• Incidence of invasive Group B Streptococcal infection and the risk of infant death and cerebral palsy: a Norwegian Cohort Study 

  Mynarek, Maren; Bjellmo, Solveig; Lydersen, Stian; Afset, Jan Egil; Andersen, Guro Lillemoen; Vik, Torstein (Peer reviewed; Journal article, 2020)

  Background Group B Streptococcus (GBS) is the leading cause of invasive neonatal infection worldwide. In high-income countries mortality rates are 4–10%, and among survivors of GBS meningitis 30–50% have neurodevelopmental ...

• Discrimination of Breast Cancer from Healthy Breast Tissue Using a Three-component Diffusion-weighted MRI Model 

  Andreassen, Maren Marie Sjaastad; Rodriguez-Soto, Ana; Conlin, CC; Vidić, I; Seibert, TM; Wallace, AM; Zare, S; Kuperman, J; Abudu, B; Ahn, GS; Hahn, M; Jerome, Neil Peter; Østlie, Agnes; Bathen, Tone Frost; Ojeda-Fournier, H; Goa, Pål Erik; Rakow-Penner, Rebecca; Dale, AM (Peer reviewed; Journal article, 2020)

  Purpose: Diffusion-weighted MRI (DW-MRI) is a contrast-free modality that has demonstrated ability to discriminate between predefined benign and malignant breast lesions. However, how well DW-MRI discriminates cancer from ...

• Cerebrospinal fluid sTREM2 in Alzheimer’s disease: comparisons between clinical presentation and AT classification 

  Knapskog, Anne Brita; Henjum, Kristi; Idland, Ane-Victoria; Eldholm, Rannveig Sakshaug; Persson, Karin Ester Torun; Saltvedt, Ingvild; Watne, Leiv; Engedal, Knut; Nilsson, Lars N.G. (Peer reviewed; Journal article, 2020)

  Triggering receptor expressed on myeloid cells 2 (TREM2) is an innate immune receptor expressed by microglia. Its cleaved fragments, soluble TREM2 (sTREM2), can be measured in the cerebrospinal fluid (CSF). Previous studies ...

• Mer fysikalsk behandling og mindre kirurgi for pasienter med skuldersmerte. Virkningen av behandlingen, kunnskapshullene og veien videre. 

  Røe, Yngve; Granviken, Fredrik; Bentsen, Lennart; Kenneth, Chance-Larsen; Fersum, Kjartan; Major, Daniel Høgli (Peer reviewed; Journal article, 2020)

  Innledning: Skuldersmerte er en vanlig og ofte langvarig muskelskjelettplage. Subakromial smerte utgjør den klart største diagnostiske gruppen. I nye faglige retningslinjer frarådes den mest vanlige formen for skulderkirurgi; ...

• Longterm Outcomes of Temporomandibular Joints in Juvenile Idiopathic Arthritis: 17 Years of Followup of a Nordic Juvenile Idiopathic Arthritis Cohort. 

  Glerup, Mia; Stoustrup, Peter Bangsgaard; Matzen, Louise Hauge; Rypdal, Veronika Gjertsen; Nordal, Ellen Berit; Frid, Paula; Arnstad, Ellen Dalen; Rygg, Marite; Thorarensen, Olafur; Ekelund, Maria; Berntson, Lillemor; Fasth, Anders; Nilsson, H; Peltoniemi, Suvi; Aalto, Kristiina; Arte, Sirpa; Toftedal, Peter; Nielsen, Susan; Kreiborg, S.; Herlin, T; Pedersen, T. (Peer reviewed; Journal article, 2020)

  Objective. To determine the prevalence of orofacial symptoms, dysfunctions, and deformities of the temporomandibular joint (TMJ) in juvenile idiopathic arthritis (JIA) 17 years after disease onset. Methods. Drawn from ...

• Identification of novel genetic variants associated with cardiorespiratory fitness 

  Bye, Anja; Klevjer, Marie; Ryeng, Einar; Silva, Gustavo Jose Justo; Moreira, Jose Bianco Nascimento; Stensvold, Dorthe; Wisløff, Ulrik (Peer reviewed; Journal article, 2020)

  Introduction Low maximal oxygen uptake (VO2max) is a strong and independent risk factor for all-cause and cardiovascular disease (CVD) mortality. For other CVD risk factors, numerous genetic association studies have been ...

• Genetic interaction between the non‐homologous end joining factors during B and T lymphocyte development: in vivo mouse models 

  Castaneda Zegarra, Sergio Miguel; Fernandez Berrocal, Marion Silvana; Tkachev, Max; Yao, Rouan; Esnardo Upfold, Nikki Lyn; Oksenych, Valentyn (Peer reviewed; Journal article, 2020)

  Non-homologous end joining (NHEJ) is the main DNA repair mechanism for the repair of double-strand breaks (DSBs) throughout the course of the cell cycle. DSBs are generated in developing B and T lymphocytes during V(D)J ...

