St. Olavs hospital
Recent Submissions
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Left Ventricular Systolic Function in Long-Term Survivors of Allogeneic Hematopoietic Stem Cell Transplantation
(Peer reviewed; Journal article, 2020)Background Allogeneic hematopoietic stem cell transplantation (allo-HSCT), a potentially curative therapy for malignant and nonmalignant diseases, is being increasingly used in younger patients. Although allo-HSCT survivors ... -
Impact of different methods defining post-stroke neurocognitive disorder: The Nor-COAST study
(Peer reviewed; Journal article, 2020)Introduction Post‐stroke neurocognitive disorder (NCD) is common; prevalence varies between studies, partially related to lack of consensus on how to identify cases. The aim was to compare the prevalence of post‐stroke ... -
Mitigating adolescent social anxiety symptoms: the effects of social support and social self-efficacy in findings from the Young-HUNT 3 study
(Peer reviewed; Journal article, 2020)Adolescents’ exposure to negative life events (NLEs) and potentially traumatic events is highly prevalent and increases their risk of developing psychological disorders considerably. NLE exposure has also been linked to ... -
Incidence of invasive Group B Streptococcal infection and the risk of infant death and cerebral palsy: a Norwegian Cohort Study
(Peer reviewed; Journal article, 2020)Background Group B Streptococcus (GBS) is the leading cause of invasive neonatal infection worldwide. In high-income countries mortality rates are 4–10%, and among survivors of GBS meningitis 30–50% have neurodevelopmental ... -
Discrimination of Breast Cancer from Healthy Breast Tissue Using a Three-component Diffusion-weighted MRI Model
(Peer reviewed; Journal article, 2020)Purpose: Diffusion-weighted MRI (DW-MRI) is a contrast-free modality that has demonstrated ability to discriminate between predefined benign and malignant breast lesions. However, how well DW-MRI discriminates cancer from ... -
Cerebrospinal fluid sTREM2 in Alzheimer’s disease: comparisons between clinical presentation and AT classification
(Peer reviewed; Journal article, 2020)Triggering receptor expressed on myeloid cells 2 (TREM2) is an innate immune receptor expressed by microglia. Its cleaved fragments, soluble TREM2 (sTREM2), can be measured in the cerebrospinal fluid (CSF). Previous studies ... -
Mer fysikalsk behandling og mindre kirurgi for pasienter med skuldersmerte. Virkningen av behandlingen, kunnskapshullene og veien videre.
(Peer reviewed; Journal article, 2020)Innledning: Skuldersmerte er en vanlig og ofte langvarig muskelskjelettplage. Subakromial smerte utgjør den klart største diagnostiske gruppen. I nye faglige retningslinjer frarådes den mest vanlige formen for skulderkirurgi; ... -
Longterm Outcomes of Temporomandibular Joints in Juvenile Idiopathic Arthritis: 17 Years of Followup of a Nordic Juvenile Idiopathic Arthritis Cohort.
(Peer reviewed; Journal article, 2020)Objective. To determine the prevalence of orofacial symptoms, dysfunctions, and deformities of the temporomandibular joint (TMJ) in juvenile idiopathic arthritis (JIA) 17 years after disease onset. Methods. Drawn from ... -
Identification of novel genetic variants associated with cardiorespiratory fitness
(Peer reviewed; Journal article, 2020)Introduction Low maximal oxygen uptake (VO2max) is a strong and independent risk factor for all-cause and cardiovascular disease (CVD) mortality. For other CVD risk factors, numerous genetic association studies have been ... -
Genetic interaction between the non‐homologous end joining factors during B and T lymphocyte development: in vivo mouse models
(Peer reviewed; Journal article, 2020)Non-homologous end joining (NHEJ) is the main DNA repair mechanism for the repair of double-strand breaks (DSBs) throughout the course of the cell cycle. DSBs are generated in developing B and T lymphocytes during V(D)J ... -
Early gut fungal and bacterial microbiota and childhood growth
(Peer reviewed; Journal article, 2020)Introduction: Childhood growth is a sensitive marker of health. Animal studies show increased height and weight velocity in the presence of fungal as well as antibiotic supplement in feed. Human studies on early gut ... -
Dietary changes in early-stage breast cancer patients from pre-surgery and over the 12 months post-surgery
(Peer reviewed; Journal article, 2020)The time after a breast cancer diagnosis is a potential period for making positive dietary changes, but previous results are conflicting. The main aim of the present study was to study breast cancer patients’ dietary changes ... -
Developmental Course and Risk Factors of Physical Aggression in Late Adolescence
(Peer reviewed; Journal article, 2020)This study examined risk factors of physical aggression during transition from early to late adolescence using a two-wave longitudinal study. Specifically, we examined if risk factors in early adolescence predict physically ... -
Developing Cognition Endpoints for the CENTER-TBI Neuropsychological Test Battery
(Peer reviewed; Journal article, 2020)Background: Measuring cognitive functioning is common in traumatic brain injury (TBI) research, but no universally accepted method for combining several neuropsychological test scores into composite, or summary, scores ... -
The complex genetic landscape of familial MDS and AML reveals pathogenic germline variants
(Peer reviewed; Journal article, 2020)The inclusion of familial myeloid malignancies as a separate disease entity in the revised WHO classification has renewed efforts to improve the recognition and management of this group of at risk individuals. Here we ... -
Surgery for Extraforaminal Lumbar Disc Herniation: A Single Center Comparative Observational Study
(Peer reviewed; Journal article, 2020)Background Surgery on extraforaminal lumbar disc herniation (ELDH) is a commonly performed procedure. Operating on this type of herniation is known to come with more difficulties than on the frequently seen paramedian ... -
Surgery for herniated lumbar disc in private vs public hospitals: A pragmatic comparative effectiveness study
(Peer reviewed; Journal article, 2020)Background There is limited evidence on the comparative performance of private and public healthcare. Our aim was to compare outcomes following surgery for lumbar disc herniation (LDH) in private versus public hospitals. ... -
Comparison of methods to construct a genetic risk score for prediction of rheumatoid arthritis in the population-based Nord-Trøndelag Health Study, Norway
(Peer reviewed; Journal article, 2020)Objectives: To evaluate selection methods among published single-nucleotide polymorphisms (SNPs) associated with RA to construct predictive genetic risk scores (GRSs) in a population-based setting. Methods: The Nord-Trøndelag ... -
A high cerebrospinal fluid soluble TREM2 level is associated with slow clinical progression of Alzheimer's disease
(Peer reviewed; Journal article, 2020)Introduction: The progression rate of Alzheimer's disease (AD) varies and might be affected by the triggering receptor expressed on myeloid cells (TREM2) activity. We explored if cerebrospinal fluid (CSF) soluble TREM2 ... -
Pediatric Patients in a Local Nepali Emergency Department: Presenting Complaints, Triage and Post-Discharge Mortality
(Peer reviewed; Journal article, 2020)Background. In low-income countries, pediatric emergency care is largely underdeveloped although child mortality in emergency care is more than twice that of adults, and mortality after discharge is high. Aim. We aimed at ...