Browsing St. Olavs hospital by Title
Now showing items 990-1009 of 2441
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Hexadirectional coding of visual space in human entorhinal cortex
(Journal article; Peer reviewed, 2018)Entorhinal grid cells map the local environment, but their involvement beyond spatial navigation remains elusive. We examined human functional MRI responses during a highly controlled visual tracking task and show that ... -
High arterial oxygen levels and supplemental oxygen administration in traumatic brain injury: insights from CENTER-TBI and OzENTER-TBI
(Peer reviewed; Journal article, 2022)Purpose The effect of high arterial oxygen levels and supplemental oxygen administration on outcomes in traumatic brain injury (TBI) is debated, and data from large cohorts of TBI patients are limited. We investigated ... -
A high cerebrospinal fluid soluble TREM2 level is associated with slow clinical progression of Alzheimer's disease
(Peer reviewed; Journal article, 2020)Introduction: The progression rate of Alzheimer's disease (AD) varies and might be affected by the triggering receptor expressed on myeloid cells (TREM2) activity. We explored if cerebrospinal fluid (CSF) soluble TREM2 ... -
High concentrations of soluble endoglin can inhibit BMP9 signaling in non-endothelial cells
(Peer reviewed; Journal article, 2023)Endoglin (ENG) is a single-pass transmembrane protein highly expressed on vascular endothelial cells, although low expression levels can be detected in many other cell types. Its extracellular domain can be found in ... -
High incidence and prevalence of MS in Møre and Romsdal County, Norway, 1950–2018
(Peer reviewed; Journal article, 2020)Objective To determine prevalence and longitudinal trends in incidence of MS in Møre and Romsdal County, Western Norway, from 1950 to 2018. Methods Retrospective longitudinal population-based observational study. All ... -
High Levels of Complement Activating Enzyme MASP-2 Are Associated With the Risk of Future Incident Venous Thromboembolism
(Peer reviewed; Journal article, 2022)Background: Experimental studies have shown that the complement activating enzyme MASP-2 (mannose-binding lectin associated serine protease 2) exhibits a thrombin-like activity and that inhibition of MASP-2 protects ... -
High levels of discordant antimicrobial therapy in hospital-acquired bloodstream infections is associated with increased mortality in an intensive care, low antimicrobial resistance setting
(Peer reviewed; Journal article, 2022)Background Bloodstream infections (BSI) occur frequently and are associated with severe outcomes. In this study we aimed to investigate proportions of patients that received discordant empirical antimicrobial therapy and ... -
High neuroticism is associated with reduced negative affect following sleep deprivation
(Peer reviewed; Journal article, 2021)The aim was to investigate how neuroticism moderates the affective consequences of personalized mild-moderate partial sleep deprivation. A total of 52 healthy subjects aged 18–35 years completed the NEO PI-3 at baseline, ... -
High prevalence of vertebral fractures and low trabecular bone score in patients with fragility fractures: A cross-sectional sub-study of NoFRACT
(Peer reviewed; Journal article, 2019)Purpose - Norway has among the highest incidence rates of fractures in the world. Vertebral fracture assessment (VFA) and trabecular bone score (TBS) provide information about fracture risk, but their importance have not ... -
High sensitivity C-reactive protein and risk of migraine in a 11-year follow-up with data from the Nord-Trøndelag health surveys 2006–2008 and 2017–2019
(Peer reviewed; Journal article, 2020)Background Several previous studies have reported a cross-sectional association between elevated high sensitivity C-reactive protein (hs-CRP) and migraine. The aim of this population-based follow-up study was to investigate ... -
High ward occupancy, bedspacing, and 60 day mortality for patients with myocardial infarction, stroke, and heart failure
(Journal article; Peer reviewed, 2022)Abstract Aims To study the consequences of crowded wards among patients with cardiovascular disease. Methods and results This is a cohort study among 201 801 patients with 258 807 admissions who were acutely admitted for ... -
High-density lipoprotein subfractions: Much ado about nothing or clinically important?
(Peer reviewed; Journal article, 2021)High-density lipoproteins (HDL) are a heterogenous group of plasma molecules with a large variety in composition. There is a wide specter in lipid content and the number of different proteins that has been associated with ... -
High-intensity exergaming for improved cardiorespiratory fitness: A randomised, controlled trial
(Peer reviewed; Journal article, 2021)Exergaming has been proposed as a promising alternative to traditional endurance training since many experience exergaming as more enjoyable. Therefore, the aim of this trial was to determine the exergaming-induced effect ... -
High-intensity exergaming for improved cardiorespiratory fitness: A randomised, controlled trial
(Peer reviewed; Journal article, 2022)Exergaming has been proposed as a promising alternative to traditional endurance training since many experience exergaming as more enjoyable. Therefore, the aim of this trial was to determine the exergaming-induced effect ... -
High-intensity interval training and pulmonary hemodynamics in COPD with hypoxemia
(Peer reviewed; Journal article, 2021)Background Exercise is recommended for all patients with COPD. Evidence for its benefit is considerably weaker in the more severe stages of the disease. The aim of this study was to investigate whether high-intensity ... -
High-intensity interval training in polycystic ovary syndrome: a two-centre, three-armed randomized controlled trial
(Peer reviewed; Journal article, 2021)Purpose Exercise training is recommended to improve cardiometabolic health and fertility in women with polycystic ovary syndrome (PCOS), yet there are few randomized controlled trials on the effects of different exercise ... -
High-sensitivity C-reactive protein is related to age and gender in an acute psychiatric inpatient population
(Journal article; Peer reviewed, 2022)Increased levels of high-sensitivity C-reactive protein (hsCRP) is associated with several psychiatric disorders. Demographic factors such as age and gender might affect this association, but the results are conflicting. ... -
Higher blood pressure in normal weight women with pcos compared to controls
(Peer reviewed; Journal article, 2021)Objective Obesity is considered to be the strongest predictive factor for cardio-metabolic risk in women with polycystic ovary syndrome (PCOS). The aim of the study was to compare blood pressure (BP) in normal weight women ... -
Higher concentrations of kynurenic acid in CSF are associated with the slower clinical progression of Alzheimer's disease
(Peer reviewed; Journal article, 2023)INTRODUCTION The kynurenine pathway's (KP) malfunction is closely related to Alzheimer's disease (AD), for antagonistic kynurenic acid (KA) and agonistic quinolinic acid act on the N-methyl-D-aspartate receptor, a ... -
Higher vitamin B12 levels in neurodevelopmental disorders than in healthy controls and schizophrenia A comparison among participants between 2 and 53 years
(Peer reviewed; Journal article, 2020)Recent studies suggest that both high and low levels of vitamin B12 (vitB12) may have negative health impacts. We measured VitB12 in patients with the Neurodevelopmental disorders (ND) (n = 222), comprised of Autism Spectrum ...