• Development of a predictive model for patients with bone metastases referred to palliative radiotherapy: Secondary analysis of a multicenter study (the PRAIS trial) 

  Rossi, Romina; Medici, Federica; Habberstad, Ragnhild Hansdatter; Klepstad, Pål; Cilla, Savino; Dall'Agata, Monia; Kaasa, Stein; Caraceni, Augusto Tomasso Giovanni; Morganti, Alessio Giuseppe; Maltoni, Marco (Journal article; Peer reviewed, 2024)

  Background: The decision to administer palliative radiotherapy (RT) to patients with bone metastases (BMs), as well as the selection of treatment protocols (dose, fractionation), requires an accurate assessment of survival ...

• Single cell and spatial transcriptomics highlight the interaction of club-like cells with immunosuppressive myeloid cells in prostate cancer 

  Kiviaho, Antti; Eerola, Sini K.; Kallio, Heini M.L.; Andersen, Maria K.; Hoikka, Miina; Salonen, Iida; Spotbeen, Xander; Giesen, Alexander; Parker, Charles T.A.; Taavitsainen, Sinja; Hantula, Olli; Marttinen, Mikael; Harmelo, Ismael; Ismail, Mazlina; Midtbust, Elise; Wess, Maximilian; Devlies, Wout; Sharma, Abhibhav; Krossa, Sebastian; Häkkinen, Tomi; Afyounian, Ebrahim; Vandereyken, Katy; Kint, Sam; Kesseli, Juha; Tolonen, Teemu; Tammela, Teuvo L.J.; Viset, Trond; Størkersen, Øystein; Giskeødegård, Guro F.; Rye, Morten Beck; Murtola, Teemu; Erickson, Andrew; Latonen, Leena; Bova, Steven G.; Mills, Ian Geoffrey; Joniau, Steven; Swinnen, Johannes V.; Voet, Thierry; Mirtti, Tuomas; Attard, Gerhardt; Claessens, Frank; Visakorpi, Tapio; Rautajoki, Kirsi J.; Tessem, May-Britt; Urbanucci, Alfonso; Nykter, Matti; Tiihonen, Aliisa M. (Journal article; Peer reviewed, 2024)

  Prostate cancer treatment resistance is a significant challenge facing the field. Genomic and transcriptomic profiling have partially elucidated the mechanisms through which cancer cells escape treatment, but their relation ...

• Progression-free survival versus post-progression survival and overall survival in WHO grade 2 gliomas 

  Sagberg, Lisa Millgård; Salvesen, Øyvind Olav; Jakola, Asgeir Store; Thurin, Erik; De Dios, Eddie; Nawabi, Noah L.A; Kilgallon, John L.; Bernstock, Joshua D.; Kavouridis, Vasileios; Smith, Timothy R.; Solheim, Ole Skeidsvoll (Journal article; Peer reviewed, 2024)

  Background and purpose: Progression-free survival (PFS) remains to be validated as an outcome measure for diffuse WHO grade 2 gliomas, and knowledge about the relationships between PFS, post-progression survival (PPS), and ...

• Single-cell multiomics analysis of chronic myeloid leukemia links cellular heterogeneity to therapy response 

  Warfvinge, Rebecca; Geironson Ulfsson, Linda; Dhapola, Parashar; Safi, Fatemeh; Sommarin, Mikael; Soneji, Shamit; Hjorth-Hansen, Henrik; Mustjoki, Satu; Richter, Johan; Thakur, Ram Krishna; Karlsson, Göran (Journal article; Peer reviewed, 2024)

  The advent of tyrosine kinase inhibitors (TKIs) as treatment of chronic myeloid leukemia (CML) is a paradigm in molecularly targeted cancer therapy. Nonetheless, TKI-insensitive leukemia stem cells (LSCs) persist in most ...

• Systematic review and meta-analysis of birth outcomes in women with polycystic ovary syndrome 

  Bahri Khomami, Mahnaz; Hashemi, Somayeh; Shorakae, Soulmaz; Harrison, Cheryce L.; Piltonen, Terhi T.; Romualdi, Daniela; Tay, Chau Thien; Mousa, Aya; Vanky, Eszter Ilona; Teede, Helena J. (Journal article; Peer reviewed, 2024)

  It is unclear whether polycystic ovary syndrome (PCOS) is an independent risk factor for adverse birth outcomes in the offspring of affected women. Here, we investigate the association of PCOS with birth outcomes in the ...

