• A fast 4D B-spline framework for model-based reconstruction and regularization in vector flow imaging 

  Grønli, Thomas; Wigen, Morten Smedsrud; Segers, Patrick; Løvstakken, Lasse (Journal article; Peer reviewed, 2018)

  A generic framework for model-based regularization and reconstruction is described, with applications in a wide range of noisy measurement scenarios. The framework employs automatic differentiation and stochastic gradient ...

• Interleukin-6 receptor inhibition in non-ST-elevation myocardial infarction - Results from a randomized clinical trial 

  Kleveland, Ola (Doctoral theses at NTNU;2019:50, Doctoral thesis, 2019)

  Norsk sammenfatning: Inhibering av interleukin-6 ved hjerteinfarkt uten ST-segment elevasjon i EKG. Resultater fra en randomisert klinisk studie. Dette arbeidet inneholder resultater fra en klinisk, randomisert, ...

• Interleukin-6 receptor inhibition with tocilizumab induces a selective and substantial increase in plasma IP-10 and MIP-1β in non-ST-elevation myocardial infarction 

  Kleveland, Ola; Ueland, Thor; Kunszt, Gabor; Bratlie, Marte; Yndestad, Arne; Broch, Kaspar; Holte, Espen; Ryan, Liv; Amundsen, Brage H.; Bendz, Bjørn; Aakhus, Svend; Espevik, Terje; Halvorsen, Bente; Mollnes, Tom Eirik; Wiseth, Rune; Gullestad, Lars; Aukrust, Pål; Damås, Jan Kristian (Journal article; Peer reviewed, 2018)

  Aim To evaluate the effect of interleukin-6 inhibition with tocilizumab on the cytokine network in patients with acute non-ST-elevation myocardial infarction (NSTEMI). Methods 117 patients with acute NSTEMI were randomised ...

• Serum lipoprotein(a) is not modified by interleukin-6 receptor antagonism or associated with inflammation in non-ST-elevation myocardial infarction 

  Ueland, Thor; Kleveland, Ola; Michelsen, Annika; Wiseth, Rune; Damås, Jan Kristian; Holven, Kirsten Bjørklund; Aukrust, Pål; Gullestad, Lars; Yndestad, Arne; Halvorsen, Bente (Journal article; Peer reviewed, 2018)

  Background The IL-6 receptor antagonist tocilizumab has been shown to attenuate the proatherogenic lipoprotein a [Lp(a)] in rheumatoid arthritis. We evaluated if a single dose of tocilizumab reduced Lp(a) in patients with ...

• Characteristics of Opioid Overdoses and Intranasal Pharmacology of Naloxone 

  Skulberg, Arne Kristian (Doctoral theses at NTNU;2019:84, Doctoral thesis, 2019)

• Serum cytokine patterns in first half of pregnancy 

  Stokkeland, Live Marie Tobiesen; Giskeødegård, Guro F.; Stridsklev, Solhild; Ryan, Liv; Steinkjer, Bjørg; Tangerås, Line Haugstad; Vanky, Eszter; Iversen, Ann-Charlotte (Journal article; Peer reviewed, 2019)

  Introduction Human pregnancy is a state of elevated maternal systemic inflammation, and pregnancy complications are often associated with a dysfunctional immune response. The network of cytokines reflects this complex ...

• Neuropsychological Dysfunction in Chronic Fatigue Syndrome and the Relation between Objective and Subjective Findings 

  Rasouli, Omid; Gotaas, Merethe Otelie Eide; Stensdotter, Ann-Katrin; Landrø, Nils Inge; Dåstøl, Pål; Skovlund, Eva; Fors, Egil Andreas (Journal article; Peer reviewed, 2019)

  Objective: This study aimed to explore the relationship between self-reported cognitive difficulties, objective neuropsychological test performances, and subjective health complaints in chronic fatigue syndrome (CFS) and ...

• Brain atlas for assessing the impact of tumor location on perioperative quality of life in patients with high-grade glioma: A prospective population-based cohort study 

  Sagberg, Lisa Millgård; Iversen, Daniel Høyer; Fyllingen, Even Hovig; Jakola, Asgeir Store; Reinertsen, Ingerid; Solheim, Ole (Journal article; Peer reviewed, 2019)

  Background Tumor location is important for surgical decision making. Particular attention is paid to regions that contain sensorimotor and language functions, but it is unknown if these are the most important regions from ...

• A new procedure for automatic path planning in bronchoscopy 

  Ciobirca, C; Langø, Thomas; Gruionu, G; Leira, Håkon Olav; Gruionu, Lucian; Pastrama, SD (Journal article; Peer reviewed, 2018)

  Virtual bronchoscopy is often used for planning a real bronchoscopy procedure. Software applications are developed for virtual bronchoscopy, involving usually segmentation of the tracheobronchial tree from the medical image ...

• Defining the cut-off point of clinically significant postoperative fatigue in three common fatigue scales 

  Nøstdal, Torkjell; Bernklev, Tomm; Fredheim, Olav Magnus; Paddison, Johanna S.; Ræder, Johan (Journal article; Peer reviewed, 2018)

  Purpose Postoperative fatigue (POF) is an often underestimated problem after surgery. Studies on POF often report fatigue scores without relating this to the clinical relevance for the patients. The aim of this study was ...

