• Investigating causal relations between sleep traits and risk of breast cancer in women: Mendelian randomisation study 

      Richmond, Rebecca C.; Anderson, Emma L.; Dashti, Hassan S.; Jones, Samuel E.; Lane, Jacqueline M.; Strand, Linn B; Brumpton, Ben Michael; Rutter, Martin K.; Wood, Andrew R.; Straif, Kurt; Relton, Caroline L.; Munafò, Marcus; Frayling, Timothy M.; Martin, Richard M.; Saxena, Richa; Weedon, Michael N.; Lawlor, Debbie A.; Smith, George Davey (Peer reviewed; Journal article, 2019)
      Objective To examine whether sleep traits have a causal effect on risk of breast cancer. Design Mendelian randomisation study. Setting UK Biobank prospective cohort study and Breast Cancer Association Consortium ...
    • Investigating novel biomarkers of immune activation and modulation in the context of sedentary behaviour: a multicentre prospective ischemic stroke cohort study 

      Alme, Katinka Nordheim; Askim, Torunn; Assmus, Jörg; Mollnes, Tom Eirik; Naik, Mala; Næss, Halvor; Saltvedt, Ingvild; Ueland, Per-Magne; Ulvik, Arve; Knapskog, Anne-Brita (Peer reviewed; Journal article, 2021)
      Background Sedentary behaviour is associated with disease, but the molecular mechanisms are not understood. Valid biomarkers with predictive and explanatory properties are required. Therefore, we have investigated traditional ...
    • Investigating optimal β-cell-preserving treatment in latent autoimmune diabetes in adults: Results from a 21-month randomized trial 

      Hals, Ingrid Kathrin; Fleiner, Hanne Fiskvik; Reimers, Nina; Astor, Marianne; Filipsson, Karin; Ma, Zuheng; Grill, Valdemar Erik Robert; Björklund, Anneli (Peer reviewed; Journal article, 2019)
      Aims To compare outcomes of glucagon‐stimulated C‐peptide tests (GSCTs) in people with latent autoimmune diabetes in adults (LADA) after a 21‐month intervention with either insulin or the dipeptidyl peptidase‐4 inhibitor ...
    • Investigating the causal interplay between sleep traits and risk of acute myocardial infarction: a Mendelian randomization study 

      Arora, Nikhil; Bhatta, Laxmi; Skarpsno, Eivind Schjelderup; Dalen, Håvard; Åsvold, Bjørn Olav; Brumpton, Ben Michael; Richmond, Rebecca C.; Strand, Linn Beate (Peer reviewed; Journal article, 2023)
      Background Few studies have investigated the joint effects of sleep traits on the risk of acute myocardial infarction (AMI). No previous study has used factorial Mendelian randomization (MR) which may reduce confounding, ...
    • Investigating the effect of sex and ketosis on weight-loss-induced changes in appetite 

      Lyngstad, Anna; Nymo, Siren; Coutinho, Silvia; Rehfeld, Jens F.; Truby, Helen; Kulseng, Bård Eirik; Martins, Catia (Peer reviewed; Journal article, 2019)
      Background Diet-induced weight loss (WL) is usually accompanied by increased appetite, a response that seems to be absent when ketogenic diets are used. It remains unknown if sex modulates the appetite suppressant effect ...
    • Irisin reduces orthodontic tooth movement in rats by promoting the osteogenic potential in the periodontal ligament 

      Yang, Yang; Pullisaar, Helen; Stunes, Astrid Kamilla; Parreiras Nogueira, Liebert; Syversen, Unni; Reseland, Janne Elin (Peer reviewed; Journal article, 2023)
      Objectives Positive effects of irisin on osteogenic differentiation of periodontal ligament (PDL) cells have been identified previously, this study aims to examine its effect on orthodontic tooth movement (OTM) in ...
    • Is long-bout sedentary behaviour associated with long-Term glucose levels 3 months after acute ischaemic stroke? A prospective observational cohort study 

