Blar i Publikasjoner fra Cristin - St. Olavs hospital på tittel
Viser treff 1484-1503 av 1611
-
Tocilizumab increases citrullinated histone 3 in non-ST segment elevation myocardial infarction
(Peer reviewed; Journal article, 2021)Objective Beyond reducing inflammation and troponin T (TnT) release, the interleukin-6 receptor antagonist tocilizumab reduces neutrophil counts in patients with non-ST segment elevation myocardial infarction (NSTEMI). It ... -
Tools for optimising pharmacotherapy in psychiatry (therapeutic drug monitoring, molecular brain imaging and pharmacogenetic tests): focus on antidepressants
(Peer reviewed; Journal article, 2021)Objectives: More than 40 drugs are available to treat affective disorders. Individual selection of the optimal drug and dose is required to attain the highest possible efficacy and acceptable tolerability for every patient. ... -
Toward a global and reproducible science for brain imaging in neurotrauma: the ENIGMA adult moderate/severe traumatic brain injury working group
(Peer reviewed; Journal article, 2020)The global burden of mortality and morbidity caused by traumatic brain injury (TBI) is significant, and the heterogeneity of TBI patients and the relatively small sample sizes of most current neuroimaging studies is a major ... -
Towards human-level performance on automatic pose estimation of infant spontaneous movements
(Peer reviewed; Journal article, 2021)Assessment of spontaneous movements can predict the long-term developmental disorders in high-risk infants. In order to develop algorithms for automated prediction of later disorders, highly precise localization of segments ... -
Tracheal cancer: a rare and deadly but potentially curable disease that also affects younger people
(Peer reviewed; Journal article, 2023)OBJECTIVES The incidence of tracheal cancer is low, few clinicians get much experience and the awareness may be low. Recent data on the treatment and outcome are limited. The aim of the present study was to present ... -
Tracheal intubation in traumatic brain injury: a multicentre prospective observational study
(Peer reviewed; Journal article, 2020)Background: We aimed to study the associations between pre- and in-hospital tracheal intubation and outcomes in traumatic brain injury (TBI), and whether the association varied according to injury severity. Methods: Data ... -
Tracking impact of interstitial lung disease in systemic sclerosis in a complete nationwide cohort
(Journal article; Peer reviewed, 2019)Rationale: Interstitial lung disease (ILD) represents a major challenge in systemic sclerosis (SSc), but there are no precise, population-based data on its overall impact, limiting opportunities for screening and management ... -
Tracking-based mitral annular plane systolic excursion (MAPSE) measurement using deep learning in B-mode ultrasound
(Peer reviewed; Journal article, 2022)Mitral annular plane systolic excursion (MAPSE) is an important measure of left ventricular function. Current clinical practice is to measure it manually using M-mode ultrasound imaging which has several disadvantages such ... -
Trajectories of Pain in Patients Undergoing Lung Cancer Surgery: A Longitudinal Prospective Study.
(Peer reviewed; Journal article, 2019)Context Lung cancer surgery is among the surgical procedures associated with the highest prevalence of pain, but prospective longitudinal studies after the pain trajectory are scarce. Objectives We aimed to describe the ... -
Trajectories of Persistent Postconcussion Symptoms and Factors Associated With Symptom Reporting After Mild Traumatic Brain Injury
(Peer reviewed; Journal article, 2021)Objective To examine the trajectories of persistent postconcussion symptoms (PPCS) after mild traumatic brain injury (MTBI) and to investigate which injury-related and personal factors are associated with symptom reporting. ... -
Trajectories of response in schizophrenia-spectrum disorders: A one-year prospective cohort study of antipsychotic effectiveness
(Journal article; Peer reviewed, 2022)BACKGROUND: Antipsychotic drugs remain the mainstay of schizophrenia treatment; however, their effectiveness has been questioned, and it is not possible to predict the response to a specific antipsychotic drug in an ... -
Trajectory of cardiac troponin T following moderate-to-severe COVID-19 and the association with cardiac abnormalities
(Journal article; Peer reviewed, 2024)Background COVID-19 has been associated with cardiac troponin T (cTnT) elevations and changes in cardiac structure and function, but the link between cardiac dysfunction and high-sensitive cardiac troponin T (hs-cTnT) in ... -
Trajectory of health-related quality of life during the last year of life in patients with advanced non-small–cell lung cancer
(Peer reviewed; Journal article, 2022)Background The aims of this study were to assess the trajectory of health-related quality of life (HRQOL) during the last year of life in patients with advanced non-small–cell lung cancer (NSCLC) and to explore when and ... -
Trans-fatty acids and survival in renal transplantation
(Journal article; Peer reviewed, 2018)Objective High consumption of trans-fatty acids (TFAs) is associated with increased mortality. Design and methods Observational cohort study of 1.988 Norwegian renal transplant recipients with a median follow-up time ... -
Transcriptomic Profiling of Collagenous Colitis Identifies Hallmarks of Nondestructive Inflammatory Bowel Disease
(Peer reviewed; Journal article, 2021)Background and aims: The pathophysiology of the inflammatory bowel disease collagenous colitis (CC) is poorly described. Our aim was to use RNA sequencing of mucosal samples from patients with active CC, CC in remission, ... -
Transfer of cetirizine/levocetirizine into human breast milk and estimation of drug exposure to infants through breastfeeding: A human lactation study from the ConcePTION project
(Peer reviewed; Journal article, 2023)Data on drug transfer into human breast milk are sparse. This study aimed to quantify concentrations of cetirizine and levocetirizine in breast milk and to estimate drug exposure to infants. Breastfeeding women at least ... -
Transfusion of red blood cells in coronary surgery: is there an effect on long-term mortality when adjusting for risk factors and postoperative complications?
(Peer reviewed; Journal article, 2017)OBJECTIVES The aim of this study was to compare long-term mortality in patients undergoing primary isolated coronary artery bypass grafting who received ≥1 units of red blood cells (RBCs) or no RBCs. We hypothesized that ... -
Transfusion practice in Central Norway - a regional cohort study in patients suffering from major haemorrhage
(Peer reviewed; Journal article, 2024)Background: In patients with major hemorrhage, balanced transfusions and limited crystalloid use is recommended in both civilian and military guidelines. This transfusion strategy is often applied in the non-trauma patient ... -
Transient effect of melatonin treatment after neonatal hypoxic-ischemic brain injury in rats
(Journal article; Peer reviewed, 2019)Melatonin has potential neuroprotective capabilities after neonatal hypoxia-ischemia (HI), but long-term effects have not been investigated. We hypothesized that melatonin treatment directly after HI could protect against ... -
Transient global amnesia: 7 Tesla MRI reveals more hippocampal lesions with diffusion restriction compared to 1.5 and 3 Tesla MRI
(Journal article; Peer reviewed, 2022)