Browsing Publikasjoner fra Cristin - St. Olavs hospital by Title

Now showing items 857-876 of 1465

    • Metacognitive Therapy for Emotional Distress in Adult Cancer Survivors: A Case Series 

      Fisher, Peter Leonard; Byrne, Angela; Salmon, Peter (Peer reviewed; Journal article, 2017)
      Many adult cancer survivors experience persistent emotional distress after completing cancer treatment. The aim of this study was to test the potential of a brief transdiagnostic psychological intervention—metacognitive ...

    • Metformin in Pregnancy Study (MiPS): protocol for a systematic review with individual patient data meta-analysis 

      Mousa, Aya; Løvvik, Tone Shetelig; Ijas, Hilkka; Carlsen, Sven Magnus; Morin-Papunen, Laure; Tertti, Kristiina; Rönnema, Tapani; Syngelaki, Argyro; Nicolaides, Kypros; Shehata, Hassan; Burden, Chirsty; Rowan, Janet; Norman, Jane E.; Dodd, Jodie M.; Hague, William; Vanky, Eszter; Teede, Helena J. (Peer reviewed; Journal article, 2020)
      Introduction: Gestational diabetes mellitus (GDM) is a common disorder of pregnancy and contributes to adverse pregnancy outcomes. Metformin is often used for the prevention and management of GDM; however, its use in ...

    • MGMT Promoter Methylation Status Is Not Related to Histological or Radiological Features in IDH Wild-type Glioblastomas 

      Mikkelsen, Vilde Elisabeth; Hong, Yan Dai; Stensjøen, Anne Line; Berntsen, Erik Magnus; Salvesen, Øyvind; Solheim, Ole; Torp, Sverre Helge (Peer reviewed; Journal article, 2020)
      O6-methylguanine DNA methyltransferase (MGMT) promoter methylation is an important favorable predictive marker in patients with glioblastoma (GBM). We hypothesized that MGMT status could be a surrogate marker of pretreatment ...

    • Microglia and macrophages in human glioblastomas: A morphological and immunohistochemical study 

      Kvisten, Magnus; Mikkelsen, Vilde Elisabeth; Stensjøen, Anne Line; Solheim, Ole; van der Want, Johannes Jacobus Leendert; Torp, Sverre Helge (Journal article; Peer reviewed, 2019)
      Glioblastomas (GBMs), a type of highly malignant brain tumour, contain various macrophages/microglia that are known as tumour‑associated macrophages (TAMs). These TAMs have various roles in tumour biology. Histopathological ...

    • MicroRNA profiling of psoriatic skin identifies 11 miRNAs associated with disease severity 

      Solvin, Åshild Øksnevad; Chawla, Konika; Olsen, Lene Christin; Hegre, Siv Anita; Danielsen, Kjersti; Jenssen, Marita; Furberg, Anne-Sofie; Saunes, Marit; Hveem, Kristian; Sætrom, Pål; Løset, Mari (Peer reviewed; Journal article, 2021)
      MicroRNAs (miRNAs) are small non-coding RNAs that have emerged as central regulators of gene expression and powerful biomarkers of disease. Much is yet unknown about their role in psoriasis pathology. To globally characterize ...

    • microRNA-451a prevents activation of matrix metalloproteinases 2 and 9 in human cardiomyocytes during pathological stress stimulation. 

      Scrimgeour, Nathan Robert; Wrobel, Aleksandra Zofia; Pinho, Maria; Høydal, Morten (Peer reviewed; Journal article, 2019)
      Matrix metalloproteinases (MMP) are important for cardiac remodeling. Recently, microRNA (miR)-451a has been found to inhibit the expression of both MMP-2 and MMP-9 in human malignancies, but its role in cardiomyocytes has ...

    • A middle-out modeling strategy to extend a colon cancer logical model improves drug synergy predictions in epithelial-derived cancer cell lines 

      Tsirvouli, Eirini; Touré, Vasundra; Niederdorfer, Barbara; Vazquez Garcia, Miguel; Flobak, Åsmund; Kuiper, Martin (Peer reviewed; Journal article, 2020)
      Cancer is a heterogeneous and complex disease and one of the leading causes of death worldwide. The high tumor heterogeneity between individuals affected by the same cancer type is accompanied by distinct molecular and ...

    • Migraine and risk of stroke 

      Øie, Lise Rystad; Kurth, Tobias; Gulati, Sasha; Dodick, David W. (Peer reviewed; Journal article, 2020)
      Migraine and stroke are two common and heterogeneous neurovascular disorders responsible for a significant burden for those affected and a great economic cost for the society. There is growing evidence that migraine increases ...