      Alme, Katinka Nordheim; Knapskog, Anne Brita; Næss, Halvor; Naik, Mala; Beyer, Mona K.; Ellekjær, Hanne; English, Coralie; Ihle-Hansen, Hege; Kummeneje, Camilla S.; Munthe-Kaas, Ragnhild; Saltvedt, Ingvild; Seljeseth, Yngve Müller; Tan, Xiang chun; Thingstad, Pernille; Askim, Torunn (Peer reviewed; Journal article, 2020)
      Background and purpose Sedentary behaviour is a risk factor for vascular disease and stroke patients are more sedentary than their age-matched peers. The association with glucose levels, as a potential mediator, is unclear, ...
    • Is pituitary MRI screening necessary in cluster headache? 

      Grangeon, Lou; OConnor, Emer; Danno, Daisuke; Ngoc, Thanh Mai Pham; Cheema, Sanjay; Tronvik, Erling Andreas; Davagnanam, Indran; Matharu, Manjit (Peer reviewed; Journal article, 2021)
      Objective To determine the prevalence and clinical predictors of pituitary adenomas in cluster headache patients, in order to determine the necessity of performing dedicated pituitary magnetic resonance imaging in patients ...
    • Is police investigation of rape biased by characteristics of victims? 

      Vik, Bjarte Frode; Rasmussen, Kirsten; Schei, Berit; Hagemann, Cecilie Therese (Peer reviewed; Journal article, 2020)
      Aim To explore differences in police investigations between cases of rape against women with and without vulnerability factors. Methods Retrospective, descriptive study of cases of rape against women ≥16 years of age. ...
    • Is the anatomical distribution of low-grade gliomas linked to regions of gliogenesis? 

      Skjulsvik, Anne Jarstein; Bø, Hans Kristian; Jakola, Asgeir S; Berntsen, Erik Magnus; Bø, Lars Eirik; Reinertsen, Ingerid; Myrmel, Kristin Smistad; Sjåvik, Kristin; Åberg, Kristin; Berg, Thomas; Hong, Yan Dai; Kloster, Roar; Torp, Sverre Helge; Solheim, Ole (Peer reviewed; Journal article, 2020)
      Introduction According to the stem cell theory, two neurogenic niches in the adult human brain may harbor cells that initiate the formation of gliomas: The larger subventricular zone (SVZ) and the subgranular zone (SGZ) ...
    • Is there a causal relationship between stress and migraine? Current evidence and implications for management 

      Stubberud, Anker; Buse, Dawn C.; Kristoffersen, Espen Saxhaug; Linde, Mattias; Tronvik, Erling Andreas (Peer reviewed; Journal article, 2021)
      Background The purpose of this narrative review is to examine the literature investigating a causal relationship between stress and migraine and evaluate its implications for managing migraine. Methods PubMed, PsycINFO and ...
    • Is there a genetic cause of appetite loss? - An explorative study in 1853 cancer patients 

      Solheim, Tora Skeidsvoll; Fayers, Peter; Fladvad, Torill; Tan, Ben; Skorpen, Frank; Fearon, Kenneth C.; Baracos, Vickie; Klepstad, Pål; Strasser, Florian; Kaasa, Stein (Journal article; Peer reviewed, 2012)
      Background Appetite loss has a major impact on cancer patients. It is exceedingly prevalent, is a prognostic indicator and is associated with inferior quality of life. Cachexia is a multi‐factorial syndrome defined by a ...
    • Is there a relationship between the stratum corneum thickness and that of the viable parts of tumour cells in basal cell carcinoma? 

