• Cancer patients have a reduced likelihood of dying in hospital with advance care planning in primary health care and a summarizing palliative plan: a prospective controlled non-randomized intervention trial 

  Driller, Bardo; Talseth-Palmer, Bente Anita; Hole, Torstein Laurits; Strømskag, Kjell Erik; Brenne, Anne Tove (Journal article; Peer reviewed, 2024)

  Background: Advance care planning (ACP) allows patients to define their goals and preferences. Spending more time at home and less time in the hospital, along with avoiding death in the hospital, are often considered ...

• Changes in the Gastrointestinal Microbiota Induced by Proton Pump Inhibitors—A Review of Findings from Experimental Trials 

  Fossmark, Reidar; Olaisen, Maya (Journal article; Peer reviewed, 2024)

  The use of proton pump inhibitors (PPIs) has increased considerably in many Western countries, and there is concern that numerous conditions and diseases associated with PPI use may be adverse events. The main function of ...

• Associations of Urine Epidermal Growth Factor With Kidney and Cardiovascular Outcomes in Individuals With CKD in SPRINT 

  Postalcioglu, Merve; Katz, Ronit; Ascher, Simon B.; Hall, Trenton; Garimella, Pranav S.; Hallan, Stein Ivar; Ix, Joachim H.; Shlipak, Michael G. (Journal article; Peer reviewed, 2024)

  Introduction: Urine epidermal growth factor (uEGF) has been found to be inversely associated with kidney function loss, whereas its associations with cardiovascular disease (CVD) and mortality have not been studied. Methods: ...

• Neurodevelopmental outcome at two years of age and predictive value of General Movement Assessment in infants exposed to alcohol and/or drugs during pregnancy: a prospective cohort study 

  Fjørtoft, Toril Synnøve Larsson; Brandal, Merethe; Adde, Lars; Osland, Siril; Rygh, Hilde; Ustad, Tordis; Evensen, Kari Anne Indredavik (Journal article; Peer reviewed, 2024)

  Background: Exposure to alcohol and/or other addictive drugs in pregnancy is a documented risk factor for neurological impairment. We aimed to assess neurodevelopmental outcome at two years of age in infants exposed to ...

• Navigating weight, risk and lifestyle conversations in maternity care: a qualitative study among pregnant women with obesity 

  Sandsæter, Heidi Linn; Tetlie Eik-Nes, Trine; Getz, Linn Okkenhaug; Magnussen, Elisabeth Balstad; Rich-Edwards, Janet W.; Horn, Julie (Journal article; Peer reviewed, 2024)

  Background: Pregnant women with obesity face heightened focus on weight during pregnancy due to greater risk of medical complications. Closer follow-up in maternety care may contribute to reduce risk and promote health in ...

• Systematic review and meta-analysis of pregnancy outcomes in women with polycystic ovary syndrome 

  Bahri Khomami, Mahnaz; Shorakae, Soulmaz; Hashemi, Somayeh; Harrison, Cheryce L.; Piltonen, Terhi T.; Romualdi, Daniela; Tay, Chau Thien; Teede, Helena J.; Vanky, Eszter Ilona; Mousa, Aya (Journal article; Peer reviewed, 2024)

  Screening for polycystic ovary syndrome (PCOS) in antenatal care is inadequate, largely owing to the lack of clarity around whether PCOS is an independent risk factor for pregnancy complications. This systematic review and ...

• Association between parental psychiatric disorders and risk of offspring autism spectrum disorder: a Swedish and Finnish population-based cohort study 

  Yin, Weiyao; Pulakka, Anna; Reichenberg, Abraham; Kolevzon, Alexander; Ludvigsson, Jonas F.; Risnes, Kari; Lahti-Pulkkinen, Marius; Persson, Martina; Silverman, Michael E.; Åden, Ulrika; Kajantie, Eero Olavi; Sandin, Sven (Journal article; Peer reviewed, 2024)

  Background: Roughly more than one in six adults worldwide suffer from psychiatric conditions. Sporadic studies have associated parental psychiatric disorders with autism spectrum disorder in offspring. Comprehensively ...

• Stress responses in surgical trainees during simulation-based training courses in laparoscopy 

  Tjønnås, Maria Suong; Muller, Sébastien; Våpenstad, Cecilie; Tjønnås, Johannes; Ose, Solveig Osborg; Das, Anita; Sandsund, Mariann (Journal article; Peer reviewed, 2024)

  Background: Simulation-based training courses in laparoscopy have become a fundamental part of surgical training programs. Surgical skills in laparoscopy are challenging to master, and training in these skills induces ...

• Elevated High Sensitivity C Reactive Protein and Risk of Abdominal Aortic Aneurysm: A Prospective Population Based Study in The Norwegian HUNT Study 

  Håland, Aslak Bryne; Mattsson, Erney; Videm, Vibeke; Albrektsen, Grethe; Nyrønning, Linn Åldstedt (Journal article; Peer reviewed, 2025)

  Objective: Inflammation seems to be crucial in the pathogenesis of abdominal aortic aneurysm (AAA). Previous research links inflammatory biomarkers, such as high sensitivity C reactive protein (hs-CRP), to AAA. Few studies, ...

