Institutt for klinisk og molekylær medisin: Nye registreringer
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Direct oral anticoagulant concentrations and adherence in stroke patients
(Journal article; Peer reviewed, 2023)No therapeutic ranges linking drug concentrations of apixaban and rivaroxaban to clinical outcomes have been defined. We investigated whether direct oral anticoagulant (DOAC) concentrations among patients admitted to ... -
Seven classes of antiviral agents
(Journal article; Peer reviewed, 2022)The viral epidemics and pandemics have stimulated the development of known and the discovery of novel antiviral agents. About a hundred mono- and combination antiviral drugs have been already approved, whereas thousands ... -
Visualization Techniques in VR for Vocational Education: Comparison of Realism and Diegesis on Performance, Memory, Perception and Perceived Usability
(Communications in Computer and Information Science (CCIS);, Chapter, 2024)Designing highly realistic and immersive virtual reality (VR) environments has become crucial for enhancing the user experience within human-machine interactions. However, there is limited research regarding the utilization, ... -
Insight into ALKBH8-related intellectual developmental disability based on the first pathogenic missense variant
(Peer reviewed; Journal article, 2021)ALKBH8 is a methyltransferase that modifies tRNAs by methylating the anticodon wobble uridine residue. The syndrome of ALKBH8-related intellectual developmental disability (MRT71) has thus far been reported solely in the ... -
Preterm General Movements in Prediction of Neurodevelopmental Disability and Cerebral Palsy at Two Years: A Prospective Cohort Study.
(Peer reviewed; Journal article, 2022)Background A neurological assessment before discharge from the NICU would enable early targeted intervention to mitigate the risk and severity of cerebral palsy (CP) and neurodevelopmental disability. Objective To ... -
Safe-in-Man Broad Spectrum Antiviral Agents
(Chapter, 2021)Emerging and re-emerging viral diseases occur with regularity within the human population. The conventional ‘one drug, one virus’ paradigm for antivirals does not adequately allow for proper preparedness in the face of ... -
Ultrasound examination of the pelvic floor during active labor: A longitudinal cohort study
(Journal article; Peer reviewed, 2023)Introduction: There is limited evidence about changes in the pelvic floor during active labor. We aimed to investigate changes in hiatal dimensions during the active first stage of labor and associations with fetal descent ... -
Can ultrasound on admission in active labor predict labor duration and a spontaneous delivery?
(Journal article; Peer reviewed, 2021)Can ultrasound on admission in active labor predict labor duration and a spontaneous delivery? -
Novel artificial intelligence approach for automatic differentiation of fetal occiput anterior and non-occiput anterior positions during labor
(Journal article; Peer reviewed, 2022)Objectives: To describe a newly developed machine-learning (ML) algorithm for the automatic recognition of fetal head position using transperineal ultrasound (TPU) during the second stage of labor and to describe its ... -
Prevention of obstetric anal sphincter injuries with perineal support and lateral episiotomy: A historical cohort study
(Journal article; Peer reviewed, 2024)Introduction: There are many risk factors for obstetric anal sphincter injury (OASIS) and the interaction between these risk factors is complex and understudied. The many observational studies that have shown a reduction ... -
Visual outcomes and their association with grey and white matter microstructure in adults born preterm with very low birth weight
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Intrapartum ultrasound in women with prolonged first stage of labor
(Journal article; Peer reviewed, 2021)The first stage of labor is from the start of active labor until the cervix is fully dilatated. To assess labor progress during this stage, a clinical examination has traditionally been done. The cervical dilatation, fetal ... -
There are 4, not 7, cardinal movements in labor
(Journal article; Peer reviewed, 2021)The mechanics of labor describe the forces required for fetal descent, and the movements that the fetus must perform to overcome the resistance met by the maternal bony pelvis and soft tissue. The fetus negotiates the birth ... -
Exploring endoplasmic reticulum stress responses and senescence upon infection with respiratory syncytial virus
(Master thesis, 2024)Respiratorisk syncytialt-virus (RS-virus) er et av de vanligste årsakene til akutt respiratorisk infeksjon hos nyfødte og infeksjonen påvirker cellulære mekanismer i vertscellene. Tidligere studier har vist at RS-virus kan ... -
STUDYING THE EPITHELIAL-SMOOTH MUSCLE CROSSTALK IN INTESTINAL TUMOURS
(Master thesis, 2024)Background. Colorectal cancer (CRC) has been one the most aggressive cancers, with increasing prevalence worldwide. However, the pathophysiological molecular mechanisms behind tumour development are still poorly ... -
5-ASA Affects the PPAR-gamma Protein Expression and Chemokine Release in Intestinal Epithelial Cells
(Master thesis, 2024)Bakgrunn: Inflammatorisk tarm sykdom (IBD) er en kronisk immunologisk sykdom som består av ulcerøs kolitt (UC) og Crohn’s sykdom (CD). De karakteriseres av betennelse i fordøyelsessystemet, oftest i tarmene. Hva som ... -
Impact of HLA DR3DQ2 and DR4DQ8 haplotypes on autoimmunity, diabetic phenotype, and comorbidity in individuals with LADA: An analysis of data from two clinical trials and the HUNT study
(Master thesis, 2024)Bakgrunn og hensikt: De viktigste genene assosiert med risiko for autoimmun diabetes er haplotypene HLA-DR3DQ2 og HLA-DR4DQ8. Deres påvirkning på autoimmunitet, diabetisk fenotype og komorbiditet i Latent Autoimmun Diabetes ... -
Contextual Factors Associated with Abuse of Home-Dwelling Persons with Dementia: A Cross-Sectional Exploratory Study of Informal Caregivers
(Peer reviewed; Journal article, 2023)One in six community-dwelling older adults experience elder abuse yearly, and persons with dementia are especially at risk. Although many risk factors for elder abuse have been identified, there are still knowledge gaps ...