Now showing items 619-638 of 1478

    • Hermansky-Pudlak syndrome type 2 manifests with fibrosing lung disease early in childhood 

      Hengst, Meike; Naehrlich, Lutz; Mahavadi, Poornima; Grosse-Onnebrink, Joerg; Terheggen-Lagro, Suzanne; Skanke, Lars Høsøien; Schuch, Luise A; Brasch, Frank; Guenther, Andreas; Reu, Simone; Ley-Zaporozhan, Julia; Griese, Matthias (Peer reviewed; Journal article, 2018)
      Background: Hermansky-Pudlak syndrome (HPS), a hereditary multisystem disorder with oculocutaneous albinism, may be caused by mutations in one of at least 10 separate genes. The HPS-2 subtype is distinguished by the presence ...
    • Hexadirectional coding of visual space in human entorhinal cortex 

      Nau, Matthias; Schröder, Tobias Navarro; Bellmund, Jacob Lukas Sarid; Doeller, Christian Fritz Andreas (Journal article; Peer reviewed, 2018)
      Entorhinal grid cells map the local environment, but their involvement beyond spatial navigation remains elusive. We examined human functional MRI responses during a highly controlled visual tracking task and show that ...
    • High arterial oxygen levels and supplemental oxygen administration in traumatic brain injury: insights from CENTER-TBI and OzENTER-TBI 

      Petrosino, Matteo; Rezoagli, Emanuele; Rebora, Paola; Menon, David K.; Mondello, Stefania; Cooper, D. James; Maas, Andrew I. R.; Wiegers, Eveline J. A.; Stefania, Galimberti; Citerio, Giuseppe; Nada, Andelic; Andreassen, Lasse; Vik, Anne; Anke, Audny Gabriele Wagner; Frisvold, Shirin; Skandsen, Toril; Helseth, Eirik; Røe, Cecilie; Røise, Olav (Peer reviewed; Journal article, 2022)
      Purpose The effect of high arterial oxygen levels and supplemental oxygen administration on outcomes in traumatic brain injury (TBI) is debated, and data from large cohorts of TBI patients are limited. We investigated ...
    • High concentrations of soluble endoglin can inhibit BMP9 signaling in non-endothelial cells 

      Andersson-Rusch, Clara Leticia; Liu, Bin; Quist-Løkken, Ingrid; Upton, Paul D.; Olsen, Oddrun Elise; Hella, Hanne; Yang, Xudong; Tong, Zhen; Morrell, Nicholas W.; Holien, Toril; Li, Wei (Peer reviewed; Journal article, 2023)
      Endoglin (ENG) is a single-pass transmembrane protein highly expressed on vascular endothelial cells, although low expression levels can be detected in many other cell types. Its extracellular domain can be found in ...
    • High incidence and prevalence of MS in Møre and Romsdal County, Norway, 1950–2018 

      Willumsen, Johannes Sverre; Aarseth, Jan Harald; Myhr, Kjell-Morten; Midgard, Rune (Peer reviewed; Journal article, 2020)
      Objective To determine prevalence and longitudinal trends in incidence of MS in Møre and Romsdal County, Western Norway, from 1950 to 2018. Methods Retrospective longitudinal population-based observational study. All ...
    • High Levels of Complement Activating Enzyme MASP-2 Are Associated With the Risk of Future Incident Venous Thromboembolism 

      Damoah, Christabel Esi; Snir, Omri; Hindberg, Kristian Dalsbø; Garred, Peter; Ludviksen, Judith K; Brækkan, Sigrid Kufaas; Morelli, Vania Maris; Mollnes, Tom Eirik; Hansen, John Bjarne (Peer reviewed; Journal article, 2022)
      Background: Experimental studies have shown that the complement activating enzyme MASP-2 (mannose-binding lectin associated serine protease 2) exhibits a thrombin-like activity and that inhibition of MASP-2 protects ...
    • High levels of discordant antimicrobial therapy in hospital-acquired bloodstream infections is associated with increased mortality in an intensive care, low antimicrobial resistance setting 

