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dc.contributor.authorThomsen, Ruth Stoklund
dc.contributor.authorNilsen, Tom Ivar Lund
dc.contributor.authorHaugeberg, Glenn
dc.contributor.authorSitter, Beathe
dc.contributor.authorKavanaugh, Arthur
dc.contributor.authorPedersen, Susanne Juhl
dc.contributor.authorHoff, Mari
dc.date.accessioned2024-01-16T13:56:28Z
dc.date.available2024-01-16T13:56:28Z
dc.date.created2023-10-03T08:44:57Z
dc.date.issued2023
dc.identifier.issn1471-2474
dc.identifier.urihttps://hdl.handle.net/11250/3111904
dc.description.abstractBackground In psoriatic arthritis (PsA) there is a theoretical risk of increased disease activity related to strenuous physical activity, including exercise. We evaluated the effect of high intensity interval training (HIIT) on objective measures of inflammation in PsA assessed by ultrasound (US) of peripheral joints and entheses, and by bone marrow edema (BME) on MRI of the sacroiliac joints (SIJ) and spine. Methods We randomly assigned 67 PsA patients to an intervention group that performed structured HIIT for 11 weeks, or to a control group instructed not to change their physical exercise habits. Outcome measures included US evaluation of the total cohort and MRI in a subgroup of 41; both assessed at 3 months. We calculated the proportions with an increased US B-mode and power-doppler (PD) signal of joints and entheses and Spondyloarthritis-Research-Consortium-of-Canada (SPARCC)-BME score of the SIJ and spine for both groups. Results Proportions with an increased US B-mode score of the joints were 32% and 28% in HIIT and control groups, respectively. Corresponding proportions of PD scores of the joints were 7% and 10% and PD scores of entheses were 32% and 31%. The proportions with increased MRI BME of the SIJ were 6% in the HIIT group and 10% in the control group. Corresponding proportions were 6% and 5% for the MRI BME of the spine. Conclusion In PsA patients with a low to moderate disease activity, there was no clear evidence of objectively measured increased inflammation after HIIT, as evaluated by US and MRI.en_US
dc.language.isoengen_US
dc.publisherBioMed Central Ltd.en_US
dc.rightsNavngivelse 4.0 Internasjonal*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/deed.no*
dc.titleChanges of inflammation in patients with psoriatic arthritis after high intensity interval training assessed by ultrasound and MRI, a randomized controlled trialen_US
dc.title.alternativeChanges of inflammation in patients with psoriatic arthritis after high intensity interval training assessed by ultrasound and MRI, a randomized controlled trialen_US
dc.typePeer revieweden_US
dc.typeJournal articleen_US
dc.description.versionpublishedVersionen_US
dc.source.volume24en_US
dc.source.journalBMC Musculoskeletal Disordersen_US
dc.identifier.doi10.1186/s12891-023-06871-3
dc.identifier.cristin2181161
dc.source.articlenumber743en_US
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1


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Navngivelse 4.0 Internasjonal
Except where otherwise noted, this item's license is described as Navngivelse 4.0 Internasjonal