• Genetic architecture of subcortical brain structures in 38,851 individuals 

  Satizabal, Claudia L.; Adams, Hieab H.H.; Hibar, Derrek; White, Charles C.; Knol, Maria J.; Stein, Jason L.; Scholz, Markus; Sargurupremraj, Muralidharan; Jahanshad, Neda; Roshchupkin, Gennady V.; Smith, Albert V.; Bis, Joshua C.; Jian, Xueqiu; Luciano, Michelle; Hofer, Edith; Teumer, Alexander; van der Lee, Sven J.; Yang, Jingyun; Yanek, Lisa R.; Lee, Tom V.; Li, Shuo; Hu, Yanhui; Koh, Jia Yu; Eicher, John D.; Desrivières, Sylvane; Arias-Vasquez, Alejandro; Chauhan, Ganesh; Athanasiu, Lavinia; Rentería, Miguel E.; Kim, Sungeun; Hoehn, David; Armstrong, Nicola J.; Chen, Qiang; Holmes, Avram J.; den Braber, Anouk; Kloszewska, Iwona; Andersson, Micael; Espeseth, Thomas; Grimm, Oliver; Abramovic, Lucija; Alhusaini, Saud; Milaneschi, Yuri; Papmeyer, Martina; Axelsson, Tomas; Ehrlich, Stefan; Roiz-Santiáñez, Roberto; Kraemer, Bernd; Håberg, Asta; Jones, Hannah J; Pike, G. Bruce; Stein, Dan J.; Stevens, Allison; Bralten, Janita; Vernooij, Meike W.; Harris, Tamara B.; Filippi, Irina; Witte, A Veronica; Guadalupe, Tulio; Wittfeld, Katharina; Mosley, Thomas H.; Becker, James T.; Doan, Nhat Trung; Hagenaars, Saskia P.; Saba, Yasaman; Cuellar-Partida, Gabriel; Amin, Najaf; Hilal, Saima; Nho, Kwangsik; Mirza-Schreiber, Nazanin; Arfanakis, Konstantinos; Becker, Diane M.; Ames, David; Goldman, Aaron L.; Lee, Phil H.; Boomsma, Dorret I.; Lovestone, Simon; Giddaluru, Sudheer; Le Hellard, Stephanie; Mattheisen, Manuel; Bohlken, Marc M.; Kasperaviciute, Dalia; Schmaal, Lianne; Lawrie, Stephen M.; Agartz, Ingrid; Walton, Esther; Tordesillas-Gutierrez, Diana; Davies, Gareth E.; Shin, Jean; Ipser, Jonathan C.; Vinke, Louis N.; Hoogman, Martine; Jia, Tianye; Burkhardt, Ralph; Klein, Marieke; Crivello, Fabrice; Janowitz, Deborah; Carmichael, Owen; Haukvik, Unn Kristin H.; Aribisala, Benjamin S.; Schmidt, Helena; Strike, Lachlan T.; Cheng, Ching-Yu; Risacher, Shannon L.; Putz, Benno; Fleischman, Debra A.; Assareh, Amelia A.; Mattay, Venkata S.; Buckner, Randy L.; Mecocci, Patrizia; Dale, Anders; Cichon, Sven; Boks, Marco P.; Matarin, Mar; Penninx, Brenda W.J.H.; Calhoun, Vince D.; Chakravarty, M. Mallar; Marquand, André F.; Macare, Christine; Kharabian Masouleh, Shahrzad; Oosterlaan, Jaap; Amouyel, Philippe; Hegenscheid, Katrin; Rotter, Jerome I.; Schork, Andrew J.; Liewald, David C.M.; de Zubicaray, Greig I.; Wong, Tien Yin; Shen, Li; Sämann, Philipp G.; Brodaty, Henry; Roffman, Joshua L.; de Geus, Eco J.C.; Tsolaki, Magda; Erk, Susanne; van Eijk, Kristel R.; Cavalleri, Gianpiero L.; Van Der Wee, Nic J.A.; McIntosh, Andrew M.; Gollub, Randy L.; Bulayeva, Kazima B.; Bernard, Manon; Richards, Jennifer S.; Himali, Jayandra J.; Loeffler, Markus; Rommelse, Nanda; Hoffmann, Wolfgang; Westlye, Lars