• Is disrupted sleep a risk factor for Alzheimer's disease? Evidence from a two-sample Mendelian randomization analysis 

  Anderson, Emma L.; Richmond, Rebecca C.; Jones, Samuel E.; Hemani, Gibran; Wade, Kaitlin H; Dashti, Hassan S.; Lane, Jaqueline; Wang, Heming; Saxena, Richa; Brumpton, Ben Michael; Korologou-Linden, Roxanna; Nielsen, Jonas Bille; Åsvold, Bjørn Olav; Abecasis, Goncalo; Coulthard, Elizabeth; Kyle, Simon D.; Beaumont, Robin N.; Tyrell, Jessica; Frayling, Timothy M; Munafo, Marcus R; Wood, Andrew R; Ben-Shlomo, Yoav; Howe, Laura D; Lawlor, Deborah A.; Weedon, Michael N; Smith, George Davey (Peer reviewed; Journal article, 2020)

  Background It is established that Alzheimer’s disease (AD) patients experience sleep disruption. However, it remains unknown whether disruption in the quantity, quality or timing of sleep is a risk factor for the onset ...

• Associations between post-stroke motor and cognitive function: a cross-sectional study 

  Einstad, Marte Stine; Saltvedt, Ingvild; Lydersen, Stian; Ursin, Marie Helene; Munthe-Kaas, Ragnhild; Ihle-Hansen, Hege; Askim, Torunn; Beyer, Mona K.; Næss, Halvor; Seljeseth, Yngve Müller; Ellekjær, Hanne; Thingstad, Pernille (Peer reviewed; Journal article, 2021)

  Background Motor and cognitive impairments are frequently observed following stroke, but are often managed as distinct entities, and there is little evidence regarding how they are related. The aim of this study was to ...

• Norwegian obstetricians' experiences of the use of ultrasound in pregnancy management. A qualitative study 

  Edvardsson, Kristina; Åhman, Annika; Fagerli, Tove Anita; Darj, Elisabeth; Holmlund, Sofia; Small, Rhonda; Mogren, Ingrid (Peer reviewed; Journal article, 2017)

  Objective To explore obstetricians’ experiences and views of the use of obstetric ultrasound in clinical management of pregnancy. Methods A qualitative interview study was undertaken in 2015 with obstetricians (N = 20) ...

• A validity study of the rapid emergency Triage and treatment system for children 

  Ødegård, Siv Steinsmo; Tran, Thuy; Næss-Pleym, Lars E.; Risnes, Kari; Døllner, Henrik (Peer reviewed; Journal article, 2021)

  Background: The Scandinavian Rapid Emergency Triage and Treatment System-pediatric (RETTS-p) is a reliable triage system that includes both assessment of vital parameters and a systematic approach to history and symptoms. ...

• Long-term motor outcomes of very preterm and/or very low birth weight individuals without cerebral palsy: A review of the current evidence 

  Evensen, Kari Anne Indredavik; Ustad, Tordis; Tikanmäki, Marjaana; Haaramo, Peija; Kajantie, Eero Olavi (Peer reviewed; Journal article, 2020)

  We reviewed literature on long-term motor outcomes of individuals aged five years or older born very preterm (VP: ≤32 weeks of gestation) or with very low birth weight (VLBW: ≤1500g), without cerebral palsy (CP). PubMed ...

• Rutinemessig kartlegging av fødselsdepresjon setter psykisk helse på dagsordenen 

  Langvik, Eva; Håberg, Cathrine Hystad; Storholt, Helene Høve (Journal article; Peer reviewed, 2020)

• Quality measurement in physician-staffed emergency medical services: a systematic literature review 

  Haugland, Helge Nystad; Uleberg, Oddvar; Klepstad, Pål; Krüger, Andreas; Rehn, Marius (Peer reviewed; Journal article, 2018)

  Purpose Quality measurement of physician-staffed emergency medical services (P-EMS) is necessary to improve service quality. Knowledge and consensus on this topic are scarce, making quality measurement of P-EMS a high-priority ...

• Modeling the diffusion-weighted imaging signal for breast lesions in the b = 200 to 3000 s/mm 2 range: quality of fit and classification accuracy for different representations 

  Vidic, Igor; Egnell, Liv Elisabet; Jerome, Neil Peter; White, Nathan; Karunamuni, Roshan; Rakow-Penner, Rebecca; Dale, Anders M.; Bathen, Tone Frost; Goa, Pål Erik (Peer reviewed; Journal article, 2020)

  Purpose To evaluate different non‐Gaussian representations for the diffusion‐weighted imaging (DWI) signal in the b‐value range 200 to 3000 s/mm2 in benign and malignant breast lesions. Methods Forty‐three patients ...

• The Mammalian Cap-Specific m⁶Am RNA Methyltransferase PCIF1 Regulates Transcript Levels in Mouse Tissues 

  Pandey, Radha Raman; Delfino, Elena; Homolka, David; Roithova, Adriana; Chen, Kuan-Ming; Li, Lingyun; Franco, Giulia; Vågbø, Cathrine Broberg; Taillebourg, Emmanuel; Fauvarque, Marie-Odile; Pillai, Ramesh S. (Peer reviewed; Journal article, 2020)

  The 5′ end of eukaryotic mRNAs is protected by the m7G-cap structure. The transcription start site nucleotide is ribose methylated (Nm) in many eukaryotes, whereas an adenosine at this position is further methylated at the ...

• Identification and Tracking of Antiviral Drug Combinations 

  Ianevski, Aleksandr; Yao, Rouan; Biza, Svetlana; Zusinaite, Eva; Mannik, Andres; Kivi, Gaily; Planken, Anu; Kurg, Kristiina; Tombak, Eva-Maria; Ustav, Mart Jr; Shtaida, Nastassia; Kulesskiy, Evgeny; Jo, Eunji; Yang, Jaewon; Lysvand, Hilde; Løseth, Kirsti; Oksenych, Valentyn; Aas, Per Arne; Tenson, Tanel; Vitkauskienė, Astra; Windisch, Marc P; Fenstad, Mona H.; Nordbø, Svein Arne; Ustav, Mart; Bjørås, Magnar; Kainov, Denis (Peer reviewed; Journal article, 2020)

  Combination therapies have become a standard for the treatment for HIV and hepatitis C virus (HCV) infections. They are advantageous over monotherapies due to better efficacy, reduced toxicity, as well as the ability to ...

• Long-Term Outcomes of Genetic Parkinson's Disease 

  Aasly, Jan (Journal article, 2020)

  Parkinson's disease (PD) is a progressive neurodegenerative disorder that affects 1-2% of people by the age of 70 years. Age is the most important risk factor, and most cases are sporadic without any known environmental ...

• GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer 

  Zhou, Wei; Brumpton, Ben Michael; Kabil, Omer; Gudmundsson, Julius; Thorleifsson, Gudmar; Weinstock, Joshua; Zawistowski, Matthew; Nielsen, Jonas Bille; Chaker, Layal; Medici, Marco; Teumer, Alexander; Naitza, Silvia; Sanna, Serena; Schultheiss, Ulla T.; Cappola, Anne R.; Karjalainen, Juha; Kurki, Mitja I.; Oneka, Morgan; Taylor, Peter; Fritsche, Lars; Graham, Sarah E.; Wolford, Brooke N.; Overton, William; Rasheed, Humaira; Bordal, Eirin Haug; Gabrielsen, Maiken Elvestad; Skogholt, Anne Heidi; Surakka, Ida; Davey Smith, George; Pandit, Anita; Roychowdhury, Tanmoy; Hornsby, Whitney; Jonasson, Jon G.; Senter, Leigha; Liyanarachchi, Sandya; Ringel, Matthew D.; Xu, Li; Kiemeney, Lambertus A.; He, Huiling; Netea-Maier, Romana; Mayordomo, Jose; Plantinga, Theo S.; Hrafnkelsson, Jon; Hjartarson, Hannes; Sturgis, Erich M.; Palotie, Aarno; Daly, Mark J.; Citterio, Cintia E.; Arvan, Peter; Brummett, Chad M.; Boehnke, Michael; de la Chapelle, Albert; Stefansson, Kari; Hveem, Kristian; Willer, Cristen J.; Åsvold, Bjørn Olav (Peer reviewed; Journal article, 2020)

  Thyroid stimulating hormone (TSH) is critical for normal development and metabolism. To better understand the genetic contribution to TSH levels, we conduct a GWAS meta-analysis at 22.4 million genetic markers in up to ...

