• Genome-wide association identifies the first risk loci for psychosis in Alzheimer disease 

      DeMichele-Sweet, Mary Ann A.; Klei, Lambertus; Creese, Byron; Harwood, Janet C.; Weamer, Elise A.; McClain, Lora; Sims, Rebekka; Hernández, Isabel; Moreno-Grau, Sonia; Tárraga, Lluís; Boada, Mercè; Alarcón-Martín, Emilio; Valero, Sergi; Liu, Yushi; Hooli, Basavaraj; Aarsland, Dag; Selbæk, Geir; Bergh, Sverre; Rongve, Arvid; Saltvedt, Ingvild; Skjellegrind, Håvard; Engdahl, Bo Lars; Stordal, Eystein; Andreassen, Ole Andreas; Djurovic, Srdjan; Athanasiu, Lavinia; Seripa, Davide; Borroni, Barbara; Albani, Diego; Forloni, Gianluigi; Mecocci, Patrizia; Seretti, Alessandro; De Ronchi, Diana; Politis, Antonis; Williams, Julie; Mayeux, Richard; Foroud, Tatiana; Ruiz, Agustin; Ballard, Clive; Holmans, Peter; Lopez, Oscar L.; Kamboh, M. Ilyas; Devlin, Bernie; Sweet, Robert A. (Peer reviewed; Journal article, 2021)
      Psychotic symptoms, defined as the occurrence of delusions or hallucinations, are frequent in Alzheimer disease (AD with psychosis, AD + P). AD + P affects ~50% of individuals with AD, identifies a subgroup with poor ...
    • Genome-Wide Association Study Identifies New Genetic Determinants of Cardiorespiratory Fitness: The Trøndelag Health Study 

      Klevjer, Marie; Nordeidet, Ada Nilsen; Hansen, Ailin Falkmo; Madssen, Erik; Wisløff, Ulrik; Brumpton, Ben Michael; Bye, Anja (Peer reviewed; Journal article, 2022)
      Purpose Low cardiorespiratory fitness (CRF) is a major risk factor for cardiovascular disease (CVD) and a stronger predictor of CVD morbidity and mortality than established risk factors. The genetic component of CRF, ...
    • Genome-wide association study of intracranial aneurysms identifies 17 risk loci and genetic overlap with clinical risk factors 

      Bakker, Mark K.; Spek, Rick A.A. var der; Rheenen, Wouter van; Morel, Sandrine; Bourcier, Romain; Hostettler, Isabel C.; Varinder, S. Alg; Eijk, Kristel R. van; Koido, Masaru; Akiyama, Masato; Terao, Chikashi; Matsuda, Koichi; Walters, Robin G.; Lin, Kuang; Li, Liming; Millwood, Iona Y.; Chen, Zhengming; Rouleau, Guy A.; Zhou, Sirui; Rannikmae, Kristiina; Sudlow, Cathie L.M.; Houlden, Henry; Berg, Leonard H. van den; Dina, Christian; Naggara, Olivier; Gentric, Jean-Christophe; Shotar, Eimad; Eugène, François; Desal, Hubert; Winsvold, Bendik K S; Børte, Sigrid; Johnsen, Marianne Bakke; Brumpton, Ben Michael; Sandvei, Marie Søfteland; Willer, Cristen J.; Hveem, Kristian; Zwart, John-Anker; Verschuren, W.M. Monique; Friedrich, Christoph M.; Hirsch, Sven; Schilling, Sabine; Dauvillier, Jérôme; Martin, Olivier; Jones, Gregory T.; Bown, Matthew J.; Ko, Nerissa U.; Kim, Helen; Coleman, Jonathan R. I.; Breen, Gerome; Zaroff, Jonathan G. (Peer reviewed; Journal article, 2020)
      Rupture of an intracranial aneurysm leads to subarachnoid hemorrhage, a severe type of stroke. To discover new risk loci and the genetic architecture of intracranial aneurysms, we performed a cross-ancestry, genome-wide ...
    • Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth 

      Beaumont, Robin N.; Flatley, Christopher; Vaudel, Marc; Wu, Xiaoping; Chen, Jing; Moen, Gunn-Helen Øiseth; Skotte, Line; Helgeland, Øyvind; Solé-Navais, Pol; Banasik, Karina; Albiñana, Clara; Ronkainen, Justiina; Fadista, João; Stinson, Sara Elizabeth; Trajanoska, Katerina; Wang, Carol A.; Westergaard, David; Srinivasan, Sundararajan; Sánchez-Soriano, Carlos; Bilbao, Jose Ramon; Allard, Catherine; Groleau, Marika; Kuulasmaa, Teemu; Leirer, Daniel J.; White, Frédérique; Jacques, Pierre-Étienne; Cheng, Haoxiang; Hao, Ke; Andreassen, Ole; Åsvold, Bjørn Olav; Atalay, Mustafa; Bhatta, Laxmi; Bouchard, Luigi; Brumpton, Ben Michael; Brunak, Søren; Bybjerg-Grauholm, Jonas; Ebbing, Cathrine; Elliott, Paul; Engelbrechtsen, Line; Erikstrup, Christian; Estarlich, Marisa; Franks, Stephen; Gaillard, Romy; Geller, Frank; Grove, Jakob; Hougaard, David M.; Kajantie, Eero Olavi; Morgen, Camilla S.; Nøhr, Ellen Aagaard; Nyegaard, Mette; Palmer, Colin N. A.; Pedersen, Ole Birger; Rivadeneira, Fernando; Sebert, Sylvain; Shields, Beverley M.; Stoltenberg, Camilla; Surakka, Ida; Thørner, Lise Wegner; Ullum, Henrik; Vaarasmaki, Marja; Vilhjalmsson, Bjarni J.; Willer, Cristen J.; Lakka, Timo A.; Gybel-Brask, Dorte; Bustamante, Mariona; Hansen, Torben; Pearson, Ewan R.; Reynolds, Rebecca M.; Ostrowski, Sisse R.; Pennell, Craig E.; Jaddoe, Vincent W. V.; Felix, Janine F.; Hattersley, Andrew T.; Melbye, Mads; Lawlor, Deborah A.; Hveem, Kristian; Werge, Thomas; Nielsen, Henriette Svarre; Magnus, Per Minor; Evans, David M.; Jacobsson, Bo; Järvelin, Marjo-Riitta; Zhang, Ge; Hivert, Marie-France; Johansson, Stefan; Freathy, Rachel M.; Feenstra, Bjarke; Njølstad, Pål Rasmus (Peer reviewed; Journal article, 2023)
      A well-functioning placenta is essential for fetal and maternal health throughout pregnancy. Using placental weight as a proxy for placental growth, we report genome-wide association analyses in the fetal (n = 65,405), ...
    • Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk 

      Jansen, Iris E.; Savage, Jeanne E.; Watanabe, Kyoko; Bryois, Julien; Williams, Dylan M.; Steinberg, Stacy; Sealock, Julia; Karlsson, Ida K.; Hägg, Sara; Athanasiu, Lavinia; Voyle, Nicola; Proitsi, Petroula; Witoelar, Aree; Stringer, Sven; Aarsland, Dag; Almdahl, Ina Selseth; Andersen, Fred; Bergh, Sverre; Bettella, Francesco; Björnsson, Sigurbjörn; Brækhus, Anne; Bråthen, Geir; de Leeuw, Christiaan A.; Desikan, Rahul S.; Djurovic, Srdjan; Dumitrescu, Logan; Fladby, Tormod; Hohman, Timothy J.; Jónsson, Pálmi V.; Kiddle, Steven J; Rongve, Arvid; Saltvedt, Ingvild; Sando, Sigrid Botne; Selbæk, Geir; Shoai, Maryam; Skene, Nathan G.; Snædal, Jón G.; Stordal, Eystein; Ulstein, Ingun; Wang, Yunpeng; White, Linda Rosemary; Hardy, John; Hjerling-Leffler, Jens; Sullivan, Patrick; van der Flier, Wiesje M.; Dobson, Richard; Davis, Lea K; Stefánsson, Hreinn; Stefánsson, Kári; Pedersen, Nancy L; Ripke, Stephan; Andreassen, Ole Andreas; Posthuma, Danielle (Journal article; Peer reviewed, 2019)
      Alzheimer’s disease (AD) is highly heritable and recent studies have identified over 20 disease-associated genomic loci. Yet these only explain a small proportion of the genetic variance, indicating that undiscovered loci ...
    • Genome-wide meta-analysis of iron status biomarkers and the effect of iron on all-cause mortality in HUNT 