Tjelta; Valdés Hernández, Maria C.; Hansell, Narelle K.; van Erp, Theo G.M.; Wolf, Christiane; Kwok, John B.J.; Vellas, Bruno; Heinz, Andreas; Olde Loohuis, Loes M.; Delanty, Norman; Ho, Beng-Choon; Ching, Christopher R.K.; Shumskaya, Elena; Singh, Baljeet; Hofman, Albert; van der Meer, Dennis; Homuth, Georg; Psaty, Bruce M.; Bastin, Mark E.; Montgomery, Grant W.; Foroud, Tatiana M.; Reppermund, Simone; Hottenga, Jouke-Jan; Simmons, Andrew; Meyer-Lindenberg, Andreas; Cahn, Wiepke; Whelan, Christopher D; van Donkelaar, Marjolein M.J.; Yang, Qiong; Hosten, Norbert; Green, Robert C.; Thalamuthu, Anbupalam; Mohnke, Sebastian; Hulshoff Pol, Hilleke E.; Lin, Honghuang; Jack, Clifford R.; Schofield, Peter R.; Mühleisen, Thomas W.; Maillard, Pauline; Potkin, Steven G.; Wen, Wei; Fletcher, Evan; Toga, Arthur W.; Gruber, Oliver; Huentelman, Matthew; Davey Smith, George; Launer, Lenore J.; Nyberg, Lars; Jönsson, Erik Gunnar; Crespo-Facorro, Benedicto; Koen, Nastassja; Greve, Douglas N.; Uitterlinden, André G.; Weinberger, Daniel R.; Steen, Vidar Martin; Fedko, Iryna O.; Groenewold, Nynke A.; Niessen, Wiro J.; Toro, Roberto; Tzourio, Christophe; Longstreth, William T.; Ikram, M. Kamran; Smoller, Jordan W.; van Tol, Marie-Jose; Sussmann, Jessika E.; Paus, Tomáš; Lemaître, Hervé; Schroeter, Matthias L.; Mazoyer, Bernard; Andreassen, Ole Andreas; Holsboer, Florian; Depondt, Chantal; Veltman, Dick J.; Turner, Jessica A.; Pausova, Zdenka; Schumann, Gunter; van Rooij, Daan; Djurovic, Srdjan; Deary, Ian J.; McMahon, Katie L; Müller-Myhsok, Bertram; Brouwer, Rachel M.; Soininen, Hilkka; Pandolfo, Massimo; Wassink, Thomas H.; Cheung, Joshua W.; Wolfers, Thomas; Martinot, Jean-Luc; Zwiers, Marcel P.; Nauck, Matthias; Melle, Ingrid; Martin, Nicholas G.; Kanai, Ryota; Westman, Eric; Kahn, René S.; Sisodiya, Sanjay M.; White, Tonya; Saremi, Arvin; van Bokhoven, Hans; Brunner, Han G.; Völzke, Henry; Wright, Margaret J.; van `t Ent, Dennis; Nöthen, Markus M.; Ophoff, Roel A.; Buitelaar, Jan K.; Fernandéz, Guillén; Sachdev, Perminder S.; Rietschel, Marcella; van Haren, Neeltje E.M.; Fisher, Simon E.; Beiser, Alexa S.; Francks, Clyde; Saykin, Andrew J.; Mather, Karen A.; Romanczuk-Seiferth, Nina; Hartman, Catharina A.; DeStefano, Anita L; Heslenfeld, Dirk J.; Weiner, Michael W.; Walter, Henrik; Hoekstra, Pieter J.; Nyquist, Paul A.; Franke, Barbara; Bennett, David A.; Grabe, Hans J.; Johnson, Andrew D.; Chen, Christopher; van Duijn, Cornelia M.; Lopez, Oscar L.; Fornage, Myriam; Wardlaw, Joanna M.; Schmidt, Reinhold; DeCarli, Charles; De Jager, Philip L.; Villringer, Arno; Debette, Stéphanie; Gudnason, Vilmundur; Medland, Sarah E.; Shulman, Joshua M.; Thompson, Paul M.; Seshadri, Sudha; Ikram, M. Arfan (Journal article, 2019)

