St. Olavs hospital
Recent Submissions
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Decidual and placental NOD1 is associated with inflammation in normal and preeclamptic pregnancies
(Peer reviewed; Journal article, 2021)Introduction: Inflammation is a normal physiological process that increases to harmful levels in preeclampsia. It affects the interaction between maternal immune cells and fetal trophoblasts at both sites of the maternal-fetal ... -
Assessment of the quality of life in parents of children with ADHD : validation of the Multicultural Quality of Life in Norwegian pediatric mental health settings
(Peer reviewed; Journal article, 2021)Background: The brief generic Multicultural Quality of Life Index (MQLI) is a culturally informed self-report 10-item questionnaire used to measure health-related quality of life (QoL). QoL is an important outcome measure ... -
Association between exposure to different stone aggregates from asphalt and blood coagulability: A human exposure chamber study
(Peer reviewed; Journal article, 2021)A large fraction of particulate matter (PM), especially PM10, concentrations are due to non-exhaust emissions, such as road abrasion and wear on tires and brake pads. Concentrating on road abrasion, we aimed to investigate ... -
Assessing the role of genome-wide DNA methylation between smoking and risk of lung cancer using repeated measurements: the HUNT Study
(Peer reviewed; Journal article, 2021)Background: It is unclear if smoking-related DNA methylation represents a causal pathway between smoking and risk of lung cancer. We sought to identify novel smoking-related DNA methylation sites in blood, with repeated ... -
Rhinosinusitis without Nasal Polyps in COPD
(Peer reviewed; Journal article, 2020)The validity of the united airway disease concept for rhinosinusitis (RS) and chronic obstructive pulmonary disease (COPD) has been questioned because of methodological limitations in previous studies. In this study we ... -
Effects of tilt on cerebral hemodynamics measured by NeoDoppler in healthy neonates
(Peer reviewed; Journal article, 2021)Background: Today, there are conflicting descriptions of how neonates respond to tilt. Examining physiologic responses of cerebral blood flow velocities (BFVs) in challenging situations like a tilt requires equipment that ... -
Intraperitoneal insulin administration in pigs: Effect on circulating insulin and glucose levels
(Peer reviewed; Journal article, 2021)Introduction The effect of intraperitoneal insulin infusion has limited evidence in the literature. Therefore, the aim of the study was to investigate the pharmacokinetics and pharmacodynamics of different intraperitoneal ... -
Claims for compensation from women with cervical cancer in Norway-A retrospective, descriptive study of a 12-year period
(Peer reviewed; Journal article, 2020)Introduction: In Norway, all patient-reported claims for compensation are evaluated by The Norwegian System of Patient Injury Compensation (NPE). The number of claims from women with cervical cancer is rising, and the ... -
Right Ventricular Flow Dynamics in Dilated Right Ventricles: Energy Loss Estimation Based on Blood Speckle Tracking Echocardiography-A Pilot Study in Children
(Peer reviewed; Journal article, 2021)Using blood speckle tracking (BST) based on high-frame-rate echocardiography (HFRE), we compared right ventricle (RV) flow dynamics in children with atrial septal defects (ASDs) and repaired tetralogy of Fallot (rTOF). ... -
Asthma and asthma symptom control in relation to incidence of lung cancer in the HUNT study
(Peer reviewed; Journal article, 2021)Large prospective studies on asthma, especially asthma symptom control, as a potential risk factor for lung cancer are limited. We followed up 62,791 cancer-free Norwegian adults from 1995–1997 to 2017. Self-reported ... -
Genetic control of variability in subcortical and intracranial volumes
(Peer reviewed; Journal article, 2020)Sensitivity to external demands is essential for adaptation to dynamic environments, but comes at the cost of increased risk of adverse outcomes when facing poor environmental conditions. Here, we apply a novel methodology ... -
A survey of anaesthesia practices at all hospitals performing caesarean sections in Sierra Leone
(Peer reviewed; Journal article, 2020)Background Providing safe anaesthesia is essential when performing caesarean sections, one of the most commonly performed types of surgery. Anaesthesia‐related causes of maternal mortality are generally considered ... -
Exploring patterns in psychiatric outpatients’ preferences for involvement in decision-making : a latent class analysis approach
(Peer reviewed; Journal article, 2021)Background: Shared decision-making (SDM), a collaborative approach that includes and respects patients’ preferences for involvement in decision-making about their treatment, is increasingly advocated. However, in the ... -
Survival of glioblastoma in relation to tumor location: a statistical tumor atlas of a population-based cohort
(Peer reviewed; Journal article, 2021)Purpose Previous studies on the effect of tumor location on overall survival in glioblastoma have found conflicting results. Based on statistical maps, we sought to explore the effect of tumor location on overall survival ... -
Phosphatase of Regenerating Liver-3 Regulates Cancer Cell Metabolism in Multiple Myeloma
(Peer reviewed; Journal article, 2021)Cancer cells often depend on microenvironment signals from molecules such as cytokines for proliferation and metabolic adaptations. PRL‐3, a cytokine‐induced oncogenic phosphatase, is highly expressed in multiple myeloma ... -
Sonopermeation Enhances Uptake and Therapeutic Effect of Free and Encapsulated Cabazitaxel
(Peer reviewed; Journal article, 2021)Delivery of drugs and nanomedicines to tumors is often heterogeneous and insufficient and, thus, of limited efficacy. Microbubbles in combination with ultrasound have been found to improve delivery to tumors, enhancing ... -
Structural and Pragmatic Language Impairments in Children Evaluated for Autism Spectrum Disorder (ASD)
(Peer reviewed; Journal article, 2021)Pragmatic language impairments are common in neurodevelopmental disorders, especially in autism spectrum disorder (ASD). The relationship between structural language skills and pragmatic competence in children with autistic ... -
The prognostic value of methylation signatures and NF2 mutations in atypical meningiomas
(Peer reviewed; Journal article, 2021)Background: Due to the solely subjective histopathological assessment, the WHO 2016 classification of human meningiomas is subject to interobserver variation. Consequently, the need for more reliable and objective markers ... -
Neural signaling modulates metabolism of gastric cancer
(Peer reviewed; Journal article, 2021)Tumors comprise cancer cells and the associated stromal and immune/inflammatory cells, i.e., tumor microenvironment (TME). Here, we identify a metabolic signature of human and mouse model of gastric cancer and show that ... -
Influenza vaccination and risk for cardiovascular events: a nationwide self-controlled case series study
(Peer reviewed; Journal article, 2021)Background US and European guidelines diverge on whether to vaccinate adults who are not at high risk for cardiovascular events against influenza. Here, we investigated the associations between influenza vaccination and ...