Blar i St. Olavs hospital på tittel

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    • General movement optimality score and general movements trajectories following early parent-administrated physiotherapy in the neonatal intensive care unit 

      Ustad, Tordis; Fjørtoft, Toril Larsson; Øberg, Gunn Kristin (Peer reviewed; Journal article, 2021)
      Background The Prechtl General Movement Assessment (GMA) is a reliable tool for the functional assessment of the young nervous system. It is based on a global assessment of the quality of infants' movements. In addition, ...

    • General practitioners ending their practice and impact on patients' health, healthcare use and mortality: a protocol for national registry cohort studies in Norway, 2008 to 2021 

      Vinjerui, Kristin Hestmann; Anthun, Kjartan Sarheim; Asheim, Andreas; Carlsen, Fredrik; Mjølstad, Bente Prytz; Nilsen, Sara Marie; Pape, Kristine; Bjørngaard, Johan Håkon (Peer reviewed; Journal article, 2023)
      Introduction Continuous general practitioner (GP) and patient relations associate with positive health outcomes. Termination of GP practice is unavoidable, while consequences of final breaks in relations are less explored. ...

    • Generation of a Mouse Model Lacking the Non-Homologous End-Joining Factor Mri/Cyren 

      Castaneda Zegarra, Sergio Miguel; Huse, Camilla; Røsand, Øystein; Sarno, Antonio; Xing, Mengtan; Zhang, Qindong; Alirezaylavasani, Amin; Werner, Julia; Ji, Ping; Liabakk, Nina-Beate; Wang, Wei; Bjørås, Magnar; Oksenych, Valentyn (Journal article; Peer reviewed, 2019)
      Classical non-homologous end joining (NHEJ) is a molecular pathway that detects, processes, and ligates DNA double-strand breaks (DSBs) throughout the cell cycle. Mutations in several NHEJ genes result in neurological ...

    • The genes controlling normal function of citrate and spermine secretion are lost in aggressive prostate cancer and prostate model systems 

      Rye, Morten Beck; Krossa, Sebastian; Hall, Martina; van Mourik, Casper; Bathen, Tone Frost; Drabløs, Finn; Tessem, May-Britt; Bertilsson, Helena (Peer reviewed; Journal article, 2022)
      High secretion of the metabolites citrate and spermine is a unique hallmark for normal prostate epithelial cells, and is reduced in aggressive prostate cancer. However, the identity of the genes controlling this biological ...