    • Mild to Moderate Cognitive Impairment Does Not Affect the Ability to Self-Report Important Symptoms in Patients With Cancer: A Prospective Longitudinal Multinational Study (EPCCS) 

      Ekström, Magnus P.; Palmqvist, Sebastian; Currow, David C.; Sjøgren, Per; Kurita, Geana Paula; Jakobsen, Gunnhild; Kaasa, Stein; Hjermstad, Marianne Jensen (Peer reviewed; Journal article, 2020)
      Context Patients with advanced cancer commonly suffer from both distressing symptoms and cognitive impairment, but the effect of cognitive impairment on the reliability and validity of symptom self-report is unknown. ...

    • miR-210 Regulates Apoptotic Cell Death during Cellular Hypoxia and Reoxygenation in a Diametrically Opposite Manner 

      Marwarha, Gurdeep; Røsand, Øystein; Scrimgeour, Nathan Robert; Slagsvold, Katrine Hordnes; Høydal, Morten (Peer reviewed; Journal article, 2021)
      Apoptotic cell death of cardiomyocytes is a characteristic hallmark of ischemia–reperfusion (I/R) injury. The master hypoxamiR, microRNA-210 (miR-210), is considered the primary driver of the cellular response to hypoxic ...

    • Missing Data in Prediction Research: A Five-Step Approach for Multiple Imputation, Illustrated in the CENTER-TBI Study 

      Gravesteijn, Benjamin; Sewalt, Charlie; Venema, Esmee; Nieboer, Daan; Steyerberg, Ewout W.; Andelic, Nada; Andreassen, Lasse; Anke, Audny Gabriele Wagner; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne; Åkerlund, Cecilia; Amrein, Krisztina; Antoni, Anna; Audibert, Gerard; Azouvi, Philippe; Azzolini, Maria luisa; Bartels, Ronald; Barzo, Pal; Beauvais, Romuald; Beer, Ronny; Bellander, Bo-michael; Belli, Antonio; Benali, Habib; Berardino, Maurizio; Beretta, Luigi; Blaabjerg, Morten; Bragge, Peter; Brazinova, Alexandra; Brinck, Vibeke; Brooker, Joanne; Brorsson, Camilla; Buki, Andras; Bullinger, Monika; Cabeleira, Manuel; Caccioppola, Alessio; Calappi, Emiliana; Calvi, Maria rosa; Cameron, Peter; Lozano, Guillermo carbayo; Carbonara, Marco; Chevallard, Giorgio; Chieregato, Arturo; Citerio, Giuseppe; Cnossen, Maryse; Coburn, Mark (Peer reviewed; Journal article, 2021)
      In medical research, missing data is common. In acute diseases, such as traumatic brain injury (TBI), even well-conducted prospective studies may suffer from missing data in baseline characteristics and outcomes. Statistical ...

    • Mitochondrial C5aR1 activity in macrophages controls IL-1β production underlying sterile inflammation 

      Niyonzima, Nathalie; Rahman, Jubayer; Kunz, Natalie; West, Erin; Freiwald, Tilo; Desai, Jigar V.; Merle, Nicolas; Gidon, Alexandre; Sporsheim, Bjørnar; Lionakis, Michail S.; Evensen, Kristin; Lindberg, Beate; Skagen, Karolina; Skjelland, Mona; Singh, Parul; Haug, Markus; Ruseva, Marieta M.; Kolev, Martin; Bibby, Jack; Marshall, Olivia; O’Brien, Brett; Deeks, Nigel; Afzali, Behdad; Clark, Richard J.; Woodruff, Trent M.; Pryor, Mylton; Yang, Zhi-Hong; Remaley, Alan T.; Mollnes, Tom Eirik; Hewitt, Stephen M.; Yan, Bingyu; Kazemian, Majid; Kiss, Mate G.; Binder, Christoph J.; Halvorsen, Bente; Espevik, Terje; Kemper, Claudia (Peer reviewed; Journal article, 2021)
      While serum-circulating complement destroys invading pathogens, intracellularly active complement, termed the “complosome,” functions as a vital orchestrator of cell-metabolic events underlying T cell effector responses. ...

    • Mobile Assessments of Mood, Cognition, Smartphone-Based Sensor Activity, and Variability in Craving and Substance Use in Patients With Substance Use Disorders in Norway: Prospective Observational Feasibility Study 

      Lauvsnes, Anders Dahlen Forsmo; Hansen, Tor Ivar; Ankill, Sebastian Øiungen; Bae, Sang Won; Gråwe, Rolf W.; Braund, Taylor A.; Larsen, Mark; Langaas, Mette (Peer reviewed; Journal article, 2023)
      Background: Patients with substance use disorders (SUDs) are at increased risk for symptom deterioration following treatment, with up to 60% resuming substance use within the first year posttreatment. Substance use craving ...

