Browsing St. Olavs hospital by Title

Now showing items 1487-1506 of 2447

    • MutT homologue 1 (MTH1) removes N6-methyl-dATP from the dNTP pool 

      Scaletti, Emma Rose; Vallin, Karl S.A.; Bräutigam, Lars; Sarno, Antonio; Berglund, Ulrika Warpman; Helleday, Thomas; Stenmark, Pål; Jemth, Ann-Sofie (Peer reviewed; Journal article, 2020)
      MutT homologue 1 (MTH1) removes oxidized nucleotides from the nucleotide pool and thereby prevents their incorporation into the genome and thereby reduces genotoxicity. We previously reported that MTH1 is an efficient ...

    • My Health Sensor, my Classifier – Adapting a Trained Classifier to Unlabeled End-User Data 

      Nikolaidis, Konstantinos; Kristiansen, Stein; Plagemann, Thomas Peter; Goebel, Vera Hermine; Liestøl, Knut; Kankanhalli, Mohan; Traaen, Gunn Marit; Øverland, Britt; Akre, Harriet; Aakerøy, Lars; Steinshamn, Sigurd Loe (Peer reviewed; Journal article, 2022)
      Sleep apnea is a common yet severely under-diagnosed sleep related disorder. Unattended sleep monitoring at home with low-cost sensors can be leveraged for condition detection, and Machine Learning offers a generalized ...

    • My husband is not ill; He has memory loss - Caregivers perspectives on health care services for persons with dementia 

      Granbo, Randi; Boulton, Elisabeth; Saltvedt, Ingvild; Helbostad, Jorunn L.; Taraldsen, Kristin (Journal article; Peer reviewed, 2019)
      Background To explore informal caregivers’ perspectives and perceived needs related to health care services/activities for older adults with dementia, in order to understand barriers and facilitators to participation. The ...

    • Mycotic abdominal aortic aneurysm caused by Borrelia afzelii: a case report 

      Torsteinsen, Magne; Nilsen, Hans-Johnny; Damås, Jan Kristian; Stensvåg, Dordi; Nyrønning, Linn Ålstedt; Bergh, Kåre (Peer reviewed; Journal article, 2022)
      Background Inflammatory aneurysms and mycotic aneurysms make up a minority of abdominal aortic aneurysms. Mainly autoimmune mechanisms are proposed in the pathogenesis of inflammatory aneurysms, and it is not routine ...

    • Myeloma-derived extracellular vesicles mediate HGF/c-Met signaling in osteoblast-like cells 

      Strømme, Olaf; Psonka Antonczyk, Katarzyna Maria; Stokke, Bjørn Torger; Sundan, Anders; Arum, Carl-Jørgen; Brede, Gaute (Journal article; Peer reviewed, 2019)
      Multiple myeloma is an incurable cancer of antibody-producing plasma cells. Hepatocyte growth factor (HGF), a cytokine aberrantly expressed in half of myeloma patients, is involved in myeloma pathogenesis by enhancing ...

    • Nanobody-directed targeting of optogenetic tools to study signaling in the primary cilium 

      Hansen, Jan; Kaiser, Fabian; Klausen, Christina; Stüven, Birthe; Chong, Raymond; Bönigk, Wolfgang; Mick, David; Möglich, Andreas; Jurisch-Yaksi, Nathalie; Schmidt, Florian; Wachten, Dagmar (Peer reviewed; Journal article, 2020)
      Compartmentalization of cellular signaling forms the molecular basis of cellular behavior. The primary cilium constitutes a subcellular compartment that orchestrates signal transduction independent from the cell body. ...

    • Nasjonal anbefaling for utredning og behandling av døgnrytmelidelser 

      Bjorvatn, Bjørn; Kallestad, Håvard; Langsrud, Knut; Vedaa, Øystein; Pallesen, Ståle; Waage, Siri; Wilhelmsen-Langeland, Ane; Saxvig, Ingvild; Abeler, Karin Louise (Peer reviewed; Journal article, 2023)
      Nasjonal kompetansetjeneste for søvnsykdommer (fra 2023: Nasjonalt senter for søvnmedisin) nedsatte høsten 2022 en arbeidsgruppe for å utvikle en nasjonal anbefaling for utredning og behandling av døgnrytmelidelser. Gruppen ...

    • A national intercalated medical student research program–student perceptions, satisfaction, and factors associated with pursuing a PhD 

      Sandvei, Marie Søfteland; Jacobsen, Geir Wenberg; Stien, Marianne Heldal; Ræder, Helge; Munthe, Ludvig Andre; Skogen, Vegard (Peer reviewed; Journal article, 2022)
      Background To counteract a decreasing number of physician-scientists, a national intercalated Medical Student Research Programme (MSRP) was launched in Norway in 2002. We aimed to assess whether the students’ favourable ...