    • Genetic architecture of subcortical brain structures in 38,851 individuals 

      Satizabal, Claudia L.; Adams, Hieab H.H.; Hibar, Derrek; White, Charles C.; Knol, Maria J.; Stein, Jason L.; Scholz, Markus; Sargurupremraj, Muralidharan; Jahanshad, Neda; Roshchupkin, Gennady V.; Smith, Albert V.; Bis, Joshua C.; Jian, Xueqiu; Luciano, Michelle; Hofer, Edith; Teumer, Alexander; van der Lee, Sven J.; Yang, Jingyun; Yanek, Lisa R.; Lee, Tom V.; Li, Shuo; Hu, Yanhui; Koh, Jia Yu; Eicher, John D.; Desrivières, Sylvane; Arias-Vasquez, Alejandro; Chauhan, Ganesh; Athanasiu, Lavinia; Rentería, Miguel E.; Kim, Sungeun; Hoehn, David; Armstrong, Nicola J.; Chen, Qiang; Holmes, Avram J.; den Braber, Anouk; Kloszewska, Iwona; Andersson, Micael; Espeseth, Thomas; Grimm, Oliver; Abramovic, Lucija; Alhusaini, Saud; Milaneschi, Yuri; Papmeyer, Martina; Axelsson, Tomas; Ehrlich, Stefan; Roiz-Santiáñez, Roberto; Kraemer, Bernd; Håberg, Asta; Jones, Hannah J; Pike, G. Bruce; Stein, Dan J.; Stevens, Allison; Bralten, Janita; Vernooij, Meike W.; Harris, Tamara B.; Filippi, Irina; Witte, A Veronica; Guadalupe, Tulio; Wittfeld, Katharina; Mosley, Thomas H.; Becker, James T.; Doan, Nhat Trung; Hagenaars, Saskia P.; Saba, Yasaman; Cuellar-Partida, Gabriel; Amin, Najaf; Hilal, Saima; Nho, Kwangsik; Mirza-Schreiber, Nazanin; Arfanakis, Konstantinos; Becker, Diane M.; Ames, David; Goldman, Aaron L.; Lee, Phil H.; Boomsma, Dorret I.; Lovestone, Simon; Giddaluru, Sudheer; Le Hellard, Stephanie; Mattheisen, Manuel; Bohlken, Marc M.; Kasperaviciute, Dalia; Schmaal, Lianne; Lawrie, Stephen M.; Agartz, Ingrid; Walton, Esther; Tordesillas-Gutierrez, Diana; Davies, Gareth E.; Shin, Jean; Ipser, Jonathan C.; Vinke, Louis N.; Hoogman, Martine; Jia, Tianye; Burkhardt, Ralph; Klein, Marieke; Crivello, Fabrice; Janowitz, Deborah; Carmichael, Owen; Haukvik, Unn Kristin H.; Aribisala, Benjamin S.; Schmidt, Helena; Strike, Lachlan T.; Cheng, Ching-Yu; Risacher, Shannon L.; Putz, Benno; Fleischman, Debra A.; Assareh, Amelia A.; Mattay, Venkata S.; Buckner, Randy L.; Mecocci, Patrizia; Dale, Anders; Cichon, Sven; Boks, Marco P.; Matarin, Mar; Penninx, Brenda W.J.H.; Calhoun, Vince D.; Chakravarty, M. Mallar; Marquand, André F.; Macare, Christine; Kharabian Masouleh, Shahrzad; Oosterlaan, Jaap; Amouyel, Philippe; Hegenscheid, Katrin; Rotter, Jerome I.; Schork, Andrew J.; Liewald, David C.M.; de Zubicaray, Greig I.; Wong, Tien Yin; Shen, Li; Sämann, Philipp G.; Brodaty, Henry; Roffman, Joshua L.; de Geus, Eco J.C.; Tsolaki, Magda; Erk, Susanne; van Eijk, Kristel R.; Cavalleri, Gianpiero L.; Van Der Wee, Nic J.A.; McIntosh, Andrew M.; Gollub, Randy L.; Bulayeva, Kazima B.; Bernard, Manon; Richards, Jennifer S.; Himali, Jayandra J.; Loeffler, Markus; Rommelse, Nanda; Hoffmann, Wolfgang; Westlye, Lars Tjelta; Valdés Hernández, Maria C.; Hansell, Narelle K.; van Erp, Theo