• Serotonin—A Driver of Progressive Heart Valve Disease 

      Waldum, Helge; Wahba, Alexander (Peer reviewed; Journal article, 2022)
      It is well known that some serotoninergic drugs and neuroendocrine tumors producing serotonin (5-HT) may induce valvular heart disease by stimulation of proliferation of valvular cells via interaction with a 5-HT receptor ...
    • Serum 25-hydroxyvitamin D levels and risk of lung cancer and histologic types: a Mendelian randomization analysis of the HUNT study 

      Sun, Yi-Qian; Brumpton, Ben Michael; Bonilla, Carolina; Lewis, Sarah J.; Burgess, Stephen; Skorpen, Frank; Chen, Yue; Nilsen, Tom Ivar Lund; Romundstad, Pål Richard; Mai, Xiao-Mei (Journal article; Peer reviewed, 2018)
      We aimed to investigate potential causal associations between serum 25-hydroxyvitamin D [25(OH)D] levels and incidence of lung cancer overall and histologic types. We performed a Mendelian randomization (MR) analysis using ...
    • Serum and urine concentrations of morphine and morphine metabolites in patients with advanced cancer receiving continuous intravenous morphine: An observational study Cancer palliative care 

      Lee, Yong Joo; Suh, Sang-Yeon; Song, Junghan; Lee, Sanghee Shiny; Seo, Ah-Ram; Ahn, Hong-Yup; Lee, Myung Ah; Kim, Chul-Min; Klepstad, Pål (Peer reviewed; Journal article, 2015)
      Background:The feasibility and clinical implication of drug monitoring of morphine, morphine-6-glucuronide (M6G)and morphine-3-glucuronide (M3G) need further investigation. This study aimed to determine what predicts ...
    • Serum Concentrations of Selected Poly- and Perfluoroalkyl Substances (PFASs) in Pregnant Women and Associations with Birth Outcomes. A Cross-Sectional Study from Southern Malawi 

      Mwapasa, Mphatso; Huber, Sandra; Chakhame, Bertha Immaculate; Maluwa, Alfred; Odland, Maria Lisa; Röllin, Halina; Choko, Augustine; Xu, Shanshan; Odland, Jon Øyvind (Journal article; Peer reviewed, 2023)
      Pervasive exposure to per-and polyfluoroalkyl substances (PFASs) shows associations with adverse pregnancy outcomes. The aim of the present study was to examine the determinants of different serum PFAS concentrations in ...
    • Serum lipoprotein(a) is not modified by interleukin-6 receptor antagonism or associated with inflammation in non-ST-elevation myocardial infarction 

      Ueland, Thor; Kleveland, Ola; Michelsen, Annika; Wiseth, Rune; Damås, Jan Kristian; Holven, Kirsten Bjørklund; Aukrust, Pål; Gullestad, Lars; Yndestad, Arne; Halvorsen, Bente (Journal article; Peer reviewed, 2018)
      Background The IL-6 receptor antagonist tocilizumab has been shown to attenuate the proatherogenic lipoprotein a [Lp(a)] in rheumatoid arthritis. We evaluated if a single dose of tocilizumab reduced Lp(a) in patients with ...
    • Serum metabolome associated with severity of acute traumatic brain injury 

