• The impact of gender, puberty, and pregnancy in patients with POLG disease 

  Hikmat, Omar; Naess, Karin; Engvall, Martin; Klingenberg, Claus; Rasmussen, Magnhild; Tallaksen, Chantal; Samsonsen, Christian; Brodtkorb, Eylert; Ostergaard, Elsebet; de Coo, Rene; Pias-Peleteiro, Leticia; Isohanni, Pirjo; Uusimaa, Johanna; Darin, Niklas; Rahman, Shamima; Bindoff, Laurence (Peer reviewed; Journal article, 2020)

  Objective To study the impact of gender, puberty, and pregnancy on the expression of POLG disease, one of the most common mitochondrial diseases known. Methods Clinical, laboratory, and genetic data were collected ...

• Anbefalinger om bruk av rotavirusvaksine i Norge 

  Døllner, Henrik; Flem, elmira; Realfsen, Astrid; Rojahn, Astrid; Steenberg, Dianne; Sandbu, Synne; Vainio, Kirsti; Willbergh, Kine (rapport Nasjonalt folkehelseinstitutt;, Research report, 2013)

  Rotavirus smitter vanligvis ved nærkontakt og gir magesyke (gastroenteritt) som rammer praktisk talt alle barn i verden før de fyller fem år. Globalt er dette en viktig dødsårsak for spedbarn. I Norge er rotavirussykdom ...

• Effects of digital cognitive behavioural therapy for insomnia on insomnia severity: a large-scale randomised controlled trial 

  Vedaa, Øystein; Kallestad, Håvard; Scott, Janine Linda; Smith, Otto Robert Frans; Pallesen, Ståle; Morken, Gunnar; Langsrud, Knut; Gehrman, Philip; Thorndike, Frances P.; Ritterband, Lee M.; Harvey, Allison G.; Stiles, Tore C; Sivertsen, Børge (Peer reviewed; Journal article, 2020)

  Background Although several large-scale randomised controlled trials have shown the efficacy of digital cognitive behavioural therapy for insomnia (dCBT-I), there is a need to validate widespread dissemination of dCBT-I ...

• Tumor budding score predicts lymph node status in oral tongue squamous cell carcinoma and should be included in the pathology report 

  Bjerkli, Inger-Heidi; Laurvik, Helene; Nginamau, Elisabeth Sivy; Søland, Tine Merete; Costea, Daniela Elena; Hov, Håkon; Uhlin-Hansen, Lars; Hadler-Olsen, Elin Synnøve; Steigen, Sonja Eriksson (Journal article; Peer reviewed, 2020)

  Background The majority of oral cavity cancers arise in the oral tongue. The aim of this study was to evaluate the prognostic value of tumor budding in oral tongue squamous cell carcinoma, both as a separate variable and ...

• Left ventricular longitudinal shortening: relation to stroke volume and ejection fraction in ageing, blood pressure, body size and gender in the HUNT3 study 

  Støylen, Asbjørn; Dalen, Håvard; Hansen, Harald Edvard Mølmen (Peer reviewed; Journal article, 2020)

  Background: Aims of this cross-sectional study were to assess: the relative contribution of left ventricular (LV) systolic long-axis shortening (mean mitral annular plane systolic excursion, MAPSE) to stroke volume (SV), ...

• A needs assessment of resuscitative endovascular balloon occlusion of the aorta (REBOA) in non-traumatic out-of-hospital cardiac arrest in Norway 

  Brede, Jostein Rødseth; Kramer-Johansen, Jo; Rehn, Marius (Peer reviewed; Journal article, 2020)

  Introduction: Out of hospital cardiac arrest (OHCA) carries an 86% mortality rate in Norway. Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a potential adjunct in management of non-traumatic cardiac ...

• Physicians’ Recognition and Management of Kidney Disease: A Randomized Vignette Study Evaluating the Impact of the KDIGO 2012 CKD Classification System 

  Hallan, Stein; Rifkin, Dena E; potok, olivia; Langlo, Knut Asbjørn Rise; Dekker, Friedo W.; Ix, Joachim H. (Peer reviewed; Journal article, 2020)

  Rationale & Objective The Kidney Disease Outcome Quality Initiative (KDOQI) and Kidney Disease: Improving Global Outcomes (KDIGO) chronic kidney disease (CKD) classification systems published in 2002 and 2012, respectively, ...