G.M.; Wolf, Christiane; Kwok, John B.J.; Vellas, Bruno; Heinz, Andreas; Olde Loohuis, Loes M.; Delanty, Norman; Ho, Beng-Choon; Ching, Christopher R.K.; Shumskaya, Elena; Singh, Baljeet; Hofman, Albert; van der Meer, Dennis; Homuth, Georg; Psaty, Bruce M.; Bastin, Mark E.; Montgomery, Grant W.; Foroud, Tatiana M.; Reppermund, Simone; Hottenga, Jouke-Jan; Simmons, Andrew; Meyer-Lindenberg, Andreas; Cahn, Wiepke; Whelan, Christopher D; van Donkelaar, Marjolein M.J.; Yang, Qiong; Hosten, Norbert; Green, Robert C.; Thalamuthu, Anbupalam; Mohnke, Sebastian; Hulshoff Pol, Hilleke E.; Lin, Honghuang; Jack, Clifford R.; Schofield, Peter R.; Mühleisen, Thomas W.; Maillard, Pauline; Potkin, Steven G.; Wen, Wei; Fletcher, Evan; Toga, Arthur W.; Gruber, Oliver; Huentelman, Matthew; Davey Smith, George; Launer, Lenore J.; Nyberg, Lars; Jönsson, Erik Gunnar; Crespo-Facorro, Benedicto; Koen, Nastassja; Greve, Douglas N.; Uitterlinden, André G.; Weinberger, Daniel R.; Steen, Vidar Martin; Fedko, Iryna O.; Groenewold, Nynke A.; Niessen, Wiro J.; Toro, Roberto; Tzourio, Christophe; Longstreth, William T.; Ikram, M. Kamran; Smoller, Jordan W.; van Tol, Marie-Jose; Sussmann, Jessika E.; Paus, Tomáš; Lemaître, Hervé; Schroeter, Matthias L.; Mazoyer, Bernard; Andreassen, Ole Andreas; Holsboer, Florian; Depondt, Chantal; Veltman, Dick J.; Turner, Jessica A.; Pausova, Zdenka; Schumann, Gunter; van Rooij, Daan; Djurovic, Srdjan; Deary, Ian J.; McMahon, Katie L; Müller-Myhsok, Bertram; Brouwer, Rachel M.; Soininen, Hilkka; Pandolfo, Massimo; Wassink, Thomas H.; Cheung, Joshua W.; Wolfers, Thomas; Martinot, Jean-Luc; Zwiers, Marcel P.; Nauck, Matthias; Melle, Ingrid; Martin, Nicholas G.; Kanai, Ryota; Westman, Eric; Kahn, René S.; Sisodiya, Sanjay M.; White, Tonya; Saremi, Arvin; van Bokhoven, Hans; Brunner, Han G.; Völzke, Henry; Wright, Margaret J.; van `t Ent, Dennis; Nöthen, Markus M.; Ophoff, Roel A.; Buitelaar, Jan K.; Fernandéz, Guillén; Sachdev, Perminder S.; Rietschel, Marcella; van Haren, Neeltje E.M.; Fisher, Simon E.; Beiser, Alexa S.; Francks, Clyde; Saykin, Andrew J.; Mather, Karen A.; Romanczuk-Seiferth, Nina; Hartman, Catharina A.; DeStefano, Anita L; Heslenfeld, Dirk J.; Weiner, Michael W.; Walter, Henrik; Hoekstra, Pieter J.; Nyquist, Paul A.; Franke, Barbara; Bennett, David A.; Grabe, Hans J.; Johnson, Andrew D.; Chen, Christopher; van Duijn, Cornelia M.; Lopez, Oscar L.; Fornage, Myriam; Wardlaw, Joanna M.; Schmidt, Reinhold; DeCarli, Charles; De Jager, Philip L.; Villringer, Arno; Debette, Stéphanie; Gudnason, Vilmundur; Medland, Sarah E.; Shulman, Joshua M.; Thompson, Paul M.; Seshadri, Sudha; Ikram, M. Arfan (Journal article, 2019)
      Subcortical brain structures are integral to motion, consciousness, emotions and learning. We identified common genetic variation related to the volumes of the nucleus accumbens, amygdala, brainstem, caudate nucleus, globus ...