      Thomas, Ilias; Dickens, Alex M.; Posti, Jussi P.; Czeiter, Endre; Duberg, Daniel; Sinioja, Tim; Kråkström, Matilda; Retel Helmrich, Isabel R. A.; Wang, Kevin K. W.; Maas, Andrew I. R.; Steyerberg, Ewout W.; Menon, David K.; Tenovuo, Olli; Hyötyläinen, Tuulia; Büki, András; Orešič, Matej; Åkerlund, Cecilia; Amrein, Krisztina; Andelic, Nada; Andreassen, Lasse; Anke, Audny Gabriele Wagner; Antoni, Anna; Audibert, Gérard; Azouvi, Philippe; Azzolini, Maria Luisa; Bartels, Ronald; Barzó, Pál; Beauvais, Romuald; Beer, Ronny; Bellander, Bo-Michael; Belli, Antonio; Benali, Habib; Berardino, Maurizio; Beretta, Luigi; Blaabjerg, Morten; Bragge, Peter; Brazinova, Alexandra; Brinck, Vibeke; Brooker, Joanne; Brorsson, Camilla; Bullinger, Monika; Cabeleira, Manuel; Caccioppola, Alessio; Calappi, Emiliana; Calvi, Maria Rosa; Cameron, Peter; Lozano, Guillermo Carbayo; Carbonara, Marco; Cavallo, Simona; Chevallard, Giorgio; Chieregato, Arturo; Citerio, Giuseppe; Clusmann, Hans; Coburn, Mark; Coles, Jonathan; Cooper, Jamie D.; Correia, Marta; Čović, Amra; Curry, Nicola; Czeiter, Endre; Czosnyka, Marek; Dahyot-Fizelier, Claire; Dark, Paul; Dawes, Helen; De Keyser, Véronique; Degos, Vincent; Corte, Francesco Della; den Boogert, Hugo; Depreitere, Bart; Đilvesi, Đula; Dixit, Abhishek; Donoghue, Emma; Dreier, Jens; Dulière, Guy-Loup; Ercole, Ari; Esser, Patrick; Ezer, Erzsébet; Fabricius, Martin; Feigin, Valery L.; Foks, Kelly; Frisvold, Shirin; Furmanov, Alex; Gagliardo, Pablo; Galanaud, Damien; Gantner, Dashiell; Gao, Guoyi; George, Pradeep; Ghuysen, Alexandre; Giga, Lelde; Glocker, Ben; Golubovic, Jagoš; Gomez, Pedro A.; Gratz, Johannes; Gravesteijn, Benjamin; Grossi, Francesca; Gruen, Russell L.; Gupta, Deepak; Haagsma, Juanita A.; Haitsma, Iain; Helbok, Raimund; Helseth, Eirik; Horton, Lindsay; Huijben, Jilske; Hutchinson, Peter J.; Jacobs, Bram; Jankowski, Stefan; Jarrett, Mike; Jiang, Ji-yao; Johnson, Faye; Jones, Kelly; Karan, Mladen; Kolias, Angelos G.; Kompanje, Erwin; Kondziella, Daniel; Kornaropoulos, Evgenios; Koskinen, Lars-Owe; Kovács, Noémi; Kowark, Ana; Lagares, Alfonso; Lanyon, Linda; Laureys, Steven; Lecky, Fiona; Ledoux, Didier; Lefering, Rolf; Legrand, Valerie; Lejeune, Aurelie; Levi, Leon; Lightfoot, Roger; Lingsma, Hester; Maas, Andrew I. R.; Castaño-León, Ana M.; Maegele, Marc; Majdan, Marek; Manara, Alex; Manley, Geoffrey; Martino, Costanza; Maréchal, Hugues; Mattern, Julia; McMahon, Catherine; Melegh, Béla; Menovsky, Tomas; Mikolic, Ana; Misset, Benoit; Muraleedharan, Visakh; Murray, Lynnette; Negru, Ancuta; Nelson, David; Newcombe, Virginia; Nieboer, Daan; Nyirádi, József; Olubukola, Otesile; Ortolano, Fabrizio; Palotie, Aarno; Parizel, Paul M.; Payen, Jean-François; Perera, Natascha; Perlbarg, Vincent; Persona, Paolo; Peul, Wilco; Piippo-Karjalainen, Anna; Pirinen, Matti; Ples, Horia; Polinder, Suzanne; Pomposo, Inigo; Posti, Jussi P.; Puybasset, Louis; Radoi, Andreea; Ragauskas, Arminas; Raj, Rahul; Rambadagalla, Malinka; Rhodes, Jonathan; Richardson, Sylvia; Richter, Sophie; Ripatti, Samuli; Rocka, Saulius; Røe, Cecilie; Røise, Olav; Rosand, Jonathan; Rosenfeld, Jeffrey V.; Rosenlund, Christina; Rosenthal, Guy; Rossaint, Rolf; Rossi, Sandra; Rueckert, Daniel; Rusnák, Martin; Sahuquillo, Juan; Sakowitz, Oliver; Sanchez-Porras, Renan; Sandor, Janos; Schäfer, Nadine; Schmidt, Silke; Schoechl, Herbert; Schoonman, Guus; Schou, Rico Frederik; Schwendenwein, Elisabeth; Sewalt, Charlie; Skandsen, Toril; Smielewski, Peter; Sorinola, Abayomi; Stamatakis, Emmanuel; Stanworth, Simon; Stevens, Robert; Stewart, William; Stocchetti, Nino; Sundström, Nina; Takala, Riikka; Tamás, Viktória; Tamosuitis, Tomas; Taylor, Mark Steven; Te Ao, Braden; Theadom, Alice; Thomas, Matt; Tibboel, Dick; Timmers, Marjolein; Tolias, Christos; Trapani, Tony; Tudora, Cristina Maria; Unterberg, Andreas; Vajkoczy, Peter; Vallance, Shirley; Valeinis, Egils; Vámos, Zoltán; van der Jagt, Mathieu; Van der Steen, Gregory; van der Naalt, Joukje; van Dijck, Jeroen T. J. M.; van Essen, Thomas A.; Van Hecke, Wim; van Heugten, Caroline; Van Praag, Dominique; Vyvere, Thijs Vande; van Wijk, Roel P. J.; Vargiolu, Alessia; Vega, Emmanuel; Velt, Kimberley; Verheyden, Jan; Vespa, Paul M.; Vik, Anne; Vilcinis, Rimantas; Volovici, Victor; von Steinbüchel, Nicole; Voormolen, Daphne; Vulekovic, Petar; Wiegers, Eveline; Williams, Guy; Wilson, Lindsay; Winzeck, Stefan; Wolf, Stefan; Yang, Zhihui; Ylén, Peter; Younsi, Alexander; Zeiler, Frederick A.; Zelinkova, Veronika; Ziverte, Agate; Zoerle, Tommaso (Peer reviewed; Journal article, 2022)
      Complex metabolic disruption is a crucial aspect of the pathophysiology of traumatic brain injury (TBI). Associations between this and systemic metabolism and their potential prognostic value are poorly understood. Here, ...
    • Serum neurofilament as a predictor of 10-year grey matter atrophy and clinical disability in multiple sclerosis: a longitudinal study 