• Type 1 Autoimmune Pancreatitis in Europe: Clinical Profile and Response to Treatment 

  Overbeek, Kasper A.; Poulsen, Jakob L.; Lanzillotta, Marco; Holmquist, Olof Dan Sebastian; Macinga, Peter; Demirci, A. Fatih; Sindhunata, Daniko P.; Backhus, Johanna; Algül, Hana; Buijs, Jorie; Levy, Philippe; Kiriukova, Mariia; Goni, Elisabetta; Hollenbach, Marcus; Miksch, Rainer C.; Kunovsky, Lumir; Vujasinovic, Miroslav; Nikolic, Sara; Dickerson, Luke; Hirth, Michael; Neurath, Markus F.; Zumblick, Malte; Vila, Josephine; Jalal, Mustafa; Beyer, Georg; Frost, Fabian; Carrara, Silvia; Kala, Zdenek; Jabandziev, Petr; Sisman, Gurhan; Akyuz, Filiz; Capurso, Gabriele; Falconi, Massimo; Arlt, Alexander; Vleggaar, Frank P.; Barresi, Luca; Greenhalf, Bill; Czakó, László; Hegyi, Peter; Hopper, Andrew; Nayar, Manu K.; Gress, Thomas M.; Vitali, Francesco; Schneider, Alexander; Halloran, Chris M.; Trna, Jan; Okhlobystin, Alexey V.; Dagna, Lorenzo; Cahen, Djuna L.; Bordin, Dmitry; Rebours, Vinciane; Mayerle, Julia; Kahraman, Alisan; Rasch, Sebastian; Culver, Emma; Kleger, Alexander; Martínez-Moneo, Emma; Røkke, Ola; Hucl, Tomas; Olesen, Søren S.; Bruno, Marco J.; Della-Torre, Emanuel; Beuers, Ulrich; Löhr, J.-Matthias; Rosendahl, Jonas (Peer reviewed; Journal article, 2024)

  BACKGROUND & AIMS: Autoimmune pancreatitis (AIP) is an immune-mediated disease of the pancreas with distinct pathophysiology and manifestations. Our aims were to characterize type 1 AIP in a large pan-European cohort and ...

• “Gastrointestinal Quality of Life After Congenital Duodenal Obstruction Repair: A Nationwide Long-term Follow-up Study” 

  Treider, Martin; Røkkum, Henrik; Sæter, Thorstein; Bjørnland, Kristin (Peer reviewed; Journal article, 2024)

  Background Congenital duodenal obstruction (CDO) is one of the most common gastrointestinal congenital anomalies. Still, patient-reported long-term results are limited. The aims of this study were to evaluate the long-term ...

• Enteroaggregative Escherichia coli in mid-Norway: A prospective, case control study 

  Haugan, Ingvild; Husby, Marit Gudrun; Skjøtskift, Bjørg; Mostue, Dorothea Aamnes; Brun, Andreas; Olsen, Lene Christin; Simpson, Melanie Rae; Lange, Heidi; Afset, Jan Egil (Peer reviewed; Journal article, 2024)

  Background The use of molecular methods has led to increased detection of Enteroaggregative Escherichia coli (EAEC) in faecal samples. Studies have yielded conflicting results regarding the clinical relevance of this ...

• Pelvic floor status in opera singers. a pilot study using transperineal ultrasound 

  Volløyhaug, Ingrid; Semmingsen, Tuva Haugen; Laukkanen, Anne-Maria; Karoliussen, Clara; Bjørkøy, Kåre (Peer reviewed; Journal article, 2024)

  Background: Control of pelvic floor muscles (PFM) is emphasized as important to obtain functional breath support in opera singing, but there is not much research that proves PFM function as part of breath support in classical ...

• Development of a predictive model for patients with bone metastases referred to palliative radiotherapy: Secondary analysis of a multicenter study (the PRAIS trial) 

  Rossi, Romina; Medici, Federica; Habberstad, Ragnhild Hansdatter; Klepstad, Pål; Cilla, Savino; Dall'Agata, Monia; Kaasa, Stein; Caraceni, Augusto Tomasso Giovanni; Morganti, Alessio Giuseppe; Maltoni, Marco (Journal article; Peer reviewed, 2024)

  Background: The decision to administer palliative radiotherapy (RT) to patients with bone metastases (BMs), as well as the selection of treatment protocols (dose, fractionation), requires an accurate assessment of survival ...

• Progression-free survival versus post-progression survival and overall survival in WHO grade 2 gliomas 

  Sagberg, Lisa Millgård; Salvesen, Øyvind Olav; Jakola, Asgeir Store; Thurin, Erik; De Dios, Eddie; Nawabi, Noah L.A; Kilgallon, John L.; Bernstock, Joshua D.; Kavouridis, Vasileios; Smith, Timothy R.; Solheim, Ole Skeidsvoll (Journal article; Peer reviewed, 2024)

  Background and purpose: Progression-free survival (PFS) remains to be validated as an outcome measure for diffuse WHO grade 2 gliomas, and knowledge about the relationships between PFS, post-progression survival (PPS), and ...