• Twelve months effect of self-referral to inpatient treatment on patient activation, recovery, symptoms and functioning: A randomized controlled study 

  Moljord, Inger Elise Opheim; Lara Cabrera, Mariela Loreto; Salvesen, Øyvind; Rise, Marit By; Bjørgen, Dagfinn; Antonsen, Dag Øivind; Olsø, Turid Møller; Evensen, Gretha Helen; Gudde, Camilla Buch; Linaker, Olav Morten; Steinsbekk, Aslak; Eriksen, Lasse (Peer reviewed; Journal article, 2017)

  Objective To investigate the effect of having a contract for self-referral to inpatient treatment (SRIT) in patients with severe mental disorders. Methods A randomized controlled trial with 53 adult patients; 26 ...

• Mitochondrial Mechanisms of LRRK2 G2019S Penetrance 

  Delcambre, Sylvie; Ghelfi, Jenny; Ouzren, Nazzima; Grandmougin, Lea; Delbrouck, Catherine; Seibler, Philip; Wasner, Kobi; Aasly, Jan; Klein, Christine; Trinh, Joanne; Pereira, Sandro L; Grünewald, Anne (Peer reviewed; Journal article, 2020)

  Several mutations in leucine-rich repeat kinase-2 (LRRK2) have been associated with Parkinson's disease (PD). The most common substitution, G2019S, interferes with LRRK2 kinase activity, which is regulated by autophosphorylation. ...

• The water channel aquaporin 8 is a critical regulator of intestinal fluid homeostasis in collagenous colitis 

  Escudero-Hernandez, Celia; Münch, Andreas; Østvik, Ann Elisabet; Granlund, Atle van Beelen; Koch, Stefan (Peer reviewed; Journal article, 2020)

  Background and Aims: Diarrhoea is a common, debilitating symptom of gastrointestinal disorders. Pathomechanisms probably involve defects in trans-epithelial water transport, but the role of aquaporin [AQP] family water ...

• Use of references in responses from Scandinavian drug information centres 

  Schjøtt, Jan; Böttiger, Ylva; Damkier, Per; Reppe, Linda Amundstuen; Kampmann, Jens Peter; Christensen, Hanne Rolighed; Spigset, Olav (Journal article, 2018)

  Background: The aim of this study was to compare use of references in responses from Scandinavian drug information centres (DICs). Methods: Six different fictitious drug-related queries were sent to each of seven Scandinavian ...

• Incidence of the diagnosis of factitious disorders - Nationwide comparison study between Germany and Norway 

  Geile, Julian; Aasly, Jan; Madea, Burkhard; Schrader, Harald (Peer reviewed; Journal article, 2020)

  Factitious disorders (FD) like Munchausen syndrome are well known to most physicians, yet the corresponding ICD-10 diagnosis F68.1 remains severely under-assigned and often misdiagnosed. To approach this problem, we conducted ...

• Corticosteroid injection for coccydynia: a review of 241 patients 

  Finsen, Vilhjalmur; Kalstad, Ante Matti; Knobloch, Rainer (Peer reviewed; Journal article, 2020)

  Aims We aimed to establish the short- and long-term efficacy of corticosteroid injection for coccydynia, and to determine if betamethasone or triamcinolone has the best effect. Methods During 2009 to 2016, we treated ...

• Intrapartum ultrasound assessment of cervical dilatation and its value in detecting active labor 

  Wiafe, Yaw A.; Whitehead, Bill; Venables, Heather; Dassah, Edward T.; Eggebø, Torbjørn Moe (Peer reviewed; Journal article, 2018)

  Introduction We aimed to examine the agreement between ultrasound and digital vaginal examination in assessing cervical dilatation in an African population and to assess the value of ultrasound in detecting active ...

• Predictors of community versus specialty mental health service use: a prospective cohort study 

  Brattfjell, Maria Larsen; Jozefiak, Thomas; Wichstrøm, Lars (Peer reviewed; Journal article, 2020)

  Child and adolescent mental health specialized services (CAMHS) are supposed to serve those who are most seriously disturbed and impaired. However, little is known about how children receiving treatment at different levels ...

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