• Desflurane consumption with automated vapour control systems in two different anaesthesia machines. A randomized controlled study 

  Mostad, Dagmar; Klepstad, Pål; Follestad, Turid; Pleym, Hilde (Peer reviewed; Journal article, 2021)

  Background: In general anaesthesia practice a fresh gas flow (FGF) of ≥0.5 L/min is usually applied. Automated gas delivery devices are developed to reduce volatile anaesthetic consumption by limiting gas flow. This study ...

• Post-concussion symptoms three months after mild-to-moderate TBI: characteristics of sick-listed patients referred to specialized treatment and consequences of intracranial injury 

  Fure, Silje Christine Reistad; Howe, Emilie; Spjelkavik, Øystein; Røe, Cecilie; Rike, Per-Ola; Olsen, Alexander; Ponsford, Jennie; Andelic, Nada; Løvstad, Marianne (Journal article; Peer reviewed, 2021)

  Objective: To present pre-injury, injury-related, work-related and post-injury characteristics, and to compare patients with and without traumatic intracranial abnormalities, in a treatment-seeking sample with persistent ...

• Pharmacokinetics of Intraperitoneally Delivered Glucagon in Pigs: A Hypothesis of First Pass Metabolism 

  Teigen, Ingrid Anna; Åm, Marte Kierulf; Carlsen, Sven Magnus; Christiansen, Sverre Christian (Peer reviewed; Journal article, 2021)

  Background and Objective Artificial pancreases administering low-dose glucagon in addition to insulin have the scope to improve glucose control in patients with diabetes mellitus type 1. If such a device were to deliver ...

• Experimental sleep restriction increases latency jitter in pain elicited cortical responses 

  Hansen, Johannes Orvin; Omland, Petter Moe; Nilsen, Kristian Bernhard; Sand, Trond; Matre, Dagfinn (Peer reviewed; Journal article, 2021)

  Objective Previous studies have shown increased pain scores to painful stimulation after experimental sleep restriction, but reduced or unchanged magnitude of the event related potentials (ERPs) when averaged in the ...

• Can functional walk tests add value to the prediction of cardiorespiratory fitness after stroke? A prospective cohort study 

  Gunnes, Mari; Aksetøy, Inger-Lise Aamot; Follestad, Turid; Indredavik, Bent; Askim, Torunn (Journal article; Peer reviewed, 2021)

  Background Cardiorespiratory fitness is often impaired following stroke, and peak oxygen consumption (VO2peak) is an important prognostic value of all-cause mortality. The primary objective was to investigate whether ...

• A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease 

  Wightman, Douglas P.; Jansen, Iris E.; Savage, Jeanne E.; Shadrin, Alexey; Bahrami, Shahram; Holland, Dominic; Rongve, Arvid; Børte, Sigrid; Winsvold, Bendik K S; Drange, Ole Kristian; Martinsen, Amy E.; Skogholt, Anne Heidi; Willer, Cristen; Bråthen, Geir; Bosnes, Ingunn; Nielsen, Jonas Bille; Fritsche, Lars; Thomas, Laurent; Pedersen, Linda Margareth; Gabrielsen, Maiken Elvestad; Johnsen, Marianne Bakke; Meisingset, Tore Wergeland; Zhou, Wei; Proitsi, Petroula; Hodges, Angela; Dobson, Richard; Velayudhan, Latha; Sealock, Julia; Davis, Lea K.; Pedersen, Nancy L.; Reynolds, Chandra A.; Karlsson, Ida K.; Magnusson, Sigurdur; Stefansson, Hreinn; Thordardottir, Steinunn; Jónsson, Pálmi V.; Snædal, Jon; Zettergren, Anna; Skoog, Ingmar; Kern, Silke; Waern, Margda; Zetterberg, Henrik; Blennow, Kaj; Stordal, Eystein; Hveem, Kristian; Zwart, John Anker Henrik; Athanasiu, Lavinia; Selnes, Per; Saltvedt, Ingvild; Sando, Sigrid Botne; Ulstein, Ingun; Djurovic, Srdjan; Fladby, Tormod; Aarsland, Dag; Selbæk, Geir; Ripke, Stephan; Stefánsson, Kári; Andreassen, Ole; Posthuma, Danielle (Journal article; Peer reviewed, 2021)

  Late-onset Alzheimer’s disease is a prevalent age-related polygenic disease that accounts for 50–70% of dementia cases. Currently, only a fraction of the genetic variants underlying Alzheimer’s disease have been identified. ...

