Now showing items 506-525 of 869

    • Nanobody-directed targeting of optogenetic tools to study signaling in the primary cilium 

      Hansen, Jan; Kaiser, Fabian; Klausen, Christina; Stüven, Birthe; Chong, Raymond; Bönigk, Wolfgang; Mick, David; Möglich, Andreas; Jurisch-Yaksi, Nathalie; Schmidt, Florian; Wachten, Dagmar (Peer reviewed; Journal article, 2020)
      Compartmentalization of cellular signaling forms the molecular basis of cellular behavior. The primary cilium constitutes a subcellular compartment that orchestrates signal transduction independent from the cell body. ...
    • A needs assessment of resuscitative endovascular balloon occlusion of the aorta (REBOA) in non-traumatic out-of-hospital cardiac arrest in Norway 

      Brede, Jostein Rødseth; Kramer-Johansen, Jo; Rehn, Marius (Peer reviewed; Journal article, 2020)
      Introduction: Out of hospital cardiac arrest (OHCA) carries an 86% mortality rate in Norway. Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a potential adjunct in management of non-traumatic cardiac ...
    • NeoDoppler: New ultrasound technology for continous cerebral circulation monitoring in neonates. 

      Vik, Sigrid Dannheim; Torp, Hans; Follestad, Turid; Støen, Ragnhild; Nyrnes, Siri Ann (Journal article; Peer reviewed, 2019)
      BACKGROUND: There is a strong need for continuous cerebral circulation monitoring in neonatal care, since suboptimal cerebral blood flow may lead to brain injuries in preterm infants and other critically ill neonates. ...
    • Nephronectin as a matrix effector in cancer 

      Norvoll Magnussen, Synnøve; Toraskar, Jimita Prashant; Hadler-Olsen, Elin Synnøve; Steigedal, Tonje S.; Svineng, Gunbjørg (Peer reviewed; Journal article, 2021)
      The extracellular matrix protein nephronectin plays an important regulatory role during embryonic development, controlling renal organogenesis through integrin α8β1 association. Nephronectin has three main domains: five ...
    • Neural signaling modulates metabolism of gastric cancer 

      Rabben, Hanne-Line; Andersen, Gøran Troseth; Olsen, Magnus Kringstad; Øverby, Anders; Ianevski, Aleksandr; Kainov, Denis; Wang, Timothy Cragin; Lundgren, Steinar; Grønbech, Jon Erik; Chen, Duan; Zhao, Chun-Mei (Peer reviewed; Journal article, 2021)
      Tumors comprise cancer cells and the associated stromal and immune/inflammatory cells, i.e., tumor microenvironment (TME). Here, we identify a metabolic signature of human and mouse model of gastric cancer and show that ...
    • Neurocognitive Outcome and Compensating Possibilities in Children and Adolescents Treated for Acute Lymphoblastic Leukemia With Chemotherapy Only 

      Lofstad, Grete Elisabeth; Reinfjell, Trude; Weider, Siri; Diseth, Trond H; Hestad, Knut (Journal article; Peer reviewed, 2019)
      Aim: To examine the neurocognitive outcomes in children and adolescents with acute lymphoblastic leukemia (ALL) in remission who were treated with systemic chemotherapy only (CTO). Methods: Neurocognitive performances ...
    • Neuromodulatory effect of NLRP3 and ASC in neonatal hypoxic ischemic encephalopathy 

      Ystgaard, Martin Bogale; Scheffler, Katja; Suganthan, Rajikala; Bjørås, Magnar; Ranheim, Trine; Sagen, Ellen Lund; Halvorsen, Bente; Saugstad, Ola Didrik; Yndestad, Arne (Journal article; Peer reviewed, 2019)
      Background: Following birth asphyxia there is a robust inflammatory response. NLRP3 is a receptor of the innate immune system. Upon activation, NLRP3 forms an inflammasome together with ASC and procaspase-1 to mediate ...
    • Neurosurgical treatment and outcome patterns of meningioma in Sweden: a nationwide registry-based study 

      Corell, Alba; Thurin, Erik; Skoglund, Thomas; Farahmand, Dan; Henriksson, Roger; Rydenhag, Bertil; Gulati, Sasha; Bártek, Jiří; Jakola, Asgeir Store (Peer reviewed; Journal article, 2019)
      Background Surgery is the main treatment modality for intracranial meningiomas, but data on short-term surgical outcome are limited. The aim of this Swedish nationwide registry-based study was to benchmark the 30-day ...
    • "Never in my mind to give up!" A qualitative study of long-term intensive care patients' inner strength and willpower-Promoting and challenging aspects 

      Alexandersen, Ingeborg; Stjern, Berit; Eide, Regina; Haugdahl, Hege Selnes; Paulsby, Tove Engan; Lund, Stine Borgen; Haugan, Gørill (Journal article; Peer reviewed, 2019)
      Aims and objectives To explore aspects that promote and challenge long‐term ICU patients’ inner strength and willpower. Background Considerable research has been devoted to ICU patients’ experiences; however, research ...
    • New reference intervals for cortisol, cortisol binding globulin and free cortisol index in women using ethinyl estradiol 

