Blar i Publikasjoner fra Cristin - St. Olavs hospital på tittel

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    • Increased circulating IL-18 levels in severe mental disorders indicate systemic inflammasome activation 

      Szabo, Attila; O’Connell, Kevin; Ueland, Thor; Ahmed, Mashhood Sheikh; Agartz, Ingrid; Andreou, Dimitrios; Aukrust, Pål; Boye, Birgitte; Bøen, Erlend; Drange, Ole Kristian; Elvsåshagen, Torbjørn; Engh, John Abel; Hope, Sigrun; Høegh, Margrethe Collier; Joa, Inge; Johnsen, Erik; Kroken, Rune Andreas; Lagerberg, Trine Vik; Lekva, Tove; Malt, Ulrik Fredrik; Melle, Ingrid; Morken, Gunnar; Nærland, Terje; Steen, Vidar Martin; Sørensen, Kjetil; Wedervang-Resell, Kirsten; Auten Weibell, Melissa; Westlye, Lars Tjelta; Steen, Nils Eiel; Andreassen, Ole; Djurovic, Srdjan (Peer reviewed; Journal article, 2022)
      Background Schizophrenia (SCZ) and bipolar disorder (BD) are severe mental illnesses (SMI) that are part of a psychosis continuum, and dysregulated innate immune responses have been suggested to be involved in their ...

    • Increased circulating IL-18 levels in severe mental disorders indicate systemic inflammasome activation 

      Szabo, Attila; O'Connell, Kevin Sean; Ueland, Thor; Sheikh, Mashhood Ahmed; Agartz, Ingrid; Andreou, Dimitrios; Aukrust, Pål; Boye, Birgitte; Bøen, Erlend; Drange, Ole Kristian; Elvsåshagen, Torbjørn; Engh, John; Hope, Sigrun; Høegh, Margrethe Collier; Joa, Inge; Johnsen, Erik; Kroken, Rune Andreas; Lagerberg, Trine Vik; Lekva, Tove; Malt, Ulrik Fredrik; Melle, Ingrid; Morken, Gunnar; Nærland, Terje; Steen, Vidar Martin; Sørensen, Kjetil; Wedervang-Resell, Kirsten; Weibell, Melissa Anne Elin Authen; Westlye, Lars Tjelta; Steen, Nils Eiel; Andreassen, Ole; Djurovic, Srdjan (Peer reviewed; Journal article, 2021)
      Background -Schizophrenia (SCZ) and bipolar disorder (BD) are severe mental illnesses (SMI) that are part of a psychosis continuum, and dysregulated innate immune responses have been suggested to be involved in their ...

    • Increased incidence of inflammatory bowel disease on etanercept in juvenile idiopathic arthritis regardless of concomitant methotrexate use 

      van Straalen, Joeri W.; Krol, Roline; Giancane, Gabriella; Panaviene, Violeta; Ailioaie, Laura Marinela; Dolezalova, Pavla; Cattalini, Marco; Susic, Gordana; Sztajnbok, Flavio; Maritsi, Despoina; Constantin, Tamas; Sawhney, Sujata; Rygg, Marite; Oliveira, Sheila K.; Nordal, Ellen Berit; Saad-Magalhaes, C; Rubio-Perez, Nadina; Jelusic, Marija; de Roock, Sytze; Wulffraat, Nico; Ruperto, Nicolino; Swart, Joost Frans; International Trials Org, Paediatric Rheumatology (Peer reviewed; Journal article, 2021)
      Objectives: To describe risk factors for inflammatory bowel disease (IBD) development in a cohort of children with juvenile idiopathic arthritis (JIA). Methods: JIA patients who developed IBD were identified from the ...

    • Increased levels of microRNA-320 in blood serum and plasma is associated with imminent and advanced lung cancer 

      Nøst, Therese Haugdahl; Skogholt, Anne Heidi; Urbarova, Ilona Halva; Mjelle, Robin; Paulsen, Erna-Elise; Dønnem, Tom; Andersen, Sigve; Markaki, Maria; Røe, Oluf Dimitri; Johansson, Mikael; Johansson, Mattias; Grønberg, Bjørn Henning; Sandanger, Torkjel M; Sætrom, Pål (Peer reviewed; Journal article, 2022)
      Lung cancer (LC) incidence is increasing globally and altered levels of microRNAs (miRNAs) in blood may contribute to identification of individuals with LC. We identified miRNAs differentially expressed in peripheral blood ...

    • Increased long-term risk for hypertension in kidney donors – a retrospective cohort study 

      Haugen, Anders Johan Smedman; Hallan, Stein; Langberg, Nina Elisabeth Borthen; Dahle, Dag Olav; Pihlstrøm, Hege; Birkeland, Kåre I.; Reisæter, Anna Varberg; Midtvedt, Karsten; Hartmann, Anders; Holdaas, Hallvard; Mjøen, Geir (Peer reviewed; Journal article, 2020)
      Kidney donors may be at increased risk of end-stage renal disease and premature mortality. Elevated blood pressure after donation may contribute to the increased risks. In this cohort study, we have assessed long-term risk ...

