Browsing Publikasjoner fra Cristin - St. Olavs hospital by Title
Now showing items 1124-1143 of 1611
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Persistence of disseminated tumor cells after neoadjuvant treatment for locally advanced breast cancer predicts poor survival
(Journal article; Peer reviewed, 2012)Introduction Presence of disseminated tumor cells (DTCs) in bone marrow (BM) and circulating tumor cells (CTC) in peripheral blood (PB) predicts reduced survival in early breast cancer. The aim of this study was to determine ... -
Persistent pulmonary pathology after COVID-19 is associated with high viral load, weak antibody response, and high levels of matrix metalloproteinase-9
(Peer reviewed; Journal article, 2021)The association between pulmonary sequelae and markers of disease severity, as well as pro-fibrotic mediators, were studied in 108 patients 3 months after hospital admission for COVID-19. The COPD assessment test (CAT-score), ... -
Persistent Short Sleep from Childhood to Adolescence: Child, Parent and Peer Predictors
(Peer reviewed; Journal article, 2021)Purpose: Many children have periods when they sleep too little, with widely recognized detrimental effects. Less is known about persistent short sleep during childhood. Therefore, the present study aimed to investigate the ... -
Personal Activity Intelligence and Ischemic Heart Disease in a Healthy Population: China Kadoorie Biobank Study
(Peer reviewed; Journal article, 2022)Background: Personal Activity Intelligence (PAI) is a physical activity metric that translates heart rate during physical activity into a simple score, where a weekly score of 100 or greater is associated with a lower risk ... -
Persons with rheumatoid arthritis have higher barriers to physical activity than controls: a cross-sectional study using the Facilitators and Barriers to Physical Activity Questionnaire (FasBarPAQ)
(Peer reviewed; Journal article, 2023)Facilitators and barriers to performing physical activity (PA) may vary among persons with rheumatoid arthritis (RA) as well as between RA patients and healthy individuals. Primary objective: To investigate associations ... -
Phagocytosis of live and dead Escherichia coli and Staphylococcus aureus in human whole blood is markedly reduced by combined inhibition of C5aR1 and CD14
(Journal article; Peer reviewed, 2019)Background Sepsis is a dysregulated host response to infection. The aim of this study was to investigate the effects of complement- and CD14 inhibition on phagocytosis of live and dead Gram-negative and Gram-positive ... -
Pharmacokinetic data on brivaracetam, lacosamide and Perampanel during pregnancy and lactation
(Peer reviewed; Journal article, 2021)We present pharmacokinetic data during pregnancy and lactation for brivaracetam, lacosamide and perampanel based on two case studies. Patient 1 used brivaracetam as monotherapy and gave birth to twins. Patient 2 used a ... -
Pharmacokinetics of a novel, approved, 1.4-mg intranasal naloxone formulation for reversal of opioid overdose—a randomized controlled trial
(Peer reviewed; Journal article, 2019)Background and aims Intranasal (i.n.) naloxone is an established treatment for opioid overdose. Anyone likely to witness an overdose should have access to the antidote. We aimed to determine whether an i.n. formulation ... -
Pharmacokinetics of Intraperitoneally Delivered Glucagon in Pigs: A Hypothesis of First Pass Metabolism
(Peer reviewed; Journal article, 2021)Background and Objective Artificial pancreases administering low-dose glucagon in addition to insulin have the scope to improve glucose control in patients with diabetes mellitus type 1. If such a device were to deliver ... -
Pharmacokinetics of propofol in severely obese surgical patients
(Peer reviewed; Journal article, 2024) -
Phenotypic and genotypic characterisation of thymine auxotrophy in Escherichia coli isolated from a patient with recurrent bloodstream infection
(Peer reviewed; Journal article, 2022)Introduction Thymine auxotrophic in vitro mutants of Escherichia coli were first reported in the mid-20th century. Later, thymine-dependent clinical strains of E. coli as well as other Enterobacterales, Enterococcus ... -
Phosphatases of regenerating liver are key regulators of metabolism in cancer cells - role of Serine/Glycine metabolism
(Peer reviewed; Journal article, 2022)Purpose of review Phosphatases of regenerating liver (PRL) are dual-specificity phosphatases and comprise three members, PRL-1, -2 and -3. Despite the importance of PRLs as oncoproteins, there is no consensus function ... -
Phylogeographical pattern of Francisella tularensis in a nationwide outbreak of tularaemia in Norway, 2011
(Journal article; Peer reviewed, 2015)In 2011, a nationwide outbreak of tularaemia occurred in Norway with 180 recorded cases. It was associated with the largest peak in lemming density seen in 40 years. Francisella tularensis was isolated from 18 patients. ... -
Physical activity after inpatient occupational rehabilitation: secondary outcomes of two randomized controlled trials
(Peer reviewed; Journal article, 2019)Objectives: To assess whether inpatient multicomponent occupational rehabilitation, including physical activity (PA), increases the PA level of participants more than an outpatient program without PA, and whether changes ... -
Physical activity behavior and its association with global cognitive function three months after stroke: The Nor-COAST study.
(Peer reviewed; Journal article, 2023)Objective - The purposes of this study were to determine the association between physical activity (PA) behavior and global cognitive function 3 months after stroke and to explore the role of physical capacity as a mediating ... -
Physical Activity, Genetic Susceptibility, and the Risk of Latent Autoimmune Diabetes in Adults and Type 2 Diabetes
(Peer reviewed; Journal article, 2020)Purpose Physical activity (PA) has been linked to a reduced risk of type 2 diabetes by reducing weight and improving insulin sensitivity. We investigated whether PA is associated with a lower incidence of latent autoimmune ... -
Physical diagnoses in nursing home residents - is dementia or severity of dementia of importance?
(Journal article; Peer reviewed, 2018)Background Dementia and physical morbidity are primary reasons for nursing home admission globally. However, data on physical morbidity in nursing home residents with and without dementia are scarce. The first aim of the ... -
Physical function endpoints in cancer cachexia clinical trials: Systematic Review 1 of the cachexia endpoints series
(Peer reviewed; Journal article, 2023)In cancer cachexia trials, measures of physical function are commonly used as endpoints. For drug trials to obtain regulatory approval, efficacy in physical function endpoints may be needed alongside other measures. However, ... -
Physical Performance and Cognition as Predictors of Instrumental Activities of Daily Living After Stroke: A Prospective Multicenter Cohort Study
(Journal article; Peer reviewed, 2022)Objective: To investigate whether cognition and physical performance, both separately and combined, 3 months post stroke predict change in instrumental activities of daily living (IADL) up to 18 months and whether different ... -
Physical rehabilitation in patients with head and neck cancer: Impact on health-related quality of life and suitability of a post-treatment program
(Peer reviewed; Journal article, 2020)Objective: Physical rehabilitation programs hold the potential to mitigate deterioration in health-related quality of life (HRQoL) in patients with head and neck cancer. The objective was to assess development in relevant ...