Blar i St. Olavs hospital på tittel

Viser treff 1547-1566 av 2441

    • Novel genomic islands and a new vanD-subtype in the first sporadic VanD-type vancomycin resistant enterococci in Norway 

      Al-Rubaye, Mushtaq; Janice, Jessin; Bjørnholt, Jørgen Vildershøj; Jakovljev, Aleksandra; Hultström, Maria Elisabeth; Sundsfjord, Arnfinn; Hegstad, Kristin (Peer reviewed; Journal article, 2021)
      Background - Vancomycin-resistant enterococci (VRE) represent several types of transferable vancomycin resistance gene clusters. The vanD type, associated with moderate to high level vancomycin resistance, has only ...

    • Novel Insights Into the Effects of Interleukin 6 Antagonism in Non-ST-Segment-Elevation Myocardial Infarction Employing the SOMAscan Proteomics Platform 

      George, Marc J; Kleveland, Ola; Garcia-Hernandez, Jorge; Palmen, Jutta; Lovering, Ruth; Wiseth, Rune; Aukrust, Pål; Engmann, Jorgen; Damås, Jan Kristian; Hingorani, Aroon D; Gullestad, Lars; Casas, Juan P; Ueland, Thor (Peer reviewed; Journal article, 2020)
      Background Interleukin 6 concentration is associated with myocardial injury, heart failure, and mortality after myocardial infarction. In the Norwegian tocilizumab non-ST-segment-elevation myocardial infarction trial, the ...

    • A novel MRI index for paraspinal muscle fatty infiltration: reliability and relation to pain and disability in lumbar spinal stenosis: results from a multicentre study 

      BANITALEBI, HASAN; Aaen, Jørn Ståle; Storheim, Kjersti; Negård, Anne; Myklebust, Tor Åge; Grotle, Margreth; Hellum, Christian; Espeland, Ansgar; Anvar, Masoud D; Indrekvam, Kari; Weber, Clemens; Brox, Jens Ivar; Brisby, Helena; Hermansen, Erland (Peer reviewed; Journal article, 2022)
      Background Fatty infiltration of the paraspinal muscles may play a role in pain and disability in lumbar spinal stenosis. We assessed the reliability and association with clinical symptoms of a method for assessing fatty ...

    • Novel Peptides Targeting the β-Clamp Rapidly Kill Planktonic and Biofilm Staphylococcus epidermidis Both in vitro and in vivo 

      Ræder, Synnøve Brandt; Sandbakken, Erik Thorvaldsen; Nepal, Anala; Løseth, Kirsti; Bergh, Kåre; Witsø, Eivind; Otterlei, Marit (Peer reviewed; Journal article, 2021)
      Antimicrobial resistance is an increasing threat to global health and challenges the way we treat infections. Peptides containing the PCNA interacting motif APIM (APIM-peptides) were recently shown to bind to the bacterial ...

    • A novel serum calprotectin (MRP8/14) particle-enhanced immuno-turbidimetric assay (sCAL turbo) helps to differentiate systemic juvenile idiopathic arthritis from other diseases in routine clinical laboratory settings 

      Foell, Dirk; Saers, Melanie; Park, Carolin; Brix, Ninna; Glerup, Mia; Kessel, Christoph; Wittkowski, Helmut; Hinze, Claas; Berntson, Lillemor; Fasth, Anders; Myrup, Charlotte; Nordal, Ellen Berit; Rygg, Marite; Hasle, Henrik; Albertsen, Birgitte Klug; Herlin, Troels; Holzinger, Dirk; Niederberger, Christian; Schlüter, Bernhard (Peer reviewed; Journal article, 2023)
      Background Differential diagnosis in children with signs of unprovoked inflammation can be challenging. In particular, differentiating systemic juvenile idiopathic arthritis (SJIA) from other diagnoses is difficult. We ...