      Lie, Ingrid Anne; Kacar, Sezgi; Wesnes, Kristin; Brouwer, Iman; Kvistad, Silje S.; Wergeland, Stig; Holmøy, Trygve; Midgard, Rune; Bru, Alla Nikolajevna S; Edland, Astrid; Eikeland, Randi; Gosal, Sonia; Harbo, Hanne-Cathrin Flinstad; Kleveland, Grethe; Sørenes, Yvonne; Øksendal, Nina; Varhaug, Kristin Nielsen; Vedeler, Christian Alexander; Barkhof, Frederik; Teunissen, Charlotte E.; Bø, Lars; Torkildsen, Øivind Fredvik Grytten; Myhr, Kjell-Morten; Vrenken, Hugo (Peer reviewed; Journal article, 2022)
      Background - The predictive value of serum neurofilament light chain (sNfL) on long-term prognosis in multiple sclerosis (MS) is still unclear. Objective - Investigate the relation between sNfL levels over a 2-year period ...
    • Serum NMR-Based Metabolomics Profiling Identifies Lipoprotein Subfraction Variables and Amino Acid Reshuffling in Myeloma Development and Progression 

      Pedersen, Shona; Mikkelstrup, Morten Faarbæk; Kristensen, Søren Risom; Anwardeen, Najeha Rizwana; Elrayess, Mohamed A.; Andreassen, Trygve (Peer reviewed; Journal article, 2023)
      Multiple myeloma (MM) is an incurable hematological cancer. It is preceded by monoclonal gammopathy of uncertain significance (MGUS)—an asymptomatic phase. It has been demonstrated that early detection increases the 5-year ...
    • Serum or Plasma for Quantification of Direct Oral Anticoagulants? 