      Foss, Olav A.; Mjønes, Patricia; Fismen, Silje; Christensen, Eidi (Journal article; Peer reviewed, 2016)
      Basal cell carcinoma (BCC) is an invasive epithelial skin tumour. The thickness of the outermost epidermal layer of the skin, the stratum corneum (SC), influences drug uptake and penetration into tumour and may thereby ...
    • Is there a U-shaped relationship between physical activity in leisure time and risk of chronic low back pain? A follow-up in the HUNT Study 

      HEUCH, INGRID; Heuch, Ivar; Hagen, Knut; Zwart, John-Anker (Journal article; Peer reviewed, 2016)
      Background Physical activity in leisure time is often considered to have favourable effects on the risk of low back pain (LBP), but demonstrating a definite association in epidemiological studies has proven difficult. The ...
    • Is there a weekend effect on mortality rate and outcome for moderate and severe traumatic brain injury? A population-based, observational cohort study 

      Andreassen, Joakim Stray; Thorsen, Kenneth; Søreide, Kjetil; Werner, David Andreas Thomas; Weber, Clemens (Peer reviewed; Journal article, 2022)
      Purpose - The aim of the study was to analyse patient and injury characteristics and the effects of weekend admissions on mortality rate and outcome after moderate and severe traumatic brain injuries. Methods - This is ...
    • ISIDOG Consensus Guidelines on COVID-19 Vaccination for Women before, during and after Pregnancy 

      Donders, Gilbert; Grinceviciene, Svitrigaile; Haldre, Kai; Lonnee-Hoffmann, Risa; Donders, Francesca; Tsiakalos, Aristotelis; Adriaanse, Albert; Martinez de Oliveira, Jose; Ault, Kevin A.; Mendling, Werner (Peer reviewed; Journal article, 2021)
      Introduction. Sars-CoV-2 infection poses particular problems in pregnancy, as the infection more frequently causes severe complications than in unaffected pregnant women or nonpregnant women with SARS-CoV-2 infection. Now ...
    • ISIDOG recommendations concerning COVID-19 and pregnancy 

      Donders, Francesca; Lonnee-Hoffmann, Risa; Tsiakalos, Aristotelis; Mendling, Werner; De Oliveira, José Martinez; Judlin, Philippe; Xue, Fengxia; Donders, Gilbert; COVID-19 Guideline Workgroup, ISIDOG (Peer reviewed; Journal article, 2020)
      Providing guidelines to health care workers during a period of rapidly evolving viral pandemic infections is not an easy task, but it is extremely necessary in order to coordinate appropriate action so that all patients ...
    • Kan en totimers artroseskole i ortopedisk spesialisthelsetjeneste bedre sykdomsmestring hos personer med hofte- og kneartrose? En kohortestudie 

      Engdal, Monika; Bjerkan, Bente; Egeberg, Tarjei; Brændvik, Siri Merete (Peer reviewed; Journal article, 2021)
      Hensikt: Å evaluere artroseskole i ortopedisk spesialisthelsetjeneste med hensyn til sykdomsmestring og fysisk funksjon etter fire måneder og leddoverlevelse etter ett år, samt undersøke i hvor stor grad pasienter med ...
    • Kan fysisk aktivitet redusere sykefravær og uføretrygding? 

      Fimland, Marius Steiro; Woodhouse, Astrid; Vasseljen, Ottar; Gismervik, Sigmund Østgård; Jacobsen, Henrik Børsting; Johnsen, Roar (Journal article; Peer reviewed, 2013)
      Innledning: Sykefravær og uføretrygding er betydelige folkehelseproblem med store konsekvenser for enkeltindivid, familie og samfunn. Fysisk aktivitet og trening har mange helsegevinster, og anvendes både i forebygging og ...
    • Kartlegging av den akuttmedisinske kjeden 

      Idland, Siri; Morken, Tone; Allertsen, Merete; Solberg, Line Remme; Halvorsen, Karoline Stadheim; Isern, Cecilie Benedicte; Kongsgård, Håvard Wahl; Nilsen, Jan Erik (Research report, 2019)
      Denne rapporten er utført på bestilling fra Helsedirektoratet, og er et samarbeidsprosjekt mellom NAKOS og NKLM. Bestillingen var en såkalt trendanalyse av den akuttmedisinske kjeden: ambulansetjenesten, AMK-sentralene, ...