      Waagsbø, Bjørn; Stuve, Nora; Afset, Jan Egil; Klepstad, Pål; Mo, Skule; Heggelund, Lars; Damås, Jan Kristian (Peer reviewed; Journal article, 2022)
      Background Bloodstream infections (BSI) occur frequently and are associated with severe outcomes. In this study we aimed to investigate proportions of patients that received discordant empirical antimicrobial therapy and ...
    • High neuroticism is associated with reduced negative affect following sleep deprivation 

      Saksvik-Lehouillier, Ingvild; Langvik, Eva; Saksvik, Simen Berg; Kallestad, Håvard; Follesø, Hanna Størksen; Austad, Sigrun Borgen; Dahlberg, Johanna; Ringen, Heidi; Tanum, Tiril Kristine; Sørengaard, Torhild Anita; Karlsen, Håvard Rudi; Smedbøl, Trine; Olsen, Alexander (Peer reviewed; Journal article, 2021)
      The aim was to investigate how neuroticism moderates the affective consequences of personalized mild-moderate partial sleep deprivation. A total of 52 healthy subjects aged 18–35 years completed the NEO PI-3 at baseline, ...
    • High prevalence of vertebral fractures and low trabecular bone score in patients with fragility fractures: A cross-sectional sub-study of NoFRACT 

      Borgen, Tove Tveitan; Bjørnerem, Åshild; Solberg, Lene Bergendal; Andreasen, Camilla; Brunborg, Cathrine; Stenbro, May-Britt; Hübschle, Lars Michael; Froholdt, Anne; Figved, Wender; Apalset, Ellen M; Gjertsen, Jan-Erik; Basso, Trude; Lund, Ida; Hansen, Ann Kristin; Stutzer, Jens-Meinhard; Dahl, Cecilie; Omsland, Tone Kristin; Nordsletten, Lars; Frihagen, Frede Jon; Eriksen, Erik Fink (Peer reviewed; Journal article, 2019)
      Purpose - Norway has among the highest incidence rates of fractures in the world. Vertebral fracture assessment (VFA) and trabecular bone score (TBS) provide information about fracture risk, but their importance have not ...
    • High-density lipoprotein subfractions: Much ado about nothing or clinically important? 

      Lappegård, Knut Tore; Kjellmo, Christian Abendstein; Hovland, Anders (Peer reviewed; Journal article, 2021)
      High-density lipoproteins (HDL) are a heterogenous group of plasma molecules with a large variety in composition. There is a wide specter in lipid content and the number of different proteins that has been associated with ...
    • High-intensity exergaming for improved cardiorespiratory fitness: A randomised, controlled trial 

      Berg, Jonathan; Haugen, Guri; Wang, Alf Inge; Moholdt, Trine (Peer reviewed; Journal article, 2021)
      Exergaming has been proposed as a promising alternative to traditional endurance training since many experience exergaming as more enjoyable. Therefore, the aim of this trial was to determine the exergaming-induced effect ...
    • High-sensitivity C-reactive protein is related to age and gender in an acute psychiatric inpatient population 

      Sakai, Yuki; Larsen, Jeanette Brun; Reitan, Solveig Merete Klæbo (Journal article; Peer reviewed, 2022)
      Increased levels of high-sensitivity C-reactive protein (hsCRP) is associated with several psychiatric disorders. Demographic factors such as age and gender might affect this association, but the results are conflicting. ...
    • Higher vitamin B12 levels in neurodevelopmental disorders than in healthy controls and schizophrenia A comparison among participants between 2 and 53 years 

      Hope, Sigrun; Nærland, Terje; Høyland, Anne Lise; Torske, Tonje; Malt, Eva; Abrahamsen, Tore G; Nerhus, Mari; Wedervang-Resell, Kirsten; Lonning, Vera Louise Hiorth; Johannessen, Jarle; Steen, Nils Eiel; Agartz, Ingrid; Stenberg, Nina; Hundhausen, Thomas Eckhard; Mørkrid, Lars; Andreassen, Ole Andreas (Peer reviewed; Journal article, 2020)
      Recent studies suggest that both high and low levels of vitamin B12 (vitB12) may have negative health impacts. We measured VitB12 in patients with the Neurodevelopmental disorders (ND) (n = 222), comprised of Autism Spectrum ...
    • Highlight selection of radiochemistry and radiopharmacy developments by editorial board 

