• Thromboembolic Events During Treatment with Cisplatin-based Chemotherapy in Metastatic Testicular Germ-cell Cancer 2000–2014: A Population-based Cohort Study 

      Haugnes, Hege S.; Negaard, Helene F.; Negaard, Helene Francisca Stigter; Jensvoll, Hilde; Wilsgaard, Tom; Tandstad, Torgrim; Solberg, Arne (Peer reviewed; Journal article, 2021)
      Background Cisplatin-based chemotherapy (CBCT) in testicular cancer (TC) is associated with elevated venous thromboembolism (VTE) risk, but trials evaluating the safety and efficacy of thromboprophylaxis are lacking. ...
    • Thrombosis and bleedings in a cohort of cancer patients treated with apixaban for venous thromboembolism 

      Hannevik, Trine-Lise; Brekke, Jorunn; Enden, Tone Rønnaug; Frøen, Hege; Ahmed, Herish; Jacobsen, Eva-Marie; Quist-Paulsen, Petter; Porojnicu, Alina Carmen; Ree, Anne Hansen; Torfoss, Dag; Velle, Elin Osvik; Wik, Hilde Skuterud; Ghanima, Waleed Khalid; Sandset, Per Morten; Dahm, Anders Erik A (Peer reviewed; Journal article, 2020)
      Introduction: The direct oral anti-coagulants (DOAC) edoxaban and rivaroxaban are suggested treatment alternatives for cancer-associated venous thromboembolism (VTE) together with low molecular-weight heparins. New studies ...
    • Time to classify tumours of the stomach and the kidneys according to cell of origin 

      Waldum, Helge; Mjønes, Patricia (Peer reviewed; Journal article, 2021)
      Abstract: Malignant tumours are traditionally classified according to their organ of origin and whether they are of epithelial (carcinomas) or mesenchymal (sarcomas) origin. By histological appearance the site of origin ...
    • Time to diagnosis in young onset alzheimer's disease: A population-based study from central Norway 

      Kvello-Alme, Marte; Bråthen, Geir; White, Linda Rosemary; Sando, Sigrid Botne (Peer reviewed; Journal article, 2021)
      Background: Young onset dementia is associated with a longer time to diagnosis compared to late onset dementia. Earlier publications have indicated that atypical presentation is a key contributing factor to the diagnostic ...
    • Time-dependent effects on circulating cytokines in patients with LADA: A decrease in IL1-ra and IL-1 beta is associated with progressive disease 

      Hals, Ingrid Kathrin; Björklund, Anneli; Fleiner, Hanne Fiskvik; Grill, Valdemar Erik Robert (Peer reviewed; Journal article, 2022)
      Background - Cytokines and chemokines participate in autoimmune processes at cellular targets which include insulin-producing beta cells. To which extent such participation is reflected in the circulation has not been ...
    • Time-restricted eating and exercise training improve HbA1c and body composition in women with overweight/obesity: A randomized controlled trial 

      La Haganes, Kamilla; Silva Ruiz, Catalina Paz; Eyjolfsdottir, Svala Kristfridur; Steen, Sandra; Grindberg, Martine; Lydersen, Stian; Hawley, John A; Moholdt, Trine Tegdan (Peer reviewed; Journal article, 2022)
      Summary Diet modification and exercise training are primary lifestyle strategies for obesity management, but poor adherence rates limit their effectiveness. Time-restricted eating (TRE) and high-intensity interval training ...
    • The TLR4 adaptor TRAM controls the phagocytosis of Gram-negative bacteria by interacting with the Rab11-family interacting protein 2 

      Skjesol, Astrid; Yurchenko, Mariya; Bösl, Korbinian; Gravastrand, Caroline S.; Nilsen, Kaja Elisabeth; Grøvdal, Lene Melsæther; Agliano, Federica; Patane, Francesco; Lentini, Germana; Kim, Hera; Teti, Giuseppe; Sharma, Aditya Kumar; Kandasamy, Richard Kumaran; Sporsheim, Bjørnar; Starheim, Kristian K.; Golenbock, Douglas T.; Stenmark, Harald; McCaffrey, Mary; Espevik, Terje; Husebye, Harald (Peer reviewed; Journal article, 2019)
      Phagocytosis is a complex process that eliminates microbes and is performed by specialised cells such as macrophages. Toll-like receptor 4 (TLR4) is expressed on the surface of macrophages and recognizes Gram-negative ...
    • Tocilizumab increases citrullinated histone 3 in non-ST segment elevation myocardial infarction 