      Aakerøy, Rachel; Stokes, Charlotte Lorentze; Tomic, Marija; Hegstad, Solfrid; Kristoffersen, Ann-Helen; Ellekjær, Hanne; Schjøtt, Jan Didrik; Spigset, Olav; Helland, Arne (Peer reviewed; Journal article, 2022)
      Background: Direct oral anticoagulants are increasingly replacing vitamin K antagonists for prevention of stroke in patients with atrial fibrillation, partly owing to the lack of a need for routine monitoring. Therapeutic ...
    • Serumkonsentrasjonsmåling av gentamicin hos barn 

      Grodås, Karolina Teresa Maulen; Døllner, Henrik; Thaulow, Christian Magnus; Knudsen, Per Kristian; Tønnessen, Anders; Skeibrok, Mari; Klingenberg, Claus Andreas (Peer reviewed; Journal article, 2023)
      BAKGRUNN Gentamicin brukes ofte ved alvorlige infeksjoner hos barn. Det har værtrutine i Norge å måle serumkonsentrasjon av gentamicin re før andre ellertredje dose (0-prøve) for å vurdere risiko fortoksisitet. Den ...
    • Serumkonsentrasjonsmåling av gentamicin hos barn 

      Grodås, Karolina Teresa Maulen; Døllner, Henrik; Thaulow, Christian Magnus; Knudsen, Per Kristian; Tønnessen, Anders; Skeibrok, Mari; Klingenberg, Claus Andreas (Peer reviewed; Journal article, 2023)
      BAKGRUNN Gentamicin brukes ofte ved alvorlige infeksjoner hos barn. Det har vært rutine i Norge å måle serumkonsentrasjon av gentamicin rett før andre eller tredje dose (0-prøve) for å vurdere risiko for toksisitet. Den ...
    • Severe bradycardia and hypotension in anaesthetized pigs: Possible interaction between octreotide, xylazine, and atropine: A case series 

      Åm, Marte Kierulf; Teigen, Ingrid Anna; Carlsen, Sven Magnus; Christiansen, Sverre Christian (Peer reviewed; Journal article, 2023)
      Pigs are common animal models in diabetes research. Streptozotocin-induced destruction of pancreatic β-cells is used to induce diabetes in conscious pigs. However, in short-term non-recovery experiments, suppression of ...
    • Severe traumatic brain injury in Norway: impact of age on outcome 

      Røe, Cecilie; Skandsen, Toril; Anke, Audny; Ader, Tiina; Vik, Anne; Lund, Stine Borgen; Manskow, Unn Sollid; Sollid, Snorre; Sundstrøm, Terje; Hestnes, Morten; Andelic, Nada (Journal article; Peer reviewed, 2013)
      Objective: The aim of this study was to investigate the influence of age on mortality and 3-month outcome in a Norwegian cohort of patients with severe traumatic brain injury (TBI). Methods: Norwegian residents ≥ 16 years ...
    • Sex as a Moderator Between Parent Ratings of Executive Dysfunction and Social Difficulties in Children and Adolescents with Autism Spectrum Disorder 

      Torske, Tonje; Nærland, Terje; Quintana, Daniel; Hypher, Ruth Elizabeth; Kaale, Anett; Høyland, Anne Lise; Hope, Sigrun; Johannessen, Tor Jarle; Øie, Merete Glenne; Andreassen, Ole (Peer reviewed; Journal article, 2022)
      Girls and boys might differ in autistic symptoms and associated cognitive difficulties such as executive function (EF). We investigated sex differences in the relationship between parent rated EF and autistic symptoms in ...
    • Sex Differences and Similarities in Risk Factors of Physical Aggression in Adolescence 

      Henriksen, Marit; Skrove, Marit Synnøve; Hoftun, Gry Børmark; Lydersen, Stian; Stover, Carla; Kalvin, Carla B.; Sukhodolsky, Denis G. (Peer reviewed; Journal article, 2022)
      Considerable research has documented risk factors of physical aggression in adolescence. However, less is known of sex differences in these associations. The current study addressed this important area by examining sex ...
    • Sex hormones and sperm parameters after adjuvant oxaliplatin-based treatment for colorectal cancer 

