Recent Submissions

  • Elevated High Sensitivity C Reactive Protein and Risk of Abdominal Aortic Aneurysm: A Prospective Population Based Study in The Norwegian HUNT Study 

    Håland, Aslak Bryne; Mattsson, Erney; Videm, Vibeke; Albrektsen, Grethe; Nyrønning, Linn Åldstedt (Journal article; Peer reviewed, 2025)
    Objective: Inflammation seems to be crucial in the pathogenesis of abdominal aortic aneurysm (AAA). Previous research links inflammatory biomarkers, such as high sensitivity C reactive protein (hs-CRP), to AAA. Few studies, ...
  • Type 1 Autoimmune Pancreatitis in Europe: Clinical Profile and Response to Treatment 

    Overbeek, Kasper A.; Poulsen, Jakob L.; Lanzillotta, Marco; Holmquist, Olof Dan Sebastian; Macinga, Peter; Demirci, A. Fatih; Sindhunata, Daniko P.; Backhus, Johanna; Algül, Hana; Buijs, Jorie; Levy, Philippe; Kiriukova, Mariia; Goni, Elisabetta; Hollenbach, Marcus; Miksch, Rainer C.; Kunovsky, Lumir; Vujasinovic, Miroslav; Nikolic, Sara; Dickerson, Luke; Hirth, Michael; Neurath, Markus F.; Zumblick, Malte; Vila, Josephine; Jalal, Mustafa; Beyer, Georg; Frost, Fabian; Carrara, Silvia; Kala, Zdenek; Jabandziev, Petr; Sisman, Gurhan; Akyuz, Filiz; Capurso, Gabriele; Falconi, Massimo; Arlt, Alexander; Vleggaar, Frank P.; Barresi, Luca; Greenhalf, Bill; Czakó, László; Hegyi, Peter; Hopper, Andrew; Nayar, Manu K.; Gress, Thomas M.; Vitali, Francesco; Schneider, Alexander; Halloran, Chris M.; Trna, Jan; Okhlobystin, Alexey V.; Dagna, Lorenzo; Cahen, Djuna L.; Bordin, Dmitry; Rebours, Vinciane; Mayerle, Julia; Kahraman, Alisan; Rasch, Sebastian; Culver, Emma; Kleger, Alexander; Martínez-Moneo, Emma; Røkke, Ola; Hucl, Tomas; Olesen, Søren S.; Bruno, Marco J.; Della-Torre, Emanuel; Beuers, Ulrich; Löhr, J.-Matthias; Rosendahl, Jonas (Peer reviewed; Journal article, 2024)
    BACKGROUND & AIMS: Autoimmune pancreatitis (AIP) is an immune-mediated disease of the pancreas with distinct pathophysiology and manifestations. Our aims were to characterize type 1 AIP in a large pan-European cohort and ...
  • “Gastrointestinal Quality of Life After Congenital Duodenal Obstruction Repair: A Nationwide Long-term Follow-up Study” 

    Treider, Martin; Røkkum, Henrik; Sæter, Thorstein; Bjørnland, Kristin (Peer reviewed; Journal article, 2024)
    Background Congenital duodenal obstruction (CDO) is one of the most common gastrointestinal congenital anomalies. Still, patient-reported long-term results are limited. The aims of this study were to evaluate the long-term ...
  • Enteroaggregative Escherichia coli in mid-Norway: A prospective, case control study 

    Haugan, Ingvild; Husby, Marit Gudrun; Skjøtskift, Bjørg; Mostue, Dorothea Aamnes; Brun, Andreas; Olsen, Lene Christin; Simpson, Melanie Rae; Lange, Heidi; Afset, Jan Egil (Peer reviewed; Journal article, 2024)
    Background The use of molecular methods has led to increased detection of Enteroaggregative Escherichia coli (EAEC) in faecal samples. Studies have yielded conflicting results regarding the clinical relevance of this ...
  • Pelvic floor status in opera singers. a pilot study using transperineal ultrasound 

    Volløyhaug, Ingrid; Semmingsen, Tuva Haugen; Laukkanen, Anne-Maria; Karoliussen, Clara; Bjørkøy, Kåre (Peer reviewed; Journal article, 2024)
    Background: Control of pelvic floor muscles (PFM) is emphasized as important to obtain functional breath support in opera singing, but there is not much research that proves PFM function as part of breath support in classical ...
  • Development of a predictive model for patients with bone metastases referred to palliative radiotherapy: Secondary analysis of a multicenter study (the PRAIS trial) 