  Subcortical brain structures are integral to motion, consciousness, emotions and learning. We identified common genetic variation related to the volumes of the nucleus accumbens, amygdala, brainstem, caudate nucleus, globus ...

• Circulating microRNAs as predictive biomarkers of myocardial infarction: Evidence from the HUNT study. 

  Velle-Forbord, Torbjørn; Eidlaug, Maria; Debik, Julia Barbara; Sæther, Julie Caroline; Follestad, Turid; Nauman, Javaid; Gigante, Bruna; Røsjø, Helge; Omland, Torbjørn; Langaas, Mette; Bye, Anja (Peer reviewed; Journal article, 2019)

  Background and aims Several risk prediction models for coronary heart disease (CHD) are available today, however, they only explain a modest proportion of the incidence. Circulating microRNAs (miRs) have recently been ...

• Airway segmentation and centerline extraction from thoracic CT - Comparison of a new method to state of the art commercialized methods 

  Reynisson, Pall Jens; Scali, Marta; Smistad, Erik; Hofstad, Erlend Fagertun; Leira, Håkon Olav; Lindseth, Frank; Hernes, Toril A. Nagelhus; Amundsen, Tore; Sorger, Hanne; Langø, Thomas (Peer reviewed; Journal article, 2015)

  Introduction Our motivation is increased bronchoscopic diagnostic yield and optimized preparation, for navigated bronchoscopy. In navigated bronchoscopy, virtual 3D airway visualization is often used to guide a bronchoscopic ...

• Innate immune signalling genetics of pain, cognitive dysfunction and sickness symptoms in cancer pain patients treated with transdermal fentanyl 

  Barratt, Daniel T.; Klepstad, Pål; Dale, Ola; Kaasa, Stein; Somogyi, Andrew A. (Peer reviewed; Journal article, 2015)

  Common adverse symptoms of cancer and chemotherapy are a major health burden; chief among these is pain, with opioids including transdermal fentanyl the mainstay of treatment. Innate immune activation has been implicated ...

• Life after adolescent and adult moderate and severe traumatic brain injury: self-reported executive, emotional, and behavioural function 2-5 years after injury 

  Finnanger, Torun Gangaune; Olsen, Alexander; Skandsen, Toril; Lydersen, Stian; Vik, Anne; Evensen, Kari A. Indredavik; Catroppa, Cathy; Håberg, Asta; Andersson, Stein; Indredavik, Marit Sæbø (Peer reviewed; Journal article, 2015)

  Survivors of moderate-severe Traumatic Brain Injury (TBI) are at risk for long-term cognitive, emotional, and behaviouralproblems. This prospective cohort study investigated self-reported executive, emotional, and behavioural ...

• Norwegian constraint-induced therapy multisite trial: Adherence to treatment protocol applied early after stroke 

  Stock, Roland; Thrane, Gyrd; Askim, Torunn; Karlsen, Gunn Marte; Langørgen, Eli; Erichsen, Anne Spendrup; Gjone, Ragna Ingeborg; Anke, Audny (Peer reviewed; Journal article, 2015)

  Objective: To investigate to what degree patients adhered to a modified constraint-induced movement therapy protocol, and to explore factors associated with the results. Design: Prospective follow-up of the intervention ...

