Now showing items 662-681 of 1110

    • Nanobody-directed targeting of optogenetic tools to study signaling in the primary cilium 

      Hansen, Jan; Kaiser, Fabian; Klausen, Christina; Stüven, Birthe; Chong, Raymond; Bönigk, Wolfgang; Mick, David; Möglich, Andreas; Jurisch-Yaksi, Nathalie; Schmidt, Florian; Wachten, Dagmar (Peer reviewed; Journal article, 2020)
      Compartmentalization of cellular signaling forms the molecular basis of cellular behavior. The primary cilium constitutes a subcellular compartment that orchestrates signal transduction independent from the cell body. ...
    • The Natural Course of Chronic Pain in a General Population: Stability and Change in an Eight-Wave Longitudinal Study Over Four Years (the HUNT Pain Study). 

      Glette, Mari; Stiles, Tore C; Borchgrevink, Petter Chr.; Landmark, Tormod (Peer reviewed; Journal article, 2020)
      Epidemiological studies have to a little extent addressed the potential fluctuations of chronic pain over time, and there is a lack of information about the long-term course of pain using repeated measurements. We wanted ...
    • A needs assessment of resuscitative endovascular balloon occlusion of the aorta (REBOA) in non-traumatic out-of-hospital cardiac arrest in Norway 

      Brede, Jostein Rødseth; Kramer-Johansen, Jo; Rehn, Marius (Peer reviewed; Journal article, 2020)
      Introduction: Out of hospital cardiac arrest (OHCA) carries an 86% mortality rate in Norway. Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a potential adjunct in management of non-traumatic cardiac ...
    • NeoDoppler: New ultrasound technology for continous cerebral circulation monitoring in neonates. 

      Vik, Sigrid Dannheim; Torp, Hans; Follestad, Turid; Støen, Ragnhild; Nyrnes, Siri Ann (Journal article; Peer reviewed, 2019)
      BACKGROUND: There is a strong need for continuous cerebral circulation monitoring in neonatal care, since suboptimal cerebral blood flow may lead to brain injuries in preterm infants and other critically ill neonates. ...
    • Nephronectin as a matrix effector in cancer 

      Norvoll Magnussen, Synnøve; Toraskar, Jimita Prashant; Hadler-Olsen, Elin Synnøve; Steigedal, Tonje S.; Svineng, Gunbjørg (Peer reviewed; Journal article, 2021)
      The extracellular matrix protein nephronectin plays an important regulatory role during embryonic development, controlling renal organogenesis through integrin α8β1 association. Nephronectin has three main domains: five ...
    • Neural networks for parameter estimation in microstructural MRI: application to a diffusion-relaxation model of white matter 

      de Almeida Martins, João Pedro; Nilsson, Markus; Lampinen, Björn; Palombo, Marco; While, Peter Thomas; Westin, Carl-Fredrik; Szczepankiewicz, Filip (Peer reviewed; Journal article, 2021)
      Specific features of white matter microstructure can be investigated by using biophysical models to interpret relaxation-diffusion MRI brain data. Although more intricate models have the potential to reveal more details ...
    • Neural signaling modulates metabolism of gastric cancer 

      Rabben, Hanne-Line; Andersen, Gøran Troseth; Olsen, Magnus Kringstad; Øverby, Anders; Ianevski, Aleksandr; Kainov, Denis; Wang, Timothy Cragin; Lundgren, Steinar; Grønbech, Jon Erik; Chen, Duan; Zhao, Chun-Mei (Peer reviewed; Journal article, 2021)
      Tumors comprise cancer cells and the associated stromal and immune/inflammatory cells, i.e., tumor microenvironment (TME). Here, we identify a metabolic signature of human and mouse model of gastric cancer and show that ...
    • Neurocognitive Outcome and Compensating Possibilities in Children and Adolescents Treated for Acute Lymphoblastic Leukemia With Chemotherapy Only 

      Lofstad, Grete Elisabeth; Reinfjell, Trude; Weider, Siri; Diseth, Trond H; Hestad, Knut (Journal article; Peer reviewed, 2019)
      Aim: To examine the neurocognitive outcomes in children and adolescents with acute lymphoblastic leukemia (ALL) in remission who were treated with systemic chemotherapy only (CTO). Methods: Neurocognitive performances ...
    • Neuromodulatory effect of NLRP3 and ASC in neonatal hypoxic ischemic encephalopathy 

      Ystgaard, Martin Bogale; Scheffler, Katja; Suganthan, Rajikala; Bjørås, Magnar; Ranheim, Trine; Sagen, Ellen Lund; Halvorsen, Bente; Saugstad, Ola Didrik; Yndestad, Arne (Journal article; Peer reviewed, 2019)
      Background: Following birth asphyxia there is a robust inflammatory response. NLRP3 is a receptor of the innate immune system. Upon activation, NLRP3 forms an inflammasome together with ASC and procaspase-1 to mediate ...
    • Neuropsychological functions of verbal recall and psychomotor speed significantly affect pain tolerance 