    • The genetic architecture of the human cerebral cortex 

      Grasby, Katrina L.; Jahanshad, Neda; Painter, Jodie N; Colodro-Conde, Lucía; Bralten, Janita; Agartz, Ingrid; Alnæs, Dag; Gurholt, Tiril Pedersen; Kaufmann, Tobias; Sønderby, Ida Elken; van der Meer, Dennis; Westlye, Lars Tjelta; Wolfers, Thomas; Djurovic, Srdjan; Le Hellard, Stephanie; Andreassen, Ole Andreas; Jönsson, Erik Gunnar; Steen, Vidar Martin; Medland, Sarah E. (Peer reviewed; Journal article, 2020)
      The cerebral cortex underlies our complex cognitive capabilities, yet little is known about the specific genetic loci that influence human cortical structure. To identify genetic variants that affect cortical structure, ...

    • Genetic associations with temporal shifts in obesity and severe obesity during the obesity epidemic in Norway: A longitudinal population-based cohort (the HUNT Study) 

      Brandkvist, Maria Charlotta; Bjørngaard, Johan Håkon; Ødegård, Rønnaug; Brumpton, Ben Michael; Smith, George Davey; Åsvold, Bjørn Olav; Sund, Erik; Kvaløy, Kirsti; Willer, Cristen J.; Vie, Gunnhild Åberge (Peer reviewed; Journal article, 2020)
      Background Obesity has tripled worldwide since 1975 as environments are becoming more obesogenic. Our study investigates how changes in population weight and obesity over time are associated with genetic predisposition ...

    • Genetic control of variability in subcortical and intracranial volumes 

      Còrdova Palomera, Aldo; van der Meer, Dennis; Kaufmann, Tobias; Bettella, Francesco; Wang, Yunpeng; Alnæs, Dag; Doan, Nhat Trung; Agartz, Ingrid; Bertolino, Alessandro; Buitelaar, Jan; Coynel, David; Djurovic, Srdjan; Dørum, Erlend Solberg; Espeseth, Thomas; Fazio, Leonardo; Franke, Barbara; Frei, Oleksandr; Håberg, Asta; Le Hellard, Stephanie; Jönsson, Erik Gunnar; Kolskår, Knut-Kristian; Lund, Martina Jonette; Moberget, Torgeir; Nordvik, Jan; Nyberg, Lars; Papassotiropoulos, Andreas; Pergola, Giulio; de Quervain, Dominique; Rampino, Antonio; Richard, Geneviève; Rokicki, Jaroslav; Sanders, Anne-Marthe; Schwarz, Emanuel; Smeland, Olav Bjerkehagen; Steen, Vidar Martin; Starrfelt, Jostein; Sønderby, Ida Elken; Ulrichsen, Kristine Moe; Andreassen, Ole Andreas; Westlye, Lars Tjelta (Peer reviewed; Journal article, 2020)
      Sensitivity to external demands is essential for adaptation to dynamic environments, but comes at the cost of increased risk of adverse outcomes when facing poor environmental conditions. Here, we apply a novel methodology ...

    • Genetic diversity of rotavirus strains circulating in Norway before and after the introduction of rotavirus vaccination in children 

      Gibory, Moustafa; Bruun, Tone; Flem, Elmira; Dembinski, Jennifer Lynn; Haltbakk, Ildri; Størdal, Ketil; Nordbø, Svein Arne; Jakobsen, Kirsti; Haarr, Elisebet; Leegaard, Truls Michael; Dudman, Susanne Gjeruldsen (Peer reviewed; Journal article, 2021)
      Globally, rotavirus (RV) is the leading cause of acute gastroenteritis (AGE) in young children under 5 years of age. Implementation of RV vaccination is expected to result in fewer cases of RV in the target population, but ...

    • Genetic epidemiology of amyotrophic lateral sclerosis in Norway - a 2-year population based study 

      Olsen, Cathrine Goberg; Busk, Øyvind Løvold; Aanjesen, Tori Navestad; Alstadhaug, Karl Bjørnar; Bjørnå, Ingrid Kristine; Braathen, Geir Julius; Breivik, Kristin Lif; Demic, Natasha; Flemmen, Heidi Øyen; Hallerstig, Erika; HogenEsch, Ineke; Holla, Øystein Lunde; Jøntvedt, Anne Berit; Kampman, Margitta T.; Kleveland, Grethe; Kvernmo, Helene Ballo; Ljøstad, Unn; Maniaol, Angelina; Morsund, Åse Hagen; Nakken, Ola; Novy, Camilla; Rekand, Tiina; Schlüter, Katrin Ruth; Schuler, Stephan; Tveten, Kristian; Tysnes, Ole-Bjørn; Holmøy, Trygve; Høyer, Helle (Peer reviewed; Journal article, 2022)
      Background: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that affects motor neurons. In Europe, disease-causing genetic variants have been identified in 40-70% of familial ALS patients and approximately ...

