• Studying the Origin of Reverberation Clutter in Echocardiography: In Vitro Experiments and In Vivo Demonstrations 

  Fatemi, Ali; Berg, Erik Andreas Rye; Rodriguez-Molares, Alfonso (Peer reviewed; Journal article, 2019)

  Clutter in echocardiography hinders the visualization of the heart and reduces the diagnostic value of the images. The detailed mechanisms that generate clutter are, however, not well understood. We present five different ...

• Analysis of Intra-Tumoral Macrophages and T Cells in Non-Small Cell Lung Cancer (NSCLC) Indicates a Role for Immune Checkpoint and CD200-CD200R Interactions 

  Tøndell, Anders; Subbannayya, Yashwanth; Wahl, Sissel Gyrid Freim; Flatberg, Arnar; Sørhaug, Sveinung; Børset, Magne; Haug, Markus (Peer reviewed; Journal article, 2021)

  Lung cancer is the leading cause of cancer-related death worldwide, accounting for nearly one-fifth of all cancer-related deaths. Immunotherapy with immune checkpoint inhibitors has become one of the most promising approaches ...

• Peak oxygen uptake and cardiovascular risk and disease in a healthy population 

  Letnes, Jon Magne (Doctoral theses at NTNU;2021:113, Doctoral thesis, 2021)

  SAMMENDRAG Kondisjon er vist å være en sterk risikofaktor for hjerte-karsykdom og død. Mesteparten av tidligere forskning på kondisjon som risikofaktor har vært gjennomført ved indirekte og mindre nøyaktige metoder ...

• Continuous subcutaneous infusion for pain control in dying patients: experiences from a tertiary palliative care center 

  Fürst, Per; Lundström, Staffan; Klepstad, Pål; Strang, Peter (Peer reviewed; Journal article, 2020)

  Background Continuous subcutaneous infusion (CSCI) via ambulatory infusion pump (AIP) is a valuable method of pain control in palliative care. When using CSCI, low-dose methadone as add-on to other opioids might be an ...

• Effect of Aerobic Exercise Intensity on Energy Expenditure and Weight Loss in Severe Obesity-A Randomized Controlled Trial 

  Berge, Jarle; Hjelmesæth, Jøran; Hertel, Jens Kristoffer; Gjevestad, Espen Svendsen; Småstuen, Milada Cvancarova; Johnson, Line Kristin; Martins, Catia; Andersen, Eivind; Helgerud, Jan; Støren, Øyvind (Peer reviewed; Journal article, 2021)

  Objective This study aimed to compare the effects of two aerobic exercise programs of different intensities on energy expenditure. Methods This was a single‐center randomized controlled trial of patients with severe obesity ...

• Retrospective Transmit beamforming and Coherent Plane-Wave Compounding for Microvascular Doppler Imaging: A Comparison Study 

  Golfetto, Cristiana; Ekroll, Ingvild Kinn; Torp, Hans; Løvstakken, Lasse; Avdal, Jørgen (Peer reviewed; Journal article, 2020)

  Imaging blood flow in small vessels is of great clinical value for evaluating increased vascularization, potentially related to angiogenesis in cancer or inflammation processes in musculoskeletal disease. Using a traditional ...

• Does a history of cardiovascular disease or cancer affect mortality after SARS-CoV-2 infection? 

  Kvåle, Rune; Bønaa, Kaare Harald; Forster, Rachel Bedenis; Gravningen, Kirsten Midttun; Juliusson, Pétur Benedikt; Myklebust, Tor Åge (Peer reviewed; Journal article, 2021)

  BAKGRUNN Hjerte- og karsykdommer og kreft har vært beskrevet som mulige risikofaktorer for død av covid-19. Hensikten med studien er å undersøke om tidligere påvist hjerte- og karsykdom eller kreft har påvirket risiko for ...

• Effect of side branch flow upon physiological indices in coronary artery disease 

  Gosling, Rebecca C.; Sturdy, Jacob; Morris, Paul D.; Fossan, Fredrik Eikeland; Hellevik, Leif Rune; Lawford, Patricia V.; Hose, David Rodney; Gunn, Julian P. (Peer reviewed; Journal article, 2020)

  Recent efforts have demonstrated the ability of computational models to predict fractional flow reserve from coronary artery imaging without the need for invasive instrumentation. However, these models include only larger ...

• Exploring use of activity monitors for patients with obesity during weight-loss treatment - a qualitative study 

  Følling, Ingrid Sørdal; Oldervoll, Line Merethe; Hilmarsen, Christina Wikstrøm; Ersfjord, Ellen Margrete Iveland (Peer reviewed; Journal article, 2021)

  Background Obesity is a major health concern in western countries. In Norway, patients with obesity can attend weight-loss programmes, which focus on changes in dietary and physical activity habits. Use of self-monitoring ...

• Improper monitoring and deviations from physiologic treatment goals in patients with brain injury in the early phases of emergency care. 

  Andersen, Siri Kojen; Hustveit, Ragnhild; Frøland, Erlend; Uleberg, Oddvar; Kruger, Andreas; Klepstad, Pål; Nordseth, Trond (Peer reviewed; Journal article, 2020)

  Severe traumatic brain injury (TBI), out-of-hospital cardiac arrest (OHCA) and intracerebral- and subarachnoid hemorrhage (ICH/SAH) are conditions associated with high mortality and morbidity. The aim of this study was to ...