      Jacobsen, Henrik Børsting; Stubhaug, Audun; Schirmer, Henrik; Landrø, Nils Inge; Wilsgaard, Tom; Mathiesen, Ellisiv B.; Nielsen, Christopher Sivert (Peer reviewed; Journal article, 2019)
      Background: Effects from cognitive performance on pain tolerance have been documented, however, sample sizes are small and confounders often overlooked. We aimed to establish that performance on neuropsychological tests ...
    • Neurosurgical treatment and outcome patterns of meningioma in Sweden: a nationwide registry-based study 

      Corell, Alba; Thurin, Erik; Skoglund, Thomas; Farahmand, Dan; Henriksson, Roger; Rydenhag, Bertil; Gulati, Sasha; Bártek, Jiří; Jakola, Asgeir Store (Peer reviewed; Journal article, 2019)
      Background Surgery is the main treatment modality for intracranial meningiomas, but data on short-term surgical outcome are limited. The aim of this Swedish nationwide registry-based study was to benchmark the 30-day ...
    • Neurotoxic effects of mercury exposure in dental personnel 

      Bjørklund, Geir; Hilt, Bjørn; Dadar, Maryam; Lindh, U; Aaseth, Jan (Peer reviewed; Journal article, 2019)
      Numerous studies have reported neurobehavioural effects in dental personnel occupationally exposed to chronic low levels of mercury (Hg). Hg exposure from dental work may also induce various chronic conditions such as ...
    • "Never in my mind to give up!" A qualitative study of long-term intensive care patients' inner strength and willpower-Promoting and challenging aspects 

      Alexandersen, Ingeborg; Stjern, Berit; Eide, Regina; Haugdahl, Hege Selnes; Paulsby, Tove Engan; Lund, Stine Borgen; Haugan, Gørill (Journal article; Peer reviewed, 2019)
      Aims and objectives To explore aspects that promote and challenge long‐term ICU patients’ inner strength and willpower. Background Considerable research has been devoted to ICU patients’ experiences; however, research ...
    • New reference intervals for cortisol, cortisol binding globulin and free cortisol index in women using ethinyl estradiol 

      Panton, Kristine Kollerøs; Mikkelsen, Gustav; Irgens, Wenche Elna Øiestad; Hovde, Ann Kristin; Killingmo, Marte Wien; Øien, Monja Airin; Thorsby, Per Medbøe; Åsberg, Arne (Peer reviewed; Journal article, 2019)
      Healthy women using contraceptives containing a low dose of an estrogen may have a higher serum concentration of cortisol (s-cortisol) and cortisol binding globulin (s-CBG) than the commonly used upper reference limits. ...
    • A new removable airway stent 

      Amundsen, Tore; Sørhaug, Sveinung; Leira, Håkon Olav; Tyvold, Stig Sverre; Langø, Thomas; Hammer, Tommy Arild; Manstad-Hulaas, Frode; Mattsson, Erney (Peer reviewed; Journal article, 2016)
      Background Malignant airway obstruction is a feared complication and will most probably occur more frequently in the future because of increasing cancer incidence and increased life expectancy in cancer patients. Minimal ...
    • New-onset pain in the early phase and three months following stroke – data from a multicenter study 

      Bovim, Martina Reiten; Indredavik, Bent; Hokstad, Anne; Lydersen, Stian; Askim, Torunn (Journal article; Peer reviewed, 2018)
      Background: The reported prevalence of pain after stroke varies considerably, depending on how pain is measured, time after stroke, and characteristics of the selected population. The aims of this study were to investigate ...
    • NICU dialects: Understanding Norwegian practice variation 

      Syltern, Janicke Marita; Markestad, Trond Jacob; Saugstad, Ola Didrik; Støen, Ragnhild (Journal article; Peer reviewed, 2018)
      In Norway, a national consensus-based guideline used to address thresholds for offering life support at extreme preterm birth was issued in 1998. Since then, therapeutic advances may have changed attitudes and expectations ...
    • NMR spectroscopy of human eye tissues: A new insight into ocular biochemistry 

      Kryczka, Tomasz Aleksander; Wylegala, E; Dobrowolski, D; Midelfart, Anna (Journal article; Peer reviewed, 2014)
      Background. The human eye is a complex organ whose anatomy and functions has been described very well to date. Unfortunately, the knowledge of the biochemistry and metabolic properties of eye tissues varies. Our objective ...
    • Non-coding RNAs in human breast milk: A systematic review 

      Tingö, Lina; Ahlberg, Emelie; Johansson, Lovisa; Pedersen, Sindre Andre; Chawla, Konika; Sætrom, Pål; Cione, Erika; Simpson, Melanie Rae (Peer reviewed; Journal article, 2021)
      Breast milk is the primary source of nutrition and hydration for the newborn infant but also plays an important role in the child’s first immune defense. Additionally, several breast milk factors have been implicated in ...
    • Non-communicable diseases at a regional hospital in Nepal: Findings of a high burden of alcohol-related disease 

      Amundsen, Marie S.; Kirkeby, Tine Marita Gjervan; Giri, Samita; Koju, R; Krishna, SS; Ystgaard, Brynjulf; Solligård, Erik; Risnes, Kari (Peer reviewed; Journal article, 2016)
      Recent global burden of disease reports find that a major proportion of global deaths and disability worldwide can be attributed to alcohol use. Thus, it may be surprising that very few studies have reported on the burden ...