    • Genetic insight into sick sinus syndrome 

      Thorolfsdottir, Rosa B.; Sveinbjornsson, Gardar; Aegisdottir, Hildur M.; Benonisdottir, Stefania; Stefánsdóttir, Lilja; Ivarsdottir, Erna V.; Halldorsson, Gisli H.; Sigurdsson, Jon K.; Torp-Pedersen, Christian; Weeke, Peter E.; Brunak, Søren; Westergaard, David; Pedersen, Ole B.; Sorensen, Erik; Nielsen, Kaspar R.; Burgdorf, Kristoffer S.; Banasik, Karina; Brumpton, Ben Michael; Zhou, Wei; Oddsson, Asmundur; Tragante, Vinicius; Hjorleifsson, Kristjan E.; Davidsson, Olafur B.; Rajamani, Sridharan; Jonsson, Stefan; Torfason, Bjarni; Valgardsson, Atli S.; Thorgeirsson, Gudmundur; Frigge, Michael L.; Thorleifsson, Gudmar; Norddahl, Gudmundur L.; Helgadottir, Anna; Gretarsdotti, Solveig; Sulem, Patrick; Jonsdottir, Ingileif; Willer, Cristen J.; Hveem, Kristian; Bundgaard, Henning; Ullum, Henrik; Arnar, David O.; Thorsteinsdottir, Unnur; Gudbjartsson, Daniel F.; Holm, Hilma; Stefansson, Kari (Peer reviewed; Journal article, 2021)

    • Genetic interaction between the non‐homologous end joining factors during B and T lymphocyte development: in vivo mouse models 

      Castaneda Zegarra, Sergio Miguel; Fernandez Berrocal, Marion Silvana; Tkachev, Max; Yao, Rouan; Esnardo Upfold, Nikki Lyn; Oksenych, Valentyn (Peer reviewed; Journal article, 2020)
      Non-homologous end joining (NHEJ) is the main DNA repair mechanism for the repair of double-strand breaks (DSBs) throughout the course of the cell cycle. DSBs are generated in developing B and T lymphocytes during V(D)J ...

    • Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies 

      Gorski, Mathias; Rasheed, Humaira; Teumer, Alexander; Thomas, Laurent; Graham, Sarah E.; Sveinbjornsson, Gardar; Winkler, Thomas W.; Günther, Felix; Stark, Klaus J.; Chai, Jin-Fang; Tayo, Bamidele O.; Wuttke, Matthias; Li, Yong; Tin, Adrienne; Ahluwalia, Tarunveer S.; Ärnlöv, Johan; Åsvold, Bjørn Olav; Bakker, Stephan J.L.; Banas, Bernhard; Bansal, Nisha; Biggs, Mary L.; Biino, Ginevra; Böhnke, Michael; Boerwinkle, Eric; Bottinger, Erwin P.; Brenner, Hermann; Brumpton, Ben Michael; Carroll, Robert J.; Chaker, Layal; Chalmers, John; Chee, Miao-Li; Chee, Miao-Ling; Cheng, Ching-Yu; Chu, Audrey Y.; Ciullo, Marina; Cocca, Massimiliano; Cook, James P.; Coresh, Josef; Cusi, Daniele; de Borst, Martin H.; Degenhardt, Frauke; Eckardt, Kai-Uwe; Endlich, Karlhans; Evans, Michele K.; Feitosa, Mary F.; Franke, Andre; Freitag-Wolf, Sandra; Fuchsberger, Christian; Gampawar, Piyush; Gansevoort, Ron T.; Ghanbari, Mohsen; Ghasemi, Sahar; Giedraitis, Vilmantas; Gieger, Christian; Gudbjartsson, Daniel F.; Hallan, Stein; Hamet, Pavel; Hishida, Asahi; Ho, Kevin; Hofer, Edith; Holleczek, Bernd; Holm, Hilma; Hoppmann, Anselm; Horn, Katrin; Hutri-Kähönen, Nina; Hveem, Kristian; Hwang, Shih-Jen; Ikram, M. Arfan; Josyula, Navya Shilpa; Jung, Bettina; Kähönen, Mika; Karabegović, Irma; Khor, Chiea-Chuen; Koenig, Wolfgang; Kramer, Holly; Krämer, Bernhard K.; Kühnel, Brigitte; Kuusisto, Johanna; Laakso, Markku; Lange, Leslie A.; Lehtimäki, Terho; Li, Man; Lieb, Wolfgang; Lind, Lars; Lindgren, Cecilia M.; Loos, Ruth J.F.; Lukas, Mary Ann; Lyytikäinen, Leo-Pekka; Mahajan, Anubha; Matias-Garcia, Pamela R.; Meisinger, Christa; Meitinger, Thomas; Melander, Olle; Milaneschi, Yuri; Mishra, Pashupati P.; Mononen, Nina; Morris, Andrew P.; Mychaleckyj, Josyf C.; Nadkarni, Girish N.; Naito, Mariko; Nakatochi, Masahiro; Nalls, Mike A.; Nauck, Matthias; Nikus, Kjell; Ning, Boting; Nolte, Ilja M.; Nutile, Teresa; O'Donoghue, Michelle L.; O'Connell, Jeffrey; Olafsson, Isleifur; Orho-Melander, Marju; Parsa, Afshin; Pendergrass, Sarah A.; Penninx, Brenda W.J.H.; Pirastu, Mario; Preuss, Michael H.; Psaty, Bruce M.; Raffield, Laura M.; Raitakari, Olli T.; Rheinberger, Myriam; Rice, Kenneth M.; Rizzi, Federica; Rosenkranz, Alexander R.; Rossing, Peter; Rotter, Jerome I.; Ruggiero, Daniela; Ryan, Kathleen A.; Sabanayagam, Charumathi; Salvi, Erika; Schmidt, Helena; Schmidt, Reinhold; Scholz, Markus; Schöttker, Ben; Schulz, Christina-Alexandra; Sedaghat, Sanaz; Shaffer, Christian M.; Sieber, Karsten B.; Sim, Xueling; Sims, Mario; Snieder, Harold; Stanzick, Kira J.; Thorsteinsdottir, Unnur; Stocker, Hannah; Strauch, Konstantin; Stringham, Heather M.; Sulem, Patrick; Szymczak, Silke; Taylor, Kent D.; Thio, Chris H.L.; Tremblay, Johanne; Vaccargiu, Simona; van der Harst, Pim; van der Most, Peter J.; Verweij, Niek; Völker, Uwe; Wakai, Kenji; Waldenberger, Melanie; Wallentin, Lars; Wallner, Stefan; Wang, Judy; Waterworth, Dawn M.; White, Harvey D.; Willer, Cristen J.; Wong, Tien-Yin; Woodward, Mark; Yang, Qiong; Yerges-Armstrong, Laura M.; Zimmermann, Martina; Zonderman, Alan B.; Bergler, Tobias; Stefansson, Kari; Böger, Carsten A.; Pattaro, Cristian; Köttgen, Anna; Kronenberg, Florian; Heid, Iris M. (Peer reviewed; Journal article, 2022)
      Estimated glomerular filtration rate (eGFR) reflects kidney function. Progressive eGFR-decline can lead to kidney failure, necessitating dialysis or transplantation. Hundreds of loci from genome-wide association studies ...

    • The genetic organization of longitudinal subcortical volumetric change is stable throughout the lifespan running title: Genetics of subcortical lifespan change 

      Fjell, Anders Martin; Grydeland, Håkon; Wang, Yunpeng; Amlien, Inge; Bartrés-Faz, David; Brandmaier, Andreas M.; Düzel, Sandra; Elman, Jeremy; Franz, Carol; Håberg, Asta; Kietzmann, Tim C.; Kievit, Rogier A.; Kremen, William S.; Krogsrud, Stine Kleppe; Kühn, Simone; Lindenberger, Ulman; Macià, Didac; Mowinckel, Athanasia Monika; Nyberg, Lars; Panizzon, Matthew S.; Solé-Padullés, Cristina; Sørensen, Øystein; Westerhausen, Rene; Walhovd, Kristine B (Peer reviewed; Journal article, 2021)
      Development and aging of the cerebral cortex show similar topographic organization and are governed by the same genes. It is unclear whether the same is true for subcortical regions, which follow fundamentally different ...