• Serum and urine concentrations of morphine and morphine metabolites in patients with advanced cancer receiving continuous intravenous morphine: An observational study Cancer palliative care 

  Lee, Yong Joo; Suh, Sang-Yeon; Song, Junghan; Lee, Sanghee Shiny; Seo, Ah-Ram; Ahn, Hong-Yup; Lee, Myung Ah; Kim, Chul-Min; Klepstad, Pål (Peer reviewed; Journal article, 2015)

  Background:The feasibility and clinical implication of drug monitoring of morphine, morphine-6-glucuronide (M6G)and morphine-3-glucuronide (M3G) need further investigation. This study aimed to determine what predicts ...

• A randomized study of the effect of patient positioning on setup reproducibility and dose distribution to organs at risk in radiotherapy of rectal cancer patients 

  Frøseth, Trude Camilla Salvesen; Strickert, Trond; Solli, Kjersti Sund; Salvesen, Øyvind; Frykholm, Gunilla; Reidunsdatter, Randi Johansen (Peer reviewed; Journal article, 2015)

  Background:The patient positioning in pelvic radiotherapy (RT) should be decided based on both reproducibilityand on which position that yields the lowest radiation dose to the organs at risk (OAR), and thereby less ...

• Association between pulmonary function and peak oxygen uptake in elderly: the Generation 100 study 

  Hassel, Erlend; Stensvold, Dorthe; Halvorsen, Thomas; Wisløff, Ulrik; Langhammer, Arnulf; Steinshamn, Sigurd Loe (Peer reviewed; Journal article, 2015)

  Background Although reduced function of the respiratory system limits peak oxygen uptake in diseases affecting the lungs or airways, the healthy respiratory system is thought to have a spare capacity for oxygen transport ...

• Identification of gait domains and key gait variables following hip fracture 

  Thingstad, Pernille; Egerton, Thorlene; Ihlen, Espen Alexander F.; Taraldsen, Kristin; Moe-Nilssen, Rolf; Helbostad, Jorunn L. (Peer reviewed; Journal article, 2015)

  Background:Restoration of gait is an important goal of rehabilitation after hip fracture. Numerous spatial andtemporal gait variables have been reported in the literature, but beyond gait speed, there is little agreement ...

• How to Be 80 Year Old and Have a VO2max of a 35 Year Old 

  Karlsen, Trine; Leinan, Ingeborg Megård; Bækkerud, Fredrik Hjulstad; Lundgren, Kari Margrethe; Tari, Atefe R; Steinshamn, Sigurd Loe; Støylen, Asbjørn; Rognmo, Øivind (Peer reviewed; Journal article, 2015)

  Background. To discuss the cardiovascular and pulmonary physiology and common risk factors of an 80-year-old man with a world record maximal oxygen uptake of 50 mL·kg−1·min−1. Methods. Case report. Results. His maximal ...

• ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries 

  Thompson, Paul M.; Jahanshad, Neda; Ching, Christopher R.K.; Salminen, Lauren E.; Thomopoulos, Sophia I.; Bright, Joanna; Baune, Bernhard T.; Bertolin, Sara; Bralten, Janita; Bruin, Willem B.; Bulow, Robin; Chen, Jian; Chye, Yann; Dannlowski, Udo; de Kovel, Carolien G.F.; Donohoe, Gary; Eyler, Lisa T.; Faraone, Stephen V.; Favre, Pauline; Filippi, Courtney A.; Frodl, Thomas; Garijo, Daniel; Gil, Yolanda; Grabe, Hans J.; Grasby, Katrina L.; Hajek, Tomas; Han, Laura K.M.; Hatton, Sean N.; Hilbert, Kevin; Ho, Tiffany C.; Holleran, Laurena; Homuth, Georg; Hosten, Norbert; Houenou, Josselin; Ivanov, Iliyan; Jia, Tianye; Kelly, Sinead; Klein, Marieke; Kwon, Jun Soo; Laansma, Max A.; Leerssen, Jeanne; Lueken, Ulrike; Nunes, Abraham; O'Neill, Joseph; Opel, Nils; Piras, Fabrizio; Piras, Federica; Postema, Merel C.; Pozzi, Elena; Shatokhina, Natalia; Soriano-Mas, Carles; Spalletta, Gianfranco; Sun, Daqiang; Teumer, Alexander; Tilot, Amanda K.; Tozzi, Leonardo; van der Merwe, Celia; van Someren, Eus J.W.; van Wingen, Guido A.; Völzke, Henry; Walton, Esther; Wang, Lei; Winkler, Anderson M.; Wittfeld, Katharina; Wright, Margaret J.; Yun, Je-Yeon; Zhang, Guohao; Zhang-James, Yanli; Adhikari, Bhim M.; Agartz, Ingrid; Aghajani, Moji; Aleman, André; Althoff, Robert R.; Altmann, Andre; Andreassen, Ole Andreas; Baron, David A.; Bartnik-Olson, Brenda L.; Bas-Hoogendam, Janna Marie; Baskin-Sommers, Arielle R.; Bearden, Carrie E.; Berner, Laura A.; Boedhoe, Premika S.W.; Brouwer, Rachel M.; Buitelaar, Jan K.; Caeyenberghs, Karen; Cecil, Charlotte A.M.; Cohen, Ronald A.; Cole, James H.; Conrod, Patricia J.; De Brito, Stephane A.; de Zwarte, Sonja M.C.; Dennis, Emily L.; Desrivieres, Sylvane; Dima, Danai; Ehrlich, Stefan; Esopenko, Carrie; Fairchild, Graeme; Fisher, Simon E.; Fouche, Jean-Paul; Francks, Clyde; Frangou, Sophia; Franke, Barbara; Garavan, Hugh P.; Glahn, David C.; Groenewold, Nynke A.; Gurholt, Tiril Pedersen; Gutman, Boris A.; Hahn, Tim; Harding, Ian H.; Hernaus, Dennis; Hibar, Derrek P.; Hillary, Frank G.; Hoogman, Martine; Hulshoff Pol, Hilleke E.; Jalbrzikowski, Maria; Karkashadze, George A.; Klapwijk, Eduard T.; Knickmeyer, Rebecca C.; Kochunov, Peter; Koerte, Inga K.; Kong, Xiang-Zhen; Liew, Sook-Lei; Lin, Alexander P.; Logue, Mark W.; Luders, Eileen; Macciardi, Fabio; Mackey, Scott; Mayer, Andrew R.; McDonald, Carrie R.; McMahon, Agnes B.; Medland, Sarah E.; Modinos, Gemma; Morey, Rajendra A.; Mueller, Sven C.; Mukherjee, Pratik; Namazova-Baranova, Leyla; Nir, Talia M; Olsen, Alexander; Paschou, Peristera; Pine, Daniel S.; Pizzagalli, Fabrizio; Rentería, Miguel E.; Rohrer, Jonathan D.; Sämann, Philipp G.; Schmaal, Lianne; Schumann, Gunter; Shiroishi, Mark S.; Sisodiya, Sanjay M.; Smit, Dirk J.A.; Sønderby, Ida Elken; Stein, Dan J.; Stein, Jason L.; Tahmasian, Masoud; Tate, David F.; Turner, Jessica A.; van den Heuvel, Odile A; Van Der Wee, Nic J.A.; van der Werf, Ysbrand D.; van Erp, Theo G.M.; van Haren, Neeltje E.M.; van Rooij, Daan; van Velzen, Laura S.; Veer, Ilya M.; Veltman, Dick J.; Villalon-Reina, Julio E.; Walter, Henrik; Whelan, Christopher D.; Wilde, Elisabeth A.; Zarei, Mojtaba; Zelman, Vladimir (Peer reviewed; Journal article, 2020)

  This review summarizes the last decade of work by the ENIGMA (Enhancing NeuroImaging Genetics through Meta Analysis) Consortium, a global alliance of over 1400 scientists across 43 countries, studying the human brain in ...

• Progressive multifocal leukoencephalopathy in an immunocompetent patient? 

