St. Olavs hospital
Recent Submissions
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Interaction between overweight and genotypes of HLA, TCF7L2, and FTO in relation to the risk of latent autoimmune diabetes in adults and type 2 diabetes
(Peer reviewed; Journal article, 2019)Objective We investigated potential interactions between body mass index (BMI) and genotypes of human leukocyte antigen (HLA), TCF7L2-rs7903146, and FTO-rs9939609 in relation to the risk of latent autoimmune diabetes in ... -
The Assistive Device Situation for ALS Patients in Norway
(Peer reviewed; Journal article, 2021)Aims. There are limited analytical descriptions of the assistive device situation in Norway for patients with ALS and other motor neuron diseases. This study is aimed at investigating how patients, caregivers, and healthcare ... -
microRNA-451a prevents activation of matrix metalloproteinases 2 and 9 in human cardiomyocytes during pathological stress stimulation.
(Peer reviewed; Journal article, 2019)Matrix metalloproteinases (MMP) are important for cardiac remodeling. Recently, microRNA (miR)-451a has been found to inhibit the expression of both MMP-2 and MMP-9 in human malignancies, but its role in cardiomyocytes has ... -
Exercise training for patients with type 2 diabetes and cardiovascular disease: What to pursue and how to do it. A Position Paper of the European Association of Preventive Cardiology (EAPC)
(Peer reviewed; Journal article, 2019)Patients with type 2 diabetes mellitus suffer from dysregulation of a plethora of cardiovascular and metabolic functions, including dysglycaemia, dyslipidaemia, arterial hypertension, obesity and a reduced cardiorespiratory ... -
Correlation Between Digital and Manual Determinations of Ki-67/MIB-1 Proliferative Indices in Human Meningiomas
(Peer reviewed; Journal article, 2019)Objective. Proliferative activity in tumor tissues is assessed as the percentage of Ki-67/MIB-1-positive cells, or the proliferative index (PI). The PI is routinely assessed manually. However, the subjectivity of manual ... -
Levator ani muscle morphology and function in women with obstetric anal sphincter injury
(Peer reviewed; Journal article, 2019)Objectives To estimate the prevalence of, and explore the risk factors for, levator ani muscle (LAM) injury in women with clinically diagnosed obstetric anal sphincter injury (OASI). The secondary aim was to assess the ... -
The effect of smoking intensity on all-cause and cause-specific mortality-a Mendelian randomization analysis.
(Peer reviewed; Journal article, 2019)Background Smoking is an important cause of mortality and recent studies have suggested that even low-intensity smoking might be associated with increased mortality. Still, smoking is associated with lower socio-economic ... -
Hysterotomy level at cesarean section and occurrence of large scar defects: a randomized single-blind trial
(Peer reviewed; Journal article, 2019)Objective To study the association between the level of Cesarean hysterotomy and the presence of large uterine scar defects 6–9 months after delivery. Methods This was a two-center, randomized, single-blind trial of ... -
A Compilation of Serum Concentrations of 12 Antipsychotic Drugs in a Therapeutic Drug Monitoring Setting
(Peer reviewed; Journal article, 2019)Background: No comprehensive collection of routine therapeutic drug monitoring data for antipsychotic drugs has been published. Methods: In this compilation, data on 12 antipsychotics are presented. The drugs included ... -
3D ultrasound-guided resection of low-grade gliomas: principles and clinical examples
(Journal article, 2019)3D ultrasound (US) is a convenient tool for guiding the resection of low-grade gliomas, seemingly without deterioration in patients’ quality of life. This article offers an update of the intraoperative workflow and the ... -
Neurotoxic effects of mercury exposure in dental personnel
(Peer reviewed; Journal article, 2019)Numerous studies have reported neurobehavioural effects in dental personnel occupationally exposed to chronic low levels of mercury (Hg). Hg exposure from dental work may also induce various chronic conditions such as ... -
2019 EACTS/EACTA/EBCP guidelines on cardiopulmonary bypass in adult cardiac surgery.
(Peer reviewed; Journal article, 2019) -
Boys and girls differ in symptoms and neurodevelopmental outcome after perinatal metabolic acidosis, a population-based study
(Peer reviewed; Journal article, 2018)Aim To evaluate sex differences in infants born at term with metabolic acidosis with regard to perinatal health and symptomatology, and developmental outcome. Methods From a population-based cohort of infants born at ... -
Quality of life and fear of COVID-19 in 2600 baccalaureate nursing students at five universities: a cross-sectional study
(Peer reviewed; Journal article, 2021)Background The COVID-19 pandemic has caused significant disruptions in the implementation of programs across educational institutions. Nursing students, being both young adults and by practical training, part of the health ... -
The Impact of Vascular Risk Factors on Post-stroke Cognitive Impairment: The Nor-COAST Study
(Peer reviewed; Journal article, 2021)Introduction: Post-stroke cognitive impairment (PSCI) is common, but evidence on the impact of vascular risk factors is lacking. We explored the association between pre-stroke vascular risk factors and PSCI and studied the ... -
Frailty and survival in elderly intensive care patients in Norway
(Journal article; Peer reviewed, 2021)Background Today, 10%-15% of Norwegian intensive care patients are ≥80 years. This proportion will increase significantly over the next 20 years, but it is unlikely that resources for intensive care increase correspondingly. ... -
CSF neurofilament light may predict progression from amnestic mild cognitive impairment to Alzheimer's disease dementia
(Peer reviewed; Journal article, 2021)Neurofilament light (NfL) is a promising biomarker of neurodegeneration in Alzheimer's disease (AD). In this study, cerebrospinal fluid (CSF) NfL was measured in a 24-month longitudinal cohort consisting of control (n = ... -
Short-term outcome after open-heart surgery for severe chronic rheumatic heart disease in a low-income country, with comparison with an historical control group: An observational study
(Peer reviewed; Journal article, 2021)Objectives Rheumatic heart disease (RHD) is a major burden in low-income and middle-income countries (LMICs). Cardiac surgery is the only curative treatment. Little is known about patients with severe chronic RHD operated ... -
The fat mass and obesity-associated (FTO) gene allele rs9939609 and glucose tolerance, hepatic and total insulin sensitivity, in adults with obesity
(Peer reviewed; Journal article, 2021)The objective of the study was to assess associations of the rs9939609 FTO allele to glucose tolerance, hepatic and total insulin sensitivity (IS) in individuals with obesity. From a low-dose hyperinsulinemic euglycemic ... -
Dyspnea, lung function and CT findings three months after hospital admission for COVID-19
(Peer reviewed; Journal article, 2020)The long-term pulmonary outcomes of coronavirus disease 2019 (COVID-19) are unknown. We aimed to describe self-reported dyspnoea, quality of life, pulmonary function, and chest CT findings three months following hospital ...
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