Blar i Publikasjoner fra Cristin - St. Olavs hospital på tittel
Viser treff 634-653 av 1611
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Genome-wide association study of intracranial aneurysms identifies 17 risk loci and genetic overlap with clinical risk factors
(Peer reviewed; Journal article, 2020)Rupture of an intracranial aneurysm leads to subarachnoid hemorrhage, a severe type of stroke. To discover new risk loci and the genetic architecture of intracranial aneurysms, we performed a cross-ancestry, genome-wide ... -
Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth
(Peer reviewed; Journal article, 2023)A well-functioning placenta is essential for fetal and maternal health throughout pregnancy. Using placental weight as a proxy for placental growth, we report genome-wide association analyses in the fetal (n = 65,405), ... -
A genome-wide association study provides insights into the genetic etiology of 57 essential and non-essential trace elements in humans
(Journal article; Peer reviewed, 2024)Trace elements are important for human health but may exert toxic or adverse effects. Mechanisms of uptake, distribution, metabolism, and excretion are partly under genetic control but have not yet been extensively mapped. ... -
Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk
(Journal article; Peer reviewed, 2019)Alzheimer’s disease (AD) is highly heritable and recent studies have identified over 20 disease-associated genomic loci. Yet these only explain a small proportion of the genetic variance, indicating that undiscovered loci ... -
Genome-wide meta-analysis of iron status biomarkers and the effect of iron on all-cause mortality in HUNT
(Peer reviewed; Journal article, 2022)Iron is essential for many biological processes, but iron levels must be tightly regulated to avoid harmful effects of both iron deficiency and overload. Here, we perform genome-wide association studies on four iron-related ... -
Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders.
(Peer reviewed; Journal article, 2019)Genetic influences on psychiatric disorders transcend diagnostic boundaries, suggesting substantial pleiotropy of contributing loci. However, the nature and mechanisms of these pleiotropic effects remain unclear. We performed ... -
Geographic and socioeconomic inequities in cesarean delivery rates at the district level in Madhya Pradesh, India: A secondary analysis of the national family health survey-5
(Peer reviewed; Journal article, 2023)Background In India, caesarean delivery (CD) accounts for 17% of the births, of which 41% occur in private facilities. However, areas to CD in rural areas are limited, particularly for the poor populations. Little information ... -
Geriatric assessment with management for older patients with cancer receiving radiotherapy: a cluster-randomised controlled pilot study
(Journal article; Peer reviewed, 2024)Background: Geriatric assessment and management (GAM) improve outcomes in older patients with cancer treated with surgery or chemotherapy. It is unclear whether GAM may provide better function and quality of life (QoL), ... -
Germline pathogenic variants in patients with high-grade gastroenteropancreatic neuroendocrine neoplasms
(Peer reviewed; Journal article, 2023)High-grade gastroenteropancreatic (HG-GEP) neuroendocrine neoplasms (NENs) are highly aggressive cancers. The molecular etiology of these tumors remains unclear, and the prevalence of pathogenic germline variants in patients ... -
Gestational Age, Parent Education, and Education in Adulthood
(Journal article; Peer reviewed, 2021)BACKGROUND: Adults born preterm (<37 weeks) have lower educational attainment than those born term. Whether this relationship is modified by family factors such as socioeconomic background is, however, less well known. We ... -
Gestational weight gain outside the Institute of Medicine recommendations and adverse pregnancy outcomes: analysis using individual participant data from randomised trials
(Journal article; Peer reviewed, 2019)Background:High Body Mass Index (BMI) and gestational weight gain (GWG) affect an increasing number ofpregnancies. The Institute of Medicine (IOM) has issued recommendations on the optimal GWG for womenaccording to their ... -
Gir ACE-hemmere og angiotensinreseptorantagonister økt risiko for alvorlig covid-19?
(Peer reviewed; Journal article, 2020)Hypertensjon og diabetes mellitus er risikofaktorer for alvorlig covid-19. Det er blitt reist spørsmål om hvorvidt denne assosiasjonen er relatert til bruk av ACE-hemmere og angiotensin II-reseptorblokkere. -
Gjenvinning av mobilitet etter hoftebrudd – en prospektiv kohortestudie
(Peer reviewed; Journal article, 2020)Hensikt: Å undersøke hva som karakteriserer eldre med hoftebrudd som ikke gjenvinner mobilitet, samt å beskrive mengden fysioterapi denne gruppen mottar det første året etter hoftebrudd. Design: Prospektiv kohortestudie. ... -
Glioblastom hos voksne
(Peer reviewed; Journal article, 2023)lioblastom er den vanligste formen for primær hjernekreft hos voksne, og sykdommen har en alvorlig prognose. Selv om det er gjort store fremskritt i molekylær karakteristikk, har det ikke vært større gjennombrudd i ... -
Global longitudinal strain is a more reproducible measure of left ventricular function than ejection fraction regardless of echocardiographic training
(Peer reviewed; Journal article, 2019)Background: Left ventricular ejection fraction (LVEF) is an established method for evaluation of left ventricular (LV)systolic function. Global longitudinal strain (GLS) by speckle tracking echocardiography seems to be an ... -
The global prevalence of headache: an update, with analysis of the influences of methodological factors on prevalence estimates
(Peer reviewed; Journal article, 2022)Background According to the Global Burden of Disease (GBD) study, headache disorders are among the most prevalent and disabling conditions worldwide. GBD builds on epidemiological studies (published and unpublished) ... -
Global variation in anastomosis and end colostomy formation following left-sided colorectal resection
(Peer reviewed; Journal article, 2019)Background: End colostomy rates following colorectal resection vary across institutions in high-income settings, being influenced by patient, disease, surgeon and system factors. This study aimed to assess global variation ... -
Glucoregulatory Properties of a Protein Hydrolysate from Atlantic Salmon (Salmo salar): Preliminary Characterization and Evaluation of DPP-IV Inhibition and Direct Glucose Uptake In Vitro
(Journal article; Peer reviewed, 2024)Metabolic disorders are increasingly prevalent conditions that manifest pathophysiologically along a continuum. Among reported metabolic risk factors, elevated fasting serum glucose (FSG) levels have shown the most substantial ... -
Growth during infancy and early childhood in children with cerebral palsy: a population-based study
(Peer reviewed; Journal article, 2016)Aim To describe growth in infancy and early childhood in children with cerebral palsy (CP). Method One hundred and four children with CP born at minimum 36 weeks' gestation in 2002 to 2010 were included. Prospectively ... -
Guideline-Recommended Time Less Than 90 Minutes From ECG to Primary Percutaneous Coronary Intervention for ST-Segment–Elevation Myocardial Infarction Is Associated with Major Survival Benefits, Especially in Octogenarians: A Contemporary Report in 11 226 Patients from NORIC
(Peer reviewed; Journal article, 2022)Background - Using contemporary data from NORIC (Norwegian Registry of Invasive Cardiology) we investigated the predictive value of patient age and time from ECG diagnosis to sheath insertion (ECG‐2‐sheath) in primary ...