• X-bundet hypofosfatemi 

  Wang, Qidi; Akdeniz, Cennet; Heck, Ansgar; Bjørk, Mai Britt; Theisen, Ole Rasmus; Eggesbø, Heidi Beate; Krüger, Tormod Bjartveit; Reseland, Janne Elin; Pihlstrøm, Hege Kampen; Åsvold, Bjørn Olav; Grimnes, Guri; Grytaas, Marianne Aardal; Rafaelsen, Silje Hjorth; Thorsby, Per Medbøe; Wekre, Lena Lande; Finnes, Trine Elisabeth (Journal article; Peer reviewed, 2025)

  X-bundet hypofosfatemi er en sjelden genetisk sykdom som medfører fosfattap i nyrene, redusert mineralisering av tenner og skjelett, deformerte knokler og begrenset mobilitet. Dette har betydelige konsekvenser for helse ...

• Effect of tocilizumab on endothelial and platelet-derived CXC-chemokines and their association with inflammation and myocardial injury in STEMI patients undergoing primary PCI 

  Woxholt, Sindre; Ueland, Thor; Aukrust, Pål; Anstensrud, Anne Kristine; Broch, Kaspar; Tøllefsen, Ingvild Maria; Seljeflot, Ingebjørg; Halvorsen, Bente; Dahl, Tuva Børresdatter; Huse, Camilla; Andersen, Geir Øystein; Gullestad, Lars; Wiseth, Rune; Damås, Jan Kristian; Kleveland, Ola (Journal article; Peer reviewed, 2025)

  Background: Tocilizumab improves myocardial salvage in ST-elevation myocardial infarction (STEMI) patients when administered before percutaneous coronary intervention (PCI). The mechanisms underlying ischemia-reperfusion ...

• Deep learning-based postoperative glioblastoma segmentation and extent of resection evaluation: Development, external validation, and model comparison 

  Cepeda, Santiago; Romero, Roberto; Luque, Lidia; García-Pérez, Daniel; Blasco, Guillermo; Luppino, Luigi Tommaso; Kuttner, Samuel; Esteban-Sinovas, Olga; Arrese, Ignacio; Solheim, Ole Skeidsvoll; Eikenes, Live; Karlberg, Anna Maria; Pérez-Núñez, Ángel; Zanier, Olivier; Serra, Carlo; Staartjes, Victor E.; Bianconi, Andrea; Rossi, Luca Francesco; Garbossa, Diego; Escudero, Trinidad; Hornero, Roberto; Sarabia, Rosario (Journal article; Peer reviewed, 2024)

  Background: The pursuit of automated methods to assess the extent of resection (EOR) in glioblastomas is challenging, requiring precise measurement of residual tumor volume. Many algorithms focus on preoperative scans, ...

• Contraction of Respiratory Viral Infection During air Travel: An Under-Recognized Health Risk for Athletes 

  Ruuskanen, Olli; Døllner, Henrik; Luoto, Raakel; Valtonen, Maarit; Heinonen, Olli J.; Waris, Matti (Journal article; Peer reviewed, 2024)

  Air travel has an important role in the spread of viral acute respiratory infections (ARIs). Aircraft offer an ideal setting for the transmission of ARI because of a closed environment, crowded conditions, and close-contact ...

• Repeat Prostate-specific Antigen Testing Improves Risk-based Selection of Men for Prostate Biopsy After Magnetic Resonance Imaging 

  Davik, Petter; Elschot, Mattijs; Bathen, Tone Frost; Bertilsson, Helena Maria (Journal article; Peer reviewed, 2024)

  Background and objective: The aim of our study was to investigate whether repeat prostate-specific antigen (PSA) testing as currently recommended improves risk stratification for men undergoing magnetic resonance imaging ...

• Application of Photodynamic Therapy with 5-Aminolevulinic Acid to Extracorporeal Photopheresis in the Treatment of Cutaneous T-Cell Lymphoma: A First-in-Human Phase I/II Study 

  Christensen, Eidi; Foss, Olav A.; Holien, Toril; Juzenas, Petras; Qian, Peng (Journal article; Peer reviewed, 2024)

  Extracorporeal photopheresis (ECP) is a therapeutic modality used for T-cell-mediated disorders. This approach involves exposing isolated white blood cells to photoactivatable 8-methoxypsoralen (8-MOP) and UVA light, aiming ...