    • A nationwide study of patients operated for cervical degenerative disorders in public and private hospitals 

      Danielsen, Elisabeth; Mjåset, Christer; Ingebrigtsen, Tor; Gulati, Sasha; Grotle, Margreth; Rudolfsen, Jan Håkon; Nygaard, Øystein Petter; Solberg, Tore (Peer reviewed; Journal article, 2022)
      During the last decades, there has been an increase in the rate of surgery for degenerative disorders of the cervical spine and in the use of supplementary private health insurance. Still, there is limited knowledge about ...

    • Nationwide, population-based observational study of the molecular epidemiology and temporal trend of carbapenemase-producing Enterobacterales in Norway, 2015 to 2021 

      Ljungquist, Oskar; Haldorsen, Bjørg; Pöntinen, Anna Kaarina; Janice, Jessin; Josefsen, Ellen Haldis; Elstrøm, Petter; Kacelnik, Oliver; Sundsfjord, Arnfinn; Samuelsen, Ørjan; Handal, Nina; Ranheim, Trond Egil; Hansen, Bent-Are; Mjøen, Andreas Fossum; Lindemann, Paul Christoffer; Nilsen, Einar; Zaragkoulias, Kyriakos; Larsen, Hege Elisabeth; Bjørnholt, Jørgen; Gammelsrud, Karianne Wiger; Jakovljev, Aleksandra; Löhr, Iren Høyland; Bredberg, Anders; Marvik, Åshild; Minge, Christina; Tofteland, Ståle; Papp, Kristina; Onken, Annette; Weme, Einar Tollaksen; Guennigsman, Brian Albert (Peer reviewed; Journal article, 2023)
      National and regional carbapenemaseproducing Enterobacterales (CPE) surveillance is essential to understand the burden of antimicrobial resistance, elucidate outbreaks, and develop infection-control or antimicrobial-treatment ...

    • The Natural Course of Chronic Pain in a General Population: Stability and Change in an Eight-Wave Longitudinal Study Over Four Years (the HUNT Pain Study). 

      Glette, Mari; Stiles, Tore C; Borchgrevink, Petter Chr.; Landmark, Tormod (Peer reviewed; Journal article, 2020)
      Epidemiological studies have to a little extent addressed the potential fluctuations of chronic pain over time, and there is a lack of information about the long-term course of pain using repeated measurements. We wanted ...

    • Natural ingredient or nostalgic taste? Competing authenticities in the Norwegian vanilla tastescape 

      Plasil, Tanja; Stokland, Håkon B.; Cañás Bottos, Lorenzo (Peer reviewed; Journal article, 2022)
      Vanillin has been the main source of vanilla flavoring in products such as vanilla sugar, sauce and ice cream throughout the twentieth century, and hence the authentic taste Norwegians associated with vanilla. However, ...

    • A needs assessment of resuscitative endovascular balloon occlusion of the aorta (REBOA) in non-traumatic out-of-hospital cardiac arrest in Norway 

      Brede, Jostein Rødseth; Kramer-Johansen, Jo; Rehn, Marius (Peer reviewed; Journal article, 2020)
      Introduction: Out of hospital cardiac arrest (OHCA) carries an 86% mortality rate in Norway. Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a potential adjunct in management of non-traumatic cardiac ...

    • Needs assessment of resuscitative endovascular balloon occlusion of the aorta (REBOA) in patients with major haemorrhage: A cross-sectional study 

      Godø, Bård Neuenkirchen; Brede, Jostein Rodseth; Krüger, Andreas Jorstad (Peer reviewed; Journal article, 2021)
      Background Resuscitative endovascular balloon occlusion of the aorta (REBOA) can be used as an adjunct treatment in traumatic abdominopelvic haemorrhage, ruptured abdominal aortic aneurysms, postpartum haemorrhage (PPH), ...

    • NEFA Dynamics in Adults With Severe Obesity and Insulin Resistance: No Coupling to the rs9939609 FTO Risk Allele 

      Mostad, Ingrid Løvold; Grill, Valdemar Erik Robert (Peer reviewed; Journal article, 2023)
      Context: The FTO gene is highly expressed in adipose tissues; however, whether nonesterified fatty acids (NEFA) dynamics are impacted by FTO has not been rigorously tested for in a uniformly obese study population comprising ...