• Spatial distribution of malignant transformation in patients with low-grade glioma 

  Jakola, Asgeir S; Bouget, David Nicolas Jean-Marie; Reinertsen, Ingerid; Skjulsvik, Anne Jarstein; Sagberg, Lisa Millgård; Bø, Hans Kristian; Gulati, Sasha; Sjåvik, Kristin; Solheim, Ole (Journal article; Peer reviewed, 2020)

  Background Malignant transformation represents the natural evolution of diffuse low-grade gliomas (LGG). This is a catastrophic event, causing neurocognitive symptoms, intensified treatment and premature death. However, ...

• Mitochondrial genome-wide association study of migraine – the HUNT Study 

  Børte, Sigrid; Zwart, John-Anker; Skogholt, Anne Heidi; Gabrielsen, Maiken Elvestad; Thomas, Laurent; Fritsche, Lars G; Surakke, Ida; Nielsen, Jonas B.; Zhou, Wei; Wolford, Brooke; Vigeland, Magnus Dehli; Hagen, Knut; Kristoffersen, Espen Saxhaug; Nyholt, Dale R; Chasman, Daniel I; Brumpton, Ben Michael; Willer, Christen; Winsvold, Bendik K S (Peer reviewed; Journal article, 2020)

  Background Variation in mitochondrial DNA (mtDNA) has been indicated in migraine pathogenesis, but genetic studies to date have focused on candidate variants, with sparse findings. We aimed to perform the first mitochondrial ...

• Comparison of peak oxygen uptake between upper-body exercise modes: A systematic literature review and meta-analysis 

  Baumgart, Julia Kathrin; Brurok, Berit; Sandbakk, Øyvind (Peer reviewed; Journal article, 2020)

  Purpose: To compare peak oxygen uptake (VO2peak) between the asynchronous arm crank ergometry (ACE), and synchronous wheelchair ergometry (WERG), wheelchair treadmill (WTR), and upper-body poling (UBP) mode. Methods: ...

• Individual Variation in Adaptive Immune Responses and Risk of Hip Fracture-A NOREPOS Population-Based Cohort Study 

  Dahl, Jesper; Holvik, Kristin; Heldal, Einar; Grimnes, Guri; Hoff, Mari; Finnes, Trine; Apalset, Ellen Margrete; Meyer, Haakon E (Journal article; Peer reviewed, 2020)

  Immune‐mediated bone loss significantly impacts fracture risk in patients with autoimmune disease, but to what extent individual variations in immune responses affect fracture risk on a population level is unknown. To ...

• Metabolic alterations in tissues and biofluids of patients with prostate cancer 

  Andersen, Maria Karoline; Giskeødegård, Guro F.; Tessem, May-Britt (Peer reviewed; Journal article, 2020)

  Altered metabolism is one of the key molecular characteristics of prostate cancer (PCa) development, and a number of studies have searched for metabolic biomarkers in patient-derived samples. Reported metabolic changes in ...

• DNA glycosylase Neil2 contributes to genomic responses in the spleen during clinical prion disease 

  Scheffler, Katja; Jalland, Clara Maria Osnes; Benestad, Sylvie L.; Moldal, Torfinn; Ersdal, Cecilie; Gunnes, Gjermund; Suganthan, Rajikala; Bjørås, Magnar; Tranulis, Michael A. (Peer reviewed; Journal article, 2020)

  The DNA glycosylase Neil2 is a member of the base excision repair (BER) family of enzymes, which are important for repair of oxidative DNA damage. Specifically, Neil2 participates in repair of oxidized bases in single-stranded ...

• Does caesarean delivery in the first pregnancy increase the risk for adverse outcome in the second? A registry-based cohort study on first and second singleton births in Norway 

  Bjellmo, Solveig; Andersen, Guro Lillemoen; Hjelle, Sissel; Klungsøyr, Kari; Krebs, Lone; Lydersen, Stian; Romundstad, Pål Richard; Vik, Torstein (Peer reviewed; Journal article, 2020)

  Objective To explore if newborns in the second pregnancy following a previous caesarean delivery (CD) have higher risk of perinatal mortality or cerebral palsy than newborns in pregnancies following a previous vaginal ...