• Omission of Radiotherapy in Primary Mediastinal B-Cell Lymphoma: IELSG37 Trial Results 

  Martelli, Maurizio; Ceriani, Luca; Ciccone, Giovannino; Ricardi, Umberto; Kriachok, Iryna; Botto, Barbara; Balzarotti, Monica; Tucci, Alessandra; Usai, Sara Veronica; Zilioli, Vittorio Ruggero; Pennese, Elsa; Arcaini, Luca; Dabrowska-Iwanicka, Anna; Ferreri, Andrés J.M.; Merli, Francesco; Zhao, Weili; Rigacci, Luigi; Cellini, Claudia; Hodgson, David; Ionescu, Codruta; Minoia, Carla; Lucchini, Elisa; Spina, Michele; Fosså, Alexander; Janikova, Andrea; Cwynarski, Kate; Mikhaeel, George; Jerkeman, Mats; Di Rocco, Alice; Stepanishyna, Yana; Vitolo, Umberto; Santoro, Armando; Re, Alessandro; Puccini, Benedetta; Olivieri, Jacopo; Petrucci, Luigi; Barrington, Sally F.; Malkowski, Bogdan; Metser, Ur; Versari, Annibale; Chauvie, Stephane; Walewski, Jan; Trneny, Marek; Cavalli, Franco; Gospodarowicz, Mary; Johnson, Peter W.M.; Davies, Andrew; Zucca, Emanuele; Kuruvilla, John; Wang, Li; Balada, David; Mocikova, Heidi; Huettmann, Andreas; Angrilli, Francesco; Annibali, Ombretta; Arcaini, Luca; Bagni, Oreste; Battistini, Roberta; Cabras, Maria Giuseppina; Calimeri, Teresa; Catello, Califano; Cavallo, Federica; Ciammella, Patrizia; Consoli, Ugo; De Sanctis, Vitaliana; Di Renzo, Nicola; Fabbri, Alberto; Ferrari, Angela; Flenghi, Leonardo; Gaidano, Gianluca; Gini, Guido; Gotti, Manuel; Guarini, Attilio; Liberati, Anna Marina; Mannina, Donato; Matrone, Fabio; Molinari, Anna Lia; Musuraca, Gerardo; Nassi, Luca; Passamonti, Francesco; Pastore, Domenico; Patti, Caterina; Pelliccia, Sabrina; Piazza, Francesco; Pisani, Francesco; Pizzuti, Michele; Pozzi, Samantha; Ravano, Emanuele; Re, Francesca; Sassone, Marianna; Stefoni, Vittorio; Stelitano, Caterina; Tarantini, Giuseppe; Tarella, Corrado; Vallisa, Daniele; Zaja, Francesco; Zanni, Manuela; Fagerli, Unn Merete; DaSilva, Maria Gomes; Azinwi, Ngwa Che; Deantonio, Letizia; Hitz, Felicitas; Mingrone, Walter; Moccia, Alden; Novak, Urban; Pirosa, Maria Cristina; Stathis, Anastasios; Cozens, Kelly; Fox, Christopher P.; Illidge, Timothy; Johnson, Rod; McKay, Pam; Milne, Alison; Nimish, Shah; Osborne, Wendy; Paneesha, Shankara; Pettitt, Andrew; Stevens, Don Ambrose; Bonomini, Luisella; Ielmini, Nicoletta (Peer reviewed; Journal article, 2024)

  Purpose The role of consolidation radiotherapy in patients with primary mediastinal B-cell lymphoma (PMBCL) is controversial. Methods The IELSG37 trial, a randomized noninferiority study, aimed to assess whether irradiation ...

• Contactless and continuous monitoring of respiratory rate in a hospital ward: a clinical validation study 

  Toften, Ståle; Kjellstadli, Jonas Tøgersen; Kværness, Jørn; Pedersen, Line; Laugsand, Lars Erik; Thu, Ole Kristian Forstrønen (Journal article; Peer reviewed, 2024)

  Introduction: Continuous monitoring of respiratory rate in hospital wards can provide early detection of clinical deterioration, thereby reducing mortality, reducing transfers to intensive care units, and reducing the ...