      Helseth, Ragnhild; Kleveland, Ola; Ueland, Thor; Wiseth, Rune; Damås, Jan Kristian; Broch, Kaspar; Michelsen, Annika Elisabet; Bendz, Bjørn; Gullestad, Lars; Aukrust, Pål; Seljeflot, Ingebjørg (Peer reviewed; Journal article, 2021)
      Objective Beyond reducing inflammation and troponin T (TnT) release, the interleukin-6 receptor antagonist tocilizumab reduces neutrophil counts in patients with non-ST segment elevation myocardial infarction (NSTEMI). It ...
    • Tools for optimising pharmacotherapy in psychiatry (therapeutic drug monitoring, molecular brain imaging and pharmacogenetic tests): focus on antidepressants 

      Eap, C.B.; Gründer, Gerhard; Baumann, P.; Ansermot, N.; Conca, A.; Corruble, E.; Crettol, S.; Dahl, Marja-Liisa; de Leon, Leon; Greiner, C.; Howes, Oliver D.; Kim, E.; Lanzenberger, R.; Meyer, J.H.; Moessner, R.; Mulder, H.; Müller, Daniel J.; Reis, Margareta; Riederer, P.; Ruhe, H.G.; Spigset, Olav; Spina, E.; Stegman, B.; Steimer, W.; Stingl, J.; Suzen, S.; Uchida, H.; Unterecker, S.; Vandenberghe, F.; Hiemke, C. (Peer reviewed; Journal article, 2021)
      Objectives: More than 40 drugs are available to treat affective disorders. Individual selection of the optimal drug and dose is required to attain the highest possible efficacy and acceptable tolerability for every patient. ...
    • Toward a global and reproducible science for brain imaging in neurotrauma: the ENIGMA adult moderate/severe traumatic brain injury working group 

      Olsen, Alexander; Babikian, Talin; Bigler, Erin D.; Caeyenberghs, Karen; Conde, Virginia; Dams-O’Connor, Kristen; Dobryakova, Ekaterina; Genova, Helen; Grafman, Jordan; Håberg, Asta; Heggland, Ingrid; Hellstrøm, Torgeir; Hodges, Cooper B.; Irimia, Andrei; Jha, Ruchira M.; Johnson, Paula K.; Koliatsos, Vassilis E.; Levin, Harvey; Li, Lucia M.; Lindsey, Hannah M.; Livny, Abigail; Løvstad, Marianne; Medaglia, John; Menon, David; Mondello, Stefania; Monti, Martin M.; Newcombe, Virginia F.J.; Petroni, Agustin; Ponsford, Jennie; Sharp, David; Spitz, Gershon; Westlye, Lars Tjelta; Thompson, Paul M.; Dennis, Emily L.; Tate, David; Wilde, Elisabeth A.; Hillary, Frank G. (Peer reviewed; Journal article, 2020)
      The global burden of mortality and morbidity caused by traumatic brain injury (TBI) is significant, and the heterogeneity of TBI patients and the relatively small sample sizes of most current neuroimaging studies is a major ...
    • Towards human-level performance on automatic pose estimation of infant spontaneous movements 

      Groos, Daniel; Adde, Lars; Støen, Ragnhild; Ramampiaro, Heri; Ihlen, Espen Alexander F. (Peer reviewed; Journal article, 2021)
      Assessment of spontaneous movements can predict the long-term developmental disorders in high-risk infants. In order to develop algorithms for automated prediction of later disorders, highly precise localization of segments ...
    • Tracheal cancer: a rare and deadly but potentially curable disease that also affects younger people 

      Nilssen, Yngvar; Solberg, Steinar; Brustugun, Odd Terje; Møller, Bjørn; Sundset, Arve; Wahl, Sissel Gyrid Freim; Helland, Åslaug (Peer reviewed; Journal article, 2023)
      OBJECTIVES The incidence of tracheal cancer is low, few clinicians get much experience and the awareness may be low. Recent data on the treatment and outcome are limited. The aim of the present study was to present ...
    • Tracheal intubation in traumatic brain injury: a multicentre prospective observational study 

