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dc.contributor.authorGjellesvik, Tor Ivar
dc.contributor.authorBecker, Frank
dc.contributor.authorTjønna, Arnt Erik
dc.contributor.authorIndredavik, Bent
dc.contributor.authorNilsen, Halvard Knut
dc.contributor.authorBrurok, Berit
dc.contributor.authorTørhaug, Tom
dc.contributor.authorBusuladzic, Maja
dc.contributor.authorLydersen, Stian
dc.contributor.authorAskim, Torunn
dc.date.accessioned2021-02-12T07:11:20Z
dc.date.available2021-02-12T07:11:20Z
dc.date.created2021-01-04T15:11:54Z
dc.date.issued2020
dc.identifier.citationArchives of Physical Medicine and Rehabilitation. 2020, 101 (6), 939-947.en_US
dc.identifier.issn0003-9993
dc.identifier.urihttps://hdl.handle.net/11250/2727550
dc.description.abstractObjective To examine if 8 weeks of high-intensity interval training (HIIT) in addition to standard care would increase and maintain peak oxygen uptake (Vo2peak) more than standard care alone in patients with stroke. Design This was a single-blind, multicenter, parallel group, randomized controlled trial. Setting Specialized rehabilitation units at 3 Norwegian hospitals. Participants Participants (N=70), 3 months to 5 years after first-ever stroke, were randomly assigned to the intervention group (n=36) or the control group (n=34); 42% were women, mean age was 57.6±9.3 years, mean time post stroke was 26.4±14.5 months. Intervention The intervention was 8 weeks: 3 times a week with HIIT treadmill training with work periods of 4 × 4 minutes at 85%-95% of peak heart rate interspersed with 3 minutes of active recovery at 50%-70% of peak heart rate. The control group received standard care according to national guidelines. Outcomes The primary outcome, analyzed by intention-to-treat, was Vo2peak measured as liters per minute 12 months after inclusion. Secondary outcome measures were blood pressure and blood profile. Results Mean baseline Vo2peak was 2.63±1.08 L·min−1 vs 2.87±0.71 L·min−1, while at 12 months Vo2peak was 2.70±1.00 L·min−1 vs 2.67±0.76 L·min−1 (P=.068) in the intervention and control groups, respectively. There was a significant and greater improvement in the intervention group compared with the control group at 12 months in 3 of 6 secondary outcomes from the peak test but no significant differences for blood pressure or blood profile. Conclusions The HIIT intervention, which was well-tolerated in this sample of well-functioning survivors of stroke, was not superior to standard care in improving and maintaining Vo2peak at the 12-month follow-up. However, secondary results from the peak test showed a significant improvement from before to immediately after the intervention.en_US
dc.language.isoengen_US
dc.publisherElsevieren_US
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internasjonal*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/deed.no*
dc.titleEffects of High-Intensity Interval Training After Stroke (the HIIT-Stroke Study): A Multicenter Randomized Controlled Trialen_US
dc.typePeer revieweden_US
dc.typeJournal articleen_US
dc.description.versionacceptedVersionen_US
dc.source.pagenumber939-947en_US
dc.source.volume101en_US
dc.source.journalArchives of Physical Medicine and Rehabilitationen_US
dc.source.issue6en_US
dc.identifier.doi10.1016/j.apmr.2020.02.006
dc.identifier.cristin1865005
dc.description.localcode"© 2020. This is the authors’ accepted and refereed manuscript to the article. Locked until 4.3.2021 due to copyright restrictions. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ "en_US
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.fulltextpostprint
cristin.qualitycode1


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