    Rossi, Romina; Medici, Federica; Habberstad, Ragnhild Hansdatter; Klepstad, Pål; Cilla, Savino; Dall'Agata, Monia; Kaasa, Stein; Caraceni, Augusto Tomasso Giovanni; Morganti, Alessio Giuseppe; Maltoni, Marco (Journal article; Peer reviewed, 2024)
    Background: The decision to administer palliative radiotherapy (RT) to patients with bone metastases (BMs), as well as the selection of treatment protocols (dose, fractionation), requires an accurate assessment of survival ...
  • Progression-free survival versus post-progression survival and overall survival in WHO grade 2 gliomas 

    Sagberg, Lisa Millgård; Salvesen, Øyvind Olav; Jakola, Asgeir Store; Thurin, Erik; De Dios, Eddie; Nawabi, Noah L.A; Kilgallon, John L.; Bernstock, Joshua D.; Kavouridis, Vasileios; Smith, Timothy R.; Solheim, Ole Skeidsvoll (Journal article; Peer reviewed, 2024)
    Background and purpose: Progression-free survival (PFS) remains to be validated as an outcome measure for diffuse WHO grade 2 gliomas, and knowledge about the relationships between PFS, post-progression survival (PPS), and ...
  • Single cell and spatial transcriptomics highlight the interaction of club-like cells with immunosuppressive myeloid cells in prostate cancer 

    Kiviaho, Antti; Eerola, Sini K.; Kallio, Heini M.L.; Andersen, Maria K.; Hoikka, Miina; Salonen, Iida; Spotbeen, Xander; Giesen, Alexander; Parker, Charles T.A.; Taavitsainen, Sinja; Hantula, Olli; Marttinen, Mikael; Harmelo, Ismael; Ismail, Mazlina; Midtbust, Elise; Wess, Maximilian; Devlies, Wout; Sharma, Abhibhav; Krossa, Sebastian; Häkkinen, Tomi; Afyounian, Ebrahim; Vandereyken, Katy; Kint, Sam; Kesseli, Juha; Tolonen, Teemu; Tammela, Teuvo L.J.; Viset, Trond; Størkersen, Øystein; Giskeødegård, Guro F.; Rye, Morten Beck; Murtola, Teemu; Erickson, Andrew; Latonen, Leena; Bova, Steven G.; Mills, Ian Geoffrey; Joniau, Steven; Swinnen, Johannes V.; Voet, Thierry; Mirtti, Tuomas; Attard, Gerhardt; Claessens, Frank; Visakorpi, Tapio; Rautajoki, Kirsi J.; Tessem, May-Britt; Urbanucci, Alfonso; Nykter, Matti; Tiihonen, Aliisa M. (Journal article; Peer reviewed, 2024)
    Prostate cancer treatment resistance is a significant challenge facing the field. Genomic and transcriptomic profiling have partially elucidated the mechanisms through which cancer cells escape treatment, but their relation ...
  • Single-cell multiomics analysis of chronic myeloid leukemia links cellular heterogeneity to therapy response 

    Warfvinge, Rebecca; Geironson Ulfsson, Linda; Dhapola, Parashar; Safi, Fatemeh; Sommarin, Mikael; Soneji, Shamit; Hjorth-Hansen, Henrik; Mustjoki, Satu; Richter, Johan; Thakur, Ram Krishna; Karlsson, Göran (Journal article; Peer reviewed, 2024)
    The advent of tyrosine kinase inhibitors (TKIs) as treatment of chronic myeloid leukemia (CML) is a paradigm in molecularly targeted cancer therapy. Nonetheless, TKI-insensitive leukemia stem cells (LSCs) persist in most ...
  • Systematic review and meta-analysis of birth outcomes in women with polycystic ovary syndrome 

    Bahri Khomami, Mahnaz; Hashemi, Somayeh; Shorakae, Soulmaz; Harrison, Cheryce L.; Piltonen, Terhi T.; Romualdi, Daniela; Tay, Chau Thien; Mousa, Aya; Vanky, Eszter Ilona; Teede, Helena J. (Journal article; Peer reviewed, 2024)
    It is unclear whether polycystic ovary syndrome (PCOS) is an independent risk factor for adverse birth outcomes in the offspring of affected women. Here, we investigate the association of PCOS with birth outcomes in the ...
  • X-bundet hypofosfatemi 

