Blar i Institutt for klinisk og molekylær medisin på dokumenttype "Master thesis"
Viser treff 1-20 av 478
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5-ASA Affects the PPAR-gamma Protein Expression and Chemokine Release in Intestinal Epithelial Cells
(Master thesis, 2024)Bakgrunn: Inflammatorisk tarm sykdom (IBD) er en kronisk immunologisk sykdom som består av ulcerøs kolitt (UC) og Crohn’s sykdom (CD). De karakteriseres av betennelse i fordøyelsessystemet, oftest i tarmene. Hva som ... -
A Computational Analysis of Motif-Negative VDR-DNA Interaction and Possible Explanations of Its Mechanism of Interaction
(Master thesis, 2014)Transcription factor binding to DNA has generally been assumed to be as a result of the recognition of sequence-specific motifs in the transcription factor binding sites. Recent studies have however shown several examples ... -
A Novel Photosensitizer for PET-Imaging and Cancer Treatment —In vitro studies (AY-27 cells)
(Master thesis, 2021) -
A prospective multicenter register study exploring health-related quality of life in women with Sjøgren's syndrome during pregnancy
(Master thesis, 2024)Sammendrag Introduksjon: Det er gjort få studier på helserelatert livskvalitet hos kvinner med Sjøgren's syndrom (SS) under svangerskap og gravide kvinner med SS anses som risikosvangerskap, med økt risiko for uheldige ... -
A prospective multicenter register study exploring health-related quality of life in women with Sjøgren's syndrome during pregnancy.
(Master thesis, 2024)Sammendrag Introduksjon: Det er gjort få studier på helserelatert livskvalitet hos kvinner med Sjøgren's syndrom (SS) under svangerskap og gravide kvinner med SS anses som risikosvangerskap, med økt risiko for uheldige ... -
A Study of Toll-like Receptors in Trophoblasts, and the Influence of Cytomegalovirus Infection
(Master thesis, 2012)Toll-like receptors (TLRs) act as sensors against invading pathogens and endogenous danger signals, and are critical mediators of inflammatory immune responses. During pregnancy, intrauterine activation of TLRs might evoke ... -
A Toll-like receptor 7/8 ligand secreted by a myeloma cell line induces primary bone marrow stromal cells to produce survival promoting cytokines
(Master thesis, 2015)Multiple myeloma (MM) is a cancer of plasma cells, which accumulate in the bone marrow (BM). The BM milieu provides MM cells with survival and proliferation signals. Toll-like receptors (TLRs) are immune receptors that ... -
Allmennleger og generisk bytte av legemidler
(Master thesis, 2012)Bakgrunn: Ordningen med generisk bytte ble innført i Norge i 2001. Den innebærer at det i apotek kan byttes fra det legen har forskrevet til et generisk likeverdig legemiddel, og at kun det billigste alternativet dekkes ... -
An Agile Approach to Novel Recombinant Antithrombin Production for use in Biologics Development
(Master thesis, 2019)Background: Sepsis is a deadly medical condition caused by a runaway inflammatory response to systemic infection in which the release of extracellular cytotoxic histones has been linked to disease progression. Heparin ... -
An Attempt to Elucidate the Genes Encoding the Surface Exposed Proteins R3, Z1 and Z2 in Two Strains of Streptococcus agalactiae from Zimbabwe
(Master thesis, 2014)Surface exposed proteins of Streptococcus agalactiae (GBS) may be used in serotyping and may have a potential role as vaccine candidates. The proteins R3 and the recently discovered Z1 and Z2 were found to be important ... -
Analyse av eksogene og endogene opioide peptider i dry blood spots ved bruk av HPLC-MS
(Master thesis, 2019)Opioide peptider forekommer både som eksogene- og som endogene peptider. Endogene peptider er kroppens egne peptider som blant annet funger som eget kontrollsystem på smerter, mens eksogene peptider hovedsakelig kommer ... -
Analysis of CD4+ Th1 cells in immunity to intracellular Mycobacterium avium infection
(Master thesis, 2013)Mycobacterial infections are considered a major health problem internationally. Mycobacterium tuberculosis (Mtb), the infectious agent causing tuberculosis, kills 1.4 million people each year. Other non-tuberculous species ... -
Analysis of host immune parameters during M. avium infection
(Master thesis, 2012)The goal of this study was to establish and optimize methods to analyze effector cytokine levels and other parameters in murine tissue and plasma samples. These methods should then be used to study the role of regulatory ... -
Analysis of mycobacteria-specific CD4+ T cell cytokine responses and memory differentiation in HIV patients and healthy controls
(Master thesis, 2013)Among people living with HIV/AIDS, tuberculosis caused by Mycobacterium tuberculosis (MTB) is the main cause of mortality with 430 000 deaths in 2011. Multidrug-resistant tuberculosis is on the rise, and no effective vaccine ... -
Analysis of mycobacteria-specific T cell functions in HIV-infected individuals and healthy controls
(Master thesis, 2012)Tuberculosis caused by Mycobacterium tuberculosis (MTb) continues to represent a major public health problem worldwide and it is the main cause of death among people living with HIV/AIDS. Mycobacteria-specific CD4 T cells ... -
Analysis of mycobacteria-specific T cell functions in HIV-infected individuals and healthy controls
(Master thesis, 2012)Tuberculosis caused by Mycobacterium tuberculosis (MTb) continues to represent a major public health problem worldwide and it is the main cause of death among people living with HIV/AIDS. Mycobacteria-specific CD4 T cells ... -
Androgen receptor expression in breast cancer subtypes
(Master thesis, 2016)Background The androgen receptor (AR) is frequently expressed in breast cancer, and associated with good prognosis in ER-positive breast cancers. Due to its high prevalence, AR is also a possible target for therapeutic ... -
Antibiotikabehandling ved nedre luftveisinfeksjoner i sykehus; etterlevelse av nasjonal retningslinje
(Master thesis, 2023)Bakgrunn: Antibiotikaresistens er et globalt helseproblem. Selv om forekomsten av resistens ikke er like utbredt i Norge kan dette raskt endre seg. Nasjonal retningslinje for antibiotika i sykehus er i Norge et viktige ... -
Antibiotikaforskrivning ved samfunnservervet pneumoni ved Medisinsk klinikk, Helse Møre og Romsdal
(Master thesis, 2019)Sammendrag Bakgrunn: Samfunnservervet pneumoni (CAP) er en av de vanligste årsakene til hospitalisering og pasienter med CAP assosieres med høy morbiditet og mortalitet, spesielt hos eldre. Det er også en hyppig indikasjon ... -
Antiviral Combinations for Treatment of Enteroviral Infections
(Master thesis, 2024)Enterovirus er den vanligste årsaken til forkjølelsessykdom, men kan også ligge til grunn for mer alvorlige sykdommer, som diabetes, meningitt, munn- og klovsyke, og paralyse. Til tross for deres store utbredelse og relevans, ...