• Patient experience with early discharge after total knee arthroplasty: a focus group study 

  Høvik, Lise Husby; Aglen, Bjørg; Schnell Husby, Vigdis (Peer reviewed; Journal article, 2018)

  Background Total knee arthroplasty is experienced as a painful procedure, and pain after surgery seems to be the most limiting factor for early mobilisation. Physical exercise is of utter importance for avoiding complications ...

• Health-related quality of life after traumatic brain injury: deriving value sets for the QOLIBRI-OS for Italy, The Netherlands and The United Kingdom 

  Voormolen, Daphne; Polinder, Suzanne; von Steinbuechel, Nicole; Feng, Yan; Wilson, Lindsay; Oppe, Mark; Haagsma, Juanita; Andelic, Nada; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Skandsen, Toril; Røe, Cecilie; Røise, Olav; Vik, Anne; Åkerlund, Cecilia; Adams, Hadie; Amrein, Krisztina; Antoni, Anna; Audibert, Gerard; Azouvi, Philippe; Azzolini, Maria Luisa; Bartels, Ronald; Barzo, Pal; Beauvais, Romuald; Beer, Ronny; Bellander, Bo-Michael; Belli, Antonio; Benali, Habib; Berardino, Maurizio; Beretta, Luigi; Blaabjerg, Morten; Bragge, Peter; Brazinova, Alexandra; Brinck, Vibeke; Brooker, Joanne; Brorsson, Camilla; Buki, Andras; Bullinger, Monika; Cabeleira, Manuel; Caccioppola, Alessio; Calappi, Emiliana; Calvi, Maria Rosa; Cameron, Peter;  Lozano, Guillermo Carbayo; Carbonara, Marco; Castaño-León, Ana M.; Chevallard, Giorgio; Chieregato, Arturo; Citerio, Giuseppe (Journal article; Peer reviewed, 2020)

  Purpose The Quality of Life after Brain Injury overall scale (QOLIBRI-OS) measures health-related quality of life (HRQoL) after traumatic brain injury (TBI). The aim of this study was to derive value sets for the QOLIBRI-OS ...

• A Quality Control System for Automated Prostate Segmentation on T2-Weighted MRI 

  Sunoqrot, Mohammed R. S.; Selnæs, Kirsten Margrete; Sandsmark, Elise; Nketiah, Gabriel Addio; Zavala-Romero, Olmo; Stoyanova, Radka; Bathen, Tone Frost; Elschot, Mattijs (Journal article; Peer reviewed, 2020)

  Computer-aided detection and diagnosis (CAD) systems have the potential to improve robustness and efficiency compared to traditional radiological reading of magnetic resonance imaging (MRI). Fully automated segmentation ...

• Gir ACE-hemmere og angiotensinreseptorantagonister økt risiko for alvorlig covid-19? 

  Aamodt, Anne Hege; Bjørk, Marte-Helene; Tronvik, Erling Andreas; Buanes, Eirik Alnes; Stovner, Lars Jacob; Atar, Dan (Peer reviewed; Journal article, 2020)

  Hypertensjon og diabetes mellitus er risikofaktorer for alvorlig covid-19. Det er blitt reist spørsmål om hvorvidt denne assosiasjonen er relatert til bruk av ACE-hemmere og angiotensin II-reseptorblokkere.

• Relative difference in muscle strength between patients with knee osteoarthritis and healthy controls when tested bilaterally and joint-inclusive: an exploratory cross-sectional study. 

  Vårbakken, Kjartan; Lorås, Håvard; Nilsson, Kjell Gunnar; Engdal, Monika; Stensdotter, Ann-Katrin (Peer reviewed; Journal article, 2019)

  Background: To improve the goal-directedness of strength exercises for patients with knee osteoarthritis (KOA), physical rehabilitation specialists need to know which muscle-groups are most substantially weakened across ...

• MGMT Promoter Methylation Status Is Not Related to Histological or Radiological Features in IDH Wild-type Glioblastomas 

  Mikkelsen, Vilde Elisabeth; Hong, Yan Dai; Stensjøen, Anne Line; Berntsen, Erik Magnus; Salvesen, Øyvind; Solheim, Ole; Torp, Sverre Helge (Peer reviewed; Journal article, 2020)

  O6-methylguanine DNA methyltransferase (MGMT) promoter methylation is an important favorable predictive marker in patients with glioblastoma (GBM). We hypothesized that MGMT status could be a surrogate marker of pretreatment ...

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