      Falk, Philip; Severin, Mira; Berglund, Åke; Guren, Marianne; Hofsli, Eva; Österlund, Pia; Tandberg, Anne; Eberhard, Jakob; Sorbye, Halfdan (Peer reviewed; Journal article, 2022)
      Background The incidence of colorectal cancer (CRC) in individuals of fertile age is increasing. Oxaliplatin is a cornerstone treatment in the adjuvant setting for stage III and high-risk stage II CRC. Limited data exist ...
    • Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders 

      Blokland, Gabriella A. M.; Grove, Jakob; Chen, Chia-Yen; Cotsapas, Chris; Tobet, Stuart; Handa, Robert; St Clair, David; Lencz, Todd; Mowry, Bryan J.; Periyasamy, Sathish; Tooney, Paul A.; Kelly, Brian; Kirov, George; Sullivan, Patrick F.; Corvin, Aiden; Riley, Brien P.; Esko, Tonu; Milani, Lili; Palotie, Aarno; Ehrenreich, Hannelore; Sham, Pak C.; Iwata, Nakao; Weinberger, Daniel R.; Gejman, Pablo V.; Sanders, Alan R.; Buxbaum, Joseph D.; Rujescu, Dan; Giegling, Ina; Konte, Bettina; Hartmann, Annette M.; Bramon, Elvira; Murray, Robin M.; Pato, Michele T.; Lee, Jimmy; Melle, Ingrid; Molden, Espen; Ophoff, Roel A.; McQuillin, Andrew; Adolfsson, Rolf; Martin, Nicholas G.; Fullerton, Janice M.; Mitchell, Philip B.; Schofield, Peter R.; Forstner, Andreas J.; Degenhardt, Franziska; Comes, Ashley L.; Smeland, Olav Bjerkehagen; Vaaler, Arne; Andreassen, Ole; Jönsson, Erik Gunnar (Peer reviewed; Journal article, 2021)
      Background Sex differences in incidence and/or presentation of schizophrenia (SCZ), major depressive disorder (MDD), and bipolar disorder (BIP) are pervasive. Previous evidence for shared genetic risk and sex differences ...
    • Sex-specific associations of matrix metalloproteinases in Alzheimer’s disease 

      Aksnes, Mari; Edwin, Trine Holt; Saltvedt, Ingvild Tina; Eldholm, Rannveig Sakshaug; Chaudhry, Farrukh Abbas; Halaas, Nathalie Bodd; Myrstad, Marius; Watne, Leiv; Knapskog, Anne Brita (Peer reviewed; Journal article, 2023)
      Introduction Alzheimer’s disease (AD) can be characterised in vivo by biomarkers reflecting amyloid-β (Aβ) and tau pathology. However, there is a need for biomarkers reflecting additional pathological pathways. Matrix ...
    • Sexual function in long-term male lymphoma survivors after high-dose therapy with autologous stem-cell transplantation 

      Bersvendsen, Hanne Skjerven; Haugnes, Hege Sagstuen; Dahl, Alv A; Fagerli, Unn-Merete; Fluge, Øystein; Holte, Harald; Seland, Mette; Wilsgaard, Tom; Smeland, Knut Bjøro; Kiserud, Cecilie E. (Journal article; Peer reviewed, 2019)
      Reduced sexual function may have negative implications on health related quality of life among lymphoma survivors. A national cross-sectional study among long-term lymphoma survivors after high-dose therapy with autologous ...
    • Sexual functioning, sexual enjoyment, and body image in Norwegian breast cancer survivors: a 12-year longitudinal follow-up study and comparison with the general female population 

      Åsberg, Ragnhild Emilie; Giskeødegård, Guro F.; Raj, Sunil Xavier; Karlsen, Jarle; Engstrøm, Monica Jernberg; Salvesen, Øyvind Olav; Nilsen, Marianne; Lundgren, Steinar; Reidunsdatter, Randi Johansen (Peer reviewed; Journal article, 2023)
      Background Given the scarcity of evidence concerning the long-term sexual health of breast cancer (BC) survivors (BC-Pop), we aimed to assess how BC treatments affect short- and long-term sexual functioning, sexual ...