St. Olavs hospital
Recent Submissions
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Visuopathy of prematurity: is retinopathy just the tip of the iceberg?
(Peer reviewed; Journal article, 2021)Background: Chronic brain pathology and pre-stroke cognitive impairment (PCI) is predictive of post-stroke dementia. The aim of the current study was to measure pre-stroke neurodegenerative and vascular disease burden found ... -
Informed consent procedures in patients with an acute inability to provide informed consent: Policy and practice in the CENTER-TBI study
(Peer reviewed; Journal article, 2020)Purpose: Enrolling traumatic brain injury (TBI) patients with an inability to provide informed consent in research is challenging. Alternatives to patient consent are not sufficiently embedded in European and national ... -
Surgical Complications in Postchemotherapy Retroperitoneal Lymph Node Dissection for Nonseminoma Germ Cell Tumour: A Population-based Study from the Swedish Norwegian Testicular Cancer Group
(Journal article, 2020)Background Reports on perioperative complications after postchemotherapy retroperitoneal lymph node dissection (PC-RPLND) for nonseminoma germ cell tumour (NSGCT) are from experienced single centres, with a lack of ... -
Randomized phase III trial comparing switch-maintenance pemetrexed with observation followed by pemetrexed at progression in advanced NSCLC
(Peer reviewed; Journal article, 2020)Objectives: Two phase III trials show that maintenance pemetrexed therapy after platinum-doublet chemotherapy prolongs overall survival (OS) and progression free survival (PFS) in advanced non-squamous non-small-cell lung ... -
Functional profiling reveals altered metabolic activity in divers’ oral microbiota during commercial heliox saturation diving
(Peer reviewed; Journal article, 2021)Background: The extreme environment in saturation diving affects all life forms, including the bacteria that reside on human skin and mucosa. The oral cavity alone is home to hundreds of different bacteria. In this study, ... -
Past, present and future of zebrafish in epilepsy research
(Journal article; Peer reviewed, 2021)Animal models contribute greatly to our understanding of brain development and function as well as its dysfunction in neurological diseases. Epilepsy research is a very good example of how animal models can provide us with ... -
Survival and disease recurrence in patients with duodenal neuroendocrine tumours—a single centre cohort
(Journal article; Peer reviewed, 2021)Background: Duodenal neuroendocrine tumours (D-NETs) are rare but increasingly diagnosed. This study aimed to assess the overall survival and recurrence rate among patients treated for D-NETs. Methods: Patients with D-NETs ... -
Loss of statin treatment years during pregnancy and breastfeeding periods in women with familial hypercholesterolemia
(Peer reviewed; Journal article, 2021)Background and aims Women with heterozygous familial hypercholesterolemia (FH) are recommended to initiate statin treatment at the same age as men (from 8 to 10 years of age). However, statins are contraindicated when ... -
Olfactory hallucinations in a population-based sample
(Peer reviewed; Journal article, 2021)Olfactory hallucinations referring to olfactory perceptions in the absence of chemical stimuli, occur in non-clinical and clinical populations. Few studies have investigated their prevalence in the general population and ... -
Examining the educational impact of the mini-CEX: a randomised controlled study
(Journal article; Peer reviewed, 2021)Background: The purpose of this study is to evaluate the mini-Clinical Evaluation Exercise (mini-CEX) as a formative assessment tool among undergraduate medical students, in terms of student perceptions, effects on direct ... -
Lung function and peak oxygen uptake in chronic obstructive pulmonary disease phenotypes with and without emphysema
(Journal article; Peer reviewed, 2021)Previous studies of associations of forced expiratory lung volume in one second (FEV1) with peak oxygen uptake (VO2peak) in chronic obstructive pulmonary disease (COPD) have not taken sex, age and height related variance ... -
Cardiovascular outcomes at recommended blood pressure targets in middle-aged and elderly patients with type 2 diabetes mellitus compared to all middle-aged and elderly hypertensive study patients with high cardiovascular risk
(Peer reviewed; Journal article, 2021)Purpose Event-based clinical outcome trials have shown limited evidence to support guidelines recommendations to lower blood pressure (BP) to <130/80 mmHg in middle-aged and elderly hypertensive patients with diabetes ... -
Non-coding RNAs in human breast milk: A systematic review
(Peer reviewed; Journal article, 2021)Breast milk is the primary source of nutrition and hydration for the newborn infant but also plays an important role in the child’s first immune defense. Additionally, several breast milk factors have been implicated in ... -
Semiquantitative Real-Time PCR to Distinguish Pneumocystis Pneumonia from Colonization in a Heterogeneous Population of HIV-Negative Immunocompromised Patients
(Peer reviewed; Journal article, 2021)Pneumocystis jirovecii is a threat to iatrogenically immunosuppressed individuals, a heterogeneous population at rapid growth. We assessed the ability of an in-house semiquantitative real-time PCR assay to discriminate ... -
Management of cluster headache and other trigeminal autonomic cephalalgias in pregnancy and breastfeeding
(Peer reviewed; Journal article, 2021)Many clinicians lack experience in managing trigeminal autonomic cephalalgias (TACs) in pregnancy and lactation. In addition to cluster headache, TACs include hemicrania continua, paroxysmal hemicrania, and short-lasting ... -
The value of restaging CT following neoadjuvant chemotherapy for resectable gastric cancer. A population-based study
(Journal article; Peer reviewed, 2021)Background Response evaluation following neoadjuvant chemotherapy (NAC) in gastric cancer is debated. The aim of this study was to investigate the value of UICC-downstaging as mode of response evaluation following a ... -
Prevalence and course of anxiety disorders and symptoms from preschool to adolescence: a 6-wave community study
(Journal article; Peer reviewed, 2021)Background: The rate of various anxiety disorders in early childhood and whether they continue into middle childhood or adolescence is not known. We therefore report on the prevalence and stability of DSM-5-defined anxiety ... -
Colorectal cancer patients’ experiences with supervised exercise during adjuvant chemotherapy—A qualitative study
(Peer reviewed; Journal article, 2021)Background Colorectal cancer (CRC) is a common cancer worldwide, with increasing numbers surviving and living with long-term side effects from treatment. Physical exercise during or after treatment may have several beneficial ... -
How the Norwegian population was affected by non-pharmaceutical interventions during the first six weeks of the COVID-19 lockdown
(Journal article; Peer reviewed, 2021)Aims The aim of this study was to examine how the Norwegian general adult population was affected by non-pharmaceutical interventions during the first six weeks of the COVID-19 lockdown. We assessed quarantine, symptoms, ... -
High neuroticism is associated with reduced negative affect following sleep deprivation
(Peer reviewed; Journal article, 2021)The aim was to investigate how neuroticism moderates the affective consequences of personalized mild-moderate partial sleep deprivation. A total of 52 healthy subjects aged 18–35 years completed the NEO PI-3 at baseline, ...
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