Browsing Institutt for sirkulasjon og bildediagnostikk by Title
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Sepsis i akuttmottaket ved St. Olavs Hospital - En retrospektiv analyse av behandlingsforløp og håndtering av pasienter med sepsis
(Master thesis, 2015)Bakgrunn: Sepsis er en vanlig problemstilling i sykehus verden over, og flere studier har vist at insidensen er økende. På grunn av framgang i diagnostikk og behandling har mortaliteten ved sepsis gått ned, men den er ... -
Serum and urine concentrations of morphine and morphine metabolites in patients with advanced cancer receiving continuous intravenous morphine: An observational study Cancer palliative care
(Peer reviewed; Journal article, 2015)Background:The feasibility and clinical implication of drug monitoring of morphine, morphine-6-glucuronide (M6G)and morphine-3-glucuronide (M3G) need further investigation. This study aimed to determine what predicts ... -
Serum Concentrations and Pharmacokinetics of Tranexamic Acid after Two Means of Topical Administration in Massive Weight Loss Skin-Reducing Surgery
(Journal article; Peer reviewed, 2019)Background: Topical administration of tranexamic acid to reduce bleeding is receiving increasing attention, as it is inexpensive, simple, and possibly beneficial in most surgery. Concerns regarding potential systemic adverse ... -
Serum cytokine patterns in first half of pregnancy
(Journal article; Peer reviewed, 2019)Introduction Human pregnancy is a state of elevated maternal systemic inflammation, and pregnancy complications are often associated with a dysfunctional immune response. The network of cytokines reflects this complex ... -
Serum cytokine profiles in patients with prostate cancer
(Master thesis, 2014)Prostate cancer (PCa) is the most commonly diagnosed malignancy and the third leading cause of cancer death among men in western countries. The high incidence of prostate cancer underscores urgent need for clinical indicators ... -
Serum Levels of Choline-Containing Compounds Are Associated with Aerobic Fitness Level: The HUNT-Study
(Journal article; Peer reviewed, 2012)Background: Cardiovascular disease (CVD) is a leading cause of death worldwide, and the number of people at risk is continuously growing. New methods for early risk prediction are therefore needed to actuate prevention ... -
Serum levels of inflammation-related markers and metabolites predict response to neoadjuvant chemotherapy with and without bevacizumab in breast cancers
(Journal article; Peer reviewed, 2019)Angiogenesis is necessary for tumor growth and has been targeted in breast cancer; however, it is unclear which patients will respond and benefit from antiangiogenic therapy. We report noninvasive monitoring of patient ... -
Serum lipoprotein(a) is not modified by interleukin-6 receptor antagonism or associated with inflammation in non-ST-elevation myocardial infarction
(Journal article; Peer reviewed, 2018)Background The IL-6 receptor antagonist tocilizumab has been shown to attenuate the proatherogenic lipoprotein a [Lp(a)] in rheumatoid arthritis. We evaluated if a single dose of tocilizumab reduced Lp(a) in patients with ... -
Serum PCSK9 is modified by interleukin-6 receptor antagonism in patients with hypercholesterolaemia following non-ST-elevation myocardial infarction
(Journal article; Peer reviewed, 2018)Objective It is unclear if activation of inflammatory pathways regulates proprotein convertase subtilisin-kexin type 9 (PCSK9) levels. Approach We evaluated (1) the temporal course of serum PCSK9 during hospitalisation ... -
Sex differences in asthma control: the HUNT study
(Master thesis, 2016)Background: Asthma control is hypothesized to be influenced by sex; however, studies investigating sex differences in asthma control are few and results are conflicting. Objective: To our knowledge, no published peer-reviewed ... -
Sex differences in exercise respone in type 2 diabetes
(Master thesis, 2019)Background: Type2 diabetes (T2D) is a global health problem, which increases the risk of cardiovascular disease (CVD). Aerobic capacity is lower in T2D individuals compared to healthy, and women with T2D have even lower ... -
Sex-specific outcome disparities in very old patients admitted to intensive care medicine: a propensity matched analysis
(Peer reviewed; Journal article, 2020)Female and male very elderly intensive patients (VIPs) might differ in characteristics and outcomes. We aimed to compare female versus male VIPs in a large, multinational collective of VIPs with regards to outcome and ... -
SFRP4 gene expression is increased in aggressive prostate cancer
(Journal article; Peer reviewed, 2017)Increased knowledge of the molecular differences between indolent and aggressive prostate cancer is needed for improved risk stratification and treatment selection. Secreted frizzled-related protein 4 (SFRP4) is a modulator ... -
Short high-intensity interval training: a time efficient exercise strategy for overweight and obese compared with regular endurance training
(Master thesis, 2012)Background: Aerobic training plays an important role in preventing and treating overweight and obesity. The physical activity recommendation to improve health is set to a minimum of 150 minutes of ... -
Short- or long-acting opioids in chronic non-malignant pain: Which are better?”
(Doctoral thesis at NTNU;2015:258, Doctoral thesis, 2015)Background Chronic pain affects 15-30 % of the western population. Chronic pain is associated with a reduced quality of life for the individual, an increased consumption of healthcare resources and a loss of productivity ... -
The short-term impact of methylprednisolone on patient-reported sleep in patients with advanced cancer in a randomized, placebo-controlled, double-blind trial
(Peer reviewed; Journal article, 2020)Purpose: Although corticosteroids are frequently used in patients with advanced cancer, few studies have examined the impact of these drugs on patient-reported sleep. We aimed to examine the short-term impact of ... -
Sidenafil Pre-Treatment Promotes Decompression Sickness in Rats
(Journal article; Peer reviewed, 2013)Vascular bubble formation after decompression contributes to endothelial injuries which form the basis for the development of decompression sickness (DCS). Nitric oxide (NO) is a powerful vasodilator that contributes to ... -
Silent voices: Family caregivers' narratives of involvement in palliative care
(Journal article; Peer reviewed, 2019)Aim To explore how family caregivers experience involvement in palliative care. Design A qualitative design with a narrative approach was used. Methods Purposive sampling and narrative interviews were conducted. Eleven ... -
Simple and robust intravital microscopy procedures in hybrid TIE2GFP-BALB/c transgenic mice
(Peer reviewed; Journal article, 2019)Purpose The endeavor of deciphering intricate phenomena within the field of molecular medicine dictates the necessity to investigate tumor/disease microenvironment real-time on cellular level. We, hereby, design simple and ... -
Simulation-based Training and Assessment in Minimally Invasive Surgery Exploration and Validation
(Doctoral theses at NTNU;2019:323, Doctoral thesis, 2019)Changes in surgical techniques and public attention to surgeons’ competencies in general, created a growth in simulation-based training in the late 90’s. The introduction of minimally invasive surgery, with its distinct ...