Blar i Publikasjoner fra Cristin - St. Olavs hospital på tittel

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    • Multippel erythema migrans, borrelialymfocytom og nevroborreliose hos eit barn 

      Schei, Kasper; Modalsli, Ellen Heilmann; Nag, Torbjørn (Peer reviewed; Journal article, 2023)

    • Mutational signature analysis reveals NTHL1 deficiency to cause a multi-tumor phenotype 

      Grolleman, Judith E.; de Voer, Richarda M.; Elsayed, Fadwa A.; Nielsen, Maartje; Weren, Robbert D.A.; Palles, Claire; Ligtenberg, Marjolijn J.L.; Vos, Janet R.; ten Broeke, Sanne W.; de Miranda, Noel F.C.C.; Kuiper, Renske A.; Kamping, Eveline J.; Jansen, Erik A.M.; Vink-Börger, M. Elisa; Popp, Isabell; Lang, Alois; Spier, Isabel; Hüneburg, Robert; James, Paul A.; Li, Na; Staninova, Marija; Lindsay, Helen; Cockburn, David; Spasic-Boskovic, Olivera; Clendenning, Mark; Sweet, Kevin; Capellá, Gabriel; Sjursen, Wenche; Vetti, Hildegunn Høberg; Jongmans, Marjolijn C.; Neveling, Kornelia; van Kessel, Ad Geurts; Morreau, Hans; Hes, Frederik J.; Sijmons, Rolf H.; Schackert, Hans K.; Ruiz-Ponte, Clara; Dymerska, Dagmara; Lubiñski, Jan; Rivera, Barbara; Foulkes, William D.; Tomlinson, Ian P.; Valle, Laura; Buchanan, Daniel D.; Kenwrick, Sue; Adlard, Julian; Dimovski, Aleksandar J.; Campbell, Ian G.; Aretz, Stefan; Schindler, Detlev; van Wezel, Tom; Hoogerbrugge, Nicoline; Kuiper, Roland P. (Peer reviewed; Journal article, 2019)
      Biallelic germline mutations affecting NTHL1 predispose carriers to adenomatous polyposis and colorectal cancer, but the complete phenotype is unknown. We describe 29 individuals carrying biallelic germline NTHL1 mutations ...

    • MutT homologue 1 (MTH1) removes N6-methyl-dATP from the dNTP pool 

      Scaletti, Emma Rose; Vallin, Karl S.A.; Bräutigam, Lars; Sarno, Antonio; Berglund, Ulrika Warpman; Helleday, Thomas; Stenmark, Pål; Jemth, Ann-Sofie (Peer reviewed; Journal article, 2020)
      MutT homologue 1 (MTH1) removes oxidized nucleotides from the nucleotide pool and thereby prevents their incorporation into the genome and thereby reduces genotoxicity. We previously reported that MTH1 is an efficient ...

    • My husband is not ill; He has memory loss - Caregivers perspectives on health care services for persons with dementia 

      Granbo, Randi; Boulton, Elisabeth; Saltvedt, Ingvild; Helbostad, Jorunn L.; Taraldsen, Kristin (Journal article; Peer reviewed, 2019)
      Background To explore informal caregivers’ perspectives and perceived needs related to health care services/activities for older adults with dementia, in order to understand barriers and facilitators to participation. The ...

    • Mycotic abdominal aortic aneurysm caused by Borrelia afzelii: a case report 

      Torsteinsen, Magne; Nilsen, Hans-Johnny; Damås, Jan Kristian; Stensvåg, Dordi; Nyrønning, Linn Ålstedt; Bergh, Kåre (Peer reviewed; Journal article, 2022)
      Background Inflammatory aneurysms and mycotic aneurysms make up a minority of abdominal aortic aneurysms. Mainly autoimmune mechanisms are proposed in the pathogenesis of inflammatory aneurysms, and it is not routine ...

    • Myeloma-derived extracellular vesicles mediate HGF/c-Met signaling in osteoblast-like cells 

      Strømme, Olaf; Psonka Antonczyk, Katarzyna Maria; Stokke, Bjørn Torger; Sundan, Anders; Arum, Carl-Jørgen; Brede, Gaute (Journal article; Peer reviewed, 2019)
      Multiple myeloma is an incurable cancer of antibody-producing plasma cells. Hepatocyte growth factor (HGF), a cytokine aberrantly expressed in half of myeloma patients, is involved in myeloma pathogenesis by enhancing ...

    • Nanobody-directed targeting of optogenetic tools to study signaling in the primary cilium 

      Hansen, Jan; Kaiser, Fabian; Klausen, Christina; Stüven, Birthe; Chong, Raymond; Bönigk, Wolfgang; Mick, David; Möglich, Andreas; Jurisch-Yaksi, Nathalie; Schmidt, Florian; Wachten, Dagmar (Peer reviewed; Journal article, 2020)
      Compartmentalization of cellular signaling forms the molecular basis of cellular behavior. The primary cilium constitutes a subcellular compartment that orchestrates signal transduction independent from the cell body. ...