      Panton, Kristine Kollerøs; Mikkelsen, Gustav; Irgens, Wenche Elna Øiestad; Hovde, Ann Kristin; Killingmo, Marte Wien; Øien, Monja Airin; Thorsby, Per Medbøe; Åsberg, Arne (Peer reviewed; Journal article, 2019)
      Healthy women using contraceptives containing a low dose of an estrogen may have a higher serum concentration of cortisol (s-cortisol) and cortisol binding globulin (s-CBG) than the commonly used upper reference limits. ...
    • A new removable airway stent 

      Amundsen, Tore; Sørhaug, Sveinung; Leira, Håkon Olav; Tyvold, Stig Sverre; Langø, Thomas; Hammer, Tommy Arild; Manstad-Hulaas, Frode; Mattsson, Erney (Peer reviewed; Journal article, 2016)
      Background Malignant airway obstruction is a feared complication and will most probably occur more frequently in the future because of increasing cancer incidence and increased life expectancy in cancer patients. Minimal ...
    • New-onset pain in the early phase and three months following stroke – data from a multicenter study 

      Bovim, Martina Reiten; Indredavik, Bent; Hokstad, Anne; Lydersen, Stian; Askim, Torunn (Journal article; Peer reviewed, 2018)
      Background: The reported prevalence of pain after stroke varies considerably, depending on how pain is measured, time after stroke, and characteristics of the selected population. The aims of this study were to investigate ...
    • NICU dialects: Understanding Norwegian practice variation 

      Syltern, Janicke Marita; Markestad, Trond Jacob; Saugstad, Ola Didrik; Støen, Ragnhild (Journal article; Peer reviewed, 2018)
      In Norway, a national consensus-based guideline used to address thresholds for offering life support at extreme preterm birth was issued in 1998. Since then, therapeutic advances may have changed attitudes and expectations ...
    • NMR spectroscopy of human eye tissues: A new insight into ocular biochemistry 

      Kryczka, Tomasz Aleksander; Wylegala, E; Dobrowolski, D; Midelfart, Anna (Journal article; Peer reviewed, 2014)
      Background. The human eye is a complex organ whose anatomy and functions has been described very well to date. Unfortunately, the knowledge of the biochemistry and metabolic properties of eye tissues varies. Our objective ...
    • Non-communicable diseases at a regional hospital in Nepal: Findings of a high burden of alcohol-related disease 

      Amundsen, Marie S.; Kirkeby, Tine Marita Gjervan; Giri, Samita; Koju, R; Krishna, SS; Ystgaard, Brynjulf; Solligård, Erik; Risnes, Kari (Peer reviewed; Journal article, 2016)
      Recent global burden of disease reports find that a major proportion of global deaths and disability worldwide can be attributed to alcohol use. Thus, it may be surprising that very few studies have reported on the burden ...
    • Non-disclosure of suicidal ideation in psychiatric inpatients: Rates and correlates 

      Høyen, Karina Sagmo; Solem, Stian; Cohen, Lisa Janet; Prestmo, Astrid; Hjemdal, Odin; Vaaler, Arne; Galynker, Igor; Torgersen, Terje (Peer reviewed; Journal article, 2021)
      The study explored how common non-disclosure of suicidal ideation is in a sample of adult psychiatric inpatients (N = 171) plus associated patient characteristics. A large percentage (51.5%) withheld some information on ...
    • Nonfatal occupational injuries in norwegian Farmers 

      Svendsen, Kristin V Hirsch; Aas, Oddfrid; Hilt, Bjørn (Journal article; Peer reviewed, 2014)
      Background Agriculture ranks among the most dangerous trades worldwide. There is, however, still a lack of knowledge on nonfatal injuries in agriculture. The aim of this study was to describe the nature and occurrence of ...
    • Nonsupine positioning after macular hole surgery: A prospective multicenter study 

      Lindtjørn, Birger; Krohn, Jørgen Gitlesen; Austeng, Dordi; Fossen, Kristian; Varhaug, Pål; Basit, Samy; Helgesen, Ole Harald; Eide, Geir Egil; Forsaa, Vegard Asgeir (Journal article; Peer reviewed, 2019)
      Purpose To evaluate the postoperative closure rate of full-thickness macular holes (MHs) after nonsupine positioning, which means that the patients avoid upward gaze and a supine sleeping position, and to investigate the ...
    • Norwegian constraint-induced therapy multisite trial: Adherence to treatment protocol applied early after stroke 

      Stock, Roland; Thrane, Gyrd; Askim, Torunn; Karlsen, Gunn Marte; Langørgen, Eli; Erichsen, Anne Spendrup; Gjone, Ragna Ingeborg; Anke, Audny (Peer reviewed; Journal article, 2015)
      Objective: To investigate to what degree patients adhered to a modified constraint-induced movement therapy protocol, and to explore factors associated with the results. Design: Prospective follow-up of the intervention ...
    • Norwegian obstetricians' experiences of the use of ultrasound in pregnancy management. A qualitative study 

      Edvardsson, Kristina; Åhman, Annika; Fagerli, Tove Anita; Darj, Elisabeth; Holmlund, Sofia; Small, Rhonda; Mogren, Ingrid (Peer reviewed; Journal article, 2017)
      Objective To explore obstetricians’ experiences and views of the use of obstetric ultrasound in clinical management of pregnancy. Methods A qualitative interview study was undertaken in 2015 with obstetricians (N = 20) ...