    • Genetic polymorphisms associated with sleep-related phenotypes; relationships with individual nocturnal symptoms of insomnia in the HUNT study 

      Bragantini, Daniela; Sivertsen, Børge; Gehrman, Philip; Lydersen, Stian; Guzey, Ismail Cuneyt (Journal article; Peer reviewed, 2019)
      Background In recent years, several GWAS (genome wide association studies) of sleep-related traits have identified a number of SNPs (single nucleotides polymorphism) but their relationships with symptoms of insomnia are ...

    • Genetic predisposition to PEG-asparaginase hypersensitivity in children treated according to NOPHO ALL2008 

      Højfeldt, Sofie G; Wolthers, Benjamin Ole; Tulstrup, Morten; Abrahamsson, Jonas; Gupta, Ramneek; Harila-Saari, Arja; Heyman, Mats; Henriksen, Louise T; Jonsson, Olafur G.; Lähteenmäki, Päivi M.; Lund, Bendik; Pruunsild, Kaie; Vaitkeviciene, Goda; Schmiegelow, Kjeld; Albertsen, Birgitte K. (Peer reviewed; Journal article, 2018)
      Asparaginase is essential in childhood acute lymphoblastic leukaemia (ALL) treatment, however hypersensitivity reactions to pegylated asparaginase (PEG-asparaginase) hampers anti-neoplastic efficacy. Patients with ...

    • Genetic risk score associations for myocardial infarction are comparable in persons with and without rheumatoid arthritis: the population-based HUNT study 

      Rostami, Sina; Hoff, Mari; Dalen, Håvard; Hveem, Kristian; Videm, Vibeke (Peer reviewed; Journal article, 2020)
      Persons with rheumatoid arthritis (RA) have increased risk of myocardial infarction (MI). Overlapping associations with MI of weighted genetic risk scores (wGRS) for coronary artery disease (CAD) and RA is unknown in a ...

    • Genetic Susceptibility Loci in Genomewide Association Study of Cluster Headache 

      Harder, Aster V.E.; Winsvold, Bendik K S; Noordam, Raymond; Vijfhuizen, Lisanne S.; Børte, Sigrid; Kogelman, Lisette J.A.; de Boer, Irene; Tronvik, Erling Andreas; Rosendaal, Frits; Willems van Dijk, Ko; O'Connor, Emer; Fourier, Carmen; Thomas, Laurent; Kristoffersen, Espen Saxhaug; Fronczek, Rolf; Pozo-Rosich, Patricia; Jensen, Rigmor; Ferrari, Michel D.; Hansen, Thomas; Zwart, John-Anker; Terwindt, Gisela M.; van den Maagdenberg, Arn M.J.M (Peer reviewed; Journal article, 2021)
      Objective Identifying common genetic variants that confer genetic risk for cluster headache. Methods We conducted a case–control study in the Dutch Leiden University Cluster headache neuro-Analysis program (LUCA) study ...

    • Genetic variants associated with cardiometabolic abnormalities during treatment with selective serotonin reuptake inhibitors: a genome-wide association study 

      Fjukstad, Katrine Kveli; Athanasiu, Lavinia; Bahrami, Shahram; O`Connell, Kevin; van der Meer, Dennis; Bettella, Francesco; Dieset, Ingrid; Steen, Nils Eiel; Djurovic, Srdjan; Spigset, Olav; Andreassen, Ole Andreas (Peer reviewed; Journal article, 2021)
      Selective serotonin reuptake inhibitors (SSRIs) are prescribed both to patients with schizophrenia and bipolar disorder. Previous studies have shown associations between SSRI treatment and cardiometabolic alterations. The ...

    • Genetic variation and cognitive dysfunction in opioid-treated patients with cancer 

      Kurita, Geana Paula; Ekholm, Ola; Kaasa, Stein; Klepstad, Pål; Skorpen, Frank; Sjøgren, Per (Peer reviewed; Journal article, 2016)
      Background and purpose The effects of single‐nucleotide polymorphisms (SNPs) on the cognitive function of opioid‐treated patients with cancer until now have not been explored, but they could potentially be related to ...