• Lowering levels of reelin in entorhinal cortex layer II-neurons results in lowered levels of intracellular amyloid-β 

      Kobro-Flatmoen, Asgeir; Battistin, Claudia; Raveendran Nair, Rajeevkumar; Bjorkli, Christiana; Skender, Belma; Kentros, Clifford George; Gouras, Gunnar; Witter, Menno Peter (Peer reviewed; Journal article, 2023)
      Projection neurons in the anteriolateral part of entorhinal cortex layer II are the predominant cortical site for hyper-phosphorylation of tau and formation of neurofibrillary tangles in prodromal Alzheimer’s disease. A ...
    • Lowering of Circulating Sclerostin May Increase Risk of Atherosclerosis and its Risk Factors: Evidence From a Genome-Wide Association Meta-Analysis Followed by Mendelian Randomization 

      Zheng, Jie; Wheeler, Eleanor; Pietzner, Maik; Andlauer, Till F.M.; Yau, Michelle S.; Hartley, April E.; Brumpton, Ben Michael; Rasheed, Humaira; Kemp, John P.; Frysz, Monika; Robinson, Jamie; Reppe, Sjur; Prijatelj, Vid; Gautvik, Kaare M; Falk, Louise; Maerz, Winfried; Gergei, Ingrid; Peyser, Patricia A; Kavousi, Maryam; de Vries, Paul S.; Miller, Clint L.; Bos, Maxime; Van Der Laan, Sander W.; Malhotra, Rajeev; Herrmann, Markus; Scharnagl, Hubert; Kleber, Marcus; Dedoussis, George; Zeggini, Eleftheria; Nethander, Maria; Ohlsson, Claes; Lorentzon, Mattias; Wareham, Nick; Langenberg, Claudia; Holmes, Michael V.; Smith, George Davey; Tobias, Jonathan H. (Peer reviewed; Journal article, 2023)
      Objective In this study, we aimed to establish the causal effects of lowering sclerostin, target of the antiosteoporosis drug romosozumab, on atherosclerosis and its risk factors. Methods A genome-wide association ...
    • LPV model reference control for fixed-wing UAVs 

      Rotondo, Damiano; Cristofaro, Andrea; Gryte, Kristoffer; Johansen, Tor Arne (Journal article; Peer reviewed, 2017)
      This paper proposes a linear parameter varying (LPV) model reference-based control for fixed-wing unmanned aerial vehicles (UAVs), which achieves agile and high performance tracking objectives in extended flight envelopes, ...
    • LPWAN Cyber Security Risk Analysis: Building a Secure IQRF Solution 

      Bouzidi, Mohammed; Amro, Ahmed Walid; Dalveren, Yaser; Alaya Cheikh, Faouzi; Derawi, Mohammad (Peer reviewed; Journal article, 2023)
      Low-power wide area network (LPWAN) technologies such as IQRF are becoming increasingly popular for a variety of Internet of Things (IoT) applications, including smart cities, industrial control, and home automation. ...
    • LRRK2 to the rescue of damaged endomembranes 

      Radulovic, Maja; Stenmark, Harald Alfred (Peer reviewed; Journal article, 2020)
      Mutations in several genes encoding for lysosomal proteins are involved in Parkinson's disease (PD). In this issue, Herbst et al (2020) show that PD-related leucine-rich repeat kinase 2 (LRRK2) is activated in response to ...
    • LRRTM3 Interacts with APP and BACE1 and Has Variants Associating with Late-Onset Alzheimer's Disease (LOAD) 