      Moksnes, Marta Riise; Graham, Sarah E.; Wu, Kuan-Han; Hansen, Ailin Falkmo; Gagliano Taliun, Sarah A.; Zhou, Wei; Thorstensen, Ketil; Fritsche, Lars; Gill, Dipender; Mason, Amy; Cucca, Francesco; Schlessinger, David; Abecasis, Gonçalo R.; Burgess, Stephen; Åsvold, Bjørn Olav; Nielsen, Jonas Bille; Hveem, Kristian; Willer, Cristen J.; Brumpton, Ben Michael (Peer reviewed; Journal article, 2022)
      Iron is essential for many biological processes, but iron levels must be tightly regulated to avoid harmful effects of both iron deficiency and overload. Here, we perform genome-wide association studies on four iron-related ...
    • Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders. 

      Lee, Phil H.; Antilla, Verneri; Won, Hyejung; Bettella, Francesco; Agartz, Ingrid; Dale, Anders; Nærland, Terje; Elvsåshagen, Torbjørn; Ødegaard, Ketil Joachim; Melle, Ingrid; Knudsen, Gun Peggy Strømstad; Le Hellard, Stephanie; Reichborn-Kjennerud, Ted; Smeland, Olav Bjerkehagen; Andreassen, Ole Andreas; Neale, Benjamin M; Kendler, Kenneth S.; Smoller, Jordan W. (Peer reviewed; Journal article, 2019)
      Genetic influences on psychiatric disorders transcend diagnostic boundaries, suggesting substantial pleiotropy of contributing loci. However, the nature and mechanisms of these pleiotropic effects remain unclear. We performed ...
    • Geographic and socioeconomic inequities in cesarean delivery rates at the district level in Madhya Pradesh, India: A secondary analysis of the national family health survey-5 

      Dutta, Rohini; Tuli, Shagun; Shukla, Minal; Patil, Priti; van Duinen, Aalke Johan; Thivalapill, Neil; Ghoshal, Rakhi; Jayaram, Anusha; Roy, Nobhojit; Gadgil, Anita (Peer reviewed; Journal article, 2023)
      Background In India, caesarean delivery (CD) accounts for 17% of the births, of which 41% occur in private facilities. However, areas to CD in rural areas are limited, particularly for the poor populations. Little information ...
    • Germline pathogenic variants in patients with high-grade gastroenteropancreatic neuroendocrine neoplasms 

      Venizelos, Andreas; Sorbye, Halfdan; Elvebakken, Hege; Perren, Aurel; Lothe, Inger Marie Bowitz; Couvelard, Anne; Hjortland, Geir Olav; Sundlöv, Anna; Svensson, Johanna; Garresori, Herish; Kersten, Christian; Hofsli, Eva; Detlefsen, Sönke; Vestermark, Lene W.; Ladekarl, Morten; Tabaksblat, Elizaveta Mitkina; Knappskog, Stian (Peer reviewed; Journal article, 2023)
      High-grade gastroenteropancreatic (HG-GEP) neuroendocrine neoplasms (NENs) are highly aggressive cancers. The molecular etiology of these tumors remains unclear, and the prevalence of pathogenic germline variants in patients ...
    • Gestational Age, Parent Education, and Education in Adulthood 

      Bilsteen, Josephine; Alenius, Suvi; Bråthen, Magne; Børch, Klaus; Ekstrøm, Claus Thorn; Kajantie, Eero Olavi; Lashkarian, Mariam; Nurhonen, Markku; Risnes, Kari Ravndal; Sandin, Sven; Wel, Kjetil A. van der; Wolke, Dieter; Nybo Andersen, Anne-Marie (Journal article; Peer reviewed, 2021)
      BACKGROUND: Adults born preterm (<37 weeks) have lower educational attainment than those born term. Whether this relationship is modified by family factors such as socioeconomic background is, however, less well known. We ...
    • Gestational weight gain outside the Institute of Medicine recommendations and adverse pregnancy outcomes: analysis using individual participant data from randomised trials 

