Institutt for klinisk og molekylær medisin: Nye registreringer

Viser treff 1-20 av 3554

    • Effect of a low-carbohydrate diet on pain and quality of life in female patients with lipedema: a randomized controlled trial 

      Lundanes, Julianne; Sandnes, Frida Huhta; Gjeilo, Kari Hanne; Hansson, Karl Patrik; Salater, Sissel; Alho Letra Martins, Catia Patricia; Nymo, Siren (Journal article; Peer reviewed, 2024)
      Objective: The primary objective of this study was to evaluate the effect of a low-carbohydrate diet (LCD) compared with a control diet on pain in female patients with lipedema. The secondary objectives were to compare the ...

    • Incidence of invasive infections with Group B streptococcus in adults in Norway 1996–2019: a nationwide registry-based case–control study 

      Uggen, Elise; Olaisen, Camilla; Lyng, Randi Valsø; Simonsen, Gunnar Skov; Bævre-Jensen, Roar Magne; Gran, Frode Width; Åsvold, Bjørn Olav; Nilsen, Tom Ivar Lund; Damås, Jan Kristian; Afset, Jan Egil (Journal article; Peer reviewed, 2024)
      Purpose Group B streptococcus (GBS) colonizes the gastrointestinal and vaginal mucosa in healthy adults, but has also become an increasing cause of invasive infection. The aims of this study were to describe the incidence ...

    • Verdens plastproblem - går det på helsa løs? 

      Widerøe, Marius; Falkenberg, Liv Eggset; Cyvin, Jakob Bonnevie; Richter, Isabell; Klingsheim, Karl; Rokstad, Anne Mari A.; Wagner, Martin; Asbjørnslett, Bjørn Egil (Research report, 2024)

    • Transdiagnostic Associations between Anger Hostility and Chemokine Interferon-gamma Inducible Protein 10 

      Soløy-Nilsen, Hedda; Nygaard-Odeh, Kristin; Kristiansen, Magnhild Gangsøy; Kvig, Erling Inge; Brekke, Ole Lars; Mollnes, Tom Eirik; Berk, Michael; Reitan, Solveig Klæbo; Øiesvold, Terje (Journal article; Peer reviewed, 2024)
      Objective: Many psychiatric disorders are linked to low grade systemic inflammation as measured by systemic cytokine levels. Exploration of cytokines and immune activity and their role in psychiatric symptoms may inform ...

    • Prevalence and change in alcohol consumption in older adults over time, assessed with self-report and Phosphatidylethanol 16:0/18:1 —The HUNT Study 

      Tevik, Kjerstin Elisabeth; Skråstad, Ragnhild Bergene; Saltyte Benth, Jurate; Selbæk, Geir; Bergh, Sverre; Eldholm, Rannveig Sakshaug; Krokstad, Steinar; Helvik, Anne-Sofie (Journal article; Peer reviewed, 2024)
      Background Changes in alcohol consumption may affect older adults’ health. We examined prevalence and changes in the alcohol consumption of older women and men (≥65 years) in Norway over a 24-year period. Methods Data ...

    • Primary Retroperitoneal Lymph Node Dissection as Treatment for Low-volume Metastatic Seminoma in a Population-based Cohort: The Swedish Norwegian Testicular Cancer Group Experience 

      Thor, Anna; Negaard, Helene Francisca Stigter; Grenabo Bergdahl, Anna; Almås, Bjarte; Larsen, Signe Melsen; Lundgren, Per-Olof; Gerdtsson, Axel; Halvorsen, Dag; Johannsdottir, Berglind; Jansson, Anna K.; Hellström, Martin; Wahlqvist, Rolf; Langberg, Carl W.; Hedlund, Annika; Akre, Olof; Glimelius, Ingrid; Ståhl, Olof; Haugnes, Hege Sagstuen; Cohn-Cedermark, Gabriella; Kjellman, Anders; Tandstad, Torgrim (Journal article; Peer reviewed, 2024)
      Background and objective There is an unmet need to avoid long-term morbidity associated with standard cytotoxic treatment for low-volume metastatic seminoma. Our aim was to assess the oncological efficacy and surgical ...