      Lincoln, Sarah; Allen, Mariet; Cox, Claire L.; Walker, Louise P.; Malphrus, Kimberly; Qiu, Yishu; Nguyen, Thuy; Rowley, Christopher; Kouri, Naomi; Crook, Julia; Pankratz, V. Shane; Younkin, Samuel; Younkin, Linda; Carrasquillo, Minerva; Zou, Fang Geng; Abdul-Hay, Samer O.; Springer, Wolfdieter; Sando, Sigrid Botne; Aasly, Jan; Barcikowska, Maria; Wszolek, Zbigniew K.; Lewis, Jada M.; Dickson, Dennis; Graff-Radford, Neil R.; Petersen, Ronald C.; Eckman, Elizabeth; Younkin, Steven G.; Ertekin-Taner, Nilüfer (Journal article; Peer reviewed, 2013)
      Leucine rich repeat transmembrane protein 3 (LRRTM3) is member of a synaptic protein family. LRRTM3 is a nested gene within α-T catenin (CTNNA3) and resides at the linkage peak for late-onset Alzheimer’s disease (LOAD) ...
    • LS-CAT: A Large-Scale CUDA AutoTuning Dataset 

      Lars, Bjertnes; Tørring, Jacob; Elster, Anne C. (Peer reviewed; Journal article, 2021)
      The effectiveness of Machine Learning (ML) methods depend on access to large suitable datasets. In this article, we present how we build the LS-CAT (Large-Scale CUDA AutoTuning) dataset sourced from GitHub for the purpose ...
    • LSD1 represses a neonatal/reparative gene program in adult intestinal epithelium 

      Zwiggelaar, Rosalie; Lindholm, Håvard Takle; Fosslie, Madeleine Lystad; Pedersen, Marianne Terndrup; Ohta, Yuki; Díez-Sánchez, Alberto; Martín-Alonso, Mara; Ostrop, Jenny; Matono, Mami; Parmar, Naveen; Kvaløy, Emilie; Spanjers, Roos; Nazmi, Kamran; Rye, Morten Beck; Drabløs, Finn; Arrowsmith, Cheryl H; Dahl, John Arne; Jensen, Kim B.; Sato, Toshiro; Oudhoff, Menno (Journal article; Peer reviewed, 2020)
      Intestinal epithelial homeostasis is maintained by adult intestinal stem cells, which, alongside Paneth cells, appear after birth in the neonatal period. We aimed to identify regulators of neonatal intestinal epithelial ...
    • LSPR and Interferometric Sensor Modalities Combined Using a Double-Clad Optical Fiber 

      Muri, Harald Ian; Bano, Andon; Hjelme, Dag Roar (Journal article; Peer reviewed, 2018)
      We report on characterization of an optical fiber-based multi-parameter sensor concept combining localized surface plasmon resonance (LSPR) signal and interferometric sensing using a double-clad optical fiber. The sensor ...
    • LSPR Coupling and Distribution of Interparticle Distances between Nanoparticles in Hydrogel on Optical Fiber End Face 

      Muri, Harald Ian; Hjelme, Dag Roar (Journal article; Peer reviewed, 2017)
      We report on a new localized surface plasmon resonance (LSPR)-based optical fiber (OF) architecture with a potential in sensor applications. The LSPR-OF system is fabricated by immobilizing gold nanoparticles (GNPs) in a ...
    • LTE Uplink Transmission Scheme 

      Surgiewicz, Rafal; Strom, Niklas; Ahmed, Anser; Ai, Yun (Research report, 2014)
      The Long Term Evolution (LTE) standard requires an uplink transmission rate of up to 86 Mbps. In order to support such a high data rate and avoid the high Peak-to-Average Power Ratio (PAPR) disadvantage in Orthogonal-FDMA, ...
    • Luftede kledninger. Anbefalinger for klimatilpasning 

      Bunkholt, Nora Schjøth; Time, Berit; Kvande, Tore (Klima 2050 Report;, Research report, 2021)
    • De Luikse muntslag te Maastricht 1541-1543 

      Benders, Jos (Peer reviewed; Journal article, 2021)
    • Luksus i Luster. Høgendeskirken Urnes 

      Stang, Margrethe C. (Journal article; Peer reviewed, 2017)
      Urnes kirke regnes av mange som den største juvelen i Fortidsminneforeningens eiendomsportefølje. Stavkirken er spektakulært plassert på odden Ornes,1 med høye berg over seg og bratte skråninger ned mot Lustrafjorden under ...
    • Lumbar total disc replacement: predictors for long-term outcome 

