double-blind clinical trial
(Peer reviewed; Journal article, 2022)Alcohol dependence is associated with difficulties in processing emotional stimuli, which can lead to interpersonal problems. The neuropeptide oxytocin has been shown to modulate the processing of emotional stimuli, however, ... -
Effect of photodynamic therapy using hexyl aminolevulinate and Amphinex – in vitro and in vivo studies
(Master thesis, 2011)Photodynamic therapy (PDT) is based on administration of photosensitizers (PS) which preferentially accumulates in tumor cells, followed by exposure of light that excites PS molecules and generation of singlet oxygen or ... -
Effect of physical exercise on muscle mass and strength in cancer patients during treatment : A systematic review
(Journal article; Peer reviewed, 2013)Cancer treatment and its side effects may cause muscle wasting. Physical exercise has the potential to increase muscle mass and strength and to improve physical function in cancer patients undergoing treatment. A systematic ... -
The effect of preoperative pelvic floor muscle training on urinary and colorectal-anal distress in women undergoing pelvic organ prolapse surgery—a randomized controlled trial
(Peer reviewed; Journal article, 2021)Introduction and hypothesis Pelvic floor muscle training (PFMT) improves urinary incontinence and mild pelvic organ prolapse (POP). We aimed to investigate the effect of preoperative PFMT on urinary and colorectal-anal ... -
The Effect of Roux-en-Y Gastric Bypass on Non-Alcoholic Fatty Liver Disease Fibrosis Assessed by FIB-4 and NFS Scores—An 11.6-Year Follow-Up Study
(Peer reviewed; Journal article, 2022)Severe obesity is a strong risk factor for non-alcoholic fatty liver disease (NAFLD). Roux-en-Y gastric bypass (RYGB) surgery effectively induces weight loss, but few studies have described the long-term effects of RYGB ... -
Effect of sensor location on continuous intraperitoneal glucose sensing in an animal model
(Journal article; Peer reviewed, 2018)In diabetes research, the development of the artificial pancreas has been a major topic since continuous glucose monitoring became available in the early 2000’s. A prerequisite for an artificial pancreas is fast and reliable ... -
Effect of Spinal Cord Burst Stimulation vs Placebo Stimulation on Disability in Patients With Chronic Radicular Pain After Lumbar Spine Surgery: A Randomized Clinical Trial
(Peer reviewed; Journal article, 2022)Importance: The use of spinal cord stimulation for chronic pain after lumbar spine surgery is increasing, yet rigorous evidence of its efficacy is lacking. Objective: To investigate the efficacy of spinal cord burst ... -
Effect of supervised exercise training during pregnancy on neonatal and maternal outcomes among overweight and obese women. Secondary analyses of the ETIP trial: A randomised controlled trial
(Journal article; Peer reviewed, 2017)Background Maternal obesity associates with complications during pregnancy and childbirth. Our aim was to investigate if exercise during pregnancy in overweight/obese women could influence birth weight or other neonatal ... -
The effect of supplementation with low doses of a cod protein hydrolysate on satiety hormones and inflammatory biomarkers in adults with metabolic syndrome: A randomized, double-blind study
(Peer reviewed; Journal article, 2020)Metabolic syndrome (MetS) is characterised by metabolic abnormalities that increase the risk of developing type 2 diabetes mellitus and cardiovascular disease. Altered levels of circulating ghrelin, several adipokines and ... -
Effect of the anticoagulant, storage time and temperature of blood samples on the concentrations of 27 multiplex assayed cytokines - Consequences for defining reference values in healthy humans
(Journal article; Peer reviewed, 2017)Cytokines are potentially useful biomarkers of sepsis and other inflammatory conditions. Many cytokines can be released by leukocytes and platelets after sampling. The sampling and processing techniques are consequently ... -
Effect of Vitamin D3 Supplementation in the First 2 Years of Life on Psychiatric Symptoms at Ages 6 to 8 Years: A Randomized Clinical Trial
(Peer reviewed; Journal article, 2023)Importance Vitamin D is associated with neurodevelopment, but causality, critical windows, and potentials for modification remain unknown. Objective To determine the impact of high-dose (1200 IU) vs standard-dose (400 ... -
Effect on mother and child of eculizumab given before caesarean section in a patient with severe antiphospholipid syndrome
(Journal article; Peer reviewed, 2017)Rationale: Antiphospholipid syndrome (APS) in pregnancy may trigger the life-threatening catastrophic antiphospholipid syndrome (CAPS). Complement activation is implicated in the pathogenesis, and inhibition of complement ... -
Effectiveness of a group-based Diabetes Prevention Education Program (DiPEP) in a population with pre-diabetes: a cluster randomised controlled trial in Nepal
(Journal article; Peer reviewed, 2023)Background Although several lifestyle intervention studies have been conducted in low/middle-income countries, there were no such studies in Nepal. Therefore, a group-based culturally tailored Diabetes Prevention Education ... -
Effectiveness of laxatives in elderly - a cross sectional study in nursing homes
(Journal article; Peer reviewed, 2011)Background Laxatives are efficient drugs, but the effectiveness has been questioned. In nursing homes, the prevalence of constipation is high and laxatives are commonly used drugs. The aims of the study were to assess the ... -
Effects of a Cod Protein Hydrolysate Supplement on Symptoms, Gut Integrity Markers and Fecal Fermentation in Patients with Irritable Bowel Syndrome
(Journal article; Peer reviewed, 2019)Peptides from fish may beneficially affect several metabolic outcomes, including gut health and inflammation. The effect of fish peptides in subjects with irritable bowel syndrome (IBS) has not previously been investigated, ... -
Effects of a fall prevention program in elderly: A pragmatic observational study in two orthopedic departments
(Journal article; Peer reviewed, 2019)Purpose: Falls are a common adverse event experienced by elderly in hospitals. This study assessed the effects of a fall prevention program on the rate of fallers, the patient safety culture, and patient-perceived ... -
Effects of Adrenaline on maternal and fetal fentanyl absorption in epidural analgesia: a randomized trial
(Journal article; Peer reviewed, 2018)Background The combination of low‐dose local anesthesia and lipophilic opioids such as fentanyl is established as a standard solution for labor epidural analgesia. Fentanyl increases efficacy, but may have negative effects ... -
Effects of age and gender on the serum levels of clozapine, olanzapine, risperidone, and quetiapine
(Journal article; Peer reviewed, 2017)Objective To investigate serum concentrations of second-generation antipsychotics in relation to age and gender in a population ranging from 18 to 100 years. Method Results from a routine therapeutic drug monitoring ...