      Gravesteijn, BY; Sewalt, Charlie; Nieboer, D.; Menon, David K.; Maas, Andrew I. R.; Lecky, Fiona E.; Klimek, Markus; Lingsma, Hester F; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Skandsen, Toril; Røe, Cecilie; Røise, Olav; Vik, Anne (Peer reviewed; Journal article, 2020)
      Background: We aimed to study the associations between pre- and in-hospital tracheal intubation and outcomes in traumatic brain injury (TBI), and whether the association varied according to injury severity. Methods: Data ...
    • Tracking impact of interstitial lung disease in systemic sclerosis in a complete nationwide cohort 

      Hoffmann-Vold, Anna-Maria; Fretheim, Håvard Halland; Halse, Anne-Kristine; Seip, Marit; Bitter, Helle; Wallenius, Marianne; Garen, Torhild Oddveig; Salberg, Anne; Brunborg, Cathrine; Midtvedt, Øyvind; Lund, May-Brith; Aaløkken, Trond M; Molberg, Øyvind (Journal article; Peer reviewed, 2019)
      Rationale: Interstitial lung disease (ILD) represents a major challenge in systemic sclerosis (SSc), but there are no precise, population-based data on its overall impact, limiting opportunities for screening and management ...
    • Tracking-based mitral annular plane systolic excursion (MAPSE) measurement using deep learning in B-mode ultrasound 

      Smistad, Erik; Østvik, Andreas; Grue, Jahn Frederik; Dalen, Håvard; Løvstakken, Lasse (Peer reviewed; Journal article, 2022)
      Mitral annular plane systolic excursion (MAPSE) is an important measure of left ventricular function. Current clinical practice is to measure it manually using M-mode ultrasound imaging which has several disadvantages such ...
    • Trajectories of Pain in Patients Undergoing Lung Cancer Surgery: A Longitudinal Prospective Study. 

      Gjeilo, Kari Hanne; Oksholm, Trine; Follestad, Turid; Wahba, Alexander; Rustøen, Tone (Peer reviewed; Journal article, 2019)
      Context Lung cancer surgery is among the surgical procedures associated with the highest prevalence of pain, but prospective longitudinal studies after the pain trajectory are scarce. Objectives We aimed to describe the ...
    • Trajectories of Persistent Postconcussion Symptoms and Factors Associated With Symptom Reporting After Mild Traumatic Brain Injury 

      Fordal, Linda; Stenberg, Jonas; Iverson, Grant L.; Saksvik, Simen Berg; Karaliute, Migle; Vik, Anne; Olsen, Alexander; Skandsen, Toril (Peer reviewed; Journal article, 2021)
      Objective To examine the trajectories of persistent postconcussion symptoms (PPCS) after mild traumatic brain injury (MTBI) and to investigate which injury-related and personal factors are associated with symptom reporting. ...
    • Trajectories of response in schizophrenia-spectrum disorders: A one-year prospective cohort study of antipsychotic effectiveness 

      Drosos, Petros; Johnsen, Erik; Bartz-Johannessen, Christoffer; Larsen, Tor Ketil; Reitan, Solveig Klæbo; Rettenbacher, Maria; Kroken, Rune Andreas (Journal article; Peer reviewed, 2022)
      BACKGROUND: Antipsychotic drugs remain the mainstay of schizophrenia treatment; however, their effectiveness has been questioned, and it is not possible to predict the response to a specific antipsychotic drug in an ...
    • Trajectory of health-related quality of life during the last year of life in patients with advanced non-small–cell lung cancer 

      Kristensen, Are Korsnes; Grønberg, Bjørn Henning; Fløtten, Øystein; Kaasa, Stein; Solheim, Tora S (Peer reviewed; Journal article, 2022)
      Background The aims of this study were to assess the trajectory of health-related quality of life (HRQOL) during the last year of life in patients with advanced non-small–cell lung cancer (NSCLC) and to explore when and ...
    • Trans-fatty acids and survival in renal transplantation 

      Chandra, Anupam; Svensson, My Hanna Sofia; Åsberg, Anders; Schmidt, Erik Berg; Bjerve, Kristian S; Jenssen, Trond Geir; Hartmann, Anders; Ueland, Thor; Eide, Ivar Anders (Journal article; Peer reviewed, 2018)
      Objective High consumption of trans-fatty acids (TFAs) is associated with increased mortality. Design and methods Observational cohort study of 1.988 Norwegian renal transplant recipients with a median follow-up time ...