Browsing Institutt for klinisk og molekylær medisin by Title
Now showing items 1629-1648 of 3434
-
Increased risk of ischaemic heart disease after kidney donation
(Peer reviewed; Journal article, 2021)Background Previous reports suggest increased risk of hypertension and cardiovascular mortality after kidney donation. In this study we investigate the occurrence of ischaemic heart disease and cerebrovascular disease, ... -
Increased serum levels of LIGHT/TNFSF14 in nonalcoholic fatty liver disease: Possible role in hepatic inflammation
(Journal article; Peer reviewed, 2015)Objectives: The tumor necrosis factor superfamily member 14, LIGHT (homologous to lymphotoxin, exhibits inducible expression, and competes with HSV glycoprotein D for herpes virus entry mediator (HVEM), a receptor expressed ... -
Increased triacylglycerol - Fatty acid substrate cycling in human skeletal muscle cells exposed to eicosapentaenoic acid.
(Journal article; Peer reviewed, 2018)It has previously been shown that pretreatment of differentiated human skeletal muscle cells (myotubes) with eicosapentaenoic acid (EPA) promoted increased uptake of fatty acids and increased triacylglycerol accumulation, ... -
Independent and concomitant associations of gestational diabetes and maternal obesity to perinatal outcome: A register-based study
(Peer reviewed; Journal article, 2019)Aims Gestational diabetes (GDM) is often accompanied by maternal overweight. Our aim was to evaluate the separate and concomitant effects of GDM and maternal overweight/obesity on perinatal outcomes. Methods We used ... -
Individuals at high risk for type 2 diabetes invited to a lifestyle program: characteristics of participants versus non-participants (the HUNT Study) and 24-month follow-up of participants (the VEND-RISK Study)
(Journal article; Peer reviewed, 2017)Objective Prevention of type 2 diabetes mellitus is possible through lifestyle programs, but the effect depends on the program's content, resources, and setting. Lifestyle programs are often confronted with high rates of ... -
Induction and processing of uracil in the human genome: Molecular regulation of activation-induced cytidine deaminase and uracil-DNA glycosylase
(Doktoravhandlinger ved NTNU, 1503-8181; 2013:134, Doctoral thesis, 2013) -
Induction of Inflammatory Chemokines: RANTES/CCL5, MCP-1/CCL2 and MIP-1β/CCL4 in Response to Toll-Like Receptor 2 Agonists
(Master thesis, 2012)Toll-Like Receptors (TLRs) belong to signaling class of pattern recognition receptors (PRRs) and are involved in the recognition of invariant pathogen associated molecular patterns (PAMPs), which are not found in vertebrates. ... -
Induction of labor
(Doctoral theses at NTNU;2017:115, Doctoral thesis, 2017) -
Induction of labor in breech presentations - a retrospective cohort study
(Peer reviewed; Journal article, 2021)Introduction There is limited evidence on the safety and outcome of induction of breech labor. In this study, we aimed to compare the outcomes of spontaneous and induced breech deliveries and to describe variations in ... -
Induction of labor in twin pregnancies – A retrospective cohort study
(Journal article; Peer reviewed, 2022) -
Infant Motor Assessment, Long-Term Clinical Outcome, Quantitative Cerebral MRI and Cognitive Training in Children Born Preterm with Very Low Birth Weight
(Doktoravhandlinger ved NTNU, 1503-8181; 2014:257, Doctoral thesis, 2014)The preterm birth incidence and survival rates have been increasing over the last few decades due to advances in obstetric care and neonatal treatment. Despite this, the number of preterm children that develop severe ... -
Inferring causative variants in microRNA target sites
(Journal article; Peer reviewed, 2011)MicroRNAs (miRNAs) regulate genes post transcription by pairing with messenger RNA (mRNA). Variants such as single nucleotide polymorphisms (SNPs) in miRNA regulatory regions might result in altered protein levels and ... -
Inferring regulatory networks and dynamical activities of transcription factors and miRNAs
(Doktoravhandlinger ved NTNU, 1503-8181; 2014:182, Doctoral thesis, 2014)Transcription factors (TFs) and miRNAs are fundamental regulators of gene expression. Transcription factors are proteins that regulate the process of transcribing genes in the DNA into mRNA, whereas miRNAs mainly regulate ... -
Inflammasome Activator Nigericin Induces Apoptosis in Myeloma cells
(Master thesis, 2015)Multiple myeloma (MM) is a neoplastic disorder of plasma cells. Research has shown that cytokines act as a double edged sword in tumour microenvironment to facilitate MM cell homing, survival, proliferation and pathogenesis. ... -
The inflammasome components NLRP3 and ASC act in concert with IRGM to rearrange the golgi apparatus during hepatitis C virus infection
(Peer reviewed; Journal article, 2021)Hepatitis C virus (HCV) infection triggers Golgi fragmentation through the Golgi-resident protein immunity-related GTPase M (IRGM). Here, we report the roles of NLRP3 (NOD-, LRR- and pyrin domain-containing protein 3) and ... -
Inflammation and atherosclerosis: Risk associations in the HUNT surveys
(Doktoravhandlinger ved NTNU, 1503-8181; 2012:155, Doctoral thesis, 2012) -
Inflammation and Digestive Cancer
(Journal article; Peer reviewed, 2023)Chronic inflammation is linked to carcinogenesis, particularly in the digestive organs, i.e., the stomach, colon, and liver. The mechanism of this effect has, however, only partly been focused on. In this review, we focus ... -
Inflammation and Digestive Cancer
(Peer reviewed; Journal article, 2023)Chronic inflammation is linked to carcinogenesis, particularly in the digestive organs, i.e., the stomach, colon, and liver. The mechanism of this effect has, however, only partly been focused on. In this review, we focus ... -
Inflammation and Risk Prediction of Major Complications Following Cardiac Surgery
(Doctoral thesis at NTNU;2015:224, Doctoral thesis, 2015)Background In cardiac surgery improvements in quality of care have been a major focus for several decades. Statistical models for predicting the risk of operative mortality and other adverse outcomes have been an important ... -
Inflammation by pattern recognition receptors in the uterine wall decidua and the placenta of normal and preeclamptic pregnancies
(Doctoral theses at NTNU;2020:207, Doctoral thesis, 2020)Preeclampsia is a serious inflammatory disorder characterized by hypertension and proteinuria in the second half of pregnancy. It is often associated with severe maternal and fetal complications, such as fetal growth ...