Browsing St. Olavs hospital by Title
Now showing items 1849-1868 of 2447
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Protein tyrosine phosphatases in multiple myeloma
(Peer reviewed; Journal article, 2020)Many cell signaling pathways are activated or deactivated by protein tyrosine phosphorylation and dephosphorylation, catalyzed by protein tyrosine kinases (PTKs) and protein tyrosine phosphatases (PTPs), respectively. Even ... -
Proteome alterations associated with transformation of multiple myeloma to secondary plasma cell leukemia
(Peer reviewed; Journal article, 2017)Plasma cell leukemia is a rare and aggressive plasma cell neoplasm that may either originate de novo (primary PCL) or by leukemic transformation of multiple myeloma (MM) to secondary PCL (sPCL). The prognosis of sPCL is ... -
Proteome-wide Mendelian randomization in global biobank meta-analysis reveals multi-ancestry drug targets for common diseases
(Peer reviewed; Journal article, 2022)Proteome-wide Mendelian randomization (MR) shows value in prioritizing drug targets in Europeans but with limited evidence in other ancestries. Here, we present a multi-ancestry proteome-wide MR analysis based on ... -
Prothrombotic genotypes and risk of venous thromboembolism in occult cancer
(Peer reviewed; Journal article, 2021)Background Studies have reported that the combination of some prothrombotic genotypes and overt cancer yields a synergistic effect on VTE risk. Whether individual prothrombotic genotypes or number of risk alleles in a ... -
A protocol for the development and validation of a virtual reality-based clinical test of social cognition
(Peer reviewed; Journal article, 2023)Background Impairments in social cognition are common after traumatic brain injury (TBI) and may have severe negative consequences for patients and their families. Most tests of social cognition have limited ecological ... -
Protocol of a randomised, controlled trial comparing immediate curative therapy with conservative treatment in men aged ≥75 years with non-metastatic high-risk prostate cancer (SPCG 19/GRand-P)
(Peer reviewed; Journal article, 2024)Background Older men (aged ≥75 years) with high risk, non-metastatic prostate cancer (PCa) are increasingly treated with curative therapy (surgery or radiotherapy). However, it is unclear if curative therapy prolongs ... -
Proton pump inhibitors and fracture risk. The HUNT study, Norway.
(Journal article; Peer reviewed, 2019)Summary Proton pump inhibitors (PPIs) have been linked to increased risk of fracture; the data have, however, been diverging. We did not find any increased risk of fractures among users of PPIs in a Norwegian population ... -
Providing quality data in health care - Almost perfect inter-rater agreement in the Norwegian tonsil surgery register
(Journal article; Peer reviewed, 2019)Background The Norwegian Tonsil Surgery Register (NTSR) was launched in January 2017. The purpose of the register is to present data on tonsil surgery to facilitate improvements in patient care. Data used for evaluating ... -
Pseudo-T2 mapping for normalization of T2-weighted prostate MRI
(Peer reviewed; Journal article, 2022)Objective Signal intensity normalization is necessary to reduce heterogeneity in T2-weighted (T2W) magnetic resonance imaging (MRI) for quantitative analysis of multicenter data. AutoRef is an automated dual-reference ... -
Psoriatic arthritis disease activity during and after pregnancy: A prospective multicenter study
(Journal article; Peer reviewed, 2019)Objective To study disease activity in women with peripheral psoriatic arthritis (PsA) during and after pregnancy. Previous knowledge on this topic is sparse. Methods The study included 108 pregnancies in 103 women with ... -
Psychiatric comorbidity in relation to clinical characteristics of epilepsy: A retrospective observational study
(Peer reviewed; Journal article, 2023)Purpose Prevalence of psychiatric disorders in people with epilepsy is high. However, diagnostic validity and information about the nature of the seizure disorders are often poor in population-based studies. In a well ... -
Psychoeducational Groups versus Waitlist in Treatment of Attention-Deficit Hyperactivity/Impulsivity Disorder (ADHD) in Adults: A Protocol for a Pilot Randomized Waitlist-Controlled Multicenter Trial.
(Journal article; Peer reviewed, 2019)Background Psychoeducation is included in the Norwegian national guidelines for treatment of adult ADHD. Despite some promising results for the treatment of other conditions and ADHD, little is known about the efficacy ... -
Psychometric properties of the Brief Problem Monitor (BPM) in children with internalizing symptoms: examining baseline data from a national randomized controlled intervention study
(Peer reviewed; Journal article, 2021)Background Prevention is essential to reduce the development of symptomology among children and adolescents into disorders, thereby improving public health and reducing costs. Therefore, easily administered screening and ... -
Psychometric properties of the Inventory of Life Quality in children and adolescents in Norwegian Sign Language
(Peer reviewed; Journal article, 2021)Background Several studies have assessed the Quality of Life (QoL) in Deaf and hard-of-hearing (DHH) children and adolescents. The findings from these studies, however, vary from DHH children reporting lower QoL than their ... -
Psychometric properties of the norwegian version of the electronic health literacy scale (eheals) among patients after percutaneous coronary intervention: Cross-sectional validation study
(Peer reviewed; Journal article, 2020)Background:Web-based technology has recently become an important source for sharing health information with patients after an acute cardiac event. Therefore, consideration of patients’ perceived electronic health (eHealth) ... -
Psychometric properties of the person-centred coordinated care experience questionnaire (P3CEQ) in a Norwegian radiotherapy setting
(Peer reviewed; Journal article, 2022)The number of older adults with cancer is increasing. Radiotherapy is an important treatment modality for cancer and may cause side effects and distress. Patient-reported experience measures aim to measure patients’ ... -
Psychometric properties of the Weiss Functional Impairment Rating Scale parent and self-reports in a Norwegian clinical sample of adolescents treated for ADHD
(Peer reviewed; Journal article, 2020)Objective To analyze the psychometric properties of the Norwegian version of the Weiss Functional Impairment Rating Scale parent and self-reports (WFIRS-P and WFIRS-S) in adolescents with ADHD. Methods 102 clinically ... -
Psychometric Properties of the WHO-5 Well-Being Index among Nurses during the COVID-19 Pandemic: A Cross-Sectional Study in Three Countries
(Peer reviewed; Journal article, 2022)Nurses’ well-being has been increasingly recognised due to the ongoing pandemic. However, no validation scales measuring nurses’ well-being currently exist. Thus, we aimed to validate the WHO-5 Well-Being Index (WHO-5) in ... -
Psychopathy subdomains in violent offenders with and without a psychotic disorder
(Peer reviewed; Journal article, 2022)Background Violence in psychosis has been linked to antisocial behavior and psychopathy traits. Psychopathy comprises aspects of interpersonal, affective, lifestyle, and antisocial traits which may be differently involved ... -
Psychotropic and anti-epileptic drug use, before and after surgery, among patients with low-grade glioma: a nationwide matched cohort study
(Journal article; Peer reviewed, 2021)Background: Low-grade glioma (LGG) is a relatively rare type of brain tumour. The use of antidepressant, sedative and anti-epileptic drugs can reflect the burden of the disease. While epilepsy is well-described in patients ...