    • Parenteral Nutrition in Palliative Cancer Care: Detrimental, Futile, or Beneficial? 

      Løhre, Erik Torbjørn; Solheim, Tora S; Jakobsen, Gunnhild; Vagnildhaug, Ola Magne; Karlsen, Terese Louise Schmidberger; Habberstad, Ragnhild Hansdatter; Balstad, Trude Rakel; Thronæs, Morten (Journal article; Peer reviewed, 2024)
      Palliative cancer care patients may live for a long time, but malnutrition worsens the prognosis. Parenteral nutrition (PN) is suitable for replenishing a calorie deficit, but its advantages and tolerance late in the cancer ...

    • Impact of Prosigna test on adjuvant treatment decision in lymph node-negative early breast cancer—a prospective national multicentre study (EMIT-1) 

      Ohnstad, Hege Oma; Blix, Egil Støre; Akslen, Lars Andreas; Gilje, Bjørnar; Raj, Sunil Xavier; Skjerven, Helle; Borgen, Elin; Janssen, Emiel; Mortensen, Elin Synnøve; Brekke, Marianne B.; Falk, Ragnhild Sørum; Schlichting, Ellen; Boge, Beate; Songe-Møller, Silje; Olsson, Pernilla Marie A.; Heie, Anette; Mannsåker, Bård; Vestlid, Magdalena Aas; Kursetgjerde, Torgunn; Gravdehaug, Berit; Suhrke, Pål; Sánchez, E.; Bublevic, J.; Røe, Oluf Dimitri; Geitvik, Gry; Halset, Eline Holli; Rypdal, Maria Christine; Langerød, Anita; Lømo, Jon; Garred, Øystein; Porojnicu, Alina Carmen; Engebraaten, O.; Geisler, Jürgen; Lyngra, Marianne; Hansen, M. H.; Søiland, Håvard; Nakken, T.; Asphaug, Lars; Kristensen, Vessela N.; Sørlie, Therese; Sørlie, T.; Nygård, Jan Franz; Kiserud, Cecilie E.; Reinertsen, Kristin Valborg; Russnes, Hege Elisabeth Giercksky; Naume, Bjørn (Journal article; Peer reviewed, 2024)

    • Biomarker endpoints in cancer cachexia clinical trials: Systematic Review 5 of the cachexia endpoint series 

      Yule, Michael S.; Thompson, Joshua; Leesahatsawat, Khachonphat; Sousa, Mariana S.; Anker, Stefan D.; Arends, Jann; Balstad, Trude Rakel; Brown, Leo R.; Bye, Asta; Dajani, Olav; Fallon, Marie; Hjermstad, Marianne Jensen; Jakobsen, Gunnhild; McDonald, James; McGovern, Josh; Roeland, Eric J.; Sayers, Judith; Skipworth, Richard J.E.; Ottestad, Inger; Philips, Iain; Simpson, Melanie Rae; Solheim, Tora S; Vagnildhaug, Ola Magne; McMillan, Donald; Laird, Barry J; Dolan, Ross D. (Journal article; Peer reviewed, 2024)
      Regulatory agencies require evidence that endpoints correlate with clinical benefit before they can be used to approve drugs. Biomarkers are often considered surrogate endpoints. In cancer cachexia trials, the measurement ...

    • Home-based postnatal care following early hospital discharge: a descriptive study of the Midwife Home care programme 

      Skarsgaard, Benedikte Kjetland; Henriksen, Therese Harvold; Dahlberg, Unn; Løvvik, Tone Shetelig; Aune, Ingvild (Journal article; Peer reviewed, 2024)
      Objective At St. Olav’s University Hospital in Trondheim, Norway, “Midwife Home” (MH) is an integrated home-based postnatal service for mothers who want early discharge (i.e. 6–24 h) after giving birth. The purpose of our ...