• Early gut fungal and bacterial microbiota and childhood growth 

  Schei, Kasper; Simpson, Melanie Rae; Avershina, Ekaterina; Rudi, Knut; Øien, Torbjørn; Juliusson, Petur Benedikt; Underhill, David; Salamati, Saideh; Ødegård, Rønnaug (Peer reviewed; Journal article, 2020)

  Introduction: Childhood growth is a sensitive marker of health. Animal studies show increased height and weight velocity in the presence of fungal as well as antibiotic supplement in feed. Human studies on early gut ...

• Dietary changes in early-stage breast cancer patients from pre-surgery and over the 12 months post-surgery 

  Brunvoll, Sonja Hjellegjerde; Thune, Inger; Bertheussen, Gro Falkener; Fjeldheim, Frøydis Nyborg; Flote, Vidar Gordon; Frydenberg, Hanne; Lundgren, Steinar; Skjerven, Helle; Lømo, Jon; Fagerland, Morten; McTiernan, Anne; Schlichting, Ellen; Hjartåker, Anette (Peer reviewed; Journal article, 2020)

  The time after a breast cancer diagnosis is a potential period for making positive dietary changes, but previous results are conflicting. The main aim of the present study was to study breast cancer patients’ dietary changes ...

• Developmental Course and Risk Factors of Physical Aggression in Late Adolescence 

  Henriksen, Marit; Skrove, Marit Synnøve; Hoftun, Gry Børmark; Sund, Erik; Lydersen, Stian; Tseng, Wan-Ling; Sukhodolsky, Denis G. (Peer reviewed; Journal article, 2020)

  This study examined risk factors of physical aggression during transition from early to late adolescence using a two-wave longitudinal study. Specifically, we examined if risk factors in early adolescence predict physically ...

• Developing Cognition Endpoints for the CENTER-TBI Neuropsychological Test Battery 

  Stenberg, Jonas; Karr, Justin E.; Terry, Douglas P.; Saksvik, Simen Berg; Vik, Anne; Skandsen, Toril; Silverberg, Noah D.; Iverson, Grant L. (Peer reviewed; Journal article, 2020)

  Background: Measuring cognitive functioning is common in traumatic brain injury (TBI) research, but no universally accepted method for combining several neuropsychological test scores into composite, or summary, scores ...

• The complex genetic landscape of familial MDS and AML reveals pathogenic germline variants 

  Rio-Machin, Ana; Villiamy, Tom; Hug, Nele; Walne, Amanda; Tawana, Kiran; Cardoso, Shirleny; Ellison, Alicia; Pontikos, Nikolas; Wang, Jun; Tummala, Hemanth; Al Seraihi, Ahad Fahad H.; Alnajar, Jenna; Bewicke-Copley, Findlay; Barnett, Michael; Armes, Hannah; Bloor, Adrian; Bödör, Csabo; Bowen, David; Fenaux, Pierre; Green, Andrew; Hallahan, Andrew; Hjorth-Hansen, Henrik; Hossein, Upal; Killick, Sally; Lawson, Sarah; Layton, Mark; Male, Alison M.; Marsh, Judith; Mehta, Priyanka; Mous, Rogier; Nomdedéu, Josep F.; Owen, Carolyn; Pavlu, Jiri; Payne, Elspeth; Protheroe, Rachel E.; Preudhomme, Claude; Pujol-Moix, Nuria; Renneville, Aline; Russell, Nigel; Saggar, Anand; Sciuccati, Gabriela; Taussig, David; Toze, Cynthia; Uyttebroeck, Anne; Vandenberghe, Peter; Schlegelberger, Brigitte; Ripperger, Tim; Steinemann, Doris; Wu, John; Mason, Joanne; Page, Paula; Akiki, Susanna; Reay, Kim; Cavenagh, Jamie D.; Plagnol, Vincent; Caceres, Javier F.; Fitzgibbon, Jude; Dokal, Inderjeet (Peer reviewed; Journal article, 2020)

  The inclusion of familial myeloid malignancies as a separate disease entity in the revised WHO classification has renewed efforts to improve the recognition and management of this group of at risk individuals. Here we ...

