• Association of treatment procedures and resilience to symptom load three-years later in a clinical sample of adolescent psychiatric patients 

  Gårdvik, Kari Skulstad; Rygg, Marite; Torgersen, Terje; Wallander, Jan Lance; Lydersen, Stian; Indredavik, Marit Sæbø (Peer reviewed; Journal article, 2021)

  Background We aimed to examine symptom load in a clinical adolescent population at three-year follow-up and explore associations with standard care treatment procedures and resilience factors upon first presenting at Child ...

• Transfer of triptans into human breast milk and estimation of infant drug exposure through breastfeeding 

  Amundsen, Siri; Nordeng, Hedvig; Nordeng, Hedvig Marie Egeland; Fuskevåg, Ole Martin; Nordmo, Elisabet; Nordmo, Elisabet N; Sager, Georg; Spigset, Olav (Peer reviewed; Journal article, 2021)

  Clinical data on the transfer of triptans into human breast milk remain scarce. In a lactation study including 19 breastfeeding women with migraine, we examined the excretion of six different triptans into milk. Following ...

• Differentiation status of primary chronic myeloid leukemia cells affects sensitivity to BCR-ABL1 inhibitors 

  Pietarinen, Paavo O; Eide, Christopher A; Ayuda-Duran, Maria del Pilar; Potdar, Swapnil; Kuusanmäki, Heikki; Andersson, Emma I; Mpindi, John P; Pemovska, Tea; Kontro, Mika; Heckman, Caroline A.; Kallioniemi, Olli; Wennerberg, Krister; Hjorth-Hansen, Henrik; Druker, Brian J; Enserink, Jorrit; Tyner, Jeffrey W.; Mustjoki, Satu; Porkka, Kimmo (Peer reviewed; Journal article, 2017)

  Tyrosine kinase inhibitors (TKI) are the mainstay treatment of BCR-ABL1-positive leukemia and virtually all patients with chronic myeloid leukemia in chronic phase (CP CML) respond to TKI therapy. However, there is limited ...

• Proteome alterations associated with transformation of multiple myeloma to secondary plasma cell leukemia 

  Zatula, Alexey; Dikic, Aida; Mulder, Teska Celine; Sharma, Animesh; Vågbø, Cathrine Broberg; Sousa, Mirta; Waage, Anders; Slupphaug, Geir (Peer reviewed; Journal article, 2017)

  Plasma cell leukemia is a rare and aggressive plasma cell neoplasm that may either originate de novo (primary PCL) or by leukemic transformation of multiple myeloma (MM) to secondary PCL (sPCL). The prognosis of sPCL is ...

• Identification of metastasis-associated microRNAs in serum from rectal cancer patients 

  Mjelle, Robin; Sellæg, Kjersti; Sætrom, Pål; Thommesen, Liv; Sjursen, Wenche; Hofsli, Eva (Peer reviewed; Journal article, 2017)

  MicroRNAs (miRNAs) are promising prognostic and diagnostic biomarkers due to their high stability in blood. Here we investigate the expression of miRNAs and other noncoding (nc) RNAs in serum of rectal cancer patients. ...

• Diagnostic Accuracy in Subtyping Basal Cell Carcinoma by Clinical Diagnosis Compared with Punch Biopsy 

  Christensen, Eidi; Mjønes, Patricia; Grimstad, Øystein; Rørdam, Ole Martin; Foss, Olav A. (Peer reviewed; Journal article, 2016)

• Bruk av andre vanedannende legemidler blant opioidbrukere med langvarige smerter 

  Odsbu, Ingvild; Handal, Marte; Hjellvik, Vidar; Borchgrevink, Petter Chr.; Clausen, Thomas; Hamina, Aleksi; Lid, Torgeir Gilje; Nesvåg, Ragnar; Skurtveit, Svetlana (Peer reviewed; Journal article, 2021)

  Bakgrunn: Opioider for behandling av langvarige smerter kan forskrives på blå resept, men bør ikke brukes samtidig med andre vanedannende legemidler. Hensikt: Å undersøke bruk av opioider på blå resept i perioden 2009-2019, ...

• The evaluation of aortic stenosis, how the new guidelines are implemented across Europe: A survey by EACVI 

  Michalski, Blazej; Dweck, Mark R.; Marsan, Nina Ajmone; Cameli, Matteo; D'Andrea, Antonello; Carvalho, Ricardo Fontes; Holte, Espen; Podlesnikar, Tomaz; Manka, Robert; Haugaa, Kristina (Peer reviewed; Journal article, 2020)

  Aortic stenosis (AS) is the most prevalent valvular disease in developed countries, with a prevalence that is set to expand further with an ageing population. The most recent guidelines on valvular heart disease published ...

• Interaction between overweight and genotypes of HLA, TCF7L2, and FTO in relation to the risk of latent autoimmune diabetes in adults and type 2 diabetes 

  Hjort, Rebecka; Löfvenborg, Josefin E.; Ahlqvist, Emma; Alfredsson, Lars; Andersson, Tomas; Grill, Valdemar Erik Robert; Groop, Leif; Sørgjerd, Elin Pettersen; Tuomi, Tiinamaija; Åsvold, Bjørn Olav; Carlsson, Sofia (Peer reviewed; Journal article, 2019)

  Objective We investigated potential interactions between body mass index (BMI) and genotypes of human leukocyte antigen (HLA), TCF7L2-rs7903146, and FTO-rs9939609 in relation to the risk of latent autoimmune diabetes in ...