• EACVI survey on investigations and imaging modalities in chronic coronary syndromes 

  Bularga, Anda; Saraste, Antti; Fontes-Carvalho, Ricardo; Holte, Espen; Cameli, Matteo; Michalski, Blazej; Williams, Michelle C.; Podlesnikar, Tomaz; D'Andrea, Antonello; Stankovic, Ivan; Mills, Nicholas L.; Manka, Robert; Newby, David E.; Schultz-Menger, Jeanette; Haugaa, Kristina; Dweck, Mark R. (Peer reviewed; Journal article, 2021)

  Aims The European Association of Cardiovascular Imaging (EACVI) Scientific Initiatives Committee performed a global survey to evaluate current practice for the assessment and management of patients with suspected and ...

• Better Automatic Interpretation of Cement Evaluation Logs through Feature Engineering 

  Viggen, Erlend Magnus; Løvstakken, Lasse; Merciu, Ioan Alexandru; Måsøy, Svein-Erik (Chapter, 2021)

  We build systems to automatically interpret cement evaluation logs using supervised machine learning (ML). Such systems can provide instant rough interpretations that may then be used as a basis for human interpretation. ...

• Decidual and placental NOD1 is associated with inflammation in normal and preeclamptic pregnancies 

  Rakner, Johanne Johnsen; Silva, Gabriela; Mundal, Siv Boon; Thaning, Astrid Josefin; Elschot, Mattijs; Ostrop, Jenny; Thomsen, Liv Cecilie Vestrheim; Bjørge, Line; Gierman, Lobke; Iversen, Ann-Charlotte (Peer reviewed; Journal article, 2021)

  Introduction: Inflammation is a normal physiological process that increases to harmful levels in preeclampsia. It affects the interaction between maternal immune cells and fetal trophoblasts at both sites of the maternal-fetal ...

• Rhinosinusitis without Nasal Polyps in COPD 

  Øie, Marte Rystad; Dahlslett, Sarah Bettina; Sue-Chu, Malcolm; Helvik, Anne-Sofie; Steinsvåg, Sverre Karmhus; Thorstensen, Wenche Moe (Peer reviewed; Journal article, 2020)

  The validity of the united airway disease concept for rhinosinusitis (RS) and chronic obstructive pulmonary disease (COPD) has been questioned because of methodological limitations in previous studies. In this study we ...

• Effects of tilt on cerebral hemodynamics measured by NeoDoppler in healthy neonates 

  Jarmund, Anders Hagen; Ødegård, Siv Steinsmo; Torp, Hans; Nyrnes, Siri Ann (Peer reviewed; Journal article, 2021)

  Background: Today, there are conflicting descriptions of how neonates respond to tilt. Examining physiologic responses of cerebral blood flow velocities (BFVs) in challenging situations like a tilt requires equipment that ...

• Right Ventricular Flow Dynamics in Dilated Right Ventricles: Energy Loss Estimation Based on Blood Speckle Tracking Echocardiography-A Pilot Study in Children 

  Mawad, Wadi; Løvstakken, Lasse; Fadnes, Solveig; Grønli, Thomas; Segers, Patrick; Mertens, Luc; Nyrnes, Siri Ann (Peer reviewed; Journal article, 2021)

  Using blood speckle tracking (BST) based on high-frame-rate echocardiography (HFRE), we compared right ventricle (RV) flow dynamics in children with atrial septal defects (ASDs) and repaired tetralogy of Fallot (rTOF). ...

• Survival of glioblastoma in relation to tumor location: a statistical tumor atlas of a population-based cohort 

  Fyllingen, Even Hovig; Bø, Lars Eirik; Reinertsen, Ingerid; Jakola, Asgeir Store; Sagberg, Lisa Millgård; Berntsen, Erik Magnus; Salvesen, Øyvind; Solheim, Ole (Peer reviewed; Journal article, 2021)

  Purpose Previous studies on the effect of tumor location on overall survival in glioblastoma have found conflicting results. Based on statistical maps, we sought to explore the effect of tumor location on overall survival ...

• Phosphatase of Regenerating Liver-3 Regulates Cancer Cell Metabolism in Multiple Myeloma 

  Abdollahi, Pegah; Vandsemb, Esten; Elsaadi, Samah; Røst, Lisa Marie; Yang, Rui; Hjort, Magnus Aassved; Andreassen, Trygve; Misund, Kristine; Slørdahl, Tobias Schmidt; Rø, Torstein Baade; Sponaas, Anne-Marit; Moestue, Siver Andreas; Bruheim, Per; Børset, Magne (Peer reviewed; Journal article, 2021)

  Cancer cells often depend on microenvironment signals from molecules such as cytokines for proliferation and metabolic adaptations. PRL‐3, a cytokine‐induced oncogenic phosphatase, is highly expressed in multiple myeloma ...

• Sonopermeation Enhances Uptake and Therapeutic Effect of Free and Encapsulated Cabazitaxel 

  Snipstad, Sofie; Mørch, Ýrr; Sulheim, Einar; Åslund, Andreas; Pedersen, André; Hansen, Rune; Davies, Catharina de Lange; Berg, Sigrid (Peer reviewed; Journal article, 2021)

  Delivery of drugs and nanomedicines to tumors is often heterogeneous and insufficient and, thus, of limited efficacy. Microbubbles in combination with ultrasound have been found to improve delivery to tumors, enhancing ...

• Influenza vaccination and risk for cardiovascular events: a nationwide self-controlled case series study 

  Sen, Abhijit; Bakken, Inger Johanne Landsjøåsen; Govatsmark, Ragna Elise Støre; Varmdal, Torunn; Bønaa, Kaare Harald; Mukamal, Kenneth Jay; Håberg, Siri Eldevik; Janszky, Imre (Peer reviewed; Journal article, 2021)

  Background US and European guidelines diverge on whether to vaccinate adults who are not at high risk for cardiovascular events against influenza. Here, we investigated the associations between influenza vaccination and ...

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