• Effects of intermittent negative pressure treatment on circulating vascular biomarkers in patients with intermittent claudication 

  Hoel, Henrik; Pettersen, Erik Mulder; Høiseth, Lars Øivind; Mathiesen, Iacob; Seternes, Arne; Seljeflot, Ingebjørg; Hisdal, Jonny (Journal article; Peer reviewed, 2021)

  The aim of this study was to investigate the effects of lower extremity intermittent negative pressure (INP) treatment for 1 hour twice daily for 12 weeks, on circulating vascular biomarkers in patients with intermittent ...

• DSM-5 and ICD-11 criteria for bipolar disorder: Implications for the prevalence of bipolar disorder and validity of the diagnosis – A narrative review from the ECNP bipolar disorders network 

  Kessing, Lars Vedel; Gonzalez-Pinto, Ana; Fagiolini, Andrea; Bechdolf, Andreas; Reif, Andreas; Yildiz, Ayşegül; Etain, Bruno; Henry, Chantal; Severus, Emanuel; Reininghaus, Eva Z.; Morken, Gunnar; Goodwin, Guy M.; Scott, Jan; Geddes, John R.; Rietschel, Marcella; Landén, Mikael; Manchia, Mirko; Bauer, Michael; Martinez-Cengotitabengoa, Monica; Andreassen, Ole Andreas; Ritter, Philipp; Kupka, Ralph; Licht, Rasmus W.; Nielsen, René E.; Schulze, Thomas G.; Hajek, Tomas; Lagerberg, Trine Vik; Bergink, Veerle; Vieta, Eduard (Peer reviewed; Journal article, 2021)

  This narrative review summarizes and discusses the implications of the Diagnostic and Statistical Manual of Mental Disorders (DSM)-5 and the upcoming International Classification of Diseases (ICD)-11 classification systems ...

• Cementless unicompartmental knee arthroplasty results in higher pain levels compared to the cemented technique: a prospective register study 

  Gifstad, Tone; Nordskar, Jørgen Jebens; Egeberg, Tarjei; Wik, Tina Strømdal; Winther, Siri Bjørgen (Peer reviewed; Journal article, 2021)

  Purpose In recent years, the preferred fxation method for unicompartmental knee arthroplasty (UKA) has changed from cemented to cementless. The aim of this study was to compare patient-reported outcome measures (PROMs) ...

• Prediction of outcome from MRI and general movements assessment after hypoxic-ischaemic encephalopathy in low-income and middle-income countries: data from a randomised controlled trial 

  Aker, Karoline; Thomas, Niranjan; Adde, Lars; Koshy, Beena; Martinez-Biarge, Miriam; Nakken, Ingeborg Elise; Padankatti, Caroline; Støen, Ragnhild (Peer reviewed; Journal article, 2021)

  Objective To evaluate the accuracy of neonatal MRI and general movements assessment (GMA) in predicting neurodevelopmental outcomes in infants with hypoxic-ischaemic encephalopathy (HIE). Design Secondary analyses of a ...

• Are We Transitioning Toward Person-centered Practice on Self-management Support? An Explorative Case Study Among Rheumatology Outpatient Clinic Nurses in Norway 

  Fischer, Heike; Grønning, Kjersti (Peer reviewed; Journal article, 2021)

  Introduction: There are only a few studies investigating nurses’ views on self-management in the care of patients with rheumatic diseases. Objective: The aim of this study is to explore how Norwegian rheumatology outpatient ...

• Patient derived colonoids as drug testing platforms-Critical importance of oxygen concentration 

  Skovdahl, Helene Kolstad; Gopalakrishnan, Shreya; Svendsen, Tarjei Dahl; Granlund, Atle van Beelen; Bakke, Ingunn; Ginbot, Zekarias; Thorsvik, Silje; Flatberg, Arnar; Sporsheim, Bjørnar; Ostrop, Jenny; Mollnes, Tom Eirik; Sandvik, Arne Kristian; Bruland, Torunn (Peer reviewed; Journal article, 2021)

  Treatment of inflammatory bowel disease (IBD) is challenging, with a series of available drugs each helping only a fraction of patients. Patients may face time-consuming drug trials while the disease is active, thus there ...

