dc.contributor.author | Gjellesvik, Tor Ivar | |
dc.contributor.author | Becker, Frank | |
dc.contributor.author | Tjønna, Arnt Erik | |
dc.contributor.author | Indredavik, Bent | |
dc.contributor.author | Nilsen, Halvard Knut | |
dc.contributor.author | Brurok, Berit | |
dc.contributor.author | Tørhaug, Tom | |
dc.contributor.author | Busuladzic, Maja | |
dc.contributor.author | Lydersen, Stian | |
dc.contributor.author | Askim, Torunn | |
dc.date.accessioned | 2021-02-12T07:11:20Z | |
dc.date.available | 2021-02-12T07:11:20Z | |
dc.date.created | 2021-01-04T15:11:54Z | |
dc.date.issued | 2020 | |
dc.identifier.citation | Archives of Physical Medicine and Rehabilitation. 2020, 101 (6), 939-947. | en_US |
dc.identifier.issn | 0003-9993 | |
dc.identifier.uri | https://hdl.handle.net/11250/2727550 | |
dc.description.abstract | Objective: To examine if 8 weeks of high-intensity interval training (HIIT) in addition to standard care would increase and maintain peak oxygen uptake (Vo2peak) more than standard care alone in patients with stroke.
Design: This was a single-blind, multicenter, parallel group, randomized controlled trial.
Setting: Specialized rehabilitation units at 3 Norwegian hospitals.
Participants: Participants (N=70), 3 months to 5 years after first-ever stroke, were randomly assigned to the intervention group (n=36) or the control group (n=34); 42% were women, mean age was 57.6±9.3 years, mean time post stroke was 26.4±14.5 months.
Intervention: The intervention was 8 weeks: 3 times a week with HIIT treadmill training with work periods of 4 × 4 minutes at 85%-95% of peak heart rate interspersed with 3 minutes of active recovery at 50%-70% of peak heart rate. The control group received standard care according to national guidelines.
Outcomes: The primary outcome, analyzed by intention-to-treat, was Vo2peak measured as liters per minute 12 months after inclusion. Secondary outcome measures were blood pressure and blood profile.
Results: Mean baseline Vo2peak was 2.63±1.08 L·min−1 vs 2.87±0.71 L·min−1, while at 12 months Vo2peak was 2.70±1.00 L·min−1 vs 2.67±0.76 L·min−1 (P=.068) in the intervention and control groups, respectively. There was a significant and greater improvement in the intervention group compared with the control group at 12 months in 3 of 6 secondary outcomes from the peak test but no significant differences for blood pressure or blood profile.
Conclusions:The HIIT intervention, which was well-tolerated in this sample of well-functioning survivors of stroke, was not superior to standard care in improving and maintaining Vo2peak at the 12-month follow-up. However, secondary results from the peak test showed a significant improvement from before to immediately after the intervention. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Elsevier | en_US |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internasjonal | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/deed.no | * |
dc.title | Effects of High-Intensity Interval Training After Stroke (the HIIT-Stroke Study): A Multicenter Randomized Controlled Trial | en_US |
dc.type | Peer reviewed | en_US |
dc.type | Journal article | en_US |
dc.description.version | publishedVersion | en_US |
dc.source.pagenumber | 939-947 | en_US |
dc.source.volume | 101 | en_US |
dc.source.journal | Archives of Physical Medicine and Rehabilitation | en_US |
dc.source.issue | 6 | en_US |
dc.identifier.doi | 10.1016/j.apmr.2020.02.006 | |
dc.identifier.cristin | 1865005 | |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |