Browsing St. Olavs hospital by Title

Now showing items 1567-1586 of 2460

    • Novel Synergistic Anti-Enteroviral Drug Combinations 

      Ianevski, Aleksandr; Zusinaite, Eva; Tenson, Tanel; Oksenych, Valentyn; Wang, Wei; Afset, Jan Egil; Bjørås, Magnar; Kainov, Denis (Peer reviewed; Journal article, 2022)
      Background: Enterovirus infections affect people around the world, causing a range of illnesses, from mild fevers to severe, potentially fatal conditions. There are no approved treatments for enterovirus infections. Methods: ...

    • NR4A2 is regulated by Gastrin and involved in gastrin-induced migration and invasion of gastric adenocarcinoma cells 

      Misund, Kristine; Selvik, Linn-Karina M.; Rao, Shalini; Nørsett, Kristin Gabestad; Bakke, Ingunn; Sandvik, Arne; Lægreid, Astrid; Bruland, Torunn; Prestvik, Wenche S; Thommesen, Liv (Peer reviewed; Journal article, 2013)
      The peptide hormone gastrin is known to play a role in differentiation, growth and apoptosis of cells in the gastric mucosa. In this study we demonstrate that gastrin induces Nuclear Receptor 4A2 (NR4A2) expression in the ...

    • NRF2 drives an oxidative stress response predictive of breast cancer 

      Wolowczyk, Camilla; Neckmann, Ulrike; Aure, Miriam Ragle; Hall, Martina; Johannessen, Bjarne; Zhao, Sen; Skotheim, Rolf I.; Andersen, Sonja Benedikte; Zwiggelaar, Rosalie Theda Margien; Steigedal, Tonje S.; Lingjærde, Ole Christian; Sahlberg, Kristine Kleivi; Almaas, Eivind; Bjørkøy, Geir (Peer reviewed; Journal article, 2022)
      Many breast cancer patients are diagnosed with small, well-differentiated, hormone receptor-positive tumors. Risk of relapse is not easily identified in these patients, resulting in overtreatment. To identify metastasis-related ...

    • Nucleoside Analogues Are Potent Inducers of Pol V-mediated Mutagenesis 

      Sumabe, Balagra Kasim; Ræder, Synnøve Brandt; Røst, Lisa M.; Sharma, Animesh; Donkor, Eric S.; Mosi, Lydia; Duodu, Samuel; Bruheim, Per; Otterlei, Marit (Peer reviewed; Journal article, 2021)
      Drugs targeting DNA and RNA in mammalian cells or viruses can also affect bacteria present in the host and thereby induce the bacterial SOS system. This has the potential to increase mutagenesis and the development of ...

    • Number of Chronic Nighttime Insomnia Symptoms and Risk of Chronic Widespread Pain and Pain-Related Disability: The HUNT Study 

      Skarpsno, Eivind S.; Mork, Paul Jarle; Knut, Hagen; Nilsen, Tom Ivar Lund; Anna, Marcuzzi (Peer reviewed; Journal article, 2019)
      Study Objectives: To examine the association between the number of chronic nighttime insomnia symptoms and the risk of chronic widespread pain (CWP) and pain-related disability. Methods: A prospective study of 10,847 ...

    • Nurses experience increased clinical and organisational competence by working with a medical quality register, RevNatus – a qualitative study. 

      Bjørngaard, Hilde; Koksvik, Hege; Jakobsen, Bente; Grønning, Kjersti (Peer reviewed; Journal article, 2022)
      Background RevNatus is a consent-based, nationwide medical quality register that collects data on patients with inflammatory rheumatic diseases during pregnancy and one year postpartum. The entering of data takes place ...

    • Nurses' experiences of compassionate care in the palliative pathway 

      Tarberg, Anett Skorpen; Landstad, Bodil J.; Hole, Torstein; Thronæs, Morten; Kvangarsnes, Marit (Peer reviewed; Journal article, 2020)
      Aims and objectives The aim was to explore how nurses experience compassionate care for patients with cancer and family caregivers in different phases of the palliative pathway. Background Compassion is fundamental ...

    • Nurses' perceptions of patient participation in the myocardial infarction pathway 

      Bårdsgjerde, Elise Kvalsund; Landstad, Bodil; Hole, Torstein; Nylenna, Magne; Gjeilo, Kari Hanne; Kvangarsnes, Marit (Peer reviewed; Journal article, 2020)
      Aim To explore nurses' perceptions of patient participation in different phases of the myocardial infarction pathway. Design Qualitative design with a hermeneutical approach. Methods Five focus groups were ...

    • Nursing-sensitive quality indicators for quality improvement in Norwegian nursing homes – a modified Delphi study 

      Tevik, Kjerstin Elisabeth; Helvik, Anne-Sofie; Stensvik, Geir-Tore; Nordberg, Marion Skallerud; Nakrem, Sigrid (Peer reviewed; Journal article, 2023)
      Background Use of nursing-sensitive quality indicators (QIs) is one way to monitor the quality of care in nursing homes (NHs). The aim of this study was to develop a consensus list of nursing-sensitive QIs for Norwegian ...