• Postponed Withholding: Balanced Decision-Making at the Margins of Viability 

  Syltern, Janicke; Ursin, Lars Øystein; Solberg, Berge; Støen, Ragnhild (Peer reviewed; Journal article, 2021)

  Advances in neonatology have led to improved survival for periviable infants. Immaturity still carries a high risk of short- and long-term harms, and uncertainty turns provision of life support into an ethical dilemma. ...

• Evaluation of the EQ-5D-3L and 5L versions in low back pain patients 

  Garratt, Andrew; Furunes, Håvard; Hellum, Christian; Solberg, Tore; Brox, Jens Ivar; Storheim, Kjersti; Johnsen, Lars Gunnar (Peer reviewed; Journal article, 2021)

  Background The EuroQol EQ-5D is one of the most widely researched and applied patient-reported outcome measures worldwide. The original EQ-5D-3L and more recent EQ-5D-5L include three and five response categories respectively. ...

• Can a Dinosaur Think? Implementation of Artificial Intelligence in Extracorporeal Shock Wave Lithotripsy 

  Muller, Sebastien; Abildsnes, Håkon; Østvik, Andreas; Kragset, Oda; Gangås, Inger Sofie Hovd; Birke, Harriet; Langø, Thomas; Arum, Carl-Jørgen (Peer reviewed; Journal article, 2021)

  Background: Extracorporeal shock wave lithotripsy (ESWL) of kidney stones is losing ground to more expensive and invasive endoscopic treatments. Objective: This proof-of-concept project was initiated to develop artificial ...

• Inflammatory markers are altered in severe mental disorders independent of comorbid cardiometabolic disease risk factors 

  Mørch, Ragni Helene; Dieset, Ingrid; Færden, Ann; Reponen, Elina Johanna; Hope, Sigrun; Hoseth, Eva Zsuzsanna; Gardsjord, Erlend Strand; Aas, Monica; Iversen, Trude; Joa, Inge; Morken, Gunnar; Agartz, Ingrid; Melle, Ingrid; Aukrust, Pål; Djurovic, Srdjan; Ueland, Thor; Andreassen, Ole Andreas (Peer reviewed; Journal article, 2019)

  Background. Inflammation and immune activation have been implicated in the pathogenesis of severe mental disorders and cardiovascular disease (CVD). Despite high level of comorbidity, many studies of the immune system in ...

• Transcriptomic Profiling of Collagenous Colitis Identifies Hallmarks of Nondestructive Inflammatory Bowel Disease 

  Escudero-hernandez, Celia; Granlund, Atle van Beelen; Bruland, Torunn; Sandvik, Arne Kristian; Koch, Stefan; Østvik, Ann Elisabet; Munch, Andreas (Peer reviewed; Journal article, 2021)

  Background and aims: The pathophysiology of the inflammatory bowel disease collagenous colitis (CC) is poorly described. Our aim was to use RNA sequencing of mucosal samples from patients with active CC, CC in remission, ...

• Timing of severe toxicity from chemotherapy in patients with lung cancer 

  Sjøgren, Kristina; Jacobsen, Kristian Aalberg; Grønberg, Bjørn Henning; Halvorsen, Tarje Onsøien (Journal article; Peer reviewed, 2020)

  Background/Aim: The aim of this study was to investigate the timing of severe toxicity in lung cancer patients receiving chemotherapy. Patients and Methods: Patients with advanced non-small cell lung cancer or limited ...

• Alendronate and omeprazole in combination reduce angiogenic and growth signals from osteoblasts 

  Kruger, Tormod Bjartveit; Herlofson, Bente Brokstad; Lian, Aina-Mari; Syversen, Unni; Reseland, Janne Elin (Peer reviewed; Journal article, 2021)

  Objective: Due to gastrointestinal side effects of oral bisphosphonates (BPs), proton pump inhibitors (PPIs) are often prescribed. PPIs may enhance the risk of osteonecrosis of the jaw, a rare side effect of BPs. Therefore, ...

• Association between habitual sleep duration/quality and appetite markers in individuals with obesity 

  Nymo, Siren; Kleppe, Malin M.; Coutinho, Silvia; Rehfeld, Jens F.; Kulseng, Bård Eirik; Martins, Catia (Peer reviewed; Journal article, 2021)

  Study Objectives: To assess if habitual sleep duration/quality was associated with appetite in individuals with obesity, and if the association was modulated by sex. Methods: Sleep duration/quality was measured with ...

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