    Wang, Qidi; Akdeniz, Cennet; Heck, Ansgar; Bjørk, Mai Britt; Theisen, Ole Rasmus; Eggesbø, Heidi Beate; Krüger, Tormod Bjartveit; Reseland, Janne Elin; Pihlstrøm, Hege Kampen; Åsvold, Bjørn Olav; Grimnes, Guri; Grytaas, Marianne Aardal; Rafaelsen, Silje Hjorth; Thorsby, Per Medbøe; Wekre, Lena Lande; Finnes, Trine Elisabeth (Journal article; Peer reviewed, 2025)
    X-bundet hypofosfatemi er en sjelden genetisk sykdom som medfører fosfattap i nyrene, redusert mineralisering av tenner og skjelett, deformerte knokler og begrenset mobilitet. Dette har betydelige konsekvenser for helse ...
  • Effect of tocilizumab on endothelial and platelet-derived CXC-chemokines and their association with inflammation and myocardial injury in STEMI patients undergoing primary PCI 

    Woxholt, Sindre; Ueland, Thor; Aukrust, Pål; Anstensrud, Anne Kristine; Broch, Kaspar; Tøllefsen, Ingvild Maria; Seljeflot, Ingebjørg; Halvorsen, Bente; Dahl, Tuva Børresdatter; Huse, Camilla; Andersen, Geir Øystein; Gullestad, Lars; Wiseth, Rune; Damås, Jan Kristian; Kleveland, Ola (Journal article; Peer reviewed, 2025)
    Background: Tocilizumab improves myocardial salvage in ST-elevation myocardial infarction (STEMI) patients when administered before percutaneous coronary intervention (PCI). The mechanisms underlying ischemia-reperfusion ...
  • Deep learning-based postoperative glioblastoma segmentation and extent of resection evaluation: Development, external validation, and model comparison 

    Cepeda, Santiago; Romero, Roberto; Luque, Lidia; García-Pérez, Daniel; Blasco, Guillermo; Luppino, Luigi Tommaso; Kuttner, Samuel; Esteban-Sinovas, Olga; Arrese, Ignacio; Solheim, Ole Skeidsvoll; Eikenes, Live; Karlberg, Anna Maria; Pérez-Núñez, Ángel; Zanier, Olivier; Serra, Carlo; Staartjes, Victor E.; Bianconi, Andrea; Rossi, Luca Francesco; Garbossa, Diego; Escudero, Trinidad; Hornero, Roberto; Sarabia, Rosario (Journal article; Peer reviewed, 2024)
    Background: The pursuit of automated methods to assess the extent of resection (EOR) in glioblastomas is challenging, requiring precise measurement of residual tumor volume. Many algorithms focus on preoperative scans, ...
  • Contraction of Respiratory Viral Infection During air Travel: An Under-Recognized Health Risk for Athletes 

    Ruuskanen, Olli; Døllner, Henrik; Luoto, Raakel; Valtonen, Maarit; Heinonen, Olli J.; Waris, Matti (Journal article; Peer reviewed, 2024)
    Air travel has an important role in the spread of viral acute respiratory infections (ARIs). Aircraft offer an ideal setting for the transmission of ARI because of a closed environment, crowded conditions, and close-contact ...
  • Repeat Prostate-specific Antigen Testing Improves Risk-based Selection of Men for Prostate Biopsy After Magnetic Resonance Imaging 

    Davik, Petter; Elschot, Mattijs; Bathen, Tone Frost; Bertilsson, Helena Maria (Journal article; Peer reviewed, 2024)
    Background and objective: The aim of our study was to investigate whether repeat prostate-specific antigen (PSA) testing as currently recommended improves risk stratification for men undergoing magnetic resonance imaging ...
  • Application of Photodynamic Therapy with 5-Aminolevulinic Acid to Extracorporeal Photopheresis in the Treatment of Cutaneous T-Cell Lymphoma: A First-in-Human Phase I/II Study 

    Christensen, Eidi; Foss, Olav A.; Holien, Toril; Juzenas, Petras; Qian, Peng (Journal article; Peer reviewed, 2024)
    Extracorporeal photopheresis (ECP) is a therapeutic modality used for T-cell-mediated disorders. This approach involves exposing isolated white blood cells to photoactivatable 8-methoxypsoralen (8-MOP) and UVA light, aiming ...
  • Omission of Radiotherapy in Primary Mediastinal B-Cell Lymphoma: IELSG37 Trial Results 

    Martelli, Maurizio; Ceriani, Luca; Ciccone, Giovannino; Ricardi, Umberto; Kriachok, Iryna; Botto, Barbara; Balzarotti, Monica; Tucci, Alessandra; Usai, Sara Veronica; Zilioli, Vittorio Ruggero; Pennese, Elsa; Arcaini, Luca; Dabrowska-Iwanicka, Anna; Ferreri, Andrés J.M.; Merli, Francesco; Zhao, Weili; Rigacci, Luigi; Cellini, Claudia; Hodgson, David; Ionescu, Codruta; Minoia, Carla; Lucchini, Elisa; Spina, Michele; Fosså, Alexander; Janikova, Andrea; Cwynarski, Kate; Mikhaeel, George; Jerkeman, Mats; Di Rocco, Alice; Stepanishyna, Yana; Vitolo, Umberto; Santoro, Armando; Re, Alessandro; Puccini, Benedetta; Olivieri, Jacopo; Petrucci, Luigi; Barrington, Sally F.; Malkowski, Bogdan; Metser, Ur; Versari, Annibale; Chauvie, Stephane; Walewski, Jan; Trneny, Marek; Cavalli, Franco; Gospodarowicz, Mary; Johnson, Peter W.M.; Davies, Andrew; Zucca, Emanuele; Kuruvilla, John; Wang, Li; Balada, David; Mocikova, Heidi; Huettmann, Andreas; Angrilli, Francesco; Annibali, Ombretta; Arcaini, Luca; Bagni, Oreste; Battistini, Roberta; Cabras, Maria Giuseppina; Calimeri, Teresa; Catello, Califano; Cavallo, Federica; Ciammella, Patrizia; Consoli, Ugo; De Sanctis, Vitaliana; Di Renzo, Nicola; Fabbri, Alberto; Ferrari, Angela; Flenghi, Leonardo; Gaidano, Gianluca; Gini, Guido; Gotti, Manuel; Guarini, Attilio; Liberati, Anna Marina; Mannina, Donato; Matrone, Fabio; Molinari, Anna Lia; Musuraca, Gerardo; Nassi, Luca; Passamonti, Francesco; Pastore, Domenico; Patti, Caterina; Pelliccia, Sabrina; Piazza, Francesco; Pisani, Francesco; Pizzuti, Michele; Pozzi, Samantha; Ravano, Emanuele; Re, Francesca; Sassone, Marianna; Stefoni, Vittorio; Stelitano, Caterina; Tarantini, Giuseppe; Tarella, Corrado; Vallisa, Daniele; Zaja, Francesco; Zanni, Manuela; Fagerli, Unn Merete; DaSilva, Maria Gomes; Azinwi, Ngwa Che; Deantonio, Letizia; Hitz, Felicitas; Mingrone, Walter; Moccia, Alden; Novak, Urban; Pirosa, Maria Cristina; Stathis, Anastasios; Cozens, Kelly; Fox, Christopher P.; Illidge, Timothy; Johnson, Rod; McKay, Pam; Milne, Alison; Nimish, Shah; Osborne, Wendy; Paneesha, Shankara; Pettitt, Andrew; Stevens, Don Ambrose; Bonomini, Luisella; Ielmini, Nicoletta (Peer reviewed; Journal article, 2024)
    Purpose The role of consolidation radiotherapy in patients with primary mediastinal B-cell lymphoma (PMBCL) is controversial. Methods The IELSG37 trial, a randomized noninferiority study, aimed to assess whether irradiation ...
  • Contactless and continuous monitoring of respiratory rate in a hospital ward: a clinical validation study 

    Toften, Ståle; Kjellstadli, Jonas Tøgersen; Kværness, Jørn; Pedersen, Line; Laugsand, Lars Erik; Thu, Ole Kristian Forstrønen (Journal article; Peer reviewed, 2024)
    Introduction: Continuous monitoring of respiratory rate in hospital wards can provide early detection of clinical deterioration, thereby reducing mortality, reducing transfers to intensive care units, and reducing the ...
  • Healthcare professionals’ experiences of interdisciplinary collaboration in pain centres – A qualitative study 

    Nøst, Torunn Hatlen; Dahl-Michelsen, Tone; Aandahl, Hanne; Steinsbekk, Aslak Irgens (Peer reviewed; Journal article, 2024)
    Objectives: The complexity of chronic pain requires interdisciplinary collaboration. Although this is recognisable in the framework for pain centres, few studies have investigated how interdisciplinary collaboration in ...
  • Exploring the Discrepancy Between Subjective and Objective Measures of Executive Functions in Young Adult Survivors of Childhood Acute Lymphoblastic Leukemia 

    Egset, Kaja Solland; Weider, Siri; Hjemdal, Odin; Ruud, Ellen; Hjort, Magnus Aasved; Eilertsen, Mary-Elizabeth; Sund, Anne Mari; Stubberud, Jan Egil; Reinfjell, Trude (Peer reviewed; Journal article, 2024)
    Purpose: Childhood acute lymphoblastic leukemia (ALL) is associated with executive dysfunction in long-term survivorship. This is evidenced by subjective and objective measures of executive functions (EFs). However, the ...

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