• Surgery for Extraforaminal Lumbar Disc Herniation: A Single Center Comparative Observational Study 

  Polak, Samuel B.; Madsbu, Mattis Aleksander; Vangen-Lønne, Vetle; Salvesen, Øyvind; Nygaard, Øystein Petter; Solberg, Tore; Vleggeert-Lankamp, Carmen L. A. M.; Gulati, Sasha (Peer reviewed; Journal article, 2020)

  Background Surgery on extraforaminal lumbar disc herniation (ELDH) is a commonly performed procedure. Operating on this type of herniation is known to come with more difficulties than on the frequently seen paramedian ...

• Surgery for herniated lumbar disc in private vs public hospitals: A pragmatic comparative effectiveness study 

  Madsbu, Mattis Aleksander; Salvesen, Øyvind; Carlsen, Sven Magnus; Westin, Steinar; Onarheim, Kristian; Nygaard, Øystein Petter; Solberg, Tore; Gulati, Sasha (Peer reviewed; Journal article, 2020)

  Background There is limited evidence on the comparative performance of private and public healthcare. Our aim was to compare outcomes following surgery for lumbar disc herniation (LDH) in private versus public hospitals. ...

• Comparison of methods to construct a genetic risk score for prediction of rheumatoid arthritis in the population-based Nord-Trøndelag Health Study, Norway 

  Rostami, Sina; Hoff, Mari; Brown, Matthew A.; Hveem, Kristian; Videm, Vibeke (Peer reviewed; Journal article, 2020)

  Objectives: To evaluate selection methods among published single-nucleotide polymorphisms (SNPs) associated with RA to construct predictive genetic risk scores (GRSs) in a population-based setting. Methods: The Nord-Trøndelag ...

• A high cerebrospinal fluid soluble TREM2 level is associated with slow clinical progression of Alzheimer's disease 

  Edwin, Trine Holt; Henjum, Kristi; Nilsson, Lars N. G.; Watne, Leiv; Persson, Karin Ester Torun; Eldholm, Rannveig Sakshaug; Saltvedt, Ingvild; Halaas, Nathalie Bodd; Selbæk, Geir; Engedal, Knut; Strand, Bjørn Heine; Knapskog, Anne Brita (Peer reviewed; Journal article, 2020)

  Introduction: The progression rate of Alzheimer's disease (AD) varies and might be affected by the triggering receptor expressed on myeloid cells (TREM2) activity. We explored if cerebrospinal fluid (CSF) soluble TREM2 ...

• Pediatric Patients in a Local Nepali Emergency Department: Presenting Complaints, Triage and Post-Discharge Mortality 

  Giri, Samita; Halvas-Svendsen, Tine; Rogne, Tormod; Shrestha, Sanu Krishna; Døllner, Henrik; Solligård, Erik; Risnes, Kari (Peer reviewed; Journal article, 2020)

  Background. In low-income countries, pediatric emergency care is largely underdeveloped although child mortality in emergency care is more than twice that of adults, and mortality after discharge is high. Aim. We aimed at ...

• Do Childhood Boarding School Experiences Predict Health, Well-Being and Disability Pension in Adults? A SAMINOR Study 

  Friborg, Oddgeir; Sørlie, Tore; Schei, Berit; Javo, Cecilie; Sørbye, Øystein; Hansen, Ketil Lenert (Peer reviewed; Journal article, 2020)

  Indigenous Sámi and Kven minority children in Norway were during the 20th century placed at boarding schools to hasten their adoption of the Norwegian majority language and culture. This is the first population-based study ...

• Frequency of fatigue and its changes in the first 6 months after traumatic brain injury: results from the CENTER-TBI study 

  Andelic, Nada; Røe, Cecilie; Brunborg, Cathrine; Zeldovich, Marina; Løvstad, Marianne; Løke, Daniel; Borgen, Ida Maria Henriksen; Voormolen, Daphne; Howe, Emilie; Forslund, Marit Vindal; DAHL, HILDE MARGRETE; von Steinbuechel, Nicole; Helseth, Eirik; Røise, Olav; Frisvold, Shirin; Anke, Audny; Skandsen, Toril; Vik, Anne (Peer reviewed; Journal article, 2020)

  Background Fatigue is one of the most commonly reported subjective symptoms following traumatic brain injury (TBI). The aims were to assess frequency of fatigue over the first 6 months after TBI, and examine whether fatigue ...

• Exercise and nutrition interventions in patients with head and neck cancer during curative treatment: A systematic review and meta-analysis 

  Bye, Asta; Sandmæl, Jon Arne; Stene, Guro Birgitte; Thorsen, Lene; Balstad, Trude Rakel; Solheim, Tora Skeidsvoll; Pripp, Are Hugo; Oldervoll, Line Merethe (Peer reviewed; Journal article, 2020)

  The aim of this meta-analysis was to examine the effects of nutritional and physical exercise interventions and interventions combining these interventions during radiotherapy treatment for patients with head and neck ...

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