    • Negotiating scientific knowledge in the development of an eHealth MOOC 

      Gilstad, Heidi; Skogen, Martha Rice; Toussaint, Pieter Jelle; Larsen, Cathrin Brøndbo; Faxvaag, Arild (Peer reviewed; Journal article, 2022)
      Interdisciplinary team communication in eHealth development is challenging because all disciplines have unique, intrinsic discursive practices, theories and artefacts. Due to these factors, members of interdisciplinary ...

    • NEIL1 and NEIL2 DNA glycosylases modulate anxiety and learning in a cooperative manner in mice 

      Hildrestrand, Gunn Annette; Rolseth, Veslemøy; Kunath, Nicolas; Suganthan, Rajikala; Jensen, Vidar; Bugaj, Anna Maria; Fernandez Berrocal, Marion Silvana; SIkko, Sunniva Bøe; Vetlesen, Susanne; Kusnierczyk, Anna; Olsen, Ann-Karin Hardie; Gutzkow, Kristine Bjerve; Rowe, Alexander D.; Wang, Wei; Moldestad, Olve; Syrstad, Monika; Slupphaug, Geir; Eide, Lars; Klungland, Arne; Sætrom, Pål; Luna, Luisa; Ye, Jing; Scheffler, Katja; Bjørås, Magnar (Peer reviewed; Journal article, 2021)
      Oxidative DNA damage in the brain has been implicated in neurodegeneration and cognitive decline. DNA glycosylases initiate base excision repair (BER), the main pathway for oxidative DNA base lesion repair. NEIL1 and NEIL3 ...

    • Neoadjuvant Chemoradiotherapy and Surgery for Esophageal Squamous Cell Carcinoma Versus Definitive Chemoradiotherapy With Salvage Surgery as Needed: The Study Protocol for the Randomized Controlled NEEDS Trial 

      Nilsson, Magnus; Olafsdottir, Halla; Alexandersson von Döbeln, Gabriella; Villegas, Fernanda; Gagliardi, Giovanna; Hellström, Mats; Wang, Qiao-Li; Johansson, Hemming; Gebski, Val; Hedberg, Jakob; Klevebro, Fredrik; Markar, Sheraz; Smyth, Elizabeth; Lagergren, Pernilla; Al-Haidari, Ghazwan Ahmed Dhia Eldin; Rekstad, Lars Cato; Aahlin, Eirik Kjus; Wallner, Bengt; Edholm, David; Johansson, Jan; Szabo, Eva; Reynolds, John V.; Pramesh, C.S.; Mummudi, Naveen; Joshi, Amit; Ferri, Lorenzo; Wong, Rebecca KS; O’Callaghan, Chris; Lukovic, Jelena; Chan, Kelvin KW; Leong, Trevor; Barbour, Andrew; Smithers, Mark; Li, Yin; Kang, Xiaozheng; Kong, Feng-Ming; Chao, Yin-Kai; Crosby, Tom; Bruns, Christiane; van Laarhoven, Hanneke; van Berge Henegouwen, Mark; van Hillegersberg, Richard; Rosati, Riccardo; Piessen, Guillaume; de Manzoni, Giovanni; Lordick, Florian (Peer reviewed; Journal article, 2022)
      Background: The globally dominant treatment with curative intent for locally advanced esophageal squamous cell carcinoma (ESCC) is neoadjuvant chemoradiotherapy (nCRT) with subsequent esophagectomy. This multimodal treatment ...

    • Neoadjuvant chemotherapy versus neoadjuvant chemoradiotherapy for cancer of the esophagus or gastroesophageal junction: long-term results of a randomized clinical trial 

      von Döbeln, Gabriella Alexandersson; Klevebro, Fredrik; Jacobsen, Anne-Birgitte; Johannessen, Hans Olaf; Nielsen, Niels Hilmer; Johnsen, Gjermund; Hatlevoll, Ingunn; Glenjen, Nils; Friesland, Signe; Lundell, Lars R.; Yu, Jingru; Nilsson, Magnus (Peer reviewed; Journal article, 2019)
      NeoRes I is a randomized phase II trial comparing neoadjuvant chemoradiotherapy with neoadjuvant chemotherapy in the treatment of resectable cancer of the esophagus or gastroesophageal junction. Patients with biopsy-proven ...

    • NeoDoppler: New ultrasound technology for continous cerebral circulation monitoring in neonates. 

      Vik, Sigrid Dannheim; Torp, Hans; Follestad, Turid; Støen, Ragnhild; Nyrnes, Siri Ann (Journal article; Peer reviewed, 2019)
      BACKGROUND: There is a strong need for continuous cerebral circulation monitoring in neonatal care, since suboptimal cerebral blood flow may lead to brain injuries in preterm infants and other critically ill neonates. ...