Browsing St. Olavs hospital by Title
Now showing items 2346-2365 of 2620
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T1 bladder cancer in Norway: treatment and survival
(Peer reviewed; Journal article, 2020)Aim: Evaluation of treatment and survival of pT1 stage (T1) bladder cancer (BC) patients diagnosed with transitional cell carcinoma of the urinary bladder in Norway. Material and methods: According to the Cancer Registry ... -
Tailored surgery in chronic pancreatitis after implementation of a multidisciplinary team assessment; a prospective observational study
(Peer reviewed; Journal article, 2022)Introduction - Optimal management of chronic pancreatitis involves several specialties. Selection of patients for surgery may benefit from evaluation by a multidisciplinary team (MDT), similar to cancer care. The aim of ... -
Tailoring Multi-Dimensional Outcomes to Level of Functional Recovery after Traumatic Brain Injury
(Peer reviewed; Journal article, 2022)There is increasing emphasis on assessing multi-dimensional outcomes in traumatic brain injury (TBI), but achieving this aim is hampered by a plethora of overlapping assessment tools. There is a clear need for advice on ... -
TAK1-inhibitors did not reduce disease burden in a Vκ*MYC model of multiple myeloma
(Peer reviewed; Journal article, 2022)Objective Multiple myeloma is a haematological malignancy characterized by proliferation of monoclonal plasma cells in the bone marrow. Development of resistance and minimal residual disease remain challenging in the ... -
Take-home naloxone for the emergency interim management of opioid overdose: The public health application of an emergency medicine
(Peer reviewed; Journal article, 2019)Naloxone is a well-established essential medicine for the treatment of life-threatening heroin/opioid overdose in emergency medicine. Over two decades, the concept of ‘take-home naloxone’ has evolved, comprising pre-provision ... -
Taller height and risk of coronary heart disease and cancer: A within-sibship Mendelian randomization study
(Peer reviewed; Journal article, 2022)Background: Taller people have a lower risk of coronary heart disease but a higher risk of many cancers. Mendelian randomization (MR) studies in unrelated individuals (population MR) have suggested that these relationships ... -
Targeted sequencing of genes associated with the mismatch repair pathway in patients with endometrial cancer
(Peer reviewed; Journal article, 2020)Germline variants inactivating the mismatch repair (MMR) genes MLH1, MSH2, MSH6 and PMS2 cause Lynch syndrome that implies an increased cancer risk, where colon and endometrial cancer are the most frequent. Identification ... -
Targeting a therapeutically relevant concentration of alendronate for in vitro studies on osteoblasts
(Peer reviewed; Journal article, 2022)Objective Bisphosphonates like alendronate mainly exert their effects on osteoclasts. However, osteoblasts are also affected, but exposed to a much lower concentration in vivo than the osteoclasts. Given that the effects ... -
Targeting Internalizing Symptoms in Children: What is the Impact on School Functioning?
(Peer reviewed; Journal article, 2022)Internalizing problems may be associated with poor academic performance and school absenteeism among youth. This study investigated the impact of the EMOTION: “Coping Kids” Managing Anxiety and Depression Program on academic ... -
Targeting Internalizing Symptoms in Children: What is the Impact on School Functioning?
(Peer reviewed; Journal article, 2022)Internalizing problems may be associated with poor academic performance and school absenteeism among youth. This study investigated the impact of the EMOTION: “Coping Kids” Managing Anxiety and Depression Program on academic ... -
Targeting phosphoglycerate dehydrogenase in multiple myeloma
(Peer reviewed; Journal article, 2021)Background: Multiple myeloma (MM) is a hematological malignancy characterized by the clonal expansion of plasma cells in the bone marrow. To date, this disease is still incurable and novel therapeutic approaches are required. ... -
Team approach: Multidisciplinary treatment of hip fractures in elderly patients: Orthogeriatric care
(Journal article; Peer reviewed, 2019)Patients with hip fractures are best managed by a multidisciplinary team. The multidisciplinary team consists of an orthogeriatrician, orthopaedic surgeon, aanesthesiologist, orthopaedic and/or geriatric nurse, occupational ... -
Technologies for assessment of bone reflecting bone strength and bone mineral density in elderly women: An update
(Peer reviewed; Journal article, 2016)Reduced bone mineral density is a strong risk factor for fracture. The WHO’s definition of osteoporosis is based on bone mineral density measurements assessed by dual x-ray absorptiometry. Several on other techniques than ... -
Template for documenting and reporting data in physician-staffed pre-hospital services: a consensus-based update
(Peer reviewed; Journal article, 2020)Background: Physician-staffed emergency medical services (p-EMS) are resource demanding, and research is needed to evaluate any potential effects of p-EMS. Templates, designed through expert agreement, are valuable and ... -
Ten-Year Cardiovascular Disease Risk Trajectories by Obstetric History: A Longitudinal Study in the Norwegian HUNT Study
(Peer reviewed; Journal article, 2022)Background Women with a history of obstetric complications are at increased risk of cardiovascular disease, but whether they should be specifically targeted for cardiovascular disease (CVD) risk screening is unknown. Methods ... -
Tenecteplase in wake-up ischemic stroke trial: Protocol for a randomized-controlled trial
(Peer reviewed; Journal article, 2021)Background: Patients with wake-up ischemic stroke who have evidence of salvageable tissue on advanced imaging can benefit from intravenous thrombolysis. It is not known whether patients who do not fulfil such imaging ... -
Terminating Routine Cord Blood RhD Typing of the Newborns to Guide Postnatal Anti-D Immunoglobulin Prophylaxis Based on the Results of Fetal RHD Genotyping
(Peer reviewed; Journal article, 2023)Introduction: Targeted routine antenatal prophylaxis with anti-D immunoglobulin (Ig) only to RhD-negative pregnant women who carry RhD-positive fetuses (determined by fetal RHD genotyping) has reduced D-alloimmunization ... -
Terminology and ontology development for semantic annotation: A use case on sepsis and adverse events
(Peer reviewed; Journal article, 2023)Annotations enrich text corpora and provide necessary labels for natural language processing studies. To reason and infer underlying implicit knowledge captured by labels, an ontology is needed to provide a semantically ... -
Test Accuracy of the Montreal Cognitive Assessment in Screening for Early Poststroke Neurocognitive Disorder
(Peer reviewed; Journal article, 2020)Background. Human immunodeficiency virus (HIV)–infected immunological nonresponders (INRs) fail to reconstitute their CD4+ T-cell pool after initiation of antiretroviral therapy, and their prognosis is inferior to that of ... -
Test-retest reliability of the patient activation measure-13 in adults with substance use disorders and schizophrenia spectrum disorders
(Peer reviewed; Journal article, 2021)Patient Activation Measure-13 (PAM-13) is a valid and widely used questionnaire that assess an individual’s knowledge, confidence, and skills for self-management of their chronic illness. Although there is some evidence ...