    • Nasjonal anbefaling for utredning og behandling av døgnrytmelidelser 

      Bjorvatn, Bjørn; Kallestad, Håvard; Langsrud, Knut; Vedaa, Øystein; Pallesen, Ståle; Waage, Siri; Wilhelmsen-Langeland, Ane; Saxvig, Ingvild; Abeler, Karin Louise (Peer reviewed; Journal article, 2023)
      Nasjonal kompetansetjeneste for søvnsykdommer (fra 2023: Nasjonalt senter for søvnmedisin) nedsatte høsten 2022 en arbeidsgruppe for å utvikle en nasjonal anbefaling for utredning og behandling av døgnrytmelidelser. Gruppen ...

    • Nationwide, population-based observational study of the molecular epidemiology and temporal trend of carbapenemase-producing Enterobacterales in Norway, 2015 to 2021 

      Ljungquist, Oskar; Haldorsen, Bjørg; Pöntinen, Anna Kaarina; Janice, Jessin; Josefsen, Ellen Haldis; Elstrøm, Petter; Kacelnik, Oliver; Sundsfjord, Arnfinn; Samuelsen, Ørjan; Handal, Nina; Ranheim, Trond Egil; Hansen, Bent-Are; Mjøen, Andreas Fossum; Lindemann, Paul Christoffer; Nilsen, Einar; Zaragkoulias, Kyriakos; Larsen, Hege Elisabeth; Bjørnholt, Jørgen; Gammelsrud, Karianne Wiger; Jakovljev, Aleksandra; Löhr, Iren Høyland; Bredberg, Anders; Marvik, Åshild; Minge, Christina; Tofteland, Ståle; Papp, Kristina; Onken, Annette; Weme, Einar Tollaksen; Guennigsman, Brian Albert (Peer reviewed; Journal article, 2023)
      National and regional carbapenemaseproducing Enterobacterales (CPE) surveillance is essential to understand the burden of antimicrobial resistance, elucidate outbreaks, and develop infection-control or antimicrobial-treatment ...

    • The Natural Course of Chronic Pain in a General Population: Stability and Change in an Eight-Wave Longitudinal Study Over Four Years (the HUNT Pain Study). 

      Glette, Mari; Stiles, Tore C; Borchgrevink, Petter Chr.; Landmark, Tormod (Peer reviewed; Journal article, 2020)
      Epidemiological studies have to a little extent addressed the potential fluctuations of chronic pain over time, and there is a lack of information about the long-term course of pain using repeated measurements. We wanted ...

    • Needs assessment of resuscitative endovascular balloon occlusion of the aorta (REBOA) in patients with major haemorrhage: A cross-sectional study 

      Godø, Bård Neuenkirchen; Brede, Jostein Rodseth; Krüger, Andreas Jorstad (Peer reviewed; Journal article, 2021)
      Background Resuscitative endovascular balloon occlusion of the aorta (REBOA) can be used as an adjunct treatment in traumatic abdominopelvic haemorrhage, ruptured abdominal aortic aneurysms, postpartum haemorrhage (PPH), ...

    • NEFA Dynamics in Adults With Severe Obesity and Insulin Resistance: No Coupling to the rs9939609 FTO Risk Allele 

      Mostad, Ingrid Løvold; Grill, Valdemar Erik Robert (Peer reviewed; Journal article, 2023)
      Context: The FTO gene is highly expressed in adipose tissues; however, whether nonesterified fatty acids (NEFA) dynamics are impacted by FTO has not been rigorously tested for in a uniformly obese study population comprising ...

    • Negotiating scientific knowledge in the development of an eHealth MOOC 

      Gilstad, Heidi; Skogen, Martha Rice; Toussaint, Pieter Jelle; Larsen, Cathrin Brøndbo; Faxvaag, Arild (Peer reviewed; Journal article, 2022)
      Interdisciplinary team communication in eHealth development is challenging because all disciplines have unique, intrinsic discursive practices, theories and artefacts. Due to these factors, members of interdisciplinary ...

    • NEIL1 and NEIL2 DNA glycosylases modulate anxiety and learning in a cooperative manner in mice 

      Hildrestrand, Gunn Annette; Rolseth, Veslemøy; Kunath, Nicolas; Suganthan, Rajikala; Jensen, Vidar; Bugaj, Anna Maria; Fernandez Berrocal, Marion Silvana; SIkko, Sunniva Bøe; Vetlesen, Susanne; Kusnierczyk, Anna; Olsen, Ann-Karin Hardie; Gutzkow, Kristine Bjerve; Rowe, Alexander D.; Wang, Wei; Moldestad, Olve; Syrstad, Monika; Slupphaug, Geir; Eide, Lars; Klungland, Arne; Sætrom, Pål; Luna, Luisa; Ye, Jing; Scheffler, Katja; Bjørås, Magnar (Peer reviewed; Journal article, 2021)
      Oxidative DNA damage in the brain has been implicated in neurodegeneration and cognitive decline. DNA glycosylases initiate base excision repair (BER), the main pathway for oxidative DNA base lesion repair. NEIL1 and NEIL3 ...

    • Neoadjuvant Chemoradiotherapy and Surgery for Esophageal Squamous Cell Carcinoma Versus Definitive Chemoradiotherapy With Salvage Surgery as Needed: The Study Protocol for the Randomized Controlled NEEDS Trial 

      Nilsson, Magnus; Olafsdottir, Halla; Alexandersson von Döbeln, Gabriella; Villegas, Fernanda; Gagliardi, Giovanna; Hellström, Mats; Wang, Qiao-Li; Johansson, Hemming; Gebski, Val; Hedberg, Jakob; Klevebro, Fredrik; Markar, Sheraz; Smyth, Elizabeth; Lagergren, Pernilla; Al-Haidari, Ghazwan Ahmed Dhia Eldin; Rekstad, Lars Cato; Aahlin, Eirik Kjus; Wallner, Bengt; Edholm, David; Johansson, Jan; Szabo, Eva; Reynolds, John V.; Pramesh, C.S.; Mummudi, Naveen; Joshi, Amit; Ferri, Lorenzo; Wong, Rebecca KS; O’Callaghan, Chris; Lukovic, Jelena; Chan, Kelvin KW; Leong, Trevor; Barbour, Andrew; Smithers, Mark; Li, Yin; Kang, Xiaozheng; Kong, Feng-Ming; Chao, Yin-Kai; Crosby, Tom; Bruns, Christiane; van Laarhoven, Hanneke; van Berge Henegouwen, Mark; van Hillegersberg, Richard; Rosati, Riccardo; Piessen, Guillaume; de Manzoni, Giovanni; Lordick, Florian (Peer reviewed; Journal article, 2022)
      Background: The globally dominant treatment with curative intent for locally advanced esophageal squamous cell carcinoma (ESCC) is neoadjuvant chemoradiotherapy (nCRT) with subsequent esophagectomy. This multimodal treatment ...

    • Neoadjuvant chemotherapy versus neoadjuvant chemoradiotherapy for cancer of the esophagus or gastroesophageal junction: long-term results of a randomized clinical trial 

      von Döbeln, Gabriella Alexandersson; Klevebro, Fredrik; Jacobsen, Anne-Birgitte; Johannessen, Hans Olaf; Nielsen, Niels Hilmer; Johnsen, Gjermund; Hatlevoll, Ingunn; Glenjen, Nils; Friesland, Signe; Lundell, Lars R.; Yu, Jingru; Nilsson, Magnus (Peer reviewed; Journal article, 2019)
      NeoRes I is a randomized phase II trial comparing neoadjuvant chemoradiotherapy with neoadjuvant chemotherapy in the treatment of resectable cancer of the esophagus or gastroesophageal junction. Patients with biopsy-proven ...

    • NeoDoppler: New ultrasound technology for continous cerebral circulation monitoring in neonates. 

      Vik, Sigrid Dannheim; Torp, Hans; Follestad, Turid; Støen, Ragnhild; Nyrnes, Siri Ann (Journal article; Peer reviewed, 2019)
      BACKGROUND: There is a strong need for continuous cerebral circulation monitoring in neonatal care, since suboptimal cerebral blood flow may lead to brain injuries in preterm infants and other critically ill neonates. ...

    • Neopterin and kynurenic acid as predictors of stroke recurrence and mortality: a multicentre prospective cohort study on biomarkers of inflammation measured three months after ischemic stroke 

      Alme, Katinka Nordheim; Ulvik, Arve; Askim, Torunn; Assmus, Jörg; Mollnes, Tom Eirik; Naik, Mala; Næss, Halvor; Saltvedt, Ingvild; Ueland, Per-Magne; Knapskog, Anne Brita (Peer reviewed; Journal article, 2021)
      Background Chronic low-grade inflammation is associated with both ischemic stroke and sedentary behaviour. The aim of this study was to investigate the predictive abilities of biomarkers of inflammation and immune modulation ...

    • Neurocognitive Outcome and Compensating Possibilities in Children and Adolescents Treated for Acute Lymphoblastic Leukemia With Chemotherapy Only 

      Lofstad, Grete Elisabeth; Reinfjell, Trude; Weider, Siri; Diseth, Trond H; Hestad, Knut (Journal article; Peer reviewed, 2019)
      Aim: To examine the neurocognitive outcomes in children and adolescents with acute lymphoblastic leukemia (ALL) in remission who were treated with systemic chemotherapy only (CTO). Methods: Neurocognitive performances ...

    • Neuromodulatory effect of NLRP3 and ASC in neonatal hypoxic ischemic encephalopathy 

      Ystgaard, Martin Bogale; Scheffler, Katja; Suganthan, Rajikala; Bjørås, Magnar; Ranheim, Trine; Sagen, Ellen Lund; Halvorsen, Bente; Saugstad, Ola Didrik; Yndestad, Arne (Journal article; Peer reviewed, 2019)
      Background: Following birth asphyxia there is a robust inflammatory response. NLRP3 is a receptor of the innate immune system. Upon activation, NLRP3 forms an inflammasome together with ASC and procaspase-1 to mediate ...