• Single cell and spatial transcriptomics highlight the interaction of club-like cells with immunosuppressive myeloid cells in prostate cancer 

  Kiviaho, Antti; Eerola, Sini K.; Kallio, Heini M.L.; Andersen, Maria K.; Hoikka, Miina; Salonen, Iida; Spotbeen, Xander; Giesen, Alexander; Parker, Charles T.A.; Taavitsainen, Sinja; Hantula, Olli; Marttinen, Mikael; Harmelo, Ismael; Ismail, Mazlina; Midtbust, Elise; Wess, Maximilian; Devlies, Wout; Sharma, Abhibhav; Krossa, Sebastian; Häkkinen, Tomi; Afyounian, Ebrahim; Vandereyken, Katy; Kint, Sam; Kesseli, Juha; Tolonen, Teemu; Tammela, Teuvo L.J.; Viset, Trond; Størkersen, Øystein; Giskeødegård, Guro F.; Rye, Morten Beck; Murtola, Teemu; Erickson, Andrew; Latonen, Leena; Bova, Steven G.; Mills, Ian Geoffrey; Joniau, Steven; Swinnen, Johannes V.; Voet, Thierry; Mirtti, Tuomas; Attard, Gerhardt; Claessens, Frank; Visakorpi, Tapio; Rautajoki, Kirsi J.; Tessem, May-Britt; Urbanucci, Alfonso; Nykter, Matti; Tiihonen, Aliisa M. (Journal article; Peer reviewed, 2024)

  Prostate cancer treatment resistance is a significant challenge facing the field. Genomic and transcriptomic profiling have partially elucidated the mechanisms through which cancer cells escape treatment, but their relation ...

• Single-cell multiomics analysis of chronic myeloid leukemia links cellular heterogeneity to therapy response 

  Warfvinge, Rebecca; Geironson Ulfsson, Linda; Dhapola, Parashar; Safi, Fatemeh; Sommarin, Mikael; Soneji, Shamit; Hjorth-Hansen, Henrik; Mustjoki, Satu; Richter, Johan; Thakur, Ram Krishna; Karlsson, Göran (Journal article; Peer reviewed, 2024)

  The advent of tyrosine kinase inhibitors (TKIs) as treatment of chronic myeloid leukemia (CML) is a paradigm in molecularly targeted cancer therapy. Nonetheless, TKI-insensitive leukemia stem cells (LSCs) persist in most ...

• Systematic review and meta-analysis of birth outcomes in women with polycystic ovary syndrome 

  Bahri Khomami, Mahnaz; Hashemi, Somayeh; Shorakae, Soulmaz; Harrison, Cheryce L.; Piltonen, Terhi T.; Romualdi, Daniela; Tay, Chau Thien; Mousa, Aya; Vanky, Eszter Ilona; Teede, Helena J. (Journal article; Peer reviewed, 2024)

  It is unclear whether polycystic ovary syndrome (PCOS) is an independent risk factor for adverse birth outcomes in the offspring of affected women. Here, we investigate the association of PCOS with birth outcomes in the ...

• X-bundet hypofosfatemi 

  Wang, Qidi; Akdeniz, Cennet; Heck, Ansgar; Bjørk, Mai Britt; Theisen, Ole Rasmus; Eggesbø, Heidi Beate; Krüger, Tormod Bjartveit; Reseland, Janne Elin; Pihlstrøm, Hege Kampen; Åsvold, Bjørn Olav; Grimnes, Guri; Grytaas, Marianne Aardal; Rafaelsen, Silje Hjorth; Thorsby, Per Medbøe; Wekre, Lena Lande; Finnes, Trine Elisabeth (Journal article; Peer reviewed, 2025)

  X-bundet hypofosfatemi er en sjelden genetisk sykdom som medfører fosfattap i nyrene, redusert mineralisering av tenner og skjelett, deformerte knokler og begrenset mobilitet. Dette har betydelige konsekvenser for helse ...

• Effect of tocilizumab on endothelial and platelet-derived CXC-chemokines and their association with inflammation and myocardial injury in STEMI patients undergoing primary PCI 

  Woxholt, Sindre; Ueland, Thor; Aukrust, Pål; Anstensrud, Anne Kristine; Broch, Kaspar; Tøllefsen, Ingvild Maria; Seljeflot, Ingebjørg; Halvorsen, Bente; Dahl, Tuva Børresdatter; Huse, Camilla; Andersen, Geir Øystein; Gullestad, Lars; Wiseth, Rune; Damås, Jan Kristian; Kleveland, Ola (Journal article; Peer reviewed, 2025)

  Background: Tocilizumab improves myocardial salvage in ST-elevation myocardial infarction (STEMI) patients when administered before percutaneous coronary intervention (PCI). The mechanisms underlying ischemia-reperfusion ...

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