    • Body weight and composition endpoints in cancer cachexia clinical trials: Systematic Review 4 of the cachexia endpoints series 

      Brown, Leo R.; Sousa, Mariana S.; Yule, Michael S.; Baracos, Vickie E.; McMillan, Donald C.; Arends, Jann; Balstad, Trude Rakel; Bye, Asta; Dajani, Olav; Dolan, Ross D.; Fallon, Marie T.; Greil, Christine; Hjermstad, Marianne Jensen; Jakobsen, Gunnhild; Maddocks, Matthew; McDonald, James; Ottestad, Inger; Phillips, Iain; Sayers, Judith; Simpson, Melanie Rae; Vagnildhaug, Ola Magne; Solheim, Tora S; Laird, Barry J; Skipworth, Richard J.E. (Journal article; Peer reviewed, 2024)
      Significant variation exists in the outcomes used in cancer cachexia trials, including measures of body composition, which are often selected as primary or secondary endpoints. To date, there has been no review of the most ...

    • General practitioners retiring or relocating and its association with healthcare use and mortality: a cohort study using Norwegian national data 

      Vinjerui, Kristin Hestmann; Asheim, Andreas; Anthun, Kjartan Sarheim; Carlsen, Fredrik; Mjølstad, Bente Prytz; Nilsen, Sara Marie; Pape, Kristine; Bjørngaard, Johan Håkon (Journal article; Peer reviewed, 2024)

    • Quality of life endpoints in cancer cachexia clinical trials: Systematic review 3 of the cachexia endpoints series 

      Hjermstad, Marianne Jensen; Jakobsen, Gunnhild; Arends, Jann; Balstad, Trude Rakel; Brown, Leo R.; Bye, Asta; Coats, Andrew J.S.; Dajani, Olav; Dolan, Ross D.; Fallon, Marie T.; Greil, Christine; Grzyb, Alexandra; Kaasa, Stein; Koteng, Lisa Heide; May, Anne M.; McDonald, James; Ottestad, Inger; Philips, Iain; Roeland, Eric J.; Sayers, Judith; Simpson, Melanie Rae; Skipworth, Richard J.E.; Solheim, Tora S; Sousa, Mariana S.; Vagnildhaug, Ola Magne; Laird, Barry J.A. (Journal article; Peer reviewed, 2024)
      The use of patient-reported outcomes (PROMs) of quality of life (QOL) is common in cachexia trials. Patients' self-report on health, functioning, wellbeing, and perceptions of care, represent important measures of efficacy. ...

    • Serum and salivary inflammatory biomarkers in juvenile idiopathic arthritis—an explorative cross-sectional study 

      Cetrelli, Lena Elisabet; Lundestad, Anette; Gil, Elisabeth Grut; Fischer, Johannes Maria; Halbig, Josefine Mareile; Frid, Paula Hanna Therese; Angenete, Oskar W; Rosén, Annika; Tylleskär, Karin Birgitta; Luukko, Keijo; Nordal, Ellen Berit; Åstrøm, Anne-Kristine N; Skeie, Marit Slåttelid; Stunes, Astrid Kamilla; Bletsa, Athanasia; Sen, Abhijit; Feuerherm, Astrid Jullumstrø; Rygg, Marite (Journal article; Peer reviewed, 2024)
      Background Biomarkers may be useful in monitoring disease activity in juvenile idiopathic arthritis (JIA). With new treatment options and treatment goals in JIA, there is an urgent need for more sensitive and responsive ...

    • Disease activity trajectories from childhood to adulthood in the population-based Nordic juvenile idiopathic arthritis cohort 

      Rypdal, Veronika Gjertsen; Glerup, Mia; Rypdal, Martin Wibe; Arnstad, Ellen Dalen; Aalto, Kristiina; Berntson, Lillemor; Fasth, Anders; Herlin, Troels; Myrup, Charlotte; Peltoniemi, Suvi; Rygg, Marite; Nordal, Ellen Berit (Journal article; Peer reviewed, 2024)
      Objectives To identify long-term disease activity trajectories from childhood to adulthood by using the clinical Juvenile Arthritis Disease Activity Score (cJADAS10) in juvenile idiopathic arthritis (JIA). Second, to ...

