Browsing Publikasjoner fra Cristin - St. Olavs hospital by Title
Now showing items 1104-1123 of 1548
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Placental inflammation by HMGB1 activation of TLR4 at the syncytium
(Peer reviewed; Journal article, 2018)Introduction: Normal pregnancy is characterized by an elevated inflammatory state involving the placenta. The placental inflammation is further increased in preeclampsia, resulting in release of harmful danger signals to ... -
Placental inflammation by HMGB1 activation of TLR4 at the syncytium
(Peer reviewed; Journal article, 2018)Normal pregnancy is characterized by an elevated inflammatory state involving the placenta. The placental inflammation is further increased in preeclampsia, resulting in release of harmful danger signals to the maternal ... -
Plasma apolipoprotein E levels in longitudinally followed patients with mild cognitive impairment and Alzheimer’s disease
(Peer reviewed; Journal article, 2022)Background Low levels of plasma apolipoprotein E (apoE) and presence of the APOE ε4 allele are associated with an increased risk of Alzheimer’s disease (AD). Although the increased risk of AD in APOE ε4-carriers is ... -
Plasma brain-derived tau is an amyloid-associated neurodegeneration biomarker in Alzheimer’s disease
(Journal article; Peer reviewed, 2024)Staging amyloid-beta (Aβ) pathophysiology according to the intensity of neurodegeneration could identify individuals at risk for cognitive decline in Alzheimer’s disease (AD). In blood, phosphorylated tau (p-tau) associates ... -
Plasma Levels of the Cytokines B Cell-Activating Factor (BAFF) and A Proliferation-Inducing Ligand (APRIL) in Schizophrenia, Bipolar, and Major Depressive Disorder: A Cross Sectional, Multisite Study
(Peer reviewed; Journal article, 2021)Background Immune dysfunction has been implicated in the pathogenesis of schizophrenia and other nonaffective psychosis (SCZ), bipolar spectrum disorder (BIP) and major depressive disorder (MDD). The cytokines B cell-activating ... -
Plasma methylmalonic acid predicts risk of acute myocardial infarction and mortality in patients with coronary heart disease: A prospective 2-cohort study
(Peer reviewed; Journal article, 2023)Background Elevated plasma methylmalonic acid (MMA) is reported in patients with established coronary heart disease (CHD) and is considered a marker of vitamin B12 deficiency. Moreover, MMA-dependent reactions have been ... -
Plasma n-6 Polyunsaturated Fatty Acid Levels and Survival in Renal Transplantation
(Journal article; Peer reviewed, 2018)Objective The major n-6 polyunsaturated fatty acids linoleic acid (LA) and arachidonic acid (AA) play a role in inflammation and glucose metabolism, which could affect patient and renal transplant survival. Design and ... -
Plasticity of hippocampal memories in humans
(Journal article; Peer reviewed, 2017)The human hippocampus is a brain region that supports episodic and spatial memory. Recent experiments have drawn on animal research and computational modelling to reveal how the unique computations and representations of ... -
Pleural Empyema Caused by Streptococcus intermedius and Fusobacterium nucleatum: A Distinct Entity of Pleural Infections
(Peer reviewed; Journal article, 2023)Background - Many community-acquired pleural infections are caused by facultative and anaerobic bacteria from the human oral microbiota. The epidemiology, clinical characteristics, pathogenesis, and etiology of such ... -
Pneumonitis and fibrosis after breast cancer radiotherapy: occurrence and treatment-related predictors
(Peer reviewed; Journal article, 2021)Background Radiation pneumonitis (RP) and radiation fibrosis (RF) are common side effects after breast cancer (BC) radiotherapy (RT). However, there is a great variation in the frequency of RP and RF. This study presents ... -
Polycystic ovary syndrome and pregnancy - From a clinical perspective
(Peer reviewed; Journal article, 2020)For decades, infertility and metabolic health challenges have been the main concerns for women diagnosed with polycystic ovary syndrome (PCOS). Poorer pregnancy outcomes and obstetric complications have only recently been ... -
Pooled analysis of WHO Surgical Safety Checklist use and mortality after emergency laparotomy
(Peer reviewed; Journal article, 2019)Background The World Health Organization (WHO) Surgical Safety Checklist has fostered safe practice for 10 years, yet its place in emergency surgery has not been assessed on a global scale. The aim of this study was to ... -
Poor prognosis patients with inoperable locally advanced NSCLC and large tumors benefit from palliative chemoradiotherapy: A subset analysis from a randomized clinical phase III trial
(Peer reviewed; Journal article, 2014)Introduction: Poor prognosis patients with bulky stage III locally advanced non–small-cell lung cancer may not be offered concurrent chemoradiotherapy (CRT). Following a phase III trial concerning the effect of palliative ... -
A population-based study of caesarean section in women with juvenile idiopathic arthritis
(Peer reviewed; Journal article, 2023)Objectives: The literature on delivery methods in women with JIA is limited. Active inflammation is a risk factor for caesarean section (CS) in other arthritic diseases. A CS entails a higher risk for complications than ... -
Post-discharge suicide among high-risk psychiatric inpatients: Risk factors and warnings signs
(Peer reviewed; Journal article, 2023)Background The present study explored the predictive value of a novel suicide risk assessment with regard to suicide deaths within three years of discharge from an acute inpatient unit. The contributions of the different ... -
Post-Fracture Risk Assessment: Target The Centrally Sited Fractures First! A Sub-Study of NoFRACT
(Peer reviewed; Journal article, 2019)The location of osteoporotic fragility fractures adds crucial information to post-fracture risk estimation. Triaging patients according tofracture site for secondary fracture prevention can therefore be of interest to ... -
Post-traumatic epidural tension pneumocephalus: a case report
(Journal article; Peer reviewed, 2015)Abstract Introduction: Pneumocephalus is usually a self-limiting condition commonly associated with neurosurgical interventions, head and facial trauma. In contrast, tension pneumocephalus is extremely rare, and considered ... -
Post-treatment work patterns amongst survivors of lymphoma treated with high-dose chemotherapy with autologous stem-cell transplantation
(Peer reviewed; Journal article, 2021)Background This study describes post-treatment work patterns in lymphoma survivors treated with high-dose chemotherapy with autologous stem-cell transplantation (HDT-ASCT). It aims to identify determinants for labour force ... -
Postmortem Assessment of Isolated Congenital Heart Defects Remains Essential Following Termination of Pregnancy
(Peer reviewed; Journal article, 2021)Objectives: To investigate the correlation between prenatal ultrasound (US) and autopsy findings in pregnancies terminated due to isolated congenital heart defects (CHDs), including CHDs associated with heterotaxy syndrome. ... -
Postmortem toxicological analyses of blood samples from 107 patients receiving opioid agonist treatment: substances detected and pooled opioid and benzodiazepine concentrations
(Peer reviewed; Journal article, 2020)Aims: To present the substances and their concentrations detected postmortem in patients receiving opioid agonist treatment (OAT) stratified by cause of death, estimate the pooled opioid and benzodiazepine concentrations ...