    • A novel somatic mutation in GNB2 provides new insights to the pathogenesis of Sturge-Weber syndrome 

      Fjær, Roar; Marciniak, Katarzyna; Sundnes, Olav; Hjorthaug, Hanne; Sheng, Ying; Hammarström, Clara Louise; Sitek, Jan Cezary; Vigeland, Magnus Dehli; Backe, Paul Hoff; Øye, Ane-Marte; Hol, Johanna; Stav-Noraas, Tor Espen; Uchiyama, Yuri; Matsumoto, Naomichi; Comi, Anne; Pevsner, Jonathan; Haraldsen, Guttorm; Selmer, Kaja Kristine (Peer reviewed; Journal article, 2021)
      Sturge–Weber syndrome (SWS) is a neurocutaneous disorder characterized by vascular malformations affecting skin, eyes and leptomeninges of the brain, which can lead to glaucoma, seizures and intellectual disability. The ...

    • Novel Synergistic Anti-Enteroviral Drug Combinations 

      Ianevski, Aleksandr; Zusinaite, Eva; Tenson, Tanel; Oksenych, Valentyn; Wang, Wei; Afset, Jan Egil; Bjørås, Magnar; Kainov, Denis (Peer reviewed; Journal article, 2022)
      Background: Enterovirus infections affect people around the world, causing a range of illnesses, from mild fevers to severe, potentially fatal conditions. There are no approved treatments for enterovirus infections. Methods: ...

    • NR4A2 is regulated by Gastrin and involved in gastrin-induced migration and invasion of gastric adenocarcinoma cells 

      Misund, Kristine; Selvik, Linn-Karina M.; Rao, Shalini; Nørsett, Kristin Gabestad; Bakke, Ingunn; Sandvik, Arne; Lægreid, Astrid; Bruland, Torunn; Prestvik, Wenche S; Thommesen, Liv (Peer reviewed; Journal article, 2013)
      The peptide hormone gastrin is known to play a role in differentiation, growth and apoptosis of cells in the gastric mucosa. In this study we demonstrate that gastrin induces Nuclear Receptor 4A2 (NR4A2) expression in the ...

    • NRF2 drives an oxidative stress response predictive of breast cancer 

      Wolowczyk, Camilla; Neckmann, Ulrike; Aure, Miriam Ragle; Hall, Martina; Johannessen, Bjarne; Zhao, Sen; Skotheim, Rolf I.; Andersen, Sonja Benedikte; Zwiggelaar, Rosalie Theda Margien; Steigedal, Tonje S.; Lingjærde, Ole Christian; Sahlberg, Kristine Kleivi; Almaas, Eivind; Bjørkøy, Geir (Peer reviewed; Journal article, 2022)
      Many breast cancer patients are diagnosed with small, well-differentiated, hormone receptor-positive tumors. Risk of relapse is not easily identified in these patients, resulting in overtreatment. To identify metastasis-related ...

    • Nucleoside Analogues Are Potent Inducers of Pol V-mediated Mutagenesis 

      Sumabe, Balagra Kasim; Ræder, Synnøve Brandt; Røst, Lisa M.; Sharma, Animesh; Donkor, Eric S.; Mosi, Lydia; Duodu, Samuel; Bruheim, Per; Otterlei, Marit (Peer reviewed; Journal article, 2021)
      Drugs targeting DNA and RNA in mammalian cells or viruses can also affect bacteria present in the host and thereby induce the bacterial SOS system. This has the potential to increase mutagenesis and the development of ...

    • Number of Chronic Nighttime Insomnia Symptoms and Risk of Chronic Widespread Pain and Pain-Related Disability: The HUNT Study 

      Skarpsno, Eivind S.; Mork, Paul Jarle; Knut, Hagen; Nilsen, Tom Ivar Lund; Anna, Marcuzzi (Peer reviewed; Journal article, 2019)
      Study Objectives: To examine the association between the number of chronic nighttime insomnia symptoms and the risk of chronic widespread pain (CWP) and pain-related disability. Methods: A prospective study of 10,847 ...

    • Nurses experience increased clinical and organisational competence by working with a medical quality register, RevNatus – a qualitative study. 