• Neurotoxic effects of mercury exposure in dental personnel 

  Bjørklund, Geir; Hilt, Bjørn; Dadar, Maryam; Lindh, U; Aaseth, Jan (Peer reviewed; Journal article, 2019)

  Numerous studies have reported neurobehavioural effects in dental personnel occupationally exposed to chronic low levels of mercury (Hg). Hg exposure from dental work may also induce various chronic conditions such as ...

• Levator ani muscle morphology and function in women with obstetric anal sphincter injury 

  Volløyhaug, Ingrid; Taithongchai, Annika; van Gruting, Isabelle; Sultan, Abdul; Thakar, Ranee (Peer reviewed; Journal article, 2019)

  Objectives To estimate the prevalence of, and explore the risk factors for, levator ani muscle (LAM) injury in women with clinically diagnosed obstetric anal sphincter injury (OASI). The secondary aim was to assess the ...

• Hysterotomy level at cesarean section and occurrence of large scar defects: a randomized single-blind trial 

  Vikhareva, Olga; Skott Rickle, G; Lavesson, T; Nedopekina, E; Brandell, K; Salvesen, Kjell Å (Peer reviewed; Journal article, 2019)

  Objective To study the association between the level of Cesarean hysterotomy and the presence of large uterine scar defects 6–9 months after delivery. Methods This was a two-center, randomized, single-blind trial of ...

• The Assistive Device Situation for ALS Patients in Norway 

  Rolland, Jenny Pernilla; Meisingset, Tore Wergeland; Myrberget, Mari-Anne (Peer reviewed; Journal article, 2021)

  Aims. There are limited analytical descriptions of the assistive device situation in Norway for patients with ALS and other motor neuron diseases. This study is aimed at investigating how patients, caregivers, and healthcare ...

• Boys and girls differ in symptoms and neurodevelopmental outcome after perinatal metabolic acidosis, a population-based study 

  Hafström, Maria; Salvesen, Øyvind; Kjellmer, Ingemar (Peer reviewed; Journal article, 2018)

  Aim To evaluate sex differences in infants born at term with metabolic acidosis with regard to perinatal health and symptomatology, and developmental outcome. Methods From a population-based cohort of infants born at ...

• A Compilation of Serum Concentrations of 12 Antipsychotic Drugs in a Therapeutic Drug Monitoring Setting 

  Jonsson, Anna K.; Spigset, Olav; Reis, Margareta (Peer reviewed; Journal article, 2019)

  Background: No comprehensive collection of routine therapeutic drug monitoring data for antipsychotic drugs has been published. Methods: In this compilation, data on 12 antipsychotics are presented. The drugs included ...

• microRNA-451a prevents activation of matrix metalloproteinases 2 and 9 in human cardiomyocytes during pathological stress stimulation. 

  Scrimgeour, Nathan Robert; Wrobel, Aleksandra Zofia; Pinho, Maria; Høydal, Morten (Peer reviewed; Journal article, 2019)

  Matrix metalloproteinases (MMP) are important for cardiac remodeling. Recently, microRNA (miR)-451a has been found to inhibit the expression of both MMP-2 and MMP-9 in human malignancies, but its role in cardiomyocytes has ...

• Exercise training for patients with type 2 diabetes and cardiovascular disease: What to pursue and how to do it. A Position Paper of the European Association of Preventive Cardiology (EAPC) 

  Kemps, Hareld; Kränkel, Nicolle; Dörr, Marcus; Moholdt, Trine; Wilhelm, Matthias; Paneni, Francesco; Serratosa, Luis; Solberg, Erik Ekker; Hansen, Dominique; Halle, Martin; Guazzi, Marco (Peer reviewed; Journal article, 2019)

  Patients with type 2 diabetes mellitus suffer from dysregulation of a plethora of cardiovascular and metabolic functions, including dysglycaemia, dyslipidaemia, arterial hypertension, obesity and a reduced cardiorespiratory ...

• 3D ultrasound-guided resection of low-grade gliomas: principles and clinical examples 

  Unsgård, Geirmund; Lindseth, Frank (Journal article, 2019)

  3D ultrasound (US) is a convenient tool for guiding the resection of low-grade gliomas, seemingly without deterioration in patients’ quality of life. This article offers an update of the intraoperative workflow and the ...

• The effect of smoking intensity on all-cause and cause-specific mortality-a Mendelian randomization analysis. 

  Vie, Gunnhild Åberge; Wootton, Robyn E; Bjørngaard, Johan Håkon; Åsvold, Bjørn Olav; Taylor, AE; Gabrielsen, Maiken Elvestad; Davey, George Smith; Romundstad, Pål Richard; Munafo, Marcus R (Peer reviewed; Journal article, 2019)

  Background Smoking is an important cause of mortality and recent studies have suggested that even low-intensity smoking might be associated with increased mortality. Still, smoking is associated with lower socio-economic ...

• Correlation Between Digital and Manual Determinations of Ki-67/MIB-1 Proliferative Indices in Human Meningiomas 

  Pham, Duc-Tien; Skaland, Ivar; Winther, Theo L.; Salvesen, Øyvind; Torp, Sverre Helge (Peer reviewed; Journal article, 2019)

  Objective. Proliferative activity in tumor tissues is assessed as the percentage of Ki-67/MIB-1-positive cells, or the proliferative index (PI). The PI is routinely assessed manually. However, the subjectivity of manual ...

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