• Healthcare professionals’ experiences of interdisciplinary collaboration in pain centres – A qualitative study 

  Nøst, Torunn Hatlen; Dahl-Michelsen, Tone; Aandahl, Hanne; Steinsbekk, Aslak Irgens (Peer reviewed; Journal article, 2024)

  Objectives: The complexity of chronic pain requires interdisciplinary collaboration. Although this is recognisable in the framework for pain centres, few studies have investigated how interdisciplinary collaboration in ...

• Exploring the Discrepancy Between Subjective and Objective Measures of Executive Functions in Young Adult Survivors of Childhood Acute Lymphoblastic Leukemia 

  Egset, Kaja Solland; Weider, Siri; Hjemdal, Odin; Ruud, Ellen; Hjort, Magnus Aasved; Eilertsen, Mary-Elizabeth; Sund, Anne Mari; Stubberud, Jan Egil; Reinfjell, Trude (Peer reviewed; Journal article, 2024)

  Purpose: Childhood acute lymphoblastic leukemia (ALL) is associated with executive dysfunction in long-term survivorship. This is evidenced by subjective and objective measures of executive functions (EFs). However, the ...

• Oppfølgingen ved ensidig hodepine med autonome symptomer kan bli bedre 

  Hagen, Knut; Winsvold, Bendik Kristoffer Slagsvold; Bjørk, Marte-Helene; Tronvik, Erling Andreas; Bratterud, Laila Bratterud; Ofte, Hilde Karen; Lundqvist, Christofer; Sønnervik, Julie; Bäcklund, Nina (Peer reviewed; Journal article, 2024)

• Mortality from external causes in late adolescence and early adulthood by gestational age and sex: a population-based cohort study in four Nordic countries 

  Bilsteen, Josephine Funck; Opdahl, Signe; Pulakka, Anna; Finseth, Per Ivar; Yin, Weiyao; Pape, Kristine; Schei, Jorun; Metsälä, Johanna; Andersen, Anne-Marie Nybo; Sandin, Sven; Kajantie, Eero Olavi; Risnes, Kari (Journal article; Peer reviewed, 2024)

  Background: External causes of death, such as accidents, substance use, and suicide, contribute substantially to mortality during adolescence and early adulthood and show marked sex differences. Individuals born preterm ...

• Beyond the diagnosis of drug-resistant Tuberculosis in Norway: patients’ experiences before, during and after treatment 

  Storvig, Eline; Harstad, Ingunn; Ehrnström, Anna Greta Birgitta; Iversen, Valentina Maria Do Rosario Cab (Journal article; Peer reviewed, 2024)

  Background: This study aims to explore the varied experiences of patients with drug-resistant tuberculosis in Norway. The study emphasizes challenges and implications of being diagnosed with drug-resistant tuberculosis, ...

• Pasienter med forgiftning vurdert ved akuttmottaket på St. Olavs hospital 2019–20 

  Graabak, Gustav; Næss, Lars Eide; Laugsand, Lars Erik; Bjørnsen, Lars Petter Bache-Wiig (Journal article; Peer reviewed, 2024)

  Bakgrunn: Akutt forgiftning er en vanlig akuttmedisinsk problemstilling, men det mangler oppdaterte studier om insidens og forekomst av ulike giftstoffer fra norske akuttmottak. Formålet med denne studien var å kartlegge ...

• Spatial transcriptomics reveals strong association between SFRP4 and extracellular matrix remodeling in prostate cancer 

  Andersen, Maria K.; Krossa, Sebastian; Midtbust, Elise; Pedersen, Christine Aaserød; Wess, Maximilian; Høiem, Therese Stork; Viset, Trond; Størkersen, Øystein; Nervik, Ingunn; Sandsmark, Elise; Bertilsson, Helena Maria; Giskeødegård, Guro F.; Rye, Morten Beck; Tessem, May-Britt (Journal article; Peer reviewed, 2024)

  Prostate tumor heterogeneity is a major obstacle when studying the biological mechanisms of molecular markers. Increased gene expression levels of secreted frizzled-related protein 4 (SFRP4) is a biomarker in aggressive ...

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