      Rogozińska, Ewelina; Zamora, Javier; Marlin, Nadine; Betran, Ana Pilar; Astrup, Arne; Bogaerts, Annick; Cecatti, José Guilherme; Dodd, Jodie M.; Facchinetti, Fabio; Geiker, Nina Rica Wium; Haakstad, Lene Annette Hagen; Hauner, Hans; Jensen, Dorte M.; Kinnunen, Tarja I.; Mol, Ben Willem J.; Owens, Julie; Phelan, Suzanne; Renault, Kristina; Salvesen, Kjell Å; Shub, Alexis; Surita, Fernanda; Stafne, Signe Nilssen; Teede, Helena; van Poppel, Mireille N.M.; Vinter, Christina Anne; Khan, Khalid S.; Thangaratinam, Shakila (Journal article; Peer reviewed, 2019)
      Background:High Body Mass Index (BMI) and gestational weight gain (GWG) affect an increasing number ofpregnancies. The Institute of Medicine (IOM) has issued recommendations on the optimal GWG for womenaccording to their ...
    • Gir ACE-hemmere og angiotensinreseptorantagonister økt risiko for alvorlig covid-19? 

      Aamodt, Anne Hege; Bjørk, Marte-Helene; Tronvik, Erling Andreas; Buanes, Eirik Alnes; Stovner, Lars Jacob; Atar, Dan (Peer reviewed; Journal article, 2020)
      Hypertensjon og diabetes mellitus er risikofaktorer for alvorlig covid-19. Det er blitt reist spørsmål om hvorvidt denne assosiasjonen er relatert til bruk av ACE-hemmere og angiotensin II-reseptorblokkere.
    • Gjenvinning av mobilitet etter hoftebrudd – en prospektiv kohortestudie 

      Johansen, Mette; Thingstad, Pernille; Bogen, Bård Erik; Taraldsen, Kristin (Peer reviewed; Journal article, 2020)
      Hensikt: Å undersøke hva som karakteriserer eldre med hoftebrudd som ikke gjenvinner mobilitet, samt å beskrive mengden fysioterapi denne gruppen mottar det første året etter hoftebrudd. Design: Prospektiv kohortestudie. ...
    • Glioblastom hos voksne 

      Schipmann, Stephanie; Sivakanesan, Sarankan; Rath, Daniel Stavne; Brandal, Petter; Vik-Mo, Einar Osland; Bjørås, Magnar; Solheim, Ole Skeidsvoll; Ingebrigtsen, Tor; Sund, Fredrik; Bjerkvig, Rolf; Miletic, Hrvoje; Johannessen, Tor-Christian Aase; Sundstrøm, Terje (Peer reviewed; Journal article, 2023)
      lioblastom er den vanligste formen for primær hjernekreft hos voksne, og sykdommen har en alvorlig prognose. Selv om det er gjort store fremskritt i molekylær karakteristikk, har det ikke vært større gjennombrudd i ...
    • Global longitudinal strain is a more reproducible measure of left ventricular function than ejection fraction regardless of echocardiographic training 

      Karlsen, Sigve; Dahlslett, Thomas; Grenne, Bjørnar; Sjøli, Benthe; Smiseth, Otto A.; Edvardsen, Thor; Brunvand, Harald (Peer reviewed; Journal article, 2019)
      Background: Left ventricular ejection fraction (LVEF) is an established method for evaluation of left ventricular (LV)systolic function. Global longitudinal strain (GLS) by speckle tracking echocardiography seems to be an ...
    • The global prevalence of headache: an update, with analysis of the influences of methodological factors on prevalence estimates 

      Stovner, Lars Jacob; Hagen, Knut; Linde, Mattias; Steiner, Timothy J. (Peer reviewed; Journal article, 2022)
      Background According to the Global Burden of Disease (GBD) study, headache disorders are among the most prevalent and disabling conditions worldwide. GBD builds on epidemiological studies (published and unpublished) ...
    • Global variation in anastomosis and end colostomy formation following left-sided colorectal resection 

      Glasbey, James C.; Adisa, Adewale O.; Costas-Chavarri, Ainhoa; Qureshi, Ahmad U.; Allen-Ingabire, Jean C.; Salem, Hosni Khairy; Lossius, William J; Havemann, Ingemar; Thorsen, Kenneth; Narvestad, Jon; Søreide, Kjetil; Wold, Trude Beate; Nymo, Linn Såve; Veen, Torhild; Kanani, Arezo; Styles, Kristian; Herikstad, Ragnar; Larsen, Johannes Wiik; Søreide, Jon Arne; Jensen, Elisabeth; Gran, Mads; Aahlin, Eirik Kjus; Gaarder, Christine; Monrad-Hansen, Peter Wiel; Næss, Pål Aksel; Lauzikas, Giedrius; Wiborg, Joachim; Holte, Silje Stensholt; Augestad, Knut Magne; Singh, Banipal Gurpreet; Monteleone, Michela Maria Angela; Moe, Thomas Tetens; Schultz, Johannes Kurt; Bliksøen, Marte; Kojo, Anyomih Theophilus Teddy; Tabiri, Stephen; Nepogodiev, Dmitri; Lilford, Richard J.; Harrison, Ewen M.; Pinkney, Thomas; Smart, Neil; Bhangu, Aneel; Ademuyiwa, Adesoji; Aguilera, Maria Lorena; Altamini, Afnan; Alexander, Philip; Al-Saqqa, Sara W.; Borda-Luque, Giuliano; Cornick, Jen; Drake, Thomas M. (Peer reviewed; Journal article, 2019)
      Background: End colostomy rates following colorectal resection vary across institutions in high-income settings, being influenced by patient, disease, surgeon and system factors. This study aimed to assess global variation ...
    • Glucoregulatory Properties of a Protein Hydrolysate from Atlantic Salmon (Salmo salar): Preliminary Characterization and Evaluation of DPP-IV Inhibition and Direct Glucose Uptake In Vitro 

      Bjerknes, Christian; Wubshet, Sileshi Gizachew; Rønning, Sissel Beate; Afseth, Nils Kristian; Crawford, Currie; Framroze, Bomi; Hermansen, Erland (Journal article; Peer reviewed, 2024)
      Metabolic disorders are increasingly prevalent conditions that manifest pathophysiologically along a continuum. Among reported metabolic risk factors, elevated fasting serum glucose (FSG) levels have shown the most substantial ...
    • Growth during infancy and early childhood in children with cerebral palsy: a population-based study 

      Strand, Kristin Melheim; Dahlseng, Magnus Odin; Lydersen, Stian; Rø, Torstein Baade; Finbråten, Ane-Kristine; Jahnsen, Reidun; Andersen, Guro Lillemoen; Vik, Torstein (Peer reviewed; Journal article, 2016)
      Aim To describe growth in infancy and early childhood in children with cerebral palsy (CP). Method One hundred and four children with CP born at minimum 36 weeks' gestation in 2002 to 2010 were included. Prospectively ...
    • Guideline-Recommended Time Less Than 90 Minutes From ECG to Primary Percutaneous Coronary Intervention for ST-Segment–Elevation Myocardial Infarction Is Associated with Major Survival Benefits, Especially in Octogenarians: A Contemporary Report in 11 226 Patients from NORIC 

      Larsen, Alf Inge; Løland, Kjetil Halvorsen; Hovland, Siren; Bleie, Øyvind; Eek, Christian; Fossum, Eigil; Trovik, Thor; Juliebø, Vibeke; Hegbom, Knut; Moer, Rasmus; Larsen, Tomas; Uchto, Michael; Rotevatn, Svein (Peer reviewed; Journal article, 2022)
      Background - Using contemporary data from NORIC (Norwegian Registry of Invasive Cardiology) we investigated the predictive value of patient age and time from ECG diagnosis to sheath insertion (ECG‐2‐sheath) in primary ...