    • Increased membrane Ca<sup>2+</sup> permeability drives astrocytic Ca<sup>2+</sup> dynamics during neuronal stimulation at excitatory synapses 

      Hjukse, Jarand Berg; Fernández de la Puebla, Mario; Vindedal, Gry Fluge; Sprengel, Rolf; Jensen, Vidar; Nagelhus, Erlend Arnulf; Tang, Wannan (Peer reviewed; Journal article, 2023)
      Astrocytes are intricately involved in the activity of neural circuits; however, their basic physiology of interacting with nearby neurons is not well established. Using two-photon imaging of neurons and astrocytes during ...

    • Increased mortality in hip fracture patients living alone: A NOREPOS study 

      Dahl, Cecilie; Holvik, Kristin; Meyer, Haakon E; Stigum, Hein; Solbakken, Siri Marie; Schei, Berit; Søgaard, Anne Johanne; Omsland, Tone Kristin (Peer reviewed; Journal article, 2021)
      Hip fracture is associated with excess mortality, persisting for many years after the fracture. Several factors may affect survival; however, the role of social support has been less studied. Living situation could be an ...

    • Increased Mortality in Young-Onset Parkinson's Disease 

      Hustad, Eldbjørg; Myklebust, Tor Åge; Gulati, Sasha; Aasly, Jan (Peer reviewed; Journal article, 2021)
      Objective Few studies have followed Parkinson’s disease (PD) patients from the time of diagnosis to the date of death. This study compared mortality in the Trondheim PD cohort to the general population, investigated causes ...

    • Increased Oxidative Stress Markers in Cerebrospinal Fluid from Healthy Subjects with Parkinson's Disease-Associated LRRK2 Gene Mutations 

      Loeffler, David A.; Klaver, Andrea C.; Coffey, Mary P.; Aasly, Jan; LeWitt, Peter A. (Peer reviewed; Journal article, 2017)
      Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene are the most frequent cause of inherited Parkinson’s disease (PD). The most common PD-associated LRRK2 mutation, G2019S, induces increased production of reactive ...

    • Increased p53 signaling impairs neural differentiation in HUWE1-promoted intellectual disabilities 

      Aprigliano, Rossana; Aksu, Merdane Ezgi; Bradamante, Stefano; Mihaljevic, Boris; Wang, Wei; Rian, Kristin; Montaldo, Nicola Pietro; Grooms, Kayla; Martin, Sarah; Bordin, Diana Lilian; Bosshard, Matthias; Peng, Yunhui; Alexov, Emil; Skinner, Cindy; Liabakk, Nina-Beate; Sullivan, Gareth; Bjørås, Magnar; Schwartz, Charles; van Loon, Barbara (Peer reviewed; Journal article, 2021)
      Essential E3 ubiquitin ligase HUWE1 (HECT, UBA, and WWE domain containing 1) regulates key factors, such as p53. Although mutations in HUWE1 cause heterogenous neurodevelopmental X-linked intellectual disabilities (XLIDs), ...

    • Increased risk of ischaemic heart disease after kidney donation 

      Haugen, Anders Johan Smedman; Hallan, Stein; Langberg, Nina Elisabeth Borthen; Dahle, Dag Olav; Pihlstrøm, Hege K.; Birkeland, Kåre Inge; Reisæter, Anna Varberg; Midtvedt, Karsten; Hartmann, Anders; Holdaas, Hallvard; Mjøen, Geir (Peer reviewed; Journal article, 2021)
      Background Previous reports suggest increased risk of hypertension and cardiovascular mortality after kidney donation. In this study we investigate the occurrence of ischaemic heart disease and cerebrovascular disease, ...

    • Increased risk of ischaemic heart disease after kidney donation 

      Haugen, Anders Johan Smedman; Hallan, Stein; Langberg, Nina Elisabeth Borthen; Dahle, Dag Olav; Pihlstrøm, Hege K.; Birkeland, Kåre Inge; Reisæter, Anna Varberg; Midtvedt, Karsten; Hartmann, Anders; Holdaas, Hallvard; Mjøen, Geir (Peer reviewed; Journal article, 2022)
      Background - Previous reports suggest increased risk of hypertension and cardiovascular mortality after kidney donation. In this study we investigate the occurrence of ischaemic heart disease and cerebrovascular disease, ...

    • Increasing but levelling out risk of revision due to infection after total hip arthroplasty: a study on 108,854 primary THAs in the Norwegian Arthroplasty Register from 2005 to 2019 

      Dale, Håvard; Høvding, Pål; Tveit, Sindre M.; Graff, Julie B.; Lutro, Olav; Schrama, Johannes Cornelis; Wik, Tina Strømdal; Skråmm, Inge; Westberg, Marianne; Fenstad, Anne Marie; Hallan, Geir; Engesæter, Lars B.; Furnes, Ove (Peer reviewed; Journal article, 2020)
      Background and purpose — Focus on prevention, surveillance, and treatment of infection after total hip arthroplasty (THA) in the last decade has resulted in new knowledge and guidelines. Previous publications have suggested ...