    • Mobile Sensing in Substance Use Research: A Scoping Review 

      Lauvsnes, Anders Dahlen Forsmo; Langaas, Mette; Toussaint, Pieter Jelle; Gråwe, Rolf W. (Peer reviewed; Journal article, 2020)
      Background:Addictive disorders and substance use are significant health challenges worldwide, and relapse is a core component of addictive disorders. The dynamics surrounding relapse and especially the immediate period ...

    • Mode of delivery of Cognitive Behavioral Therapy for Insomnia: a randomized controlled non-inferiority trial of digital and face-to-face therapy 

      Kallestad, Håvard; Scott, Janine Linda; Vedaa, Øystein; Lydersen, Stian; Vethe, Daniel; Morken, Gunnar; Stiles, Tore C; Sivertsen, Børge; Langsrud, Knut (Peer reviewed; Journal article, 2021)
      Study Objectives Digital Cognitive Behavioral Therapy for Insomnia (dCBT-I) has demonstrated efficacy in reducing insomnia severity in self-referred and community samples. It is unknown, however, how dCBT-I compares to ...

    • Models, frameworks and theories in the implementation of programs targeted to reduce formal coercion in mental health settings: a systematic review 

      Lantta, Tella; Duxbury, Joy; Haines-Delmont, Alina; Björkdahl, Anna; Husum, Tonje Lossius; Lickiewicz, Jakub; Douzenis, Athanassios; Craig, Elaine; Goodall, Katie; Bora, Christina; Whyte, Rachel; Whittington, Richard Charles (Peer reviewed; Journal article, 2023)
      Introduction: Implementation models, frameworks and theories (hereafter tools) provide researchers and clinicians with an approach to understand the processes and mechanisms for the successful implementation of healthcare ...

    • Moderate and severe traumatic brain injury in general hospitals: a ten-year population-based retrospective cohort study in central Norway 

      Rahim, Shavin; Laugsand, Eivor Alette; Fyllingen, Even Hovig; Rao, Vidar; Pantelatos, Rabea Iris; Müller, Tomm Brostrup; Vik, Anne; Skandsen, Toril (Peer reviewed; Journal article, 2022)
      Background Patients with moderate and severe traumatic brain injury (TBI) are admitted to general hospitals (GHs) without neurosurgical services, but few studies have addressed the management of these patients. This ...

    • Modes of e-Health delivery in secondary prevention programmes for patients with coronary artery disease: A systematic review 

      Brørs, Gunhild; Pettersen, Trond Røed; Hansen, Tina B.; Fridlund, Bengt Gotthard Anton; Hølvold, Linn Benjaminsen; Lund, Hans; Norekvål, Tone M. (Peer reviewed; Journal article, 2019)
      Background: Electronic health (e-Health) interventions are emerging as an effective alternative model for improving secondary prevention of coronary artery disease (CAD). The aim of this study was to describe the effectiveness ...

    • Modified prolonged exposure therapy as Early Intervention after Rape (The EIR-study): study protocol for a multicenter randomized add-on superiority trial 

      Haugen, Tina; Halvorsen, Joar Øveraas; Friborg, Oddgeir; Simpson, Melanie Rae; Mork, Paul Jarle; Mikkelsen, Gustav; Elklit, Ask; Rothbaum, Barbara O.; Schei, Berit; Hagemann, Cecilie Therese (Peer reviewed; Journal article, 2023)
      Background Sexual assault and rape are the traumatic life events with the highest probability for posttraumatic stress disorder (PTSD), which can have devastating consequences for those afflicted by the condition. Studies ...

    • The molecular characteristics of high-grade gastroenteropancreatic neuroendocrine neoplasms 

      Venizelos, Andreas; Elvebakken, Hege; Perren, Aurel; Nikolaienko, Oleksii; Deng, Wei; Lothe, Inger Marie Bowitz; Couvelard, Anne; Hjortland, Geir Olav; Sundlöv, Anna; Svensson, Johanna; Garresori, Herish; Kersten, Christian; Hofsli, Eva; Detlefsen, Sönke; Krogh, Merete; Sørbye, Halfdan; Knappskog, Stian (Peer reviewed; Journal article, 2021)
      High-grade (HG) gastroenteropancreatic (GEP) neuroendocrine neoplasms (NEN) are rare but have a very poor prognosis and represent a severely understudied class of tumours. Molecular data for HG GEP-NEN are limited, and ...