      Bjørngaard, Hilde; Koksvik, Hege; Jakobsen, Bente; Grønning, Kjersti (Peer reviewed; Journal article, 2022)
      Background RevNatus is a consent-based, nationwide medical quality register that collects data on patients with inflammatory rheumatic diseases during pregnancy and one year postpartum. The entering of data takes place ...

    • Nurses' experiences of compassionate care in the palliative pathway 

      Tarberg, Anett Skorpen; Landstad, Bodil J.; Hole, Torstein; Thronæs, Morten; Kvangarsnes, Marit (Peer reviewed; Journal article, 2020)
      Aims and objectives The aim was to explore how nurses experience compassionate care for patients with cancer and family caregivers in different phases of the palliative pathway. Background Compassion is fundamental ...

    • Nurses' perceptions of patient participation in the myocardial infarction pathway 

      Bårdsgjerde, Elise Kvalsund; Landstad, Bodil; Hole, Torstein; Nylenna, Magne; Gjeilo, Kari Hanne; Kvangarsnes, Marit (Peer reviewed; Journal article, 2020)
      Aim To explore nurses' perceptions of patient participation in different phases of the myocardial infarction pathway. Design Qualitative design with a hermeneutical approach. Methods Five focus groups were ...

    • Nursing-sensitive quality indicators for quality improvement in Norwegian nursing homes – a modified Delphi study 

      Tevik, Kjerstin Elisabeth; Helvik, Anne-Sofie; Stensvik, Geir-Tore; Nordberg, Marion Skallerud; Nakrem, Sigrid (Peer reviewed; Journal article, 2023)
      Background Use of nursing-sensitive quality indicators (QIs) is one way to monitor the quality of care in nursing homes (NHs). The aim of this study was to develop a consensus list of nursing-sensitive QIs for Norwegian ...

    • Nutcracker syndrome mimicking new daily persistent headache: A case report 

      Stubberud, Anker; Cheema, Sanjay; Tronvik, Erling Andreas; Matharu, Manjit (Peer reviewed; Journal article, 2020)
      Introduction Compression of the duodenum and left renal vein between the aorta and superior mesenteric artery usually leads to symptoms of proximal bowel obstruction or hematuria and, more rarely, nonspecific mild ...

    • Nutritional experiences in head and neck cancer patients 

      Sandmæl, Jon Arne; Sand, Kari; Bye, Asta; Solheim, Tora Skeidsvoll; Oldervoll, Line Merethe; Helvik, Anne-Sofie (Journal article; Peer reviewed, 2019)
      Objective Extensive research has documented the negative nutritional impact of head neck cancer (HNC) treatment, but few studies have addressed the patients' experiences. The purpose of this study was to describe how ...

    • Nye diabetesmidler – til nytte for mange, til skade for noen 

      Åsvold, Bjørn Olav (Journal article; Peer reviewed, 2023)

    • Nye sentre skal gi flere kliniske studier i Norge 

      Skoie, Inger Marie; Skogås, Jan Gunnar; Langø, Thomas; Myhr, Kjell-Morten; Myhre, Peder Langeland; Goll, Rasmus; Fretland, Signe Øien; Helland, Åslaug (Journal article; Peer reviewed, 2023)
      Seks NorTrials-sentre for behandlingsforskning er etablert ved universitetssykehusene. Målet er å øke antallet kliniske studier og forbedre pasientbehandlingen.

    • Nytt redningshelikopters innvirkning på redningstjenestens oppdragsprofil 

      Haugland, Helge; Klüver, Jens; Bottolfs, Bjørn; Singstad, Asbjørn; Dale, Jostein (Peer reviewed; Journal article, 2022)
      BAKGRUNN Byttet av redningshelikopter fra Sea King til SAR Queen har vært omdiskutert. Flere sykehus kan ikke lenger ta imot redningshelikopter pga. det økte vindtrykket fra SAR Queen. Av samme grunn har det vært usikkert ...