    • Body mass index is associated with health-related quality of life and disease characteristics in young adults with juvenile idiopathic arthritis 

      Tuomi, Anna-Kaisa; Rebane, Katariina; Arnstad, Ellen Dalen; Berntson, Lillemor; Fasth, Anders; Glerup, Mia; Herlin, Troels; Kautiainen, Hannu; Nordal, Ellen Berit; Peltoniemi, Suvi; Rygg, Marite; Rypdal, Veronika Gjertsen; Zak, Marek; Aalto, Kristiina (Journal article; Peer reviewed, 2024)
      Background There is a growing interest concerning the relationship between obesity and several medical conditions and inflammation. Nevertheless, there is a lack of studies regarding body mass index (BMI) among patients ...

    • First-line oxaliplatin-based chemotherapy and nivolumab for metastatic microsatellite-stable colorectal cancer—the randomised METIMMOX trial 

      Ree, Anne Hansen; Saltyte Benth, Jurate; Hamre, Hanne Mari; Kersten, Christian; Hofsli, Eva; Guren, Marianne; Sorbye, Halfdan; Johansen, Christin; Negård, Anne; Bjørnetrø, Tonje; Nilsen, Hilde; Berg, Jens Petter; Flatmark, Kjersti; Meltzer, Sebastian (Journal article; Peer reviewed, 2024)
      Background We evaluated first-line treatment of metastatic microsatellite-stable colorectal cancer with short-course oxaliplatin-based chemotherapy alternating with immune checkpoint blockade. Methods Patients were ...

    • Appetite and dietary intake endpoints in cancer cachexia clinical trials: Systematic Review 2 of the cachexia endpoints series 

      Vagnildhaug, Ola Magne; Balstad, Trude Rakel; Ottestad, Inger; Bye, Asta; Greil, Christine; Arends, Jann; Baracos, Vickie; Brown, Leo R.; Dajani, Olav; Dolan, Ross D.; Fallon, Marie; Fraser, Eilidh; Grzyb, Aleksandra; Hjermstad, Marianne Jensen; Jakobsen, Gunnhild; Kaasa, Stein; McDonald, James; Philips, Iain; Sayers, Judith; Simpson, Melanie Rae; Sousa, Mariana S.; Skipworth, Richard J.E.; Laird, Barry J.A.; Solheim, Tora S (Journal article; Peer reviewed, 2024)
      There is no consensus on the optimal endpoint(s) in cancer cachexia trials. Endpoint variation is an obstacle when comparing interventions and their clinical value. The aim of this systematic review was to summarize and ...

    • The association between age and long-term quality of life after curative treatment for prostate cancer: a cross-sectional study 

      Sletten, Reidun; Christiansen, Ola B.; Oldervoll, Line Merethe; Åstrøm, Lennart; Skjellegrind, Håvard Kjesbu; Saltyte Benth, Jurate; Kirkevold, Øyvind; Bergh, Sverre; Grønberg, Bjørn Henning; Rostoft, Siri; Bye, Asta; Mork, Paul Jarle; Slaaen, Marit (Journal article; Peer reviewed, 2024)
      Objective: We aimed to investigate the associations between age at radical prostate cancer treatment and long-term global quality of life (QoL), physical function (PF), and treatment-related side effects. Material and ...

    • Hever kvaliteten på behandling av kreft 

      Helland, Åslaug; Steinskog, Eli Sihn Samdal; Blix, Egil St⊘re; Flobak, Åsmund; Brabrand, Sigmund; Puco, Katarina; Niehusmann, Pitt; Meltzer, Sebastian; Oppedal, Irja Alida; Haug, Åse; Blix, Egil Støre; Torkildsen, Cecilie Fredvik; Randen, Ulla; Gilje, Bj⊘rnar; Gilje, Bjørnar; L⊘nning, Per Eystein; Lønning, Per Eystein; Gjertsen, Bjørn Tore; Hovland, Randi; Russnes, Hege Elisabeth Giercksky; Fagereng, Gro Live; Smeland, Sigbjørn; Tasken, Kjetil (Journal article; Peer reviewed, 2024)