      Aime, Silvio; Al-Qahtani, Mohammed; Behe, Martin; Bormans, Guy; Carlucci, Giuseppe; DaSilva, Jean N.; Decristoforo, Clemens; Duatti, Adriano; Elsinga, Philip H.; Kopka, Klaus; Li, Xiang-Guo; Liu, Zhibo; Mach, Robert H.; Middel, Oskar; Passchier, Jan; Patt, Marianne; Penuelas, Ivan; Rey, Ana; Scott, Peter J. H.; Todde, Sergio; Toyohara, Jun; Vugts, Danielle; Yang, Zhi (Peer reviewed; Journal article, 2021)
      Background: The Editorial Board of EJNMMI Radiopharmacy and Chemistry releases a biyearly highlight commentary to update the readership on trends in the field of radiopharmaceutical development. Results: This commentary ...
    • Highly expressed genes in multiple myeloma cells – what can they tell us about the disease? 

      Børset, Magne; Elsaadi, Samah; Vandsemb, Esten Nymoen; Hess, Eli Svorkdal; Steiro, Ida Johnsen; Cócera Fernández, Miguel; Sponaas, Anne-Marit; Abdollahi, Pegah (Peer reviewed; Journal article, 2022)
      Cancer cells can convert proto-oncoproteins into oncoproteins by increasing the expression of genes that are oncogenic when expressed at high levels. Such genes can promote oncogenesis without being mutated. To find ...
    • Highly variable effect of sonication to dislodge biofilm-embedded Staphylococcus epidermidis directly quantified by epifluorescence microscopy: an in vitro model study 

      Sandbakken, Erik Thorvaldsen; Witsø, Eivind; Sporsheim, Bjørnar; Egeberg, Kjartan Wøllo; Foss, Olav A.; Hoang, Linh; Bjerkan, Geir; Løseth, Kirsti; Bergh, Kåre (Peer reviewed; Journal article, 2020)
      Background In cases of prosthetic joint infections, culture of sonication fluid can supplement culture of harvested tissue samples for correct microbial diagnosis. However, discrepant results regarding the increased ...
    • The histological representativeness of glioblastoma tissue samples 

      Mikkelsen, Vilde Elisabeth; Solheim, Ole; Salvesen, Øyvind; Torp, Sverre Helge (Peer reviewed; Journal article, 2020)
      Background Glioblastomas (GBMs) are known for having a vastly heterogenous histopathology. Several studies have shown that GBMs can be histologically undergraded due to sampling errors of small tissue samples. We sought ...
    • Hjemmefødsler innebærer unødvendig risiko 

      Nordseth, Trond (Peer reviewed; Journal article, 2019)
    • Hjerneslag i Norge 2015-16 - behandling og resultater 

      Varmdal, Torunn; Indredavik, Bent; Phan, Ailan; Fjærtoft, Hild (Peer reviewed; Journal article, 2020)
      BAKGRUNN I Norge er hjerneslagbehandlingen desentralisert, og pasienter med hjerneslag blir behandlet ved 50 sykehus. Vi har kartlagt slagbehandlingen ved sykehusene og sammenstilt dette med data fra Norsk hjerneslagregister ...
    • Holding on to the indispensable medication - A grounded theory on medication use from the perspective of persons with medication overuse headache 

      Jonsson, Pernilla; Jakobsson, Annika; Hensing, Gunnel; Linde, Mattias; Moore, Crystal Dea; Hedenrud, Tove (Journal article; Peer reviewed, 2013)
      Background Medication overuse headache (MOH) is a chronic headache disorder, caused by overuse of acute medication. To date, it remains unclear why some people overuse these medications. The aim of this qualitative study ...