• Arm Cycling Combined with Passive Leg Cycling Enhances VO2peak in Persons with Spinal Cord Injury Above the Sixth Thoracic Vertebra 

  Tørhaug, Tom; Brurok, Berit; Hoff, Jan; Helgerud, Jan; Leivseth, Gunnar (Journal article; Peer reviewed, 2018)

• Associations of asthma and asthma control with atrial fibrillation risk: Results from the Nord-Trøndelag health study (HUNT) 

  Cepelis, Aivaras; Brumpton, Ben Michael; Malmo, Vegard; Laugsand, Lars Erik; Loennechen, Jan Pål; Ellekjær, Hanne; Langhammer, Arnulf; Janszky, Imre; Strand, Linn B (Journal article; Peer reviewed, 2018)

  Importance Asthma, a chronic inflammatory airway disease, and atrial fibrillation (AF) share several common pathophysiological mechanisms. Research on the association between asthma and atrial fibrillation is lacking, ...

• Catastrophizing, Solicitous Responses From Significant Others, and Function in Individuals With Neuropathic Pain, Osteoarthritis, or Spinal Pain in the General Population 

  Glette, Mari; Landmark, Tormod; Jensen, Mark P.; Woodhouse, Astrid; Butler, Stephen; Borchgrevink, Petter Chr.; Stiles, Tore C (Journal article; Peer reviewed, 2018)

  That certain psychological factors are negatively associated with function in patients with chronic pain is well established. However, few studies have evaluated these factors in individuals with chronic pain from the ...

• Comparison of Mitochondrial Respiration in M. triceps brachii and M. vastus lateralis Between Elite Cross-Country Skiers and Physically Active Controls 

  Berg, Jonathan; Undebakke, Vidar; Rasch-Halvorsen, Øystein; Aakerøy, Lars; Sandbakk, Øyvind; Tjønna, Arnt Erik (Journal article; Peer reviewed, 2019)

  Rationale: The main purposes of this study were to compare mitochondrial respiration in M. triceps brachii and M. vastus lateralis between elite cross-country (XC) skiers and physically active controls (CON), and to explore ...

• Acute exercise is not cardioprotective and may induce apoptotic signalling in heart surgery: a randomized controlled trial 

  Smenes, Benedikte; Bækkerud, Fredrik Hjulstad; Slagsvold, Katrine Hordnes; Hassel, Erlend; Wohlwend, Martin; Pinho, Maria; Høydal, Morten; Wisløff, Ulrik; Rognmo, Øivind; Wahba, Alexander (Journal article; Peer reviewed, 2018)

  OBJECTIVES During open-heart surgery, the myocardium experiences ischaemia–reperfusion injury. A single bout of moderate, 30-min exercise induces preconditioning and protects the heart from ischaemia–reperfusion injury ...

• O-GlcNAc Transferase Inhibition Differentially Affects Breast Cancer Subtypes 

  Barkovskaya, Anna; Seip, Kotryna; Hilmarsdòttir, Bylgja; Mælandsmo, Gunhild Mari; Moestue, Siver Andreas; Itkonen, Harri (Journal article; Peer reviewed, 2019)

  Post-translational modification of intracellular proteins with a single N-acetylglucosamine sugar (O-GlcNAcylation) regulates signaling, proliferation, metabolism and protein stability. In breast cancer, expression of the ...

• Detection and differentiation of breast cancer sub-types using a cPLA2a activatable fluorophore 

  Chiorazzo, MG; Tunset, Hanna Maja; Popov, AV; Johansen, Berit; Moestue, Siver Andreas; Delikatny, EJ (Journal article; Peer reviewed, 2019)

  Cytosolic phospholipase A2α (cPLA2α) has been shown to be elevated in breast cancer and is a potential biomarker in the differentiation of molecular sub-types. Using a cPLA2α activatable fluorophore, DDAO arachidonate, we ...

• Adherence to a Long-Term Physical Activity and Exercise Program After Stroke Applied in a Randomized Controlled Trial 

  Gunnes, Mari; Langhammer, Birgitta; Aamot, Inger Lise; Lydersen, Stian; Ihle-Hansen, Hege; Indredavik, Bent; Reneflot, Kristine Helen; Schroeter, Walburga; Askim, Torunn (Journal article; Peer reviewed, 2018)

  Background Persistent physical activity is important to maintain motor function across all stages after stroke. Objective The objective of this study was to investigate adherence to an 18-month physical activity and ...

• Magnetic resonance imaging T1- and T2-mapping to assess renal structure and function: a systematic review and statement paper 

  Wolf, Marcos; de Boer, Anneloes; Sharma, Kanishka; Boor, Peter; Leiner, Tim; Sunder-Plassman, Gere; Moser, Ewald; Caroli, Anna; Jerome, Neil Peter (Journal article; Peer reviewed, 2018)

  This systematic review, initiated by the European Cooperation in Science and Technology Action Magnetic Resonance Imaging Biomarkers for Chronic Kidney Disease (PARENCHIMA), focuses on potential clinical applications of ...

• Pharmacokinetics and -dynamics of intramuscular and intranasal naloxone: an explorative study in healthy volunteers 

  Skulberg, Arne Kristian; Tylleskär, Ida; Nilsen, Turid; Skarra, Sissel; Salvesen, Øyvind; Sand, Trond; Loftsson, Thorsteinn; Dale, Ola (Journal article; Peer reviewed, 2018)

  Purpose This study aimed to develop a model for pharmacodynamic and pharmacokinetic studies of naloxone antagonism under steady-state opioid agonism and to compare a high-concentration/low-volume intranasal naloxone ...

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