  Johansen, Krisztina; Torp, Sverre Helge; Rydland, Jana; Aasly, Jan (Peer reviewed; Journal article, 2013)

  Background: Progressive multifocal leukoencephalopathy (PML) is a rapidly progressive, potentially fatal, demyelinating disease affecting immunosuppressed patients. PML is rarely reported in cases with no underlying disease ...

• A new removable airway stent 

  Amundsen, Tore; Sørhaug, Sveinung; Leira, Håkon Olav; Tyvold, Stig Sverre; Langø, Thomas; Hammer, Tommy Arild; Manstad-Hulaas, Frode; Mattsson, Erney (Peer reviewed; Journal article, 2016)

  Background Malignant airway obstruction is a feared complication and will most probably occur more frequently in the future because of increasing cancer incidence and increased life expectancy in cancer patients. Minimal ...

• Maximal strength training as a physical rehabilitation for patients with substance use disorder; a randomized controlled trial 

  Unhjem, Runar Jakobsen; Flemmen, Grete; Hoff, Jan; Wang, Eivind (Peer reviewed; Journal article, 2016)

  Background:Patients with substance use disorder (SUD) suffer from multiple health and psychosocial problems.Because poor physical capacities following an inactive lifestyle may indeed contribute to these problems, ...

• Lynch syndrome mutation spectrum in New South Wales, Australia, including 55 novel mutations 

  Sjursen, Wenche; McPhillips, Mary; Scott, Rodney J.; Talseth-Palmer, Bente (Peer reviewed; Journal article, 2016)

  Background Lynch syndrome, the most frequent hereditary colorectal cancer syndrome, is caused by defects in mismatch repair genes. Genetic testing is important in order to identify mutation carriers who can benefit from ...

• Quantitative comparison of PET performance-Siemens Biograph mCT and mMR 

  Karlberg, Anna Maria; Sæther, Oddbjørn; Eikenes, Live; Goa, Pål Erik (Peer reviewed; Journal article, 2016)

  Background: Integrated clinical whole-body PET/MR systems were introduced in2010. In order to bring this technology into clinical usage, it is of great importance to compare the performance with the well-established PET/CT. ...

• Habilitering for voksne i spesialisthelsetjenesten: Utvikling og utprøving av brukerundersøkelse 

  Søndenaa, Erik; Sauarlia, Stein Ketil; Hukkelås, Britt; Jullumstrø, Sidsel (Peer reviewed; Journal article, 2016)

  Habilitation specialist service for adults in Sør-Trøndelag has developed and implemented a model for user perceptions over the last five years. As users of the service consist of diverted parts, the work has aimed at ...

• NR4A2 is regulated by Gastrin and involved in gastrin-induced migration and invasion of gastric adenocarcinoma cells 

  Misund, Kristine; Selvik, Linn-Karina M.; Rao, Shalini; Nørsett, Kristin Gabestad; Bakke, Ingunn; Sandvik, Arne; Lægreid, Astrid; Bruland, Torunn; Prestvik, Wenche S; Thommesen, Liv (Peer reviewed; Journal article, 2013)

  The peptide hormone gastrin is known to play a role in differentiation, growth and apoptosis of cells in the gastric mucosa. In this study we demonstrate that gastrin induces Nuclear Receptor 4A2 (NR4A2) expression in the ...

• Placental inflammation by HMGB1 activation of TLR4 at the syncytium 

  Tangerås, Line Haugstad; Silva, Gabriela; Stødle, Guro; Gierman, Lobke; Skei, Bente; Collett, Karin; Beversmark, Anne Lise; Skråstad, Ragnhild Bergene; Thomsen, Liv Cecilie Vestrheim; Bjørge, Line; Iversen, Ann-Charlotte (Peer reviewed; Journal article, 2018)

  Introduction: Normal pregnancy is characterized by an elevated inflammatory state involving the placenta. The placental inflammation is further increased in preeclampsia, resulting in release of harmful danger signals ...

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