    • Nutcracker syndrome mimicking new daily persistent headache: A case report 

      Stubberud, Anker; Cheema, Sanjay; Tronvik, Erling Andreas; Matharu, Manjit (Peer reviewed; Journal article, 2020)
      Introduction Compression of the duodenum and left renal vein between the aorta and superior mesenteric artery usually leads to symptoms of proximal bowel obstruction or hematuria and, more rarely, nonspecific mild ...

    • Nutritional experiences in head and neck cancer patients 

      Sandmæl, Jon Arne; Sand, Kari; Bye, Asta; Solheim, Tora Skeidsvoll; Oldervoll, Line Merethe; Helvik, Anne-Sofie (Journal article; Peer reviewed, 2019)
      Objective Extensive research has documented the negative nutritional impact of head neck cancer (HNC) treatment, but few studies have addressed the patients' experiences. The purpose of this study was to describe how ...

    • Nye diabetesmidler – til nytte for mange, til skade for noen 

      Åsvold, Bjørn Olav (Journal article; Peer reviewed, 2023)

    • Nye sentre skal gi flere kliniske studier i Norge 

      Skoie, Inger Marie; Skogås, Jan Gunnar; Langø, Thomas; Myhr, Kjell-Morten; Myhre, Peder Langeland; Goll, Rasmus; Fretland, Signe Øien; Helland, Åslaug (Journal article; Peer reviewed, 2023)
      Seks NorTrials-sentre for behandlingsforskning er etablert ved universitetssykehusene. Målet er å øke antallet kliniske studier og forbedre pasientbehandlingen.

    • Nytt redningshelikopters innvirkning på redningstjenestens oppdragsprofil 

      Haugland, Helge; Klüver, Jens; Bottolfs, Bjørn; Singstad, Asbjørn; Dale, Jostein (Peer reviewed; Journal article, 2022)
      BAKGRUNN Byttet av redningshelikopter fra Sea King til SAR Queen har vært omdiskutert. Flere sykehus kan ikke lenger ta imot redningshelikopter pga. det økte vindtrykket fra SAR Queen. Av samme grunn har det vært usikkert ...

    • Nytt verktøy for tolkning av farmakogenetiske analyser 

      Tuv, Silja Skogstad; Spigset, Olav; Jensen, Elena; Vethe, Nils Tore; Nordal, Kristin (Peer reviewed; Journal article, 2023)
      Utilgjengelig kunnskap om tolkning av genvarianter som kan påvirke legemiddelrespons, er en barriere for implementering av farmakogenetikk. Vi har utviklet et nettbasert verktøy hvor man kan utføre spørringer og få ...

    • Obesity does not protect from subarachnoid haemorrhage: Pooled analysis of 3 large prospective Nordic cohorts 

      Rautalin, Ilari; Kaprio, Jaakko; Ingebrigtsen, Tor; Jousilahti, Pekka; Løchen, Maja-Lisa; Romundstad, Pål Richard; Salomaa, Veikko; Vik, Anne; Wilsgaard, Tom; Mathiesen, Ellisiv B.; Sandvei, Marie Søfteland; Korja, Miikka (Journal article; Peer reviewed, 2021)
      Background and Purpose: Several population-based cohort studies have related higher body mass index (BMI) to a decreased risk of subarachnoid hemorrhage (SAH). The main objective of our study was to investigate whether ...

    • Observational study on chest pain during the Covid-19 pandemic: changes and characteristics of visits to a Norwegian emergency department during the lockdown 

      Grande, Mikkel; Bjørnsen, Lars Petter Bache-Wiig; Næss-Pleym, Lars E.; Laugsand, Lars Erik; Grenne, Bjørnar (Peer reviewed; Journal article, 2022)
      The Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2) emerged in Wuhan, China in December 2019, and spread rapidly worldwide causing the Coronavirus Disease 2019 (Covid-19) pandemic [1]. Italy was the first ...

    • Observer agreement of imaging measurements used for evaluation of dentofacial deformity in juvenile idiopathic arthritis 

      Fischer, Johannes Maria; Halbig, Josefine Mareile; Augdal, Thomas Angell; Angenete, Oskar W; Stoustrup, Peter; Kristensen, Kasper Dahl; Skeie, Marit Slåttelid; Tylleskär, Karin; Rosén, Annika; Shi, Xie-Qi; Rosendahl, Karen (Peer reviewed; Journal article, 2022)
      Objectives: To examine the precision of imaging measures commonly used to assess mandibular morphology in children and adolescents with juvenile idiopathic arthritis (JIA). Secondly, to compare cone-beam computed ...

    • Obsessive-compulsive disorder (OCD) in patients with first- episode psychosis (FEP): A prospective study 

      Hagen, Kristen; Solem, Stian; Larsen, Tor Ketil; Joa, Inge; Kvale, Gerd; Hansen, Bjarne (Journal article; Peer reviewed, 2014)

    • Occupational health and safety in agriculture– a brief report on organization, legislation and support in selected european countries 

      Jakob, Martina Carola; Santa, Dushica; Holte, Kari Anne; Sikkeland, Inger Johanne; Hilt, Bjørn; Lundqvist, Peter (Peer reviewed; Journal article, 2021)
      Introduction and objective: Agriculture and forestry are among the most dangerous professions in Europe, with a high level of accidents affecting the sustainability and viability of the sector. International conventions, ...