Browsing Publikasjoner fra Cristin - St. Olavs hospital by Title
Now showing items 30-49 of 1611
-
Accuracy of breast cancer lesion classification using intravoxel incoherent motion diffusion-weighted imaging is improved by the inclusion of global or local prior knowledge with bayesian methods
(Journal article; Peer reviewed, 2019)Background Diffusion‐weighted MRI (DWI) has potential to noninvasively characterize breast cancer lesions; models such as intravoxel incoherent motion (IVIM) provide pseudodiffusion parameters that reflect tissue perfusion, ... -
Accuracy of neuropathic pain measurements in patients with symptoms of polyneuropathy: validation of painDETECT, Self-Completed Leeds Assessment of Neuropathic Symptoms and Signs, and Douleur Neuropathique 4
(Peer reviewed; Journal article, 2022)Pain is a common symptom in patients referred to polyneuropathy assessment. Diagnostic evaluation and choice of treatment may depend on whether the pain is likely to be neuropathic or not. This study aimed to investigate ... -
ACL Reconstruction Patients Have Increased Risk of Knee Arthroplasty at 15 Years of Follow-up : Data from the Norwegian Knee Ligament Register and the Norwegian Arthroplasty Register from 2004 to 2020
(Peer reviewed; Journal article, 2022)Background: Anterior cruciate ligament (ACL) injury is considered a risk factor for osteoarthritis. The primary aim of the present study was to investigate the cumulative risk of, and risk factors associated with, a ... -
Active conventional treatment and three different biological treatments in early rheumatoid arthritis: Phase IV investigator initiated, randomised, observer blinded clinical trial
(Peer reviewed; Journal article, 2020)Objective To evaluate and compare benefits and harms of three biological treatments with different modes of action versus active conventional treatment in patients with early rheumatoid arthritis. Design Investigator ... -
Activins as Dual Specificity TGF-β Family Molecules: SMAD-Activation via Activin- and BMP-Type 1 Receptors
(Peer reviewed; Journal article, 2020)Activins belong to the transforming growth factor (TGF)-β family of multifunctional cytokines and signal via the activin receptors ALK4 or ALK7 to activate the SMAD2/3 pathway. In some cases, activins also signal via the ... -
Acute Diffusion Tensor and Kurtosis Imaging and Outcome following Mild Traumatic Brain Injury
(Peer reviewed; Journal article, 2021)In this prospective cohort study, we investigated associations between acute diffusion tensor imaging (DTI) and diffusion kurtosis imaging (DKI) metrics and persistent post-concussion symptoms (PPCS) 3 months after mild ... -
Acute kidney injury in patients with COVID-19 in the intensive care unit: Evaluation of risk factors and mortality in a national cohort
(Peer reviewed; Journal article, 2022)Objectives Acute kidney injury (AKI) is a frequent complication among critical ill patients with COVID-19, but the actual incidence is unknown as AKI-incidence varies from 25% to 89% in intensive care unit (ICU) populations. ... -
Admissions and surgery as indicators of hospital functions in Sierra Leone during the west-African Ebola outbreak
(Journal article; Peer reviewed, 2018)Background In an attempt to assess the effects of the Ebola viral disease (EVD) on hospital functions in Sierra Leone, the aim of this study was to evaluate changes in provisions of surgery and non-Ebola admissions during ... -
Adolescent siblings of children with cancer: a qualitative study from a salutogenic health promotion perspective
(Peer reviewed; Journal article, 2020)Purpose: To explore the experiences of adolescents with a sibling suffering from cancer from a salutogenic health promotion perspective. Methods: Seven female siblings aged 13–17 years were interviewed. The interviews ... -
Adverse childhood experiences and their association with substance use disorders in adulthood: A general population study (Young-HUNT)
(Peer reviewed; Journal article, 2023)Aim To investigate the association of adverse childhood experiences (ACEs) and substance use disorders (alcohol and illicit drug use disorders), specifically by gender, in a large longitudinal non-clinical population ... -
Adverse events of exercise therapy in randomised controlled trials: A systematic review and meta-analysis
(Journal article; Peer reviewed, 2019)Objective To evaluate the relative risk (RR) of serious and non-serious adverse events in patients treated with exercise therapy compared with those in a non-exercising control group. Design Systematic review and ... -
Adverse events with fatal outcome associated with alemtuzumab treatment in multiple sclerosis
(Journal article; Peer reviewed, 2019)Objective Sporadic fatal adverse events have been reported during treatment of multiple sclerosis with alemtuzumab. To provide a systematic overview, we searched the centralized European Medicines Agency database of ... -
Adverse pregnancy outcomes among women in Norway with gestational diabetes using three diagnostic criteria
(Peer reviewed; Journal article, 2023)Introduction The aim of this study was to examine the risk of adverse perinatal outcomes in women diagnosed with GDM by the World Health Organization (WHO) 1999 criteria, and in those retrospectively identified by the ... -
Aerobic high-intensity intervals improve V̇O2max more than supramaximal sprint intervals in females, similar to males
(Journal article; Peer reviewed, 2023)Introduction: Maximal oxygen uptake (V̇O2max) is a pivotal factor for aerobic endurance performance. Recently, aerobic high-intensity interval training (HIIT) was documented to be superior to sprint interval training (SIT) ... -
Age at Menarche, age at Natural Menopause, and Risk of Lung and Colorectal Cancers: A Mendelian Randomization Study
(Peer reviewed; Journal article, 2023)Background: The roles of age at menarche and age at menopause in the etiology of lung and colorectal cancers are unclear. Objective: We aimed to investigate potential causal associations between age at menarche, age at ... -
Age- and sex-dependent effects of DNA glycosylase Neil3 on amyloid pathology, adult neurogenesis, and memory in a mouse model of Alzheimer's disease
(Peer reviewed; Journal article, 2022)Oxidative stress generating DNA damage has been shown to be a key characteristic in Alzheimer's disease (AD). However, how it affects the pathogenesis of AD is not yet fully understood. Neil3 is a DNA glycosylase initiating ... -
Age-adjusted CSF t-tau and NfL do not improve diagnostic accuracy for prodromal Alzheimer’s Disease
(Journal article; Peer reviewed, 2024)Cerebrospinal fluid total-tau (t-tau) and neurofilament light chain (NfL) are biomarkers of neurodegeneration and are increased in Alzheimer’s disease (AD). In order to adjust for age-related increases in t-tau and NfL, ... -
Age-of-onset information helps identify 76 genetic variants associated with allergic disease
(Peer reviewed; Journal article, 2020)Risk factors that contribute to inter-individual differences in the age-of-onset of allergic diseases are poorly understood. The aim of this study was to identify genetic risk variants associated with the age at which ... -
AI-driven attenuation correction for brain PET/MRI: Clinical evaluation of a dementia cohort and importance of the training group size
(Peer reviewed; Journal article, 2020)Introduction Robust and reliable attenuation correction (AC) is a prerequisite for accurate quantification of activity concentration. In combined PET/MRI, AC is challenged by the lack of bone signal in the MRI from which ...