Institutt for sirkulasjon og bildediagnostikk
Recent Submissions
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Rapid declines in systolic blood pressure are associated with an increase in pulse transit time
(Peer reviewed; Journal article, 2020)Background The correlation between pulse transit time and blood pressure has been proposed as a route to measure continuous non-invasive blood pressure. We investigated whether pulse transit time trends could model blood ... -
Cardiac arrest as a reportable condition: A cohort study of the first 6 years of the Norwegian out-of-hospital cardiac arrest registry
(Peer reviewed; Journal article, 2020)Objectives The Norwegian Cardiac Arrest Registry (NorCAR) was established in 2013 when cardiac arrest became a mandatory reportable condition. The aim of this cohort study is to describe how the world’s first mandatory, ... -
YKL-40 (Chitinase-3-Like Protein 1) Serum Levels in Aortic Stenosis
(Peer reviewed; Journal article, 2020)BACKGROUND: Identification of novel biomarkers could provide prognostic information and improve risk stratification in patients with aortic stenosis (AS). YKL-40 (chitinase-3-like protein 1), a protein involved in ... -
Circulating and Adipose Tissue miRNAs in Women With Polycystic Ovary Syndrome and Responses to High-Intensity Interval Training
(Peer reviewed; Journal article, 2020)MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression post-transcriptionally. In women with polycystic ovary syndrome (PCOS), several miRNAs are differentially expressed compared to women without PCOS, ... -
Plasma membrane damage causes NLRP3 activation and pyroptosis during Mycobacterium tuberculosis infection
(Peer reviewed; Journal article, 2020)Mycobacterium tuberculosis is a global health problem in part as a result of extensive cytotoxicity caused by the infection. Here, we show how M. tuberculosis causes caspase-1/NLRP3/gasdermin D-mediated pyroptosis of human ... -
The short-term impact of methylprednisolone on patient-reported sleep in patients with advanced cancer in a randomized, placebo-controlled, double-blind trial
(Peer reviewed; Journal article, 2020)Purpose: Although corticosteroids are frequently used in patients with advanced cancer, few studies have examined the impact of these drugs on patient-reported sleep. We aimed to examine the short-term impact of ... -
NMR-Based Prostate Cancer Metabolomics
(Journal article; Peer reviewed, 2018)Prostate cancer is the second most common malignancy, and the fifth leading cause of cancer-related death among men, worldwide. A major unsolved clinical challenge in prostate cancer is the ability to accurately distinguish ... -
Left ventricular longitudinal shortening: relation to stroke volume and ejection fraction in ageing, blood pressure, body size and gender in the HUNT3 study
(Peer reviewed; Journal article, 2020)Background: Aims of this cross-sectional study were to assess: the relative contribution of left ventricular (LV) systolic long-axis shortening (mean mitral annular plane systolic excursion, MAPSE) to stroke volume (SV), ... -
Radiological review of prior screening mammograms of screen-detected breast cancer
(Peer reviewed; Journal article, 2020)Objective: To perform a radiological review of mammograms from prior screening and diagnosis of screen-detected breast cancer in BreastScreen Norway, a population-based screening program. Methods: We performed a consensus-based ... -
Effects of external inspections on sepsis detection and treatment: a stepped-wedge study With cluster-level randomisation
(Peer reviewed; Journal article, 2020)Objective To evaluate the effects of external inspections on (1) hospital emergency departments’ clinical processes for detecting and treating sepsis and (2) length of hospital stay and 30-day mortality. Design Incomplete ... -
Left ventricular longitudinal shortening: relation to stroke volume and ejection fraction in ageing, blood pressure, body size and gender in the HUNT3 study
(Peer reviewed; Journal article, 2020)Background: Aims of this cross-sectional study were to assess: the relative contribution of left ventricular (LV) systolic long-axis shortening (mean mitral annular plane systolic excursion, MAPSE) to stroke volume (SV), ... -
Oscillations in biological signal
(Doctoral theses at NTNU;2020:302, Doctoral thesis, 2020)This thesis is a study of electrocardiography, blood pressure and glucose signals in the search for oscillatory physiological processes that are of importance for resilience and the development of disease. An oscillation ... -
A needs assessment of resuscitative endovascular balloon occlusion of the aorta (REBOA) in non-traumatic out-of-hospital cardiac arrest in Norway
(Peer reviewed; Journal article, 2020)Introduction: Out of hospital cardiac arrest (OHCA) carries an 86% mortality rate in Norway. Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a potential adjunct in management of non-traumatic cardiac ... -
Physicians’ Recognition and Management of Kidney Disease: A Randomized Vignette Study Evaluating the Impact of the KDIGO 2012 CKD Classification System
(Peer reviewed; Journal article, 2020)Rationale & Objective The Kidney Disease Outcome Quality Initiative (KDOQI) and Kidney Disease: Improving Global Outcomes (KDIGO) chronic kidney disease (CKD) classification systems published in 2002 and 2012, respectively, ... -
Endothelial dysfunction in small arteries and early signs of atherosclerosis in ApoE knockout rats
(Peer reviewed; Journal article, 2020)Endothelial dysfunction is recognized as a major contributor to atherosclerosis and has been suggested to be evident far before plaque formation. Endothelial dysfunction in small resistance arteries has been suggested to ... -
Patient experience with early discharge after total knee arthroplasty: a focus group study
(Peer reviewed; Journal article, 2018)Background Total knee arthroplasty is experienced as a painful procedure, and pain after surgery seems to be the most limiting factor for early mobilisation. Physical exercise is of utter importance for avoiding complications ... -
Metabolic alterations in tissues and biofluids of patients with prostate cancer
(Peer reviewed; Journal article, 2020)Altered metabolism is one of the key molecular characteristics of prostate cancer (PCa) development, and a number of studies have searched for metabolic biomarkers in patient-derived samples. Reported metabolic changes in ... -
A Quality Control System for Automated Prostate Segmentation on T2-Weighted MRI
(Journal article; Peer reviewed, 2020)Computer-aided detection and diagnosis (CAD) systems have the potential to improve robustness and efficiency compared to traditional radiological reading of magnetic resonance imaging (MRI). Fully automated segmentation ... -
Naloxone for opioid overdose - Pharmacological aspects and dosing in clinical practice
(Doctoral theses at NTNU;2020:236, Doctoral thesis, 2020)Dødsfall fra opioidoverdoser er et stort folkehelseproblem og utdeling av nesespray med motgiften nalokson var foreslått som et tiltak for å redde liv. I 2012 fantes det ingen godkjente nesesprayer på markedet. Istedenfor ... -
Breakthrough cancer pain in 2020
(Peer reviewed; Journal article, 2020)Purpose of review An overview on breakthrough cancer pain (BTCP), including inherent limitations of the terminology, assessment, clinical presentation, and treatment options. Recent findings The estimated prevalence ...
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