• The prognostic value of pre-treatment circulating biomarkers of systemic inflammation (CRP, dNLR, YKL-40, and IL-6) in vulnerable older patients with metastatic colorectal cancer receiving palliative chemotherapy—The Randomized NORDIC9-Study 

      Liposits, Gabor; Skuladottir, Halla; Ryg, Jesper; Winther, Stine Brændegaard; Möller, Sören; Hofsli, Eva; Shah, Carl-Henrik; Poulsen, Laurids Østergaard; Berglund, Åke; Qvortrup, Camilla; Osterlund, Pia; Johansen, Julia S.; Glimelius, Bengt; Sorbye, Halfdan; Pfeiffer, Per (Peer reviewed; Journal article, 2022)
      Appropriate patient selection for palliative chemotherapy is crucial in patients with metastatic colorectal cancer (mCRC). We investigated the prognostic value of C-reactive protein (CRP), derived neutrophil-to-lymphocyte ...
    • Progressive multifocal leukoencephalopathy in an immunocompetent patient? 

      Johansen, Krisztina; Torp, Sverre Helge; Rydland, Jana; Aasly, Jan (Peer reviewed; Journal article, 2013)
      Background: Progressive multifocal leukoencephalopathy (PML) is a rapidly progressive, potentially fatal, demyelinating disease affecting immunosuppressed patients. PML is rarely reported in cases with no underlying disease ...
    • Prolonged migraine aura: New insights from a prospective diary-aided study 

      Viana, Michele; Sances, Grazia; Linde, Mattias; Nappi, Giuseppe; Khaliq, Farihah; Goadsby, Peter J.; Tassorelli, Cristina (Journal article; Peer reviewed, 2018)
      Background: There is limited literature on prolonged aura (PA - defined as an aura including at least one symptom for > 1 h and < 7d), and there are no prospective studies. The aim of this study is to characterize prospectively ...
    • Promoting coordination in Norwegian health care 

      Romøren, Tor Inge; Torjesen, Dag Olaf; Landmark, Brynjar Fowels (Journal article; Peer reviewed, 2011)
      Introduction: The Norwegian health care system is well organized within its two main sectors - primary health and long term care on the one hand, and hospitals and specialist services on the other. However, the relation ...
    • A prospective observational study comparing two supraglottic airway devices in out-of-hospital cardiac arrest 

      Lønvik, Maja Pålsdatter; Elden, Odd Erik; Lunde, Mats Joakimsen; Nordseth, Trond; Bakkelund, Karin Elvenes; Uleberg, Oddvar (Journal article; Peer reviewed, 2021)
      Background: Airway management in patients with out of hospital cardiac arrest (OHCA) is important and several methods are used. The establishment of a supraglottic airway device (SAD) is a common technique used during OHCA. ...
    • The prospective relation between eating behaviors and BMI from middle childhood to adolescence: A 5-wave community study 

      Bjørklund, Oda; Wichstrøm, Lars; Llewellyn, Clare; Steinsbekk, Silje (Peer reviewed; Journal article, 2022)
      Some eating behaviors are associated with increased risk of childhood obesity and are thus potential targets for obesity prevention. However, longitudinal research, especially on older children and adolescents, is needed ...
    • A prospective study of pulmonary outcomes and chest computed tomography in the first year after COVID-19 

      Lerum, Tøri Vigeland; Meltzer, Carin; Rivero, Jezabel Rodriguez; Aaløkken, Trond Mogens; Brønstad, Eivind; Aarli, Bernt Bøgvald; Lund, Kristine Marie Aarberg; Durheim, Michael Thomas; Ashraf, Haseem; Einvik, Gunnar; Skjønsberg, Ole Henning; Stavem, Knut (Peer reviewed; Journal article, 2023)
      COVID-19 primarily affects the respiratory system. We aimed to evaluate how pulmonary outcomes develop after COVID-19 by assessing participants from the first pandemic wave prospectively 3 and 12 months following hospital ...
    • Prospects of returning to work after lumbar spine surgery for patients considering disability pension: A nationwide study based on data from the Norwegian Registry for Spine Surgery 

      Hammer, Lovise; Ingebrigtsen, Tor; Gulati, Sasha; Hara, Sozaburo; Nygaard, Øystein Petter; Hara, Karen Walseth; Solberg, Tore (Peer reviewed; Journal article, 2023)
      Objectives To assess the odds for not returning to work (non-RTW) 1 year after treatment among patients who had applied for or were planning to apply for disability pension (DP-applicant) prior to an operation for degenerative ...
    • Protect us from ourselves: Balancing the parental instinct of saving 

      Ursin, Lars Øystein; Syltern, Janicke Marita (Peer reviewed; Journal article, 2019)
      Background: Neonatologists, legal experts and ethicists extensively discuss the ethical challenges of decision-making when a child is born at the limit of viability. The voices of parents are less heard in this discussion. ...
    • Protein tyrosine phosphatases in multiple myeloma 

      Abdollahi, Pegah; Köhn, Maja; Børset, Magne (Peer reviewed; Journal article, 2020)
      Many cell signaling pathways are activated or deactivated by protein tyrosine phosphorylation and dephosphorylation, catalyzed by protein tyrosine kinases (PTKs) and protein tyrosine phosphatases (PTPs), respectively. Even ...
    • Proteome alterations associated with transformation of multiple myeloma to secondary plasma cell leukemia 

      Zatula, Alexey; Dikic, Aida; Mulder, Teska Celine; Sharma, Animesh; Vågbø, Cathrine Broberg; Sousa, Mirta; Waage, Anders; Slupphaug, Geir (Peer reviewed; Journal article, 2017)
      Plasma cell leukemia is a rare and aggressive plasma cell neoplasm that may either originate de novo (primary PCL) or by leukemic transformation of multiple myeloma (MM) to secondary PCL (sPCL). The prognosis of sPCL is ...
    • Proteome-wide Mendelian randomization in global biobank meta-analysis reveals multi-ancestry drug targets for common diseases 

      Zhao, Huiling; Rasheed, Humaria; Nøst, Therese Haugdahl; Cho, Yoonsu; Liu, Yi; Bhatta, Laxmi; Bhattacharya, Arjun; Hemani, Gibran; Davey Smith, George; Brumpton, Ben Michael; Zhou, Wei; Neale, Benjamin M.; Gaunt, Tom R.; Zheng, Jie (Peer reviewed; Journal article, 2022)
      Proteome-wide Mendelian randomization (MR) shows value in prioritizing drug targets in Europeans but with limited evidence in other ancestries. Here, we present a multi-ancestry proteome-wide MR analysis based on ...
    • Prothrombotic genotypes and risk of venous thromboembolism in occult cancer 

      Skille, Hanne; Paulsen, Benedikte; Hveem, Kristian; Severinsen, Marianne T.; Gabrielsen, Maiken Elvestad; Kristensen, Søren R.; Næss, Inger Anne; Hindberg, Kristian; Tjønneland, Anne; Brækkan, Sigrid Kufaas; Hansen, John-Bjarne (Peer reviewed; Journal article, 2021)
      Background Studies have reported that the combination of some prothrombotic genotypes and overt cancer yields a synergistic effect on VTE risk. Whether individual prothrombotic genotypes or number of risk alleles in a ...
    • A protocol for the development and validation of a virtual reality-based clinical test of social cognition 

      Matre, Martin; Johansen, Truls Sveløkken; Olsen, Alexander; Tornås, Sveinung; Martinsen, Anne Catrine Trægde; Lund, Anne; Becker, Frank; Brunborg, Cathrine; Spikman, Joke; Ponsford, Jennie; Neumann, Dawn; McDonald, Skye; Løvstad, Marianne (Peer reviewed; Journal article, 2023)
      Background Impairments in social cognition are common after traumatic brain injury (TBI) and may have severe negative consequences for patients and their families. Most tests of social cognition have limited ecological ...
    • Protocol of a randomised, controlled trial comparing immediate curative therapy with conservative treatment in men aged ≥75 years with non-metastatic high-risk prostate cancer (SPCG 19/GRand-P) 

      Löffeler, Sven; Bertilsson, Helena Maria; Müller, Christoph Rainer; Aas, Kirsti; Haugnes, Hege Sagstuen; Aksnessæther, Bjørg Yksnøy; Pesonen, Maiju; Thon, Kristian; Tandstad, Torgrim; Murtola, Teemu; Poulsen, Mads Hvid Aaberg; Nordstrøm, Tobias; Vigmostad, Maria Nyre; Ottosson, Fredrik; Holmsten, Karin; Christiansen, Ola B.; Slaaen, Marit; Haug, Erik Skaaheim; Storås, Anne Holck; Asphaug, Lars; Rannikko, Antti; Brasso, Klaus (Peer reviewed; Journal article, 2024)
      Background Older men (aged ≥75 years) with high risk, non-metastatic prostate cancer (PCa) are increasingly treated with curative therapy (surgery or radiotherapy). However, it is unclear if curative therapy prolongs ...
    • Proton pump inhibitors and fracture risk. The HUNT study, Norway. 

      Hoff, Mari; Skovlund, Eva; Skurtveit, Svetlana; Meyer, Haakon E; Langhammer, Arnulf; Søgaard, Anne-Johanne; Syversen, Unni; Forsmo, Siri; Abrahamsen, Bo; Schei, Berit (Journal article; Peer reviewed, 2019)
      Summary Proton pump inhibitors (PPIs) have been linked to increased risk of fracture; the data have, however, been diverging. We did not find any increased risk of fractures among users of PPIs in a Norwegian population ...
    • Providing quality data in health care - Almost perfect inter-rater agreement in the Norwegian tonsil surgery register 

      Wennberg, Siri; Karlsen, Lasse A; Stalfors, Joacim; Bratt, Mette; Bugten, Vegard (Journal article; Peer reviewed, 2019)
      Background The Norwegian Tonsil Surgery Register (NTSR) was launched in January 2017. The purpose of the register is to present data on tonsil surgery to facilitate improvements in patient care. Data used for evaluating ...
    • Pseudo-T2 mapping for normalization of T2-weighted prostate MRI 

      Sørland, Kaia Ingerdatter; Sunoqrot, Mohammed R. S.; Sandsmark, Elise; Langørgen, Sverre; Bertilsson, Helena; Trimble, Christopher George; Lin, Gigin; Selnæs, Kirsten Margrete; Goa, Pål Erik; Bathen, Tone Frost; Elschot, Mattijs (Peer reviewed; Journal article, 2022)
      Objective Signal intensity normalization is necessary to reduce heterogeneity in T2-weighted (T2W) magnetic resonance imaging (MRI) for quantitative analysis of multicenter data. AutoRef is an automated dual-reference ...
    • Psoriatic arthritis disease activity during and after pregnancy: A prospective multicenter study 

      Ursin, Kristin; Lydersen, Stian; Skomsvoll, Johan Fredrik; Wallenius, Marianne (Journal article; Peer reviewed, 2019)
      Objective To study disease activity in women with peripheral psoriatic arthritis (PsA) during and after pregnancy. Previous knowledge on this topic is sparse. Methods The study included 108 pregnancies in 103 women with ...
    • Psychiatric comorbidity in relation to clinical characteristics of epilepsy: A retrospective observational study 

      Revdal, Eline; Kolstad, Bjørn Patrick; Winsvold, Bendik Kristoffer Slagsvold; Selmer, Kaja Kristine; Morken, Gunnar; Brodtkorb, Eylert (Peer reviewed; Journal article, 2023)
      Purpose Prevalence of psychiatric disorders in people with epilepsy is high. However, diagnostic validity and information about the nature of the seizure disorders are often poor in population-based studies. In a well ...