      Furunes, Håvard; Hellum, Christian; Brox, Jens Ivar; Rossvoll, Ivar; Espeland, Ansgar; Berg, Linda; Brøgger, Helga Maria; Småstuen, Milada C; Storheim, Kjersti (Journal article; Peer reviewed, 2017)
      Purpose We aimed to identify patient characteristics associated with favourable long-term outcomes after lumbar total disc replacement (TDR). Methods We analysed a cohort of 82 patients with degenerative disc and ...
    • Luminescent Eu3+-doped NaLa(WO4)(MoO4) and Ba2CaMoO6 prepared by the modified Pechini method 

      Sletnes, Malin; Skjærvø, Susanne Linn; Lindgren, Mikael; Grande, Tor; Einarsrud, Mari-Ann (Journal article; Peer reviewed, 2016)
      Modified Pechini synthesis routes were developed for synthesis of the novel red phosphor materials NaLa(WO4)(MoO4):Eu3+ and Ba2CaMoO6:Eu3+. Phase pure NaLa(WO4)(MoO4):Eu3+ was obtained at calcination temperatures ≥600 °C ...
    • Lumped, constrained cable modeling with explicit state-space formulation using an elastic version of Baumgarte stabilization 

      Skjong, Stian; Reite, Karl-Johan; Aarsæther, Karl Gunnar (Peer reviewed; Journal article, 2021)
      This paper presents a modeling approach for efficient simulation of slender structures, such as wires, cables and ropes.Lumped structural elements are connected using constraints.These are solved explicitly, using an elastic ...
    • Lung cancer risk discrimination of prediagnostic proteomics measurements compared with existing prediction tools 

      Feng, Xiaoshuang; Wu, Wendy Yi-Ying; Onwuka, Justina Ucheojor; Haider, Zahra; Alcala, Karine; Smith-Byrne, Karl; Zahed, Hana; Guida, Florence; Wang, Renwei; Bassett, Julie K.; Stevens, Victoria; Wang, Ying; Weinstein, Stephanie; Freedman, Neal D.; Chen, Chu; Tinker, Lesley; Nøst, Therese Haugdahl; Koh, Woon-Puay; Muller, David; Colorado-Yohar, Sandra M.; Tumino, Rosario; Hung, Rayjean J.; Amos, Christopher I.; Lin, Xihong; Zhang, Xuehong; Arslan, Alan A.; Sánchez, Maria-Jose; Sørgjerd, Elin Pettersen; Severi, Gianluca; Hveem, Kristian; Brennan, Paul; Langhammer, Arnulf; Milne, Roger L.; Yuan, Jian-Min; Melin, Beatrice; Johansson, Mikael; Robbins, Hilary A.; Johansson, Mattias (Peer reviewed; Journal article, 2023)
      Background We sought to develop a proteomics-based risk model for lung cancer and evaluate its risk-discriminatory performance in comparison with a smoking-based risk model (PLCOm2012) and a commercially available ...
    • Lung function and peak oxygen uptake in chronic obstructive pulmonary disease phenotypes with and without emphysema 

      Rasch-Halvorsen, Øystein; Steinshamn, Sigurd Loe; Langhammer, Arnulf; Hassel, Erlend; Brumpton, Ben Michael; Jenssen, Haldor; Spruit, Martijn A. (Journal article; Peer reviewed, 2021)
      Previous studies of associations of forced expiratory lung volume in one second (FEV1) with peak oxygen uptake (VO2peak) in chronic obstructive pulmonary disease (COPD) have not taken sex, age and height related variance ...
    • Lung function in adults born preterm 

      Nasanen-Gilmore, Pieta; Sipola-Leppänen, Marika; Tikanma Ki, Marjaana; Matinolli, Hanna-Maria; Eriksson, Johan G; Järvelin, Marjo-Riitta; Vaarasma Ki, Marja; Hovi, Petteri; Kajantie, Eero (Journal article; Peer reviewed, 2018)
      Very preterm birth, before the gestational age (GA) of 32 weeks, increases the risk of obstructed airflow in adulthood. We examined whether all preterm births (GA<37 weeks) are associated with poorer adult lung function ...