    • Increasing Incidences and Clonal Diversity of Methicillin-Resistant Staphylococcus aureus in the Nordic Countries - Results From the Nordic MRSA Surveillance 

      Petersen, Andreas; Larssen, Kjersti Wik; Gran, Frode Width; Enger, Hege; Hæggman, Sara; Mäkitalo, Barbro; Haraldsson, Gunnsteinn; Lindholm, Laura; Vuopio, Jaana; Henius, Anna Emilie; Nielsen, Jens; Larsen, Anders Rhod (Peer reviewed; Journal article, 2021)
      Methicillin-resistant Staphylococcus aureus (MRSA) is notifiable in Denmark, Finland, Iceland, Norway and Sweden. The prevalence of MRSA in this region has been low for many years, but all five countries experience increasing ...

    • Indexing cardiac volumes for peak oxygen uptake to improve differentiation of physiological and pathological remodeling: from elite athletes to heart failure patients 

      Letnes, Jon Magne; Nes, Bjarne Martens; Langlo, Knut Asbjørn Rise; Lundgren, Kari Margrethe; Skovereng, Knut; Sandbakk, Øyvind Bucher; Wisløff, Ulrik; Dalen, Håvard; Aksetøy, Inger-Lise Aamot (Peer reviewed; Journal article, 2023)
      Aims Cardiovascular structures adapt to meet metabolic demands, but current methodology for indexing by body size does not accurately reflect such variations. Therefore, we aimed to investigate how left ventricular ...

    • An individual participant data analysis of prospective cohort studies on the association between subclinical thyroid dysfunction and depressive symptoms 

      Wildisen, Lea; Del Giovane, Cinzia; Moutzouri, Elisavet; Beglinger, Shanthi; Syrogiannouli, Lamprini; Collet, Tinh-Hai; Cappola, Anne R.; Åsvold, Bjørn Olav; Bakker, Stephan J.L.; Yeap, Bu B.; Almeida, Osvaldo P.; Ceresini, Graziano; Dullaart, Robin P. F.; Ferrucci, Luigi; Grabe, Hans J.; Jukema, J. Wouter; Nauck, Matthias; Trompet, Stella; Völzke, Henry; Westendorp, Rudi G.J.; Gussekloo, Jacobijn; Klöppel, Stefan; Aujesky, Drahomir; Bauer, Douglas C.; Peeters, Robin P.; Feller, Martin; Rodondi, Nicolas (Peer reviewed; Journal article, 2020)
      In subclinical hypothyroidism, the presence of depressive symptoms is often a reason for starting levothyroxine treatment. However, data are conflicting on the association between subclinical thyroid dysfunction and ...

    • Individual Variation in Adaptive Immune Responses and Risk of Hip Fracture-A NOREPOS Population-Based Cohort Study 

      Dahl, Jesper; Holvik, Kristin; Heldal, Einar; Grimnes, Guri; Hoff, Mari; Finnes, Trine; Apalset, Ellen Margrete; Meyer, Haakon E (Journal article; Peer reviewed, 2020)
      Immune‐mediated bone loss significantly impacts fracture risk in patients with autoimmune disease, but to what extent individual variations in immune responses affect fracture risk on a population level is unknown. To ...

    • Induction of labor in breech presentations - a retrospective cohort study 

      Welle-Strand, Johanne Augusta Horn; Tappert, Christian; Eggebø, Torbjørn Moe (Peer reviewed; Journal article, 2021)
      Introduction There is limited evidence on the safety and outcome of induction of breech labor. In this study, we aimed to compare the outcomes of spontaneous and induced breech deliveries and to describe variations in ...

    • Induction of labor in twin pregnancies – A retrospective cohort study 

      Mikaelsen, Ingrid; Johansen, Anine Nikoline; Tappert, Christian; Eggebø, Torbjørn Moe (Journal article; Peer reviewed, 2022)

    • The inflammasome components NLRP3 and ASC act in concert with IRGM to rearrange the golgi apparatus during hepatitis C virus infection 

      Daussy, Coralie F.; Monard, Sarah C.; Guy, Coralie; Muñoz-González, Sara; Chazal, Maxime; Anthonsen, Marit Walbye; Jouvenet, Nolwenn; Henry, Thomas; Dreux, Marlène; Meurs, Eliane F.; Hansen, Marianne Dore (Peer reviewed; Journal article, 2021)
      Hepatitis C virus (HCV) infection triggers Golgi fragmentation through the Golgi-resident protein immunity-related GTPase M (IRGM). Here, we report the roles of NLRP3 